Clinical trials: Brain Stroke
Stroke, Cerebral Vascular Accident
Transcranial Direct Current Stimulation for Improving Gait Training in Stroke
The purpose of this study is to determine if transcranial direct current stimulation (tDCS)applied over the lower extremity motor cortex in conjunction with assisted gait training is effective for improving gait in patients with…
- Trial name
- NCT01807637
- Testing
- transcranial direct current stim (tDCS)
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Arkansas
Stroke, Ischemic
Differential Metabolic Signature of Stroke Patients Undergoing Thrombolysis
Currently, there is no reliable biomarker for stroke, meaning that treatment is often delayed and patients are often left with a disability.
- Trial name
- DETECT (NCT03443245)
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Gastrointestinal Microbiome
Cognition and Gut Microbiome Associated Study of Shanghai People With Acute Ischemic Stroke
The purpose of this study is to evaluate the effect of probiotics on the gut microbiome of ischemic stroke patients.
- Trial name
- NCT03812445
- Testing
- Probiotics
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai 10th People's Hospital
Stroke, Self Efficacy
Visual Arts-based Intervention for Community-dwelling Stroke Survivors
Stroke is the major cause of disability worldwide and leads to psychosocial issues for community-dwelling stroke survivors in their recovery journey.
- Conditions
- Stroke, Self Efficacy, Psychosocial Problem
- Trial name
- NCT06395857
- Testing
- Visual arts-based intervention
- Where
- Macau
- Volunteers
- 32 people
- Sponsor
- The Nethersole School of Nursing
Stroke
Breakfast Group Interventions in Stroke Rehabilitation
Current evidence shows that many people living with stroke experience major problems with eating and drinking. We know that this can lead to malnutrition, dehydration, reduced muscle strength and depression.
- Trial name
- BISTRo (NCT05102812)
- Testing
- Breakfast Group Intervention
- Where
- United Kingdom
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Ischemic Stroke
Intervention to Bridge the Evidence-based Gap in Stroke Care Quality
The purpose of this study is to evaluate whether a multifaceted quality improvement intervention can improve the adherent rate of individual and composite of evidence-based performance measures for patients with acute ischemic…
- Trial name
- GoldenBridge (NCT02212912)
- Testing
- improvement intervention, no intervention
- Where
- China
- Volunteers
- 4,800 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, DVT
Soft Robotic Sock Intervention for Robot-assisted Ankle-foot Mobility in Post-stroke Patients
Stroke is closely associated with high mortality among patients in hospitals and immobility leading development of deep vein thrombosis (DVT) leading to pulmonary embolism (PE) and Venous thromboembolism (VTE) and/or ankle joint…
- Conditions
- Stroke, DVT, Ankle Contracture
- Trial name
- NCT05491109
- Testing
- Venous Assistance and Contracture Management System (VACOM)
- Where
- Singapore
- Volunteers
- 19 people
- Sponsor
- National University Hospital, Singapore
Stroke
Comparison of Effectiveness of Virtual Reality With Mirror Therapy in Improving Motor Function of Upper Limb of Stroke Patients
The purpose of the study is to compare the effectiveness of virtual reality and mirror therapy in stroke patients. Different studies has been done to find out the best therapy for stroke patients.
- Trial name
- NCT05441228
- Testing
- Oculus Quest 2, Mirror therapy box
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Shifa Tameer-e-Millat University
Stroke, Ischaemic Stroke
Atrial Fibrillation Detected by ELR and Holter Recording, a Comparison in Patients With Ischemic Stroke or TIA
Purpose 1. To validate 2 -day loop recording ( R.Test Evolution 4 ) to 2 -day Holter recording (gold standard) for the detection of atrial fibrillation of ≥ 30 seconds duration in a consecutive population of patients with stroke…
- Conditions
- Stroke, Ischaemic Stroke, Atrial Fibrillation, Supra Ventricular Extra Systoles
- Trial name
- NCT02155907
- Where
- Denmark
- Volunteers
- 1,507 people
- Sponsor
- University of Aarhus
Moyamoya Disease, Intracranial Atherosclerotic Stroke
Moyamoya Disease Biomarkers in Patients With Intracranial Atherosclerotic Stroke
The aim of this study is to investigate the proportion of patients with moyamoya disease among the patients who were diagnosed as having intracranial atherosclerotic stroke.
