Clinical trials: Brain Injuries
Cerebral Palsy
Investigating the Effect of Stochastic Resonance Vibration on Gait and Balance and Upper Extremity Function in Children With Cerebral Palsy
The purpose of this research study is to determine the effects of wearable vibration devices for children with cerebral palsy and impaired arm function.
- Trial name
- NCT04388787
- Testing
- Stochastic resonance (SR) wraps
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Virginia Commonwealth University
Cerebral Palsy
Effectiveness of a Treatment With the Robot - Assisted Gait Training System Walkbot in Patients With Cerebral Palsy
The improvement of walking capacity is a key objective of the rehabilitation of children with PC. There are different approaches from physiotherapy to address this need, including walking on the ground and on treadmill with…
- Trial name
- NCT04329793
- Testing
- Assisted gait training with Walkbot System, Physical Therapy
- Where
- Spain
- Volunteers
- 23 people
- Sponsor
- Universidad de Murcia
TBI
Evaluation of Spot Light: A Concussion Injury Management App for Youth Sports
Sports-related traumatic brain injuries (TBIs), including mTBIs-commonly referred to as concussions-are a serious public health concern.
- Trial name
- SpotLight (NCT02249533)
- Testing
- Spot Light Concussion App
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Lara McKenzie
Hydrocephalus in Children, Epilepsy
Myelin Imaging Changes In Patients With Neurosurgical Diseases
Investigate myelin alterations in patients with neurosurgical diseases
- Conditions
- Hydrocephalus in Children, Epilepsy, Craniosynostoses, Traumatic Brain Injury
- Trial name
- McDESPOT (NCT03698838)
- Testing
- McDESPOT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Memorial Healthcare System
Brain Injuries, Disorder of Consciousness
Verticalization Robotic Exoskeleton DoC
Mobilization, specifically verticalization, has been shown to play a role in enhancing consciousness. Vestibular stimulation has the potential to influence the neural substrate of consciousness, but this modality has not been…
- Trial name
- NCT04833543
- Testing
- Robotic Mobility Device (REX), Tilt Table
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Memorial Hermann Health System
Cerebral Palsy Infantile, Neuromuscular Diseases in Children
Virtual Reality Impact on Powered Mobility: a Feasibility Study
This study explores the potential of Virtual Reality (VR) technology to enhance powered wheelchair (PW) training for children diagnosed with Cerebral Palsy (CP) and neuromuscular diseases (NMDs).
- Trial name
- VR-PMP (NCT06586125)
- Testing
- Powered Mobility Training
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Azienda Usl di Bologna
Cerebral Palsy
The Effect of Exercise Training on Musculoskeletal Health in Individuals With Cerebral Palsy
Cerebral palsy (CP) is a neurodevelopmental disorder and is the most common childhood disability. CP is characterized by abnormal development, impaired motor function, and muscular and skeletal abnormalities.
- Trial name
- NCT05070117
- Testing
- Exercise training
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- San Jose State University
Stroke, Ischemic, Stroke Hemorrhagic
Exploring Accessible Beauty for Individuals With Upper Extremity Deficits
The purpose of this study is to investigate the accessibility of beauty products for individuals with upper extremity disabilities.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke (CVA) or TIA, Stroke, Acute
- Trial name
- NCT05945784
- Testing
- Use of Rare Beauty makeup products
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Brain Damage
Transcranial Doppler and Quantitative Pupillometry as Neurological Prognostic Factors in Brain Damaged Patients Admitted to Intensive Care Unit
Transcranial Doppler is performed daily in Intensive Care Unit in brain damaged patients. For a few years now, the measurement of the photomotor reflex by quantitative Pupillometry has been routinely performed in Intensive Care…
- Trial name
- NCT04846738
- Testing
- Transcranial Doppler, Pupillometry.
- Where
- France
- Volunteers
- 73 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Neurologic Diseases, Hemiparesis
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one…
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies
- Trial name
- NCT04798378
- Testing
- Neurosleeve
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Post Traumatic Stress Disorder, Traumatic Brain Injury
Rapid Treatment of PTSD With Accelerated Non-Invasive Brain Stimulation
This study will test the clinical efficacy of an accelerated TMS (accel-TMS) protocol that rapidly addresses PTSD symptoms with 1 week (25 sessions over 5 days) of condensed treatment.
