Clinical trials: Brain Stroke
Stroke
Guideline - Based Nursing Plan for Dysphagia After Stroke
Research purposes:1, investigate the nursing management is the head nurse for swallowing disorder after stroke care management status; Compared with the existing research, the difference between guidelines and evidence-based…
- Trial name
- NCT04956471
- Testing
- interview
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking University Third Hospital
Atrial Fibrillation, Deep Vein Thrombosis
Weekly Monitoring Strategy of Capillary INR Versus Monthly Monitoring Strategy of Venous INR in Elderly Patients in a Nursing Home.
This primary care study aims to compare the "time in therapeutic range" (TTR) of two strategies for monitoring the international normalized ratio (INR) over 6 months in nursing homes.
- Conditions
- Atrial Fibrillation, Deep Vein Thrombosis, Stroke
- Trial name
- INR-CAP (NCT05561244)
- Testing
- Weekly monitoring using the capillary International Normalised Ratio strategy
- Where
- 33 sites in France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
PFO, PFO - Patent Foramen Ovale
Early Feasibility Study (EFS) Evaluating Percutaneous Repair of the Atrial Septum With a Novel PFO Occluder: The PROTEA-PFO Study
The goal of this clinical trial is to test a new heart device called P3 Occluder System in patients who have a small opening between the upper chambers of the heart (called a Patent Foramen Ovale or PFO) and have experienced a…
- Conditions
- PFO, PFO - Patent Foramen Ovale, Cryptogenic Stroke, Patent Foramen Ovale
- Trial name
- PROTEA-PFO (NCT07172464)
- Testing
- Recross P3 Occluder (P3O) System
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Recross Cardio, Inc.
Acute Ischemic Stroke
rhTNK-tPA for Acute Ischemic Stroke Under Simplified Imaging in the Extended Time Window
The PEARL-SIMPLIFIED trial is a multicenter, prospective, randomized controlled, open-label, blinded-endpoint study. It aims to evaluate the efficacy and safety of intravenous tenecteplase (TNK) in patients with acute ischemic…
- Trial name
- SIMPLIFIED (NCT07606807)
- Testing
- Tenecteplase (rhTNK-tPA) (0.25 mg/kg, to maximum of 25mg), Standard medical treatment
- Where
- China
- Volunteers
- 750 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Right Hemispheric Stroke, Left Hemispheric Stroke
Neural and Cognitive Correlates of Pragmatic Abilities
Pragmatics of language refers to the set of abilities that allow one to use and interpret language according to context and, in general, to communicate effectively.
- Conditions
- Right Hemispheric Stroke, Left Hemispheric Stroke, Traumatic Brain Injury, Right Hemispheric Brain Tumor
- Trial name
- APACS_Neuro (NCT06297044)
- Testing
- Neuropsychological assessment
- Where
- Italy
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Family Caregivers of Stroke Survivors, Stroke
Telephone Assessment and Skill-Building Kit (TASK): A New Program for Family Caregivers of Stroke Survivors
The purpose of this study is to test a new educational program for families taking care of persons who have had a stroke. Caregivers are asked what they think of the TASK program and how to make it better.
- Trial name
- NCT00264745
- Testing
- TASK intervention, Attention Control
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cerebrovascular Accident
Norwegian Constraint-Induced (CI) Therapy Multisite Trial
The purpose of this study is to determine whether modified CI therapy treatment is suitable and effective in the early rehabilitation after stroke, and to compare early CI intervention with a later CI intervention group.
- Trial name
- NORCIMT (NCT00906477)
- Testing
- Modified CI therapy
- Where
- 5 sites in Norway
- Volunteers
- 47 people
- Sponsor
- University Hospital of North Norway
Stroke
NeuroReAlign Therapy for Cognitive Rehabilitation in Patients with Stroke
The goal of this randomized controlled trial is to investigate the effects of NeuroReAlign Therapy on cognition in stroke survivors in the chronic stage (>6 months).
- Trial name
- NCT06849128
- Testing
- NeuroReAlign Therapy, Conventional cognitive training
- Volunteers
- 30 people
- Sponsor
- Middle East University
Ischemic Stroke
Improve Acute Reperfusion Treatment Quality for Stroke in China, IMPROVE: Stroke Care in China
In order to bridge the great gaps, Chinese Stroke Association (CSA) and American Heart Association (AHA) sought to develop, conduct, and assess a multifaceted quality improvement intervention to increase the adherent rate of IV…
- Trial name
- NCT03578107
- Testing
- improvement of quality of stroke care
- Where
- China
- Volunteers
- 15,895 people
- Sponsor
- Beijing Tiantan Hospital
Frontotemporal Dementia, Right Sided Cerebral Hemisphere Cerebrovascular Accident
Efficacy of Web-Based Social-Cognitive Interventions in Right Hemisphere Stroke and Frontotemporal Dementia
This study is being done to test the feasibility and effectiveness of web-based social-cognitive training exercises in treating social-emotional deficits in patients with stroke or frontotemporal dementia (FTD).