- Conditions
- Moyamoya Disease, Intracranial Atherosclerotic Stroke, Intracranial Steno-occlusive Disease
- Trial name
- NCT02074111
- Where
- South Korea
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Ischemic Stroke
Reparative Therapy in Acute Ischemic Stroke With Allogenic Mesenchymal Stem Cells From Adipose Tissue, Safety Assessment, a Randomised, Double Blind Placebo Controlled Single Center Pilot Clinical Trial
Phase IIa clinical trial, pilot, single centre, prospective, randomized, double-blind, placebo-controlled, with sequential inclusion of patients
- Trial name
- AMASCIS-01 (NCT01678534)
- Testing
- Allogenic mesenchymal stem cells from adipose tissue
- Where
- Spain
- Volunteers
- 19 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Cerebrovascular Accident
Augmenting the Effects of Mirror Therapy for Stroke Rehabilitation by tDCS
This project is to evaluate and compare the impact of tDCS stimulation location on augmenting MT effects.
- Trial name
- NCT04655209
- Testing
- apply a-tDCS on the ipsilesional M1 followed by MT (M1-Seq), apply a-tDCS on the ipsilesional PMC followed by MT (PMC-Seq)
- Where
- 2 sites in Taiwan
- Volunteers
- 75 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke
Development of a Genomics-based Multimodal Prediction Model for Post-stroke Vascular Dementia
To collect large-scale multimodal data, including genomic information, neuroimaging, neurophysiological measures, cognitive assessments, and clinical characteristics from stroke survivors and healthy controls.
- Trial name
- NCT07660263
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Seyoung Shin
Stroke, Ischemic Stroke
Dietary Nitrate Supplements and Ischemic Stroke Recovery
This is a double-blind, randomized, placebo-controlled, pilot study. Participants will be randomized to receive either beetroot juice or a beetroot juice placebo, as a dietary supplement, for 30 days.
- Conditions
- Stroke, Ischemic Stroke, Cerebrovascular Accident
- Trial name
- NCT02838901
- Testing
- Beet it Beetroot juice
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Wake Forest University Health Sciences
Stroke, Stroke, Cardiovascular
EMG Control Assistance Virtual Reality Interface Coupled With Cerebellar-iTBS for Arm Recovery After Stroke (ERICA)
The investigators hypothesize that a myoelectric (EMG) controlled virtual reality (VR) interface allows for effective upper limb motor recovery of stroke patients.
- Trial name
- ERICA (NCT06911671)
- Testing
- Virtual Reality Interface + Cerebellar iTBS (c-iTBS), Physical Therapy
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Ischemic Stroke, Transient Ischemic Attack
Treat Stroke to Target
The aim of this study is the evaluation of two usual care strategies after stroke or TIA : achieved target LDL-C of 100 mg/dL (+/-10 mg/dL) or less than 70 mg/dL.
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Atherosclerotic Stenosis
- Trial name
- TST (NCT01252875)
- Testing
- Target : 100 mg/dL (+/-10 mg/dL), 70 mg/dL
- Where
- 2 sites in France
- Volunteers
- 2,873 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Postural; Defect
Spinal Straightness, Posture And Balance, Physical Performance And Energy Consumption In Individuals With Stroke
Patients diagnosed with ischemic or hemorrhagic stroke who applied to Kırıkkale University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation will be included in the study.
- Conditions
- Stroke, Postural; Defect, Energy Supply; Deficiency
- Trial name
- NCT06699381
- Testing
- use of spinal mouse, Brunnstrom's Hemiplegia Recovery Staging, The six minute walking test (6MWT)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kırıkkale University
Myocardial Infarction, Cerebrovascular Accident
Analyzing Gene Regions That May Interact With the Effectiveness of High Blood Pressure Drugs
High blood pressure is one of the most common health problems in the United States. There are many drug treatment options for high blood pressure, but these medications are not always effective.
- Conditions
- Myocardial Infarction, Cerebrovascular Accident, Death, Sudden, Cardiac
- Trial name
- NCT00573092
- Where
- United States
- Sponsor
- University of Washington
Stroke Sequelae
Therapeutic Effects of Robotic Exoskeleton-Assisted Gait Re-habilitation and Predictive Factors of Significant Improvements in Stroke Patients
Investigators aimed to examine the effectiveness of robotic exoskeleton-assisted gait training in stroke rehabilitation, and to determine predicting factors of significant improvements in post-stroke patients.
- Trial name
- NCT05825144
- Testing
- Robotic exoskeleton-assisted gait rehabilitation, Conventional rehabilitation
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taichung Veterans General Hospital
Stroke
A Rehabilitation Program Based on Daily Activities in Patients With Cerebrovascular Accident
Mixed qualitative and quantitative study, in two phases: Creation of a self-rehabilitation program based on people's daily living activities and designed with and for them.
- Trial name
- LARAQS (NCT05772663)
- Testing
- Personalized program of rehabilitation, Routine program of rehabilitation
- Where
- France
- Volunteers
- 158 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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