Clinical trials: Brain Stroke
Stroke
Clinical Applicability of Robot-assisted Gait Training System in Acute Stroke Patients
Investigation of the clinical feasibility and efficacy of a newly developed robot-assisted gait training system for acute stroke survivors.
- Trial name
- NCT02755415
- Testing
- HIWIN Robotic Gait Training System, Static Standing Table
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Stroke (CVA) or TIA, Headache, Migraine
Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache
Post stroke headache occurs in approximately 10-23% of all stroke patients. Its onset is shortly after experiencing a stroke, or stroke like event, and persists for at least three months.
- Conditions
- Stroke (CVA) or TIA, Headache, Migraine, Botulinum Toxins, Type A, Cerebral Venous Sinus Thrombosis
- Trial name
- NCT04580238
- Testing
- Botox 200 UNT Injection, Non Botox based Standard of Care Treatments for Headache/Migraine
- Where
- Canada
- Sponsor
- University of Alberta
Stroke, Aphasia
Effects of Transcranial Direct Current Stimulation (tDCS) on Brain Organization and Naming in Aphasic Patients.
High-Definition Transcranial Direct Current Stimulation (HD-tDCS) allows to induce, in a non-invasive way, a transient inhibitory or excitatory neuromodulation of a given cerebral region and to obtain a very focused cortical…
- Trial name
- NCT05570578
- Testing
- HD-tDCS
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- Adrian Guggisberg
Hemorrhage, Pneumonia
Oral Hygiene and Prophylactic Antibiotics to Prevent Intracerebral Hemorrhage Associated Pneumonia
Project Name: Randomized Controlled Clinical Study on oral hygiene and prophylactic antibiotics to prevent Intracerebral Hemorrhage associated pneumonia Research Objectives: To evaluate the effectiveness, safety and health…
- Trial name
- OCEAN (NCT07311343)
- Testing
- wether apply enhanced oral care combined with prophylactic antibiotics
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Ischemic, Hemianopia, Homonymous
Statistical Learning as a Novel Intervention for Cortical Blindness
This project aims to develop a novel visual training paradigm for use in visually-intact participants and those sufferings from stroke-induced visual impairments.
- Conditions
- Stroke, Ischemic, Hemianopia, Homonymous, Hemianopsia, Occipital Lobe Infarct
- Trial name
- NCT06578117
- Testing
- Vision Training and Learning Task
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Central Apnoeas, Stroke Patients
Pathophysiology of Central Apnoeas in Stroke Patients
40% of patients with Sleep Disorder Breathing (SDB) appearing during the acute phase of stroke show a respiratory pattern characterized by central apnoeas and/or periodic breathing.
- Trial name
- NCT01723189
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MPons
Stroke
Evaluation of Sensorimotor Ankle Impairments in Chronic Stroke
The purpose of this study is to capture sensorimotor ankle function in a chronic stroke population through validation of novel, experimental metrics and their comparison with established, clinical measures of function.
- Trial name
- NCT06410989
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Rehabilitation, Stroke
Short-Term Effects of Whole-Body Vibration on Upper Extremity Function in Subjects With Poststroke Hemiplegia
To investigate the effect of whole body vibration on upper limb motor function in hemiplegic patients with subacute stroke
- Conditions
- Rehabilitation, Stroke, Hemiplegia, Physical Therapy Modalities
- Trial name
- NCT03963258
- Testing
- whole-body vibration training, conventional upper limb training
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Stroke
Post-stroke Nurse-led Rehabilitation to Improve Functional Activity and Community Participation in Bangladesh
Stroke causes various levels of disability which decreases physical function for a prolonged period. The purpose of this study is to evaluate the effectiveness of a nurse-led rehabilitation program including a multidisciplinary…
- Trial name
- NCT07384650
- Testing
- in daily routine practice
- Where
- Bangladesh
- Volunteers
- 166 people
- Sponsor
- Hiroshima University
Stroke
Continuous Video- EEG Monitoring in the Acute Phase in Patients With a Cerebrovascular Attack- Randomisation of a Subpopulation Regarding Treatment Strategy
Stroke is a major cause of epilepsy. The pathophysiological mechanisms of poststroke epilepsy are not known. Subclinical epileptiform discharges could contribute to the neuronal damage and influence functional outcome.
