Clinical trials: Brain Age
Cognitive Impairment
The Mental Activity and eXercise Trial for Seniors
The primary objective of this study is to conduct a randomized, controlled trial to determine whether engaging in mental activity or exercise, either alone or in combination, improves cognitive function in non-demented, inactive…
- Trial name
- MAX (NCT00522899)
- Testing
- Group 1, Group 2, Group 3
- Where
- 2 sites in United States
- Volunteers
- 126 people
- Sponsor
- University of California, San Francisco
Old Age, Depression
Accelerated Deep TMS in the Elderly Depressed: A Brain Imaging Approach
With a growing number of elderly persons, geriatric depression - associated with important morbidity and mortality- is becoming a significant health problem.
- Trial name
- NCT03978182
- Testing
- accelerated deep rTMS
- Sponsor
- Universitair Ziekenhuis Brussel
Age Problem, Disability
China Healthy Aging Cohort Study
This is a community-based prospective cohort study in China. The study has been initialized in 2024 and included older residents.
- Conditions
- Age Problem, Disability, Dementia, Death
- Trial name
- China-Ageing (NCT06472674)
- Testing
- No intervention
- Where
- China
- Volunteers
- 6,780 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Nursing Homes, Aged
BABEL Advance Care Planning in Long-term Care
1.0 SUMMARY Most Canadian nursing home (NH) residents are elderly and frail, have multiple chronic health conditions and impairments, and have dementia.
- Conditions
- Nursing Homes, Aged, Frail Elderly Syndrome, Dementia
- Trial name
- BABEL (NCT03649191)
- Testing
- The BABEL Approach to Advance Care Planning in Nursing Homes, Control group Advance Care Planning
- Where
- 3 sites in Canada
- Volunteers
- 713 people
- Sponsor
- University of Manitoba
Health Behavior, Aging
B-Fit Intervention to Improve Brain Health
An accumulating body of research indicates that activities such as exercise, active cognitive and social engagement, good sleep hygiene, stress reduction and proper nutrition are associated with the maintenance of cognitive…
- Trial name
- B-Fit (NCT03454074)
- Testing
- Problem-solving, Education
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington State University
Healthy
Women's Health Initiative Study of Cognitive Aging
The Women's Health Initiative Study of Cognitive Aging (WHISCA) is a two-armed, randomized, placebo controlled, clinical trial designed to assess the efficacy of postmenopausal hormone therapy (HT) on age related changes in…
- Trial name
- WHISCA (NCT00631332)
- Where
- United States
- Volunteers
- 2,303 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Alzheimer's Disease, Mild Cognitive Impairment
Effectiveness of a Brain-Computer Interface Based System for Cognitive Enhancement in the Normal Elderly
The primary objective is to examine the efficacy of 8-weeks of a locally developed brain-computer interface based system (BrainpalTM)intervention for improving attention and memory in normal elderly.
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Age-Related Cognitive Decline, Dementia
- Trial name
- 3ECog (NCT01661894)
- Testing
- BrainPalTM
- Where
- Singapore
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Intraventricular Hemorrhage, Premature Birth
Intranasal Fresh Mother's Own Milk to Prevent Intraventricular Hemorrhage in Extremely Preterm Infants
Babies born very prematurely are at risk of intraventricular hemorrhage (IVH), which is bleeding in or around the fluid-filled spaces of the brain. Most IVH occurs during the first week after birth.
- Trial name
- iF-MOM-IVH (NCT07812922)
- Testing
- Intranasal Fresh Mother's Own Milk (iF-MOM)
- Volunteers
- 67 people
- Sponsor
- University of Manitoba
Cerebral Palsy
Association of a HABIT-ILE Course and a Home Programme on the Bimanual Performance of Children With Cerebral Palsy
This non-inferiority, mixed-methods, multicentre randomised controlled trial will compare the effects of functional changes and families' resources at 3 months of the PARTNER programme (35h HABIT-ILE + 15h home programme) with…
- Trial name
- PARTNERSHIP (NCT06963151)
- Testing
- Behavioral: Hand-Arm Bimanual Intensive Therapy Including Lower Extremities
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Fondation Ildys
Progesterone, Estrogens
Neural Changes in the Aging Auditory System
The purpose of this study was to determine the effects of hormone replacement therapy (HRT) on hearing in post-menopausal women.
