Clinical trials: Brain Health Activities
Stroke, Non-communicable Disease
Make My Day - a Stroke Prevention Program
The purpose of this study is to evaluate the effects of a person-centered stroke prevention program implemented in primary healthcare.
- Trial name
- NCT05279508
- Testing
- Make My Day - stroke prevention program
- Where
- Sweden
- Volunteers
- 122 people
- Sponsor
- Karolinska Institutet
Healthy Individuals (Controls), Parkinson Disease
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.
- Conditions
- Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
- Trial name
- Allena-mente (NCT07066137)
- Testing
- CAREN, Control group
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Elderly People
Improving the Quality of Life of Elderly Individuals Living in Nursing Homes
The development of physical activity (PA) and exercise habits improves strength, flexibility, balance and coordination, activities such as walking, sleep quality and cognitive status in elderly people and supports their…
- Trial name
- NCT06520956
- Testing
- Video based exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Galata University
MCI, Mild Cognitive Impairment
The Interactive Physical and Cognitive Exercise System (v3) for Mild Cognitive Impairment (MCI)
The primary purpose of this study is to attempt to replicate and extend promising pilot findings regarding the cognitive benefits of in-home neuro-exergaming with iPACES (interactive Physical and Cognitive Exercise System v3) for…
- Conditions
- MCI, Mild Cognitive Impairment, Alzheimer Disease, Dementia
- Trial name
- iPACES (NCT05009524)
- Testing
- iPACES (interactive Physical and Cognitive Exercise System), PACE (Physical and Cognitive Exercise)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- iPACES LLC
Relapsing-Remitting Multiple Sclerosis
Behavior and Activity Monitoring in MS
The investigators propose to conduct a randomized 6-month intervention study comparing cognitive functioning in individuals with relapsing-remitting multiple sclerosis assigned to either a physical activity or an active…
- Trial name
- NCT03244696
- Testing
- Step Tracking, Water Tracking
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Ohio State University
Creatine, Exercise
Creatine and Resistance Training in Older Adults With Mild Cognitive Impairment
The goal of this 26-week trial is to learn if creatine supplementation and resistance training (i.e., weightlifting; exercise that increases muscle mass), alone and together, impact cognition, brain health, and physical function…
- Conditions
- Creatine, Exercise, Mild Cognitive Impairment (MCI)
- Trial name
- NCT06948149
- Testing
- Creatine monohydrate, Resistance training
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Western University, Canada
Stroke
Thriving, Activity and Social Participation After Stroke
The aim of the study is to evaluate the effect of a group intervention programme for community dwelling elders with stroke or TIA.The intervention is inspired by a Lifestyle Redesign method developed in the USA.
- Trial name
- NCT00495248
- Testing
- Group intervention inspired by Lifestyle Redesign
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Ullevaal University Hospital
Patient Compliance
Cognitive Regulation Training and Exercise Trial
The purpose of this double-blinded, randomized controlled study is to compare CORTEX (Cognitive Regulation Training and Exercise), a multi-faceted, center- and home-delivered- general and exercise-specific-active and traditional…
- Trial name
- CORTEX-II (NCT03124667)
- Testing
- Games, Videos
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Lifestyle (Sedentary Behavior and Physical Activity), Lifestyle Intervention
Healthy Eating and Active Living (HEAL), Exploring Feasibility of a Lifestyle Intervention
Lifestyle interventions combining nutrition, physical activity, and behavioral strategies are increasingly recognized for improving metabolic and psychological health, yet their translation into real-world settings remains…
- Conditions
- Lifestyle (Sedentary Behavior and Physical Activity), Lifestyle Intervention, Lifestyle Modification
- Trial name
- HEAL (NCT07662499)
- Testing
- Multimodal lifestyle intervention (HEAL program)
- Where
- United Arab Emirates
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- New York University Abu Dhabi
Parkinson's Disease
Utilization of Aerobic Exercise to Maintain Neurologic Health
A promising approach to combat the protein aggregation, oxidative stress, and neuroinflammation occurring with PD is consistent aerobic exercise. Dr.
