Clinical trials: Brain Activity
Stroke with Hemiparesis, Stroke
Impact of the BOOST GAIT Program on Gait Recovery and Functional Mobility After Stroke
The overarching goal is to determine if the BOOST GAIT program can improve functional mobility in patients with stroke who are undergoing inpatient rehabilitation and have some walking function, through the application of…
- Trial name
- BOOST GAIT (NCT06612359)
- Testing
- BOOST GAIT Program
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Hasselt University
Stroke
Activity Levels and Rehabilitation Outcomes of Patients Post-stroke
Patients admitted to the in-patient rehabilitation center with a diagnosis of stroke will be recruited into the study. The participants will wear two activity monitors (one commercial grade and one research grade) for the…
- Trial name
- NCT03257111
- Testing
- activity monitors
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Florida Gulf Coast University
COVID-19 Respiratory Infection
Cardiopulmonary Rehabilitation in Long COVID-19 Patients With Persistent Breathlessness and Fatigue
The objective of this project is to assess the effects of a 2-month cardiopulmonary rehabilitation program on cardiorespiratory fitness in long COVID19 patients.
- Trial name
- COVID-Rehab (NCT05035628)
- Testing
- Cardiopulmonary exercise training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Louis Bherer
Dementia, Pain
Preventing Aggression In Veterans With Dementia (PAVED) - Telephone Sub-Study With Rural Veterans
Aggression, a common symptom in persons with dementia, is linked with multiple treatable etiologies such as pain, depression, caregiver burden, and caregiver relationships.
- Trial name
- PAVED-T (NCT01385007)
- Testing
- Preventing Aggression in Veterans with Dementia (PAVeD)
- Volunteers
- 40 people
- Sponsor
- Michael E. DeBakey VA Medical Center
Coordination Impairment
Physical Activity on Eye Hand Coordination Post Strabismus Surgery
The aim of this study is to determine the effect of physical activity on eye hand coordination in patient with amblyopia after strabismus surgery.
- Trial name
- NCT06759792
- Testing
- eye hand coordination exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Amany Refaat Mohamed Abdel Wahid
Dementia
Individualized Music Playlist Based on ISO Principle for De-escalation of Agitation in Dementia
The goal of this clinical trial is to evaluate the efficacy of an Individualized Music Playlist (InMP) composed of preferred music genres sequenced according to the ISO-Principle, for the immediate de-escalation of agitation in…
- Trial name
- NCT06104436
- Testing
- Individualized music playlist, Preferred music, Usual care
- Where
- Hong Kong
- Volunteers
- 81 people
- Sponsor
- The Hong Kong Polytechnic University
Alzheimer Disease, Dementia
MEMORI Corps: Activity-based Companion Care for Dementia
This project adapts a novel activity-based companion care model, the Making Engagement Meaningful through Organized Routine Interaction (MEMORI) Corps intervention, for a virtual delivery format, and then implements the…
- Trial name
- MEMORI Corps (NCT03896711)
- Testing
- MEMORI Corps program, Augmented Waitlist Control
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cerebral Palsy
Task Oriented Activities Based on NDT Therapy Principles
Cerebral palsy (CP) is one of the primary causes of disability effecting majority of pediatric population. Cerebral Palsy is considered a neurological disorder caused by a non-progressive brain injury or malformation that occurs…
- Trial name
- NCT05903729
- Testing
- Neurodevelopmental therapy treatment, conventional physiotherapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Depression
Evaluation of Depression Symptoms and Brain Activity Associated With Response to Treatment of Depression
This study will use measurements of depression symptoms and brain activity to determine what factors may influence an individual's response to treatment for depression.
- Trial name
- NCT00200902
- Testing
- Venlafaxine (Effexor), Duloxetine (Cymbalta), Escitalopram (Lexapro), Interpersonal Clinical Interaction (ICI)
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder, EEG With Periodic Abnormalities
Safety and Efficacy of tPBM for Epileptiform Activity in Autism
For this study, the proposed intervention will be noninvasively delivered near infra-red (NIR) light - transcranial Photobiomodulation (tPBM) - to the brains of autistic children with abnormal EEGs with epileptiform discharges or…
- Conditions
- Autism Spectrum Disorder, EEG With Periodic Abnormalities, Epilepsy, Neurodevelopmental Disorders
- Trial name
- tPBM (NCT06352372)
- Testing
- noninvasively delivered near infra-red (NIR) light - transcranial Photobiomodulation (tPBM)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Richard Frye
Difference in Regional Brain Activity
Backward Masking Tasks to Decipher Impaired Input-Output Connections in MS @7T
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system. People with MS frequently suffer from cognitive and visual impairment.