- Conditions
- Progesterone, Estrogens, Hearing, Psychoacoustics
- Trial name
- NCT00264407
- Testing
- Hormone Replacement Therapy - HRT
- Where
- 2 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Unilateral Cerebral Palsy, School Readiness
School Readiness in Preschool-Aged Children With Cerebral Palsy
The goal of this feasibility and proof of concept study is to learn about the feasibility, acceptability, and impact of a school readiness program for preschool-aged children with unilateral cerebral palsy.
- Trial name
- NCT06083220
- Testing
- Smart Start - School Readiness Program
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Epilepsy
Pharmacokinetic Study of Levetiracetam in Epileptic Pediatric Subjects Ranging in Age From 1 Month to Less Than 4 Years Old
The primary purpose of this study was to document the pharmacokinetic parameters of both levetiracetam and its metabolite, ucb L057, after a single dose of 20 mg/kg of levetiracetam in epileptic pediatric subjects, aged 1 month…
- Trial name
- NCT00544050
- Testing
- Levetiracetam
- Volunteers
- 13 people
- Sponsor
- UCB Pharma
Migraine
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine
The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.
- Trial name
- PIONEER-PEDS1 (NCT04396236)
- Testing
- Lasmiditan
- Where
- 152 sites in United States, Belgium and 13 more
- Volunteers
- 847 people
- Sponsor
- Eli Lilly and Company
Auditory Processing Disorder
Effects of Remote Microphone Hearing Aids on Children With Auditory Processing Disorder
Auditory Processing Disorder (APD) is a disorder where the functions of the ear are normal, but the person has difficulty identifying or discriminating sounds and experiences listening difficulties in noise.
- Trial name
- NCT02353091
- Testing
- Remote Microphone Hearing Aids
- Volunteers
- 26 people
- Sponsor
- University College, London
Migraine
A Trial to Test if Fremanezumab is Effective in Preventing Migraine in Children and Adolescents
The primary objective of the study is to evaluate the long-term safety and tolerability of subcutaneous fremanezumab in the preventive treatment of migraine in pediatric participants 6 to 17 years of age (inclusive at enrollment…
- Trial name
- NCT04530110
- Testing
- Fremanezumab
- Where
- 70 sites in United States, Canada and 7 more
- Volunteers
- 499 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D LLC
Preterm Birth
Cerebral Magnetic Resonance Spectroscopy at Term Corrected Age and Dysexecutive Syndrome in Very Preterm Children at 5.5-years-old
Background: Compared to term-born peers, very preterm children generally perform poorly in executive functions, with a significant impact on learning at school and quality of life.
- Trial name
- Spectro5-5 (NCT06055062)
- Volunteers
- 39 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Growth Hormone Deficiency, Idiopathic Short Stature
Long-term Safety and Effectiveness of Growtropin®-II Treatment in Children With Short Stature
This study evaluates long-term safety and effectiveness of Growtropin®-II treatment in children with short stature.
- Conditions
- Growth Hormone Deficiency, Idiopathic Short Stature, Turner Syndrome, Small for Gestational Age
- Trial name
- NCT04798690
- Where
- South Korea
- Volunteers
- 5,000 people
- Sponsor
- Dong-A ST Co., Ltd.
Sleep Disorder, Insomnia
Brain Gym Therapy on Quality of Sleep Among Elderly People
This clinical trial aims to evaluate the impact of Brain Gym Therapy on the quality of sleep among elderly individuals attending healthcare facilities.
- Conditions
- Sleep Disorder, Insomnia, Cognitive Function Abnormal, Old Age; Debility
- Trial name
- BG/E (NCT06553690)
- Testing
- Brain Gym Therapy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infant, Newborn, Infant, Low Birth Weight
Cerebral Function Monitoring in Premature Infants
This observational study tests the feasibility of enrolling subjects and obtaining an amplitude-integrated electroencephalogram (aEEG) within the first 72 hours of life, a second aEEG recording between 72-168 hours of life, and…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- NCT00873847
- Where
- 8 sites in United States
- Volunteers
- 102 people
- Sponsor
- NICHD Neonatal Research Network
Aging, Age-Related Memory Disorders
Effects of Blueberry on Cognition and Mobility in Older Adults
This study is being conducted to assess the effect of dietary blueberry supplementation on cognition and mobility in older adults.
- Trial name
- NCT01888848
- Testing
- Freeze-dried Blueberry
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- USDA Human Nutrition Research Center on Aging