- Trial name
- NCT07882446
- Testing
- Aerobic Exercise
- Volunteers
- 100 people
- Sponsor
- The Cleveland Clinic
Parkinson Disease, Prodromal Stage
Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands
The goal of this clinical trial is to investigate the feasibility if a remotely administered smartphone app can increase the volume and intensity of physical activity in daily life in patients with isolated Rapid Eye Movement…
- Conditions
- Parkinson Disease, Prodromal Stage, Neurodegenerative Diseases, Parkinsonian Disorders
- Trial name
- Slow-SPEED-NL (NCT06193252)
- Testing
- Increase of physical activity volume and intensity with the use of a motivational smartphone application
- Where
- Netherlands
- Volunteers
- 110 people
- Sponsor
- Radboud University Medical Center
Older Adults (50-90 Years), Cognition
Let's Increase Fuerza (Strength) Through Exercise and Diet
The purpose of the study is to conduct a 6-month randomized controlled trial among Latinos ages 50+ at risk for cognitive decline and compare the efficacy of a remote-delivered, culturally tailored Latin dance program and…
- Conditions
- Older Adults (50-90 Years), Cognition, Physical Activity
- Trial name
- LIFTED (NCT06884501)
- Testing
- Latin dance, MIND diet, and Strength training, Latin dance and MIND Diet
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Hiv
Action for Brain Health Now: Ready, Set, Go
HIV (human immunodeficiency virus) can have subtle but important effects on the brain, leading to difficulties in memory, concentration, or problem solving.
- Trial name
- NCT04345484
- Testing
- Goal-management training, Control
- Where
- 4 sites in Canada
- Volunteers
- 100 people
- Sponsor
- McGill University
Parkinson Disease, Prodromal Stage
Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage
The goal of this clinical trial is two-fold. First to investigate the feasibility of whether a remotely administered smartphone app can increase the volume and intensity of physical activity in daily life in individuals with a…
- Conditions
- Parkinson Disease, Prodromal Stage, Neurodegenerative Diseases, Basal Ganglia Diseases
- Trial name
- Slow-SPEED (NCT06993142)
- Testing
- Increase of physical activity volume and intensity with the use of a motivational smartphone application
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 600 people
- Sponsor
- Radboud University Medical Center
Physical Disability, Cognitive Impairment
Improving Aging in Place in Subsidized Housing
This pilot study will evaluate the feasibility and preliminary effectiveness of an adapted version of the Function Focused Care intervention, delivered by telephone, for improving aging in place for older adults living in…
- Conditions
- Physical Disability, Cognitive Impairment, Physical Activity
- Trial name
- NCT04212442
- Testing
- Independent Living Program for Affordable Housing.
- Where
- 13 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Dementia, Caregiver
A Robot-assisted Tailored Activity Programme for People With Dementia and Their Caregivers
To assess the feasibility and preliminary efficacy of the tailored activity programme on improving the physical inactivity of the caregiving dyads.
- Conditions
- Dementia, Caregiver, Physical Activity, Psychological Well Being
- Trial name
- NCT07239869
- Testing
- Intervention, Control
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity
Where Wild Things Grow: Nature- and Activity-based Group Interventions for Neurodivergent Children and Youth
The goal of this action research project is to develop and implement nature- and activity-based group interventions across health care, school and leisure settings in Southern Norway.
- Conditions
- Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity, Autism, Tourette Syndrome
- Trial name
- NCT07203469
- Testing
- Universal approach, Selective approach, Outdoor therapy
- Where
- 2 sites in Norway
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Cerebral Palsy
Telehealth Virtual Reality Gaming on Cardiometabolic Health Among Youth With Cerebral Palsy
The primary purpose of this study is to examine the preliminary efficacy of 12-weeks of home-based exercise using consumer available virtual reality gaming technology, compared with a 12 week wait-list control group.
- Trial name
- NCT05336227
- Testing
- Virtual Reality Exergaming
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Exercise, Children
Long-term Exercise Effects from Robotic Walking
The vision of the Long-term Exercise Effects from Robotic Walking (LEER) research program is to develop optimal, individualized exercise strategies that would in turn enhance the health and well-being of non-ambulatory children…
- Conditions
- Exercise, Children, Cerebral Palsy
- Trial name
- LEER (NCT04307602)
- Testing
- Exercise - High Intensity Interval Training (HIIT), Exercise - Submaximal Steady State Training (SST)
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lund University
Cognitive Impairment, Mild, Cognitive Decline
Efficacy of a Multimodal Brain Health Intervention for Older African Americans
This study tests the feasibility, acceptability, and efficacy of a multimodal intervention (walking, social engagement, and reminiscence), including the use of wearable digital biomarkers, for cognitively healthy and mildly…
- Trial name
- SHARP (NCT04863378)
- Testing
- Walking conversational reminiscence
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University