- Trial name
- NCT02506036
- Testing
- Brain HQ
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Johns Hopkins University
Stroke, Electroencephalography
Effect of Dual-task Training on the Number of EEG Band in Stroke Patients
Stroke is a prevalent global health concern, causing widespread disability as it disrupts blood supply to the brain, leading to functional impairments.
- Trial name
- NCT06286436
- Testing
- Dual-task training
- Where
- Iran
- Volunteers
- 5 people
- Sponsor
- Universidad de Zaragoza
Acute Ischemic Stroke
Clopidogrel Plus Aspirin in Acute Ischemic Stroke Following Thrombectomy and/or Intravenous Thrombolysis (CoPrime)
Stroke is a common cause of disability. The most common type of stroke, an ischemic stroke, is caused by a blood vessel in the brain getting blocked by a clot.
- Trial name
- CoPrime (NCT06638151)
- Testing
- aspirin + clopidogrel, Aspirin
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of Alberta
Ischemic Stroke
Correlation Between Brain Structure and Activity and Spontaneous Recovery of Motor Function Following Brain Ischemic Stroke
The investigator aims to find a correlation between brain structure and activity and spontaneous recovery of motor function following brain ischemic stroke by Analysis of MRI scans.
- Trial name
- NCT05889429
- Testing
- MRI scans, clinical assessments
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Technion, Israel Institute of Technology
Acute Stroke
Tirofiban for the Prevention of Neurological Deterioration in Acute Ischemic Stroke
Currently, dual antiplatelet therapy with aspirin and clopidogrel (with loading doses) is widely used for patients with acute ischemic stroke.
- Trial name
- TREND (NCT04491695)
- Testing
- Tirofiban Hydrochloride, Oral antiplatelet
- Where
- 19 sites in China
- Volunteers
- 420 people
- Sponsor
- Capital Medical University
Atrial Fibrillation, Stroke
Transesophageal Echocardiography to Identify pAtients With Low Risk of Stroke in Atrial Fibrillation - TIARA Pilot Study
In this multi centre pilot study we will perform TEE in patients with AF who are eligible for VKA treatment. TTE will be used as pre-screening: if TTE shows left atrial abnormalities or aortic plaque, patients will be excluded…
- Trial name
- TIARA (NCT00224757)
- Testing
- Transoesophageal echocardiography
- Where
- 10 sites in Netherlands
- Volunteers
- 227 people
- Sponsor
- The Interuniversity Cardiology Institute of the Netherlands
Alzheimer Disease, Parkinson Disease
Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies
The role of disorders of socio-emotional processes in cerebral diseases such as Alzheimer's disease, frontal temporal dementia, Parkinson's disease, Huntington's disease, traumatic brain injury, stroke, focal lesions, has been…
- Conditions
- Alzheimer Disease, Parkinson Disease, Frontal Dementia, Huntington Disease
- Trial name
- GREFEXII (NCT03052712)
- Testing
- social cognition
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Acute Stroke
A Study to Evaluate the Effects of the Neuroflo Device in People Who Have Had a Stroke
Patients with acute ischemic stroke and persistent arterial occlusion following failed mechanical revascularization, who can undergo NeuroFlo treatment within 18 hours of last time symptom free, will be eligible for enrollment to…
- Trial name
- PAO (NCT00653536)
- Testing
- NeuroFlo
- Where
- United States
- Sponsor
- University of California, Los Angeles
Stroke, Patent Foramen Ovale
AMPLATZER PFO Occluder Post Approval Study
The purpose of this single arm, multi-center study is to confirm the safety and effectiveness of the AMPLATZER™ PFO Occluder in the post Approval Setting.
- Trial name
- PFO PAS (NCT03309332)
- Testing
- AMPLATZER™ PFO Occluder
- Where
- 88 sites in United States, Canada and 5 more
- Volunteers
- 1,214 people
- Sponsor
- Abbott Medical Devices
Ischemic Stroke
Study to Examine the Effects of MultiStem in Ischemic Stroke
A study to examine the safety and potential effectiveness of the adult stem cell investigational product, MultiStem, in adults who have suffered an ischemic stroke.
- Trial name
- NCT01436487
- Testing
- MultiStem
- Where
- 32 sites in United States, United Kingdom
- Volunteers
- 134 people
- Sponsor
- Healios K.K.
Stroke, Acute, Hemorrhage
Feasibility of Improving Cerebral Autoregulation in Acute Intracerebral Haemorrhage
In the UK, 23,000 (15%) of the 150,000 people who suffer a stroke each year have bleeding in the brain, also referred to as acute intracerebral haemorrhage (ICH).
- Conditions
- Stroke, Acute, Hemorrhage, Cerebral Brain Hemorrhage, Blood Pressure
- Trial name
- BREATHE-ICH (NCT03324321)
- Testing
- Hypocapnia via Hyperventilation Protocol
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Leicester
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