Clinical trials: Brain Vascular Function
Stroke, Hand Function Impairment
Robotic-Assisted Training on Hand Function in Stroke
Stroke is a neurological deficit attributed to an acute focal injury of the central nervous system. A key component of stroke rehabilitation is improving upper limb function to reduce impairments and disabilities.
- Conditions
- Stroke, Hand Function Impairment, Fine Motor Skills
- Trial name
- NCT07701577
- Testing
- Robot-assisted training using the In motion robotic gym system, Conventional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Adly A Adam
Reversible Cerebrovascular Vasoconstriction Syndrