Clinical trials: Brain Stroke
Ischemic Stroke
Mayo Acute Stroke Trial for Enhancing Recovery
This study involves treating patients that have suffered an acute ischemic stroke with the medication donepezil (Aricept ®). The hypothesis is that taking donepezil (FDA-approved for the treatment of Alzheimer's Disease) for the…
- Trial name
- MASTER (NCT00805792)
- Testing
- Donepezil
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Mayo Clinic
Aphasia, Acquired
Word Retrieval in the Wild in People With Post-Stroke Aphasia
People with post-stroke aphasia (PWA) suffer from anomia, a condition where they know what they want to say but cannot retrieve the words.
- Trial name
- NCT05338216
- Testing
- Traditional EMA, Micro-Interaction EMA
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Northeastern University
Stroke, Acute
Rate of Atrial Fibrillation Through 12 Months in Patients With Recent Ischemic Stroke of Presumed Known Origin
The purpose of the Stroke AF study is to compare the incidence of atrial fibrillation (AF) through 12 months between continuous cardiac rhythm monitoring with the Reveal LINQ™ Insertable Cardiac Monitor (ICM) (continuous…
- Trial name
- NCT02700945
- Testing
- Reveal LINQ™ Insertable Cardiac Monitor
- Where
- 35 sites in United States
- Volunteers
- 496 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Stroke
Neurofeedback for Stroke Rehabilitation
Real-time neurofeedback aims to alter brain activation patterns through online feedback of ongoing brain activity using magnetic resonance imagining (MRI).
- Trial name
- NCT03775915
- Testing
- Neurofeedback
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University of Oxford
Stroke
Robotic Therapy and Transcranial Direct Current Stimulation in Patients With Stroke
Stroke is the second cause of death worldwide and represented the first cause of death in Brazil between 2006 and 2010. Most patients survive, and there is a need to develop cost-effective rehabilitation strategies to decrease…
- Trial name
- ROTS (NCT02416791)
- Testing
- Robotic Therapy, Active tDCS, Physical Therapy
- Where
- Brazil
- Volunteers
- 9 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke
rTMS Combined With BWSTT in Stroke With Body Weight Supported Treadmill Training (BWSTT) After Stroke
The study will enroll 5 individuals post-stroke to examine the feasibility and efficacy of a high frequency repetitive transcranial magnetic stimulation (rTMS) combined with body weight supported treadmill training.
- Trial name
- NCT03441334
- Testing
- High Frequency rTMS
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Texas Woman's University
Ischemic Stroke, Acute, Brain Diseases
Safety and Efficacy of SINOMED SR for Endovascular Treatment of Acute Ischemic Stroke
A prospective, multicenter, randomized controlled, non-inferiority study to investigate the effectiveness and safety of SINOMED SR for endovascular treatment of acute ischemic stroke
- Conditions
- Ischemic Stroke, Acute, Brain Diseases, Cerebrovascular Disorders
- Trial name
- NCT04973332
- Testing
- Intracranial thrombectomy stent
- Where
- 14 sites in China
- Volunteers
- 218 people
- Sponsor
- Sinomed Neurovita Technology Inc.
Rehabilitation, Recovery of Function
Functional Viability Duck Duck Punch
This study has 2 parts: In one part of this study, people with stroke will either play a custom designed computer game for stroke rehabilitation called Duck Duck Punch or an off the shelf computer game with their weaker arm 3…
- Conditions
- Rehabilitation, Recovery of Function, Stroke
- Trial name
- DDPSBIR (NCT03053492)
- Testing
- Duck Duck Punch Play, Commercially Available Game Play
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Medical University of South Carolina
Stroke
Evaluation of a CarePartner-Integrated Telehealth Rehabilitation Program for Persons With Stroke
The objective of this study is to identify the potential benefits of a home-based, intervention designed to facilitate carepartners' roles in stroke survivor rehabilitation.
- Trial name
- CARE-CITE (NCT02703532)
- Testing
- CARE-CITE Education Program, Traditional Education, Constraint-Induced Movement Therapy (CIMT)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Emory University
Stroke
PROPEL Randomized Trial
It is important for people with stroke to exercise in order to improve their overall recovery and general health. However, these individuals are less physically active than people without stroke, and they often do not achieve the…
- Trial name
- NCT02951338
- Testing
- PROPEL program, Group aerobic exercise
- Where
- 5 sites in Canada
- Volunteers
- 57 people
- Sponsor
- Toronto Rehabilitation Institute
Post Stroke Epilepsy
Anti-epileptogenic Effects of Eslicarbazepine Acetate
This study aims to assess if eslicarbazepine acetate (ESL) treatment (started within 96 hours after stroke occurrence and continued for 30 days) changes the incidence of unprovoked seizures (USs) within the first 6 months after…
- Trial name
- NCT06597084
- Testing
- ESL 800 mg
- Where
- 22 sites in Austria, France and 7 more
- Volunteers
- 129 people
- Sponsor
- Bial - Portela C S.A.
Ischemic Stroke
Safety of Intravenous Thrombolysis for Wake-up Stroke
The purpose is to demonstrate the safety of intravenous tissue plasminogen activator (IV t-PA) in ischemic stroke patients who present to the emergency department (ED) after awakening with the symptoms of suspected ischemic…
- Trial name
- Wake-Up Stroke (NCT01183533)
- Testing
- Alteplase (iv t-PA)
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke
Targeted High-definition Transcranial Direct Current Stimulation (HD-tDCS) for Reducing Post-stroke Movement Impairments
Stroke is the leading cause of serious, long-term disability. The emergence of abnormal muscle synergies following a stroke presents a major limitation to the recovery of independent function.
- Trial name
- NCT05174949
- Testing
- Transcranial direct current stimulation (high-definition)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Oklahoma
Subarachnoid Hemorrhage, Subdural Hematoma
Efficacy of Bromocriptine For Fever Reduction in Acute Neurologic Injury
The purpose of this study is to evaluate the antipyretic effect of bromocriptine in critically-ill patients with acute neurologic injury and fever from infectious and non-infectious etiologies.
- Conditions
- Subarachnoid Hemorrhage, Subdural Hematoma, Traumatic Brain Injury, Ischemic Stroke
- Trial name
- BFF (NCT03496545)
- Testing
- Bromocriptine 5 MG, Acetaminophen 650 MG
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- University of California, San Francisco
Atrial Fibrillation, Stroke
Patient Convenience Study (RE-SONANCE)
The aim of this non-interventional study is to describe patient's perception of anticoagulant treatment when using Pradaxa to prevent stroke and systemic embolism while suffering from atrial fibrillation (according to its…
- Trial name
- NCT02684981
- Where
- 12 sites in Austria, Bulgaria and 10 more
- Volunteers
- 9,472 people
- Sponsor
- Boehringer Ingelheim
Atrial Fibrillation, Stroke
Philips Intracardiac Echocardiography (ICE) Clinical Registry
The purpose of this observational registry is to report real-world safety and performance of VeriSight for ultrasound guided ICE imaging in percutaneous cardiac intervention procedures when used in standard clinical practice.
- Conditions
- Atrial Fibrillation, Stroke, Valve Disease, Heart, Atrial Septal Defect
- Trial name
- NCT04950192
- Testing
- ICE Image guidance
- Where
- 5 sites in United States
- Volunteers
- 155 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Atrial Fibrillation
mHealth Screening to Prevent Strokes
The purpose of this study is to investigate whether it is possible to identify a high-risk cohort suitable for screening for asymptomatic atrial fibrillation using claims data, and then engage those individuals in a mobile health…
- Trial name
- mSToPS (NCT02506244)
- Testing
- iRhythm ZIO XT Patch, Wristband by Amiigo
- Where
- United States
- Volunteers
- 6,135 people
- Sponsor
- Scripps Translational Science Institute
Acute Ischemic Stroke
Caffeinol Hypothermia Protocol
Caffeinol is a combination of caffeine and alcohol. The amount given is about the same as 1-2 glasses of wine and 3-4 cups of coffee. The patient receives a one time dose given over two hour while being cooled to 34.5 C.
- Trial name
- NCT00299416
- Testing
- Caffeinol, hypothermia
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke
A Pilot Study of Robot-assisted Therapy for Post-stroke Forearm and Wrist Rehabilitation Training
A pilot study to assess the effectiveness of CR2-Haptic and determine the feasibility of including robotic therapy into the daily rehabilitation program.
- Trial name
- NCT02274675
- Testing
- Robot-assisted therapy for wrist and forearm, Standard rehabilitation therapy
- Where
- Malaysia
- Volunteers
- 7 people
- Sponsor
- Universiti Teknologi Malaysia
Stroke
Post-marketing Clinical Study of Alteplase for Acute Ischemic Stroke （Japan Alteplase Clinical Trial Ⅱ：J-ACT Ⅱ）
The purpose of this study is to confirm the efficacy and safety of intravenously administered alteplase in patients with acute ischemic stroke based on the rate of recanalization assessed by magnetic resonance angiography (MRA)…
- Trial name
- NCT00412867
- Testing
- Alteplase
- Where
- Japan
- Volunteers
- 58 people
- Sponsor
- Tanabe Pharma Corporation