- Trial name
- NCT06544408
- Testing
- Cool B70 AP Coil - Active (dl-PFC), Cool D-B80 AP Coil - Active (dm-PFC), Cool B70 Treatment Coil - Active Only
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Florida State University
Mild Traumatic Brain Injury
Regulation of Emotion, Sleep Extension, and mTBI
Concussions are incredibly common, and often result in severe and long lasting symptoms, including, but not limited to, sleep deprivation and emotion dysregulation.
- Trial name
- RESET (NCT06883006)
- Testing
- Sleep Extension
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Merrimack College
Disorders of Consciousness, Vegetative State
AI-Assisted Precision Hyperbaric Oxygen Therapy Based on Dynamic BIS-EEG Feedback for Patients With Disorders of Consciousness
Disorders of consciousness (DoC) are severe neurological conditions characterized by impaired awareness and reduced interaction with the environment.
- Conditions
- Disorders of Consciousness, Vegetative State, Minimally Conscious State
- Trial name
- AI-HBOT-DoC (NCT07855848)
- Testing
- AI-Assisted Personalized Hyperbaric Oxygen Therapy, Conventional Hyperbaric Oxygen Therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Cerebral Palsy
The Caregiver's Burden in Cerebral Palsy
Cerebral palsy (CP) results from damage to the developing brain of the fetus or infant. These non-progressive lesions cause a set of permanent movement and posture disorders, responsible for activity limitations.
- Trial name
- NCT04521855
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Tatiana Besse-Hammer
Hemispatial Neglect, Hemiplegia
The Effects of Offline Anosognosia For Spatial Neglect on Neglect Rehabilitation
Anosognosia for hemispatial neglect is an intriguing phenomenon characterized by decreased awareness of spatial deficits, common in patients with right hemisphere stroke.
- Conditions
- Hemispatial Neglect, Hemiplegia, Right Hemispheric Stroke, Anosognosia
- Trial name
- NCT05145855
- Testing
- Patient-tailored multimodal neglect rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Gazi University
Brain Concussion, Mild Traumatic Brain Injury
Rehabilitation, Education, and SElf-management for Adolescents After Mild Traumatic Brain Injury
Concussion or mild traumatic brain injury (mTBI) is a major public health concern. Most adolescents will recover from mTBI without complication; however, a sizeable minority experience symptoms that last more than one most…
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Concussion
- Trial name
- RESET (NCT07698015)
- Testing
- Mindfulness-based intervention, Health Education
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Molly Cairncross
Cerebral Palsy
How Much Virtual Reality Intervention Improve the Balance of Patients With Cerebral Palsy
The purpose of this clinical study is to investigate how effective virtual reality applications are in adult cerebral palsy rehabilitation.
- Trial name
- NCT06769178
- Testing
- Virtual Reality based
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Yeditepe University
Cerebral Palsy
Innovative Robotic Gait Trainer Use to Enable Walking in Children With Cerebral Palsy GMFCS III and IV
Exploration to optimize mixed quantitative and qualitative methodology using multiple outcome measures in a randomized, cross-over trial structure comparing the effect of robotic gait training (RGT) group, and functional clinical…
- Trial name
- NCT05378243
- Testing
- Robotic Gait Training, Functional Clinical Therapy
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Eastern Ontario
Traumatic Brain Injury
Doxycycline in Acute Traumatic Brain Injury
evaluate the impact of Doxycycline on both clinical outcome and blood levels of NSE in patients with TBI.
- Trial name
- NCT04239755
- Testing
- Doxycycline 100 MG Oral Tablet
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Damanhour University
Apoplexy, Femoral Neck Fracture
Epidemiology of Aeromedical Evacuation
Increasing air travel has resulted in a significant increase in aeromedical evacuation over the past decade. However there is only a small amount of epidemiological data available on the diagnosis, costs and transport…
- Conditions
- Apoplexy, Femoral Neck Fracture, Myocardial Infarction, Subarachnoid Hemorrhage
- Trial name
- NCT01071382
- Volunteers
- 504 people
- Sponsor
- Ruhr University of Bochum