- Trial name
- Video-EEG (NCT01862952)
- Testing
- starting of anti-epileptic drug treatment
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Cognitive Decline, Stroke
Identification of Epigenetic Risk Factors for Ischemic Complication During the TAVR Procedure in the Elderly
Over the past ten years, the number of endovascular procedures has increased by 5% per year in Europe with the development of interventional cardiology, such as percutaneous coronary angioplasty, aortic valve replacements (TAVR)…
- Trial name
- METHYSTROKE (NCT02972008)
- Where
- France
- Volunteers
- 542 people
- Sponsor
- University Hospital, Lille
Ischemic Stroke
A Phase 2b Study of Dalfampridine 10mg Extended Release Tablet in Subjects With Chronic Deficits After Ischemic Stroke
This is a multi-center, safety and tolerability study in subjects with chronic stable sensorimotor deficits after ischemic stroke. It has been designed as a double-blind, placebo-controlled, 2-period crossover study.
- Trial name
- NCT01605825
- Where
- 20 sites in United States
- Volunteers
- 83 people
- Sponsor
- Acorda Therapeutics
Stroke
Cognitive Impact of Pomegranate Polyphenols Following Ischemic Stroke
The purpose of this study is to determine whether pomegranate supplements improve cognitive functioning following stroke.
- Trial name
- NCT02442804
- Testing
- POMx
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Loma Linda University
Stroke, Control Condition
Vision and Proprioception Evaluation With Robotics After Stroke
Stroke is highly prevalent in Canada and can lead to profound upper limb impairments in motor and sensory function, as well and vision.
- Trial name
- VIPERS (NCT07254949)
- Where
- 2 sites in Canada
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Dr. Sean Dukelow
Chronic Stroke, Cognitive Impairment
pBFS-guided iTBS Over the Left DLPFC for Chronic PSCI
The study aims to investigate the efficacy and safety of intermittent theta burst stimulation (iTBS) guided by the personalized Brain Functional Sector (pBFS) technique in the treatment of patients with chronic post-stroke…
- Trial name
- NCT05953415
- Testing
- active iTBS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Changping Laboratory
Stroke
Non-Invasive Brain Signal Training to Induce Motor Control Recovery After Stroke
The purpose of this trial was to evaluate the benefits of combination motor learning training and brain computer interface training for restoring arm function in people with stroke.
- Trial name
- NCT00746525
- Testing
- Surface functional electrical stimulation (FES), Motor learning, Brain computer interface (BCI) training
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Louis Stokes VA Medical Center
Acquired Brain Injury (Including Stroke)
Testing a Group Memory Training Program for People With Brain Injuries
The purpose of this study is to assess the feasibility, acceptability, and effectiveness of a 6-week group-based memory training program for individuals experiencing memory problems after acquired brain injury (ABI).
- Trial name
- NCT06800040
- Testing
- Memory training
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- University Hospital of North Norway
Stroke, Ischemic Stroke
Intravenous Magnesium Sulphate in Acute Ischemic Stroke
Magnesium has a neuroprotective role so the investigators aim to evaluate the role of intravenous magnesium sulphate in improving the clinical outcomes as assessed by the NIH Stroke Scale (NIHSS) in patients with acute ischemic…
- Trial name
- NCT04412850
- Testing
- Magnesium Sulfate
- Volunteers
- 44 people
- Sponsor
- Dow University of Health Sciences
Aphasia, Acquired, Language Disorders
Enhancing Language Function in Aphasia
Aphasia is an acquired impairment of language, that commonly results from damage to language areas in the brain (typically the left side of the brain).
- Conditions
- Aphasia, Acquired, Language Disorders, Primary Progressive Aphasia, Stroke, Cerebrovascular
- Trial name
- NCT05443633
- Testing
- individualized speech-language training, standard language intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Stroke, Hemiplegia
Robot-Assisted Stroke Rehabilitation Based on Patient-Therapist Interactions
Our study goal is to assess natural patient-therapist interactions in order to map such human-human activities to robot-human interactions.
- Conditions
- Stroke, Hemiplegia, Healthy
- Trial name
- Baxter (NCT02806843)
- Testing
- Rehab InterCap system and 3D Kinect
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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