Clinical trials: Brain Stroke
Neurologic Disorder, Paralysis
EMPOWER Early Feasibility Study: Non-invasive BCI to Control a Wheelchair for People With Paralysis
Neuralis is an innovative assistive technology designed for individuals with severe neuromuscular conditions, enabling wheelchair control through EEG signals.
- Conditions
- Neurologic Disorder, Paralysis, Paralysis; Stroke, Amyotrophic Lateral Sclerosis
- Trial name
- NCT06169696
- Testing
- Intervention/Treatment
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Synaptrix Labs Inc.
Stroke
Thrombolysis in Pediatric Stroke (TIPS)
Thrombolysis in Pediatric Stroke (TIPS) is a five-year multi-center international safety and dose-finding study of intravenous (IV) tPA in children with acute ischemic stroke (AIS) to determine the maximal safe dose of…
- Trial name
- TIPS (NCT01591096)
- Testing
- Tissue plasminogen activator (Activase®)
- Where
- 15 sites in United States, Canada
- Volunteers
- 1 people
- Sponsor
- Seattle Children's Hospital
Atrial Fibrillation, Atrial Flutter
Combined Use of BIOTRONIK Home Monitoring and Predefined Anticoagulation to Reduce Stroke Risk
The IMPACT Study will investigate the potential clinical benefit of the combined use of BIOTRONIK Home Monitoring (HM) technology and a predefined anticoagulation plan compared to conventional device evaluation and…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Stroke, Embolism, Systemic Arterial
- Trial name
- IMPACT (NCT00559988)
- Testing
- Home Monitoring Guided OAC, Physician-Directed OAC
- Where
- 80 sites in United States, Australia and 4 more
- Volunteers
- 2,718 people
- Sponsor
- Biotronik, Inc.
Ischemic Stroke
Acute Effects of Thai Traditional Massage on Cerebrovascular Reactivity in Ischemic Stroke Patients
The investigators hypothesize that Acute Thai traditional massage will yield beneficial effects on cerebrovascular reactivity in ischemic stroke patients.
- Trial name
- NCT02270294
- Testing
- Thai traditional massage, No massage
- Where
- Thailand
- Volunteers
- 14 people
- Sponsor
- Chulalongkorn University
Stroke
Neurovascular Unit for Aged Patients With Geriatric Care and Evaluation of Factors Associated With Autonomy Loss
There are few neurovascular units (short stay and MRS (medical and rehabilitation service)) dedicated to the care of older people after a stroke in France and around the world.
- Trial name
- NUAGE (NCT07805694)
- Testing
- Not applicable- observational study
- Where
- France
- Volunteers
- 3,500 people
- Sponsor
- Hospices Civils de Lyon
Stroke
Peripheral Nerve Stimulation to Improve Upper Extremity Function After Severe Stroke
Subjects will receive non-invasive stimulation of nerves on their arm and intensive motor training of their arm. The timing of the stimulation in relation to the training will vary by group.
- Trial name
- NCT04576013
- Testing
- Peripheral nerve stimulation (PNS), Intensive upper extremity motor training
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Kentucky
Intracerebral Hemorrhage, Atrial Fibrillation
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
Primary Aim: To determine if apixaban is superior to aspirin for prevention of the composite outcome of any stroke (hemorrhagic or ischemic) or death from any cause in patients with recent ICH and atrial fibrillation (AF).
- Trial name
- ASPIRE (NCT03907046)
- Testing
- Apixaban, Aspirin
- Where
- 187 sites in United States
- Volunteers
- 700 people
- Sponsor
- Yale University
Ischemic Stroke, Sleep Apnea Syndromes
Pilot-Study for SAS Treatment in Acute Cerebral InfarctiOn: the PISTACIO Trial
Sleep Apnea Syndrome (SAS) is highly prevalent in acute stroke and it is related to worst outcome. We aim to assess if SAS treatment, started immediately after acute ischemic stroke, impacts infarct growing and clinical prognosis.
- Trial name
- PISTACIO (NCT04801069)
- Testing
- Nocturnal Ventilation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- SOS Attaque Cérébrale
Ischemic Stroke
Glyburide Advantage in Malignant Edema and Stroke Pilot
The primary objective of this study is to assess the feasibility of enrolling, evaluating, and treating with glyburide for injection severe anterior circulation ischemic stroke participants, whether or not treated with standard…
- Trial name
- GAMES-PILOT (NCT01268683)
- Testing
- Glyburide for Injection
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- Remedy Pharmaceuticals, Inc.
Intracerebral Hemorrhage
Safety of NXY-059 for the Treatment of Patients Who Have Suffered From a Stroke
This study will determine if NXY-059 is safe in patients with an acute stroke caused by bleeding in the central nervous system. The primary objective was to assess the safety and tolerability of NXY-059 compared to placebo.
- Trial name
- NCT00075959
- Testing
- NXY-059
- Where
- 64 sites in United States
- Volunteers
- 600 people
- Sponsor
- AstraZeneca
Remote Ischemic Conditioning
Dynamic Cerebral Autoregulation of Remote Ischemic Conditioning Combined With Intravenous Thrombolysis for Acute Ischemic Stroke
The purpose of this study is to determine the impact of remote ischemic conditioning on dynamic cerebral autoregulation in patients with acute ischemic stroke receiving intravenous thrombolysis.
- Trial name
- CARIC-IVT (NCT05125861)
- Testing
- remote ischemic conditioning
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Yi Yang
Stroke
Effects of Upper Limb Motor and Robotic Training Over Neuroplasticity and Function Capacity
The purpose of this study is to evaluate and compare the effects of upper limb training with Induced Constraint Therapy (ICT) or robotic therapy. No placebo therapy is used.
- Trial name
- NARLE1 (NCT02700061)
- Testing
- Robotic occupational therapy, Induced Constraint Therapy - ICT
- Where
- Brazil
- Volunteers
- 51 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke
Anti-platelet Precision Medicine to Prevent Stroke Early Progression and Recurrence (PRECISE)
This is a pragmatic, multi-center, non-interventional, non-randomized prospective observational study.
- Trial name
- NCT03701360
- Where
- South Korea
- Volunteers
- 1,199 people
- Sponsor
- Asan Medical Center
Atherosclerosis, Ischemia
Trial to Assess the Ocular Safety of Vorapaxar (SCH 530348) in Participants With Atherosclerosis (Study P05183)
This study is designed to evaluate the long-term ocular safety of SCH 530348 (vorapaxar) in participants with established atherosclerotic disease who are enrolled into the TRA 2°P - TIMI 50 Study (P04737) (NCT00526474).
- Conditions
- Atherosclerosis, Ischemia, Myocardial Infarction, Cerebrovascular Accident
- Trial name
- NCT00617123
- Testing
- Vorapaxar 2.5 mg
- Volunteers
- 258 people
- Sponsor
- Merck Sharp & Dohme LLC
Cerebrovascular Accident, Accidental Falls
Balance and Gait Characteristics to Predict Accidental Falls in Community-dwelling Stroke Elderly
Background: Accidental falls result in major physical and psychological morbidity in the elderly, especially stroke patients. To get optimal prevention of stroke falls, it is crucial to identify independent risk factors from…
- Trial name
- NCT01825486
- Testing
- accidental falls
- Where
- Taiwan
- Sponsor
- Changhua Christian Hospital
Stroke
Safety and Tolerability of BIII 890 in Patients With Acute Ischemic Stroke
The objective of this study is to assess the safety, tolerability and pharmacokinetic characteristics of BIII 890 after intravenous infusion in acute ischemic stroke patients.
- Trial name
- NCT02251197
- Testing
- BIII 890 CL
- Volunteers
- 97 people
- Sponsor
- Boehringer Ingelheim
Subacute Stroke, Acute Stroke
Feasibility of Video Gaming Technology for Arm Recovery Early Post-stroke
The investigators are investigating ways to incorporate new technologies that can enhance functional outcome after neurological insult into the patient recovery space.
- Trial name
- SMARTER (NCT06691880)
- Testing
- MindPod Dolphin VGT, Bimanual Arm Trainer VGT
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Johns Hopkins University
Stroke
Scandinavian Candesartan Acute Stroke Trial (SCAST)
The purpose of this trial is to assess whether the blood pressure lowering agent candesartan (an angiotensin receptor type 1 blocker) is effective when given to patients with acute stroke and elevated blood pressure.
- Trial name
- NCT00120003
- Testing
- Candesartan Cilexetil
- Where
- Norway
- Volunteers
- 2,500 people
- Sponsor
- Ullevaal University Hospital
Acute Ischemic Stroke
Effect of Human Urinary Kallidinogenase on Inflammatory Factors in Acute Ischemic Stroke (KIF-AIS)
The goal of this clinical trial is to explore the changes in the expression levels of inflammatory factors before and after the early treatment of Human Urinary Kallidinogen (HUK) in the acute ischemic stroke.
- Trial name
- NCT06696703
- Testing
- Human urinary kininogenase(HUK)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Transient Ischemic Attack, Thromboembolic Stroke
Carotid Artery Revascularization Using the Boston Scientific EPI Filter Wire EZ™ and the EndoTex™ NexStent™
The primary objective of this study is to demonstrate the safety of the NexStent for treatment of carotid artery lesions undergoing stenting with adjunctive use of the FilterWire distal embolic protection device.
- Conditions
- Transient Ischemic Attack, Thromboembolic Stroke, Stroke Prevention
- Trial name
- CABERNET (NCT00600327)
- Testing
- EndoTex™ NexStent™, Filter Wire EZ™
- Where
- 19 sites in United States, Argentina and 1 more
- Volunteers
- 488 people
- Sponsor
- Boston Scientific Corporation
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