- Trial name
- BIO7 (NCT05377671)
- Testing
- IRM multimodale a ultra-haute camp
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Cerebral Palsy, Autonomic Nerveus System
BioFeedBack Breathing Training Influence Cardiac Autonomic Nervous System in Children With Cerebral-Palsy.
The effect of breathing biofeedback training to influence the function of the cardiac autonomic nervous system at rest and in activity in children with cerebral palsy.
- Trial name
- NCT01872507
- Testing
- Biofeedback training
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Aphasia
Analysis of Brain Activity to Uncover Brain-behavior Relationships Related to Therapy Outcomes in Aphasia
Aphasia is a loss of language due to stroke or other brain injury. Word-finding in conversation is a universal and persistent difficulty in aphasia.
- Trial name
- NCT03550092
- Testing
- Abstract Semantic Association Network Training (AbSANT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Penn State University
Parkinson's Disease (PD)
An Observational Study of Subcutaneous Infusion of ABBV-951 to Assess Change in Disease Activity and Adverse Events In Adult Japanese Participants With Advanced Parkinson's Disease
Parkinson's disease (PD) is a neurological condition, which affects the brain. Some symptoms of PD are tremors, stiffness, and slowness of movement.
- Trial name
- NCT05916157
- Where
- 17 sites in Japan
- Volunteers
- 250 people
- Sponsor
- AbbVie
Alzheimer's Disease
Efficacy and Safety Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease
The primary purpose of this study is to determine whether ELND005 is effective in treating symptoms of agitation and aggression in patients with Alzheimer's disease
- Trial name
- NCT01735630
- Testing
- ELND005
- Where
- 70 sites in United States, Canada and 2 more
- Volunteers
- 350 people
- Sponsor
- OPKO Health, Inc.
Alzheimer's Disease
Memantine on Aggression and Agitation of Alzheimer's Disease (AD)
Alzheimer's disease (AD), is associated with behavioral disturbances in approximately 50% of AD patients in Beijing. Agitation, and aggression specifically, is considered the most serious noncognitive symptom experienced in…
- Trial name
- NCT00703430
- Testing
- Memantine
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University
Stroke, Motor Activity
Observational Study of Ischaemic Stroke
The rationale for this study is to facilitate future Phase II/III clinical trials and improve outcome for patients suffering residual disability after an ischaemic stroke.
- Trial name
- OSIS (NCT01859572)
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- ReNeuron Limited
Parkinson Disease
Education for Adapted Physical Activity in Parkinson's Disease
Parkinson's disease is a progressive disorders characterized by motor and non-motor symptoms. Actual medical treatments are symptomatic and have little efficacy on late stage axial motor symptoms.
- Trial name
- ACTIF-PARK (NCT04340492)
- Testing
- Education to Adapted Physical Activity, Standard care
- Where
- France
- Volunteers
- 89 people
- Sponsor
- University Hospital, Lille
Atrial Fibrillation, Stroke
Hemostatic Activity Following LAAO
The primary objective of this study is to prospectively investigate hemostatic activity following transcatheter left atrial appendage occlusion (LAAO).
- Trial name
- NCT05011981
- Testing
- Left Atrial Appendage Occlusion
- Where
- Denmark
- Volunteers
- 135 people
- Sponsor
- University of Aarhus
Dementia
Mediterranean Diet, Exercise and Dementia Risk in UK Adults
In cohort studies, a Mediterranean Dietary Pattern (MDP) has been consistently associated with reduced dementia incidence. The efficacy of a MDP to prevent dementia has never been directly demonstrated by RCTs, with existing…
- Trial name
- MedEx-UK (NCT03673722)
- Testing
- Foods consistent with a MDP, Physical Activity, Control
- Where
- 3 sites in United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
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