Clinical trials: Brain Mapping, open to volunteers
Glioma, Brain Tumor Adult
Movie-Watching Functional MRI for Mapping Brain Function in Neurosurgical Patients
This research will compare a new type of functional MRI (fMRI) called naturalistic viewing (also called movie watching) to standard clinical fMRI techniques.
- Trial name
- NCT07650994
- Testing
- Functional magnetic resonance imaging (fMRI), Neuropsychological Assessments
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Brigham and Women's Hospital
Brain Mapping, Healthy Volunteer
Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle
Background: Magnetic resonance imaging (MRI) is a widely used scanning technique to obtain images of the human body and evaluate activity in the brain.
- Trial name
- NCT01266577
- Testing
- NSR MAGNETOM 7T, 1Tx x 32Rx Head Coil
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Inflammation, Stress
Mapping the Effect of (neuro)inflammation on Stress Sensitivity in the Brain of Healthy Men
The goal of this interventional study is to determine the effects of inflammation on stress responses in the brain of healthy men.
- Conditions
- Inflammation, Stress, Healthy Volunteer
- Trial name
- INFLAMES (NCT06620679)
- Testing
- Lipopolysaccharide (LPS)
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Neurodegeneration With Brain Iron Accumulation (NBIA), Iron Metabolism Disorders
Brain Iron in Beta-Propeller Protein Associated Neurodegeneration (BPAN)
This study aims to quantify intracerebral iron load in patients with Beta-Propeller Protein-Associated Neurodegeneration (BPAN) using Quantitative Susceptibility Mapping (QSM) technique.
- Conditions
- Neurodegeneration With Brain Iron Accumulation (NBIA), Iron Metabolism Disorders, Brain Disease
- Trial name
- QUBIPAN (NCT07868120)
- Testing
- Standardized brain MRI including specific sequences usable for Quantitative Susceptibility Mapping (QSM)
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Bordeaux
Cerebral Autoregulation Mapping
Non-Invasive Mapping of Cerebral Autoregulation Using Near Infrared Spectroscopy
The investigators propose to employ advanced multi-channel near non-invasive near infrared spectroscopy (NIRS) system married with entirely non-invasive continuous arterial blood pressure (niABP) monitor to create a new wearable…
- Trial name
- NCT05433129
- Testing
- Transient hyperemic response, Orthostatic challenge, Vascular chemo-reactivity
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Multiple Sclerosis, Secondary Progressive, Multiple Sclerosis
Cladribine vs Placebo for Non-active Progressive Multiple Sclerosis (CLASP-MS).
The purpose of the study is to evaluate the efficacy and safety of subcutaneously administered cladribine versus placebo to stop inflammation and treat disease progression of non-active secondary progressive multiple sclerosis.
- Trial name
- CLASP-MS (NCT05961644)
- Testing
- Cladribine Subcutaneous Injection, 0.9% Chloride Injection Sodium
- Where
- Poland
- Volunteers
- 188 people
- Sponsor
- Institute of Psychiatry and Neurology, Warsaw