Clinical trials: Brain Connectivity
Brain Network Connectivity, Postoperative Delirium
The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma
Perioperative anesthesia can affect postoperative cognitive function. In our previous study, intraoperative dexmedetomidine (Dex) infusion reduced the incidence of delirium within the first 5 days after brain tumor.
- Conditions
- Brain Network Connectivity, Postoperative Delirium, Dexmedetomidine, Propofol
- Trial name
- NCT06138340
- Testing
- Dexmedetomidine, Propofol, Remimazolam Injection
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Tiantan Hospital
Epileptic Syndromes
Electro-clinical Features and Functional Connectivity Analysis in SYN1 Gene Mutation-related Epilepsy
SYN1 gene mutation is an X-linked gene mutation that causes numerous pathological manifestations such as seizures and neurodevelopmental disorders.
- Trial name
- NCT06222840
- Testing
- Electro-clinical analysis of epileptic seizures, Electro-encephalographic cases, Clinical datas analysis
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Rolandic Epilepsy, Nocturnal Frontal Lobe Epilepsy
The Rolandic Epilepsy/ESES/Landau-Kleffner Syndrome and Correlation With Language Impairment Study
In clinical practice language impairment is frequently reported in association with nocturnal epileptiform activity. There is a spectrum of epileptic conditions that are characterized by nocturnal epileptiform activity.
- Conditions
- Rolandic Epilepsy, Nocturnal Frontal Lobe Epilepsy, Landau-Kleffner Syndrome, Electrical Status Epilepticus During Slow Wave Sleep
- Trial name
- REL (NCT01335425)
- Where
- Netherlands
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Stroke
Neurofeedback Training of Alpha-band Coherence After Stroke
Background: The technology of brain-computer interfaces (BCI) enables the monitoring of brain activity and the generation of a real-time output about specific changes in activity patterns.
- Trial name
- NCT02223910
- Testing
- Neurofeedback training of functional connectivity
- Where
- Switzerland
- Volunteers
- 13 people
- Sponsor
- University Hospital, Geneva
Low Back Pain, Healthy
Brain Connectivity and Perceptive Surfaces in Chronic Low Back Pain (SUPER-RMNf)
Rationale: Chronic Low Back Pain (CLBP) is often associated with "cortical reorganization," where the brain's map of the back becomes less precise.
- Trial name
- NCT07568353
- Testing
- Perceptive Surface (SU-PER mat)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Obesity, Eating Behaviour
The Effect of Neurofeedback on Eating Behaviour
Neuroimaging is becoming increasingly common to investigate the neural networks underlying eating behaviour and food preference in normal-weight and obese humans.
- Trial name
- NCT02148770
- Testing
- Neurofeedback
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Chronic Musculoskeletal Disease
Acceptance and Commitment Therapy, a Mindfulness-Based Approach for Treatment of Chronic Musculoskeletal Pain
Acceptance and Commitment Therapy (ACT) has been recognized as an effective, non-pharmacologic treatment for a variety of CP conditions. However, little is known about the neurologic mechanisms underlying ACT.
- Trial name
- NCT04502992
- Testing
- Acceptance and Committment Therapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of New Hampshire
Healthy
Effects of Oxytocin on the Functional Architecture of the Brain Before and After Prolonged Naturalistic Fear Induction
The main aim of the pharmacological resting-state fMRI study is to investigate the modulatory effects of intranasal Oxytocin (24IU) on task and intrinsic functional connectivity before and after prolonged exposure to naturalistic…
- Trial name
- NCT05896553
- Testing
- intranasal Oxytocin(24IU)
- Where
- China
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
MRI, Functional, Carotid Artery Stenosis
Cognitive Function and Brain Connectivity in CAS Patients:a Rs-fMRI Study
This is a prospective study aimed to explore the changes of cognitive function after surgery for CAS and the correlation with brain connectivity, in order to look for the clinical biomarkers to predict the carotid stent…
- Trial name
- NCT05292729
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Movement Disorder, Focal Dystonia
Movement-Related Brain Networks Involved in Hand Dystonia
This study will use various methods to measure the activity of the motor cortex (the part of the brain that controls movements) in order to learn more about focal hand dystonia.
- Trial name
- NCT00137384
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Small Vessel Disease, Cognitive Impairment
Remote Ischemic Conditioning for Cognitive Impairment in Cerebral Small Vessel Disease
This randomized, double-blind, sham-controlled trial aims to evaluate the effect of remote ischemic conditioning (RIC) on cognitive function in patients with cerebral small vessel disease-related mild cognitive impairment.
- Trial name
- RIC-CSVD (NCT07317557)
- Testing
- Remote ischemic conditioning using IPC-906 device
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Jiangsu Province Nanjing Brain Hospital
Idiopathic Generalized Epilepsy
Study of Attentional Disorders in Patients Suffering From Idiopathic Generalized Epilepsy.
Attentional disorders have been reported in neuropsychological studies evaluating patients suffering from generalized idiopathic epilepsy, but the data are disparate (in terms of test protocol).
- Trial name
- ATTENTIONEPIG (NCT05530109)
- Testing
- Neuropsychological screening and high resolution EEG recording
- Where
- France
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Cocaine Use Disorder (CUD)
Examination of Transcranial Focused Ultrasound on Brain Activity in Adults With Cocaine Use Disorder
The investigators aim to examine the effect of transcranial focused ultrasound (tFUS) on brain activity and cocaine craving in adults with cocaine use disorder.
- Trial name
- NCT07852923
- Testing
- tFUS
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Mary Phillips, MD MD (Cantab)
Stroke
Recovery Prediction of Motor Function Using Neuroimaging Techniques in Subacute Stroke Patients
Prediction of recovery from stroke can assist in the planning of impairment-focused rehabilitation. To achieve better prediction for clinical purposes, this study investigated a new prediction model with low inter-individual…
- Trial name
- NCT03365596
- Testing
- Conventional therapy
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Alzheimer's Disease
The Role of Mid-Life Adiposity in Functional Brain Connectivity
The purpose of the study is to use functional MRI (fMRI) to measure brain connectivity in middle-aged individuals with different levels of body fat.
- Trial name
- NCT01777789
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin