Clinical trials: Brain Fog, open to volunteers
Intensive Care Unit
Impact of an Alarm Management Protocol on Noise Pollution and Patient Safety in Intensive Care Units
Resuscitation patients are monitored for various physiological parameters. When these parameters exceed abnormal thresholds, an audible alarm is triggered.
- Trial name
- REALARM (NCT06175091)
- Testing
- alarm management left to the discretion of the nurse, restrictive alarm use strategy
- Where
- France
- Volunteers
- 514 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Postural Orthostatic Tachycardia Syndrome (POTS), Dysautonomia
Guanfacine and Cromolyn Sodium for POTS: The DBPOTS Trial
The goal of this clinical trial is to learn whether guanfacine or cromolyn sodium can improve symptoms and physical functioning in adults with Postural Orthostatic Tachycardia Syndrome (POTS).
- Conditions
- Postural Orthostatic Tachycardia Syndrome (POTS), Dysautonomia, Orthostatic Intolerance, Autonomic Nervous System Diseases
- Trial name
- DBPOTS (NCT07757555)
- Testing
- Guanfacine (GFC), Cromolyn Sodium
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Johns Hopkins University
Vitamin b12, Supplementation During Endurance Performance
Effects of Vitamin B12 and Natural Orange Extract, and Their Combination on Physical and Mental Performance
The aim of this study was to determine the effects of a new formulation of vitamin B12, natural orange extract, and their combination on physical and mental performance.
- Conditions
- Vitamin b12, Supplementation During Endurance Performance, Flavonoids, Mental Fatigue
- Trial name
- MECHEPS (NCT07341789)
- Testing
- Vitamin B 12, Natural orange extract, Vitamina B12 + natural orange extract
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Post-Treatment Lyme Disease
Transcranial Direct Current Stimulation for Post Treatment Lyme Disease
The primary purpose of this pilot study is to investigate a novel approach to the treatment of cognitive symptoms that persist despite prior antibiotic treatment for Lyme disease (Post treatment Lyme Disease or PTLD).
- Trial name
- NCT06915324
- Testing
- Transcranial Direct Current Stimulation (tDCS), Cognitive training
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- Columbia University
Breast Cancer Survivor, Cancer Related Cognitive Difficulties
The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors
The investigators are interested in finding out how Prolonged Nightly Fasting (PNF) and/or health education may impact health and cancer recovery for breast cancer patients and survivors.
- Conditions
- Breast Cancer Survivor, Cancer Related Cognitive Difficulties, Sleep, Quality of Life
- Trial name
- RESTORE (NCT06938555)
- Testing
- Prolonged Nightly Fasting, Health Education Videos
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Arizona State University
Balance
the Impact of Physical and Mental Fatigue on Balance
Mental and physical Fatigue and overall fatigue will be collected based on Fatigue assessment scale while balance data will be obtained by recording mobile sensors in X, Y and Z directions when mobile placed on COG of the…
- Trial name
- NCT06716697
- Testing
- physical and mental fatigue
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Parkinson Disease, Freezing of Gait
Application of Thoracic Epidural SCS for Managing FOG in Patients With Advanced Parkinson's Disease
Spinal cord stimulation (SCS) has proven to be effective for pain that is unresponsive to medication. This technique involves an anesthesiologist or a neurosurgeon placing stimulation electrodes at the thoracic vertebrae to…
- Conditions
- Parkinson Disease, Freezing of Gait, Spinal Cord Stimulation
- Trial name
- NCT06630702
- Testing
- SCS electrode stimulation 1, SCS electrode stimulation 2, SCS electrode stimulation 3
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- National Taiwan University Hospital
ME/CFS, ME/CFS Following EBV-associated Infectious Mononucleosis
ME/CFS Brain Fog: Cognitive Rehabilitation Trial
The purpose of this study is to compare two approaches to cognitive rehabilitation in adults with post-viral cognitive syndrome, which resulted in brain fog.
- Conditions
- ME/CFS, ME/CFS Following EBV-associated Infectious Mononucleosis, ME/CFS Following COVID-19, Chronic Fatigue
- Trial name
- NCT07523113
- Testing
- Processing Speed Training, In-session Instrumental Activities of Daily Living Training, Transfer Package
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Burnout, Caregiver, Compassion Fatigue
Exercise for Oncology Care Professionals
The goal of this preference-based pilot study will be to assess the feasibility and acceptability, and impact of a 12-week exercise intervention on oncology care provider burnout.
- Trial name
- C4C+ (NCT05884073)
- Testing
- Circuit-based Resistance Training, Nature-based Walking
- Where
- 2 sites in Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Melanie Keats
Menopause, Perimenopause
Effects of Hemp-Derived Cannabinoids on Menopause Symptoms
The purpose of the study is to examine the impact of hemp-derived minor cannabinoids on symptoms of menopause/perimenopause.
- Trial name
- NCT07393672
- Testing
- Hemp-derived cannabinoids
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Washington State University
Burnout, Secondary Trauma
PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R33 Phase Clinical Trial)
The investigators propose to test the effectiveness of PATH (Peer Advanced Training for total Health) as an educational workforce intervention for improving peer recovery support specialists' (PRSS) overdose prevention (OP)…
- Conditions
- Burnout, Secondary Trauma, Compassion Fatigue, Opioid Use Disorder
- Trial name
- NCT07886944
- Testing
- PATH (Peer Advanced Training for total Health)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Chestnut Health Systems
Post-Acute Sequelae of SARS-CoV-2 Infection, Long COVID
Observational Study of Intranasal IVIG in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Patients Undergoing Medical Tourism
This observational study is being conducted by Healing Hope International to collect real-world data on an emerging treatment approach for Long COVID in patients with immunodeficiency.
- Conditions
- Post-Acute Sequelae of SARS-CoV-2 Infection, Long COVID, Long COVID Fatigue, Long COVID Syndrome
- Trial name
- IVIG-LC (NCT06992401)
- Volunteers
- 50 people
- Sponsor
- Tamara C Tamas
Multiple Sclerosis
Virtual Reality - Gamma Sensory Stimulation for Improving Fatigue in People With Multiple Sclerosis
This is a double-blind, parallel, randomized, sham-controlled pilot study evaluating the safety, feasibility, and efficacy of Gamma Sensory Stimulation (GSS) delivered via a Virtual Reality (VR) headset in individuals with…
- Trial name
- VR-GSS (NCT07310862)
- Testing
- Virtual Reality Gamma Sensory Stimulation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Clarity Health Technologies, Inc
Obstructive Sleep Apnea
Brain Fog in Sleep Apnea
Objective: This observational, cross-sectional pilot study aims to assess "Brain Fog" (cognitive symptoms impacting memory, attention, and concentration) in severe Obstructive Sleep Apnea (OSA) patients.
- Trial name
- BF -OSA (NCT06664450)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Registered Nurses, Compassion Fatigue
Intervention Study on Compassion Fatigue and Satisfaction in Omani Nurses
The purpose of this study is to assess the level of compassion fatigue and compassion satisfaction among nurses working at Ministry of Health hospitals.
- Conditions
- Registered Nurses, Compassion Fatigue, Occupational Stress, Mental Health
- Trial name
- NCT07100717
- Testing
- 2-days workshop and self-mindfulness practices
- Where
- Oman
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oman Ministry of Health
Maximum Force, Strength Endurance
The Effects of Caffeine and Vitamin C on Maximum Strength and Strength Endurance in Adolescents With Mild Mental Fatigue
Objective To investigate the independent and combined effects of caffeine and vitamin C on maximal strength and strength endurance in female adolescents with mild mental fatigue.
- Conditions
- Maximum Force, Strength Endurance, Mental Fatigue
- Trial name
- NCT07726745
- Testing
- 1RM squats and bench presses; repetitions at 65% of 1RM for squats and bench presses
- Volunteers
- 40 people
- Sponsor
- Yunliang Zhang
Alert Fatigue, Health Personnel
Intervention Program for Alarm Fatigue in NICU Nurses Based on ABC-X Model
Monitors in newborn intensive care (NICU) help keep babies safe, but the constant beeping can overwhelm nurses. This 'alarm fatigue' makes it harder for nurses to identify real emergencies, stresses them out, and can impact…
- Trial name
- NCT07025863
- Testing
- Alarm Fatigue Intervention Program
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Guizhou Medical University
Alarm Fatigue, Perioperative
Intraoperative Cognitive Load in Anesthesia Nurses Across Anesthetic Phases
The goal of this observational study is to measure the cognitive load (mental effort) of anesthesia nurses during real surgical procedures at Hospital Clínic de Barcelona, Spain.
- Conditions
- Alarm Fatigue, Perioperative, Patient Safety, Cognitive Load
- Trial name
- ENCOPER (NCT07568158)
- Testing
- NASA Task Load Index (NASA-TLX)
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Occupational Stress and Mental Health in Clinical Nurses, Burnout
On-Demand AI Support Via LINE-Based GPT Assistant to Improve Emotional Resilience and Reduce Burnout Among Clinical Nurses
Clinical nurses are frequently exposed to high emotional demands due to heavy workloads, time pressure, patient suffering, and the interpersonal complexity of clinical care.
- Conditions
- Occupational Stress and Mental Health in Clinical Nurses, Burnout, Compassion Fatigue, Psychological Resilience
- Trial name
- Nurse-AI-CARE (NCT07380685)
- Testing
- Interactive LINE GPT Emotional Support, Static Supportive Messages
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Fibromyalgia Syndrome, Fibromyalgia
Pain & Reward Neuromodulation of CNS Circuits
This pilot feasibility study aims to evaluate transcranial magnetic stimulation (TMS) targeting the prefrontal cortex in patients with fibromyalgia syndrome (FMS).
- Conditions
- Fibromyalgia Syndrome, Fibromyalgia, Chronic Pain and Fatigue
- Trial name
- PRANCIR (NCT07525063)
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Duke University