Clinical trials: Brain Stroke
Stroke
Adaptive Optics (AO) Analysis of Retinal Arteries in Patients With Recent Stroke (STROKAO)
The eye has long been recognized as a window to pathological processes occurring in the brain. By imaging the vascular system of the retina scientific understanding and clinical practice have been improved for a wide range of…
- Trial name
- STROKAO (NCT04712747)
- Testing
- Ophthalmological examinations, Blood pressure measurement at rest
- Where
- France
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Hemiplegia, Stroke
Impact of Physiotherapy on Spasticity, Upper Limb Function, Daily Activities, and Kinesiophobia in Hemiplegic Patients
This study investigated the effects of rehabilitation exercises on spasticity levels, upper extremity functions, activities of daily living, and kinesiophobia in patients with hemiplegia following a stroke.
- Trial name
- NCT06542848
- Testing
- Physiotherapy and Rehabilitation Practices
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- University of Beykent
Stroke
Robot and tDCS Based Proprioceptive Rehabilitation After Stroke
Proprioceptive deficits are common following stroke, yet current evidence-based approaches for rehabilitating proprioception are limited.
- Trial name
- RoboStim (NCT03888326)
- Testing
- 1x1 anodal tDCS, Robotic Rehabilitation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Ischemia; Cerebrovascular, Cognitive Impairment
LA Improves the Prognosis of Patients With ICVD After Surgery
Ischemic cerebrovascular disease will cause serious harm to the life and safety of patients, and the treatment prognosis is poor.
- Trial name
- NCT05656209
- Testing
- Lactobacillus acidophilus
- Volunteers
- 236 people
- Sponsor
- Huaqiu Zhang
Sarcopenia, Stroke
A Novel/Common Approach for Temporalis Muscle Thickness Measurement
The aim of this study is to propose a new measurement point for temporal muscle thickness (TMT) that can be similarly localized in computerized tomography (CT) /magnetic resonance imaging (MRI) and ultrasonography (USG), and to…
- Trial name
- NCT05456399
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bozyaka Training and Research Hospital
Ischemic Stroke
Impact of Remote Ischemic Postconditioning on Autonomic Function in Stroke Patients
The purpose of this study is to determine whether remote ischemic postconditioning (RIPostC) initiates autonomic nervous system response and affects the prognosis in patients with acute ischemic stroke.
- Trial name
- IRAS (NCT02777099)
- Testing
- remote ischemic postconditioning
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Cancer- and Cancer Treatment-Related Conditions, Stroke
Studies on the Impact of Taste-aware Intelligent Analysis of Oral Nutritional Supplements
The goal of this observational study is to test the taste perception threshold and palatability interval of different populations and the difference in taste perception between tumor and stroke patients and healthy people by…
- Trial name
- NCT05651321
- Testing
- Samples materials of basic taste stimuli and enteral nutrition preparations
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Stroke
Effects of Mirror Therapy and Motor Imagery on Upper Limb Motor Functions in Middle Cerebral Artery Stroke
This study will compare mirror therapy (MT) with motor imagery (MI), each added to routine Bobath-based physical therapy, to assess upper limb motor function and functional independence in patients with subacute middle cerebral…
- Trial name
- NCT07902284
- Testing
- Mirror Therapy, Motor Imagery, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Stroke
Effects of Early Exercise in Patients With Moderate to Severe Stroke.
Purpose: to investigate the efficacy of early exercise in patients with moderate to severe stroke regarding functional outcome and walking ability.
- Trial name
- NCT04241952
- Testing
- Exercise
- Volunteers
- 52 people
- Sponsor
- Klas Sandberg
Hemispatial Neglect, Hemiplegia
The Effects of Offline Anosognosia For Spatial Neglect on Neglect Rehabilitation
Anosognosia for hemispatial neglect is an intriguing phenomenon characterized by decreased awareness of spatial deficits, common in patients with right hemisphere stroke.
- Conditions
- Hemispatial Neglect, Hemiplegia, Right Hemispheric Stroke, Anosognosia
- Trial name
- NCT05145855
- Testing
- Patient-tailored multimodal neglect rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Gazi University
Stroke, Knowledge, Attitudes, Practice
Effects of an Educational Intervention on Rehabilitation Clinicians' Practices for Health-related Outcomes After Stroke
The overall aim of this pilot study is to evaluate the feasibility of a study protocol for a future stepped wedge cluster randomized clinical trial (c-RCT) that will investigate the effects of an innovative KT intervention on 1)…
- Conditions
- Stroke, Knowledge, Attitudes, Practice, Physical Disability, Motor Skills Disorders
- Trial name
- NCT03807115
- Testing
- Implementation of stroke mobility guidelines
- Where
- 6 sites in Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- McGill University
Acute Ischemic Stroke
Extending the Time Window for Intravenous Tenecteplase in Patients With Distal Medium Vessel Occlusions Stroke
To assess the safety and efficacy of beyond time window TNK intravenous thrombolysis for distal Medium Vessel Occlusion (MeVO) related stroke in a prospective randomized clinical trial.
