Clinical trials: Brain Infarction, open to volunteers
Diabetes Mellitus, Type 2, Cardiovascular Diseases
The Cardio-Metabolic Clinic
This study aims to investigate whether a Cardio-Metabolic Clinic can protect the cardiovascular health of patients with both diabetes and cardiovascular disease.
- Trial name
- ProtecT-2-D (NCT06203860)
- Testing
- Cardio-Metabolic Clinic
- Where
- Denmark
- Volunteers
- 1,600 people
- Sponsor
- Odense University Hospital
High Resolution Vessel Wall Imaging, Recurrent Stroke
Plaque Characteristics Predict Recurrent Stroke in MCA Stroke Patients
The epidemiology of TOAST classification in Asian patients seems to differ due to the higher rates of large-artery atherosclerosis.
- Conditions
- High Resolution Vessel Wall Imaging, Recurrent Stroke, Stroke, Mechanism, Atheroscleroses, Intracranial
- Trial name
- NCT06404242
- Where
- Vietnam
- Volunteers
- 75 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Silent Stroke, Silent Cerebral Infarct
Prevalence of Attributable Etiology and Modifiable Stroke Risk Factors in Patients With Covert Brain Infarctions
The CBI registry is a prospective, interdisciplinary, multimodal observational registry of patients with covert brain infarction.
- Conditions
- Silent Stroke, Silent Cerebral Infarct, Covert Brain Infarct, Covert Brain Infarction
- Trial name
- CBI-Registry (NCT05685069)
- Where
- 2 sites in France, Switzerland
- Volunteers
- 230 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Subarachnoid Hemorrhage, Aneurysmal, Cerebral Injury
Effect of Xenon on Brain Injury After Aneurysmal Subarachnoid Hemorrhage
An investigator-initiated clinical drug study Main Objective: To explore neuroprotective properties of xenon in patients after aneurysmal subarachnoid hemorrhage (SAH).
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Cerebral Injury, Cerebral Ischemia, Cerebral Infarction
- Trial name
- Xe-SAH (NCT04696523)
- Testing
- Xenon, air/oxygen
- Where
- 7 sites in Finland, Sweden
- Volunteers
- 160 people
- Sponsor
- Turku University Hospital
Brainstem Stroke, ALS
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)
People with brainstem stroke, advanced amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), or other disorders can become unable to move or speak despite being awake and alert.
- Conditions
- Brainstem Stroke, ALS, Tetraplegia, Spinal Cord Injuries
- Trial name
- BG-Tablet-01 (NCT06511934)
- Testing
- BrainGate Neural Interface System
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Leigh R. Hochberg, MD, PhD.
Sturge - Weber Syndrome (SWS)
Developing a Tailored Neuropsychological Rehabilitation for Sturge-Weber Syndrome
The goal of this observational study is to learn about the neuropsychological profile of Sturge-Weber Syndrome (SWS) in children and adults with this rare neurocutaneous condition.
- Trial name
- NPS-SWS (NCT07655492)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
Ischemia, Cerebrovascular Ischemia
LA Improves the Prognosis of Patients With ICVD
Ischemic cerebrovascular disease will cause serious harm to the life and safety of patients, and the treatment prognosis is poor.
- Conditions
- Ischemia, Cerebrovascular Ischemia, Cognitive Impairment
- Trial name
- NCT05845983
- Testing
- Lactobacillus acidophilus, Maltodextrin
- Volunteers
- 236 people
- Sponsor
- Huaqiu Zhang
Stroke, Lacunar, Stroke, Acute Ischemic
Isosorbide Mononitrate and Butylphthalide to Reduce the Risk of Disability in Patients With Acute Lacunar Stroke (IMPACT)
The goal of this multicenter, double-blind, 2×2 factorial randomized controlled trial is to evaluate the efficacy and safety of isosorbide mononitrate, butylphthalide, and their combination in reducing disability in patients with…
- Conditions
- Stroke, Lacunar, Stroke, Acute Ischemic, Cerebral Small Vessel Diseases
- Trial name
- NCT07252544
- Testing
- Isosorbide Mononitrate, Butylphthalide
- Volunteers
- 3,156 people
- Sponsor
- Beijing Tiantan Hospital
Acute Ischemic Stroke
CompARing Between CO2 Phenylephrine and Phenylephrine Only Treatment in Patients With proGrEssing Cerebral infarctioN
Progressing stroke is associated poor functional outcome and neurological deficit. Currently, no treatment for progressing stroke is recommended on the guideline. Carbogen is a mixture of 5% CO2 with 95% O2.
- Trial name
- NCT06770426
- Testing
- carbogen with or without phenyleprhine, phenylephrine
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Stroke, Ischemic Stroke
Gravity Stroke System for Recanalization of Large Vessel Occlusion Strokes
Supernova and Neutron are endovascular mechanical revascularization devices indicated to restore blood flow by removing thrombus from a large intracranial vessel in patients experiencing an acute ischemic stroke within 24 hours…
- Conditions
- Stroke, Ischemic Stroke, Cerebrovascular Disorders, Brain Diseases
- Trial name
- GRASSROOT Reg (NCT07335185)
- Testing
- Supernova revascularization device
- Volunteers
- 3,000 people
- Sponsor
- Gravity Medical Technology, INC
Subarachnoid Aneurysm Hemorrhage, Cerebral Vasospasm After Subarachnoid Hemorrhage
Delayed Cerebral Infarction Beyond Endoluminal Spasmolysis and Induced Hypertension
An observational study of patients with emerging or established severe cerebral vasospasm after subarachnoid haemorrhage, employing multimodal neuromonitoring.
- Trial name
- Decibel (NCT07305922)
- Testing
- Induced hypertension with norepinephrine, Endoluminal Spasmolysis
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Region Stockholm
Cerebral Small Vessel Diseases, Cadasil
Taiwan Associated Genetic and Nongenetic Small Vessel Disease
The TAG-SVD enrolled patients with clinical and neuroimaging features of cerebral small vessel disease (CSVD). All enrolled patients will receive next-generation sequence (NGS) with probes designed to target five candidate CSVD…
- Conditions
- Cerebral Small Vessel Diseases, Cadasil, HTRA1-Related Autosomal Dominant Cerebral Angiopathy, COL4A1-Related Brain Small Vessel Disease With Haemorrhage
- Trial name
- TAG-SVD (NCT05473637)
- Testing
- MRI
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke
Association of Osmotic Drugs With Clinical Outcomes in Acute Large Hemispheric Infarction
Stroke remains the second leading cause of death worldwide, with 2%-8% of these being large hemispheric infarction (LHI) with an occupying effect and the worst prognosis.
- Trial name
- NCT05914272
- Testing
- Osmotic drugs
- Where
- 19 sites in China
- Volunteers
- 2,592 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Cerebral Infarction, Thrombolysis
Early Low-dose ASpirin Use After Intravenous Thrombolysis for Acute Ischemic Cerebral Infarction（ELASTIC）
This study evaluates whether early administration of low-dose aspirin (100mg) at 2 hours post-intravenous thrombolysis, compared to the standard timing of 24 hours, improves functional outcomes in patients with acute ischemic…
- Trial name
- ELASTIC (NCT07563673)
- Testing
- Aspirin (Early, 2h), Aspirin (Standard, 24h)
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Beijing Chao Yang Hospital