- Trial name
- NCT06559436
- Testing
- Intravenous thrombolysis, Standard medical management
- Where
- China
- Volunteers
- 560 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Stroke
Effects of Oropharyngeal Strengthening on Dysphagia in Patients Post-stroke
The overall goal of this randomized controlled pilot study is to characterize effects of SwallowSTRONG® Device-Facilitated Isometric Progressive Resistance Oropharyngeal (DF I-PRO) therapy in a dose response framework on…
- Trial name
- StrokeStrong (NCT02322411)
- Testing
- Isometric Progressive Resistance Oropharyngeal Therapy, Compensatory approaches
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Wisconsin, Madison
Stroke
Balance Training After Stroke - a Randomized, Controled Pilot Study
This pilot study is part of a master's thesis. In the rehabilitation of stroke patients should be compared whether individual balance training has a greater effect than group balance training.
- Trial name
- NCT03791671
- Testing
- individual balance training, group balance training
- Where
- Switzerland
- Volunteers
- 7 people
- Sponsor
- RehaClinic AG
Stroke
Mirror Therapy: Effects on Functional Recuperation of Severe Upper Limb Paresis After Stroke
After stroke, patients frequently suffer from arm or hand weakness. There are numerous rehabilitation methods to stimulate recovery, amongst which mirror therapy (MT).
- Trial name
- MT (NCT02949609)
- Testing
- Mirror Therapy, Control Therapy
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- University Hospital, Geneva
Neurologic Disorder, Paralysis
SWITCH II Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis
The Synchron Motor Neuroprosthesis (MNP) is intended to be used in subjects with severe motor impairment, unresponsive to medical or rehabilitative therapy and a persistent functioning motor cortex.
- Conditions
- Neurologic Disorder, Paralysis, Paralysis; Stroke, Amyotrophic Lateral Sclerosis
- Trial name
- NCT05041114
- Testing
- Motor Neuroprosthesis
- Where
- 3 sites in Australia
- Sponsor
- Synchron Medical, Inc.
Acute Stroke, Cerebral Ischemia
PMZ-1620 (Sovateltide) in Acute Ischemic Stroke Patients
This was a prospective, multicentric, randomized, double blind, parallel, saline controlled Phase II clinical study to compare the safety and efficacy of PMZ-1620 (INN: Sovateltide) therapy along with standard supportive care in…
- Trial name
- NCT04046484
- Testing
- Normal Saline along with standard treatment, PMZ-1620 along with standard treatment
- Where
- 7 sites in India
- Volunteers
- 40 people
- Sponsor
- Pharmazz, Inc.
Stroke, Subarachnoid Hemorrhage
Inhalatorial Sedation in Patient With Subarachnoid Hemorrhage (SAH) Versus Conventional Intravenous Sedation
Recent study has shown that inhalatory sedation is a practicable, effective and not risky method in Intensive Care Unit. Sevoflurane effect on cerebral system have been described in previous studies: it causes an increasing of…
- Trial name
- GAS-SAH (NCT00830843)
- Testing
- Propofol, Isoflurane
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Azienda Ospedaliera San Gerardo di Monza
Stroke
A Trial of Nature-based Post-stroke Fatigue Rehabilitation (NASTRU)
The aim of NASTRU was to examine whether ten weeks of nature-based rehabilitation, as add-on to standard management, could influence post-stroke fatigue (primary outcome), depression, work ability or functional outcome (secondary…
- Trial name
- NASTRU (NCT02435043)
- Testing
- Nature based rehabilitation, standard management after stroke
- Where
- Sweden
- Volunteers
- 101 people
- Sponsor
- Region Skane
Ischemic Stroke
The TESLA Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke
The primary objective of the trial is to establish the effectiveness of IAT (versus medical management) in patients with moderate-large infarcts (NCCT ASPECTS 2-5) at baseline, with adaptive enrichment to better define the upper…
- Trial name
- TESLA (NCT03805308)
- Testing
- Intra-arterial Therapy
- Where
- 43 sites in United States
- Volunteers
- 300 people
- Sponsor
- Mercy Health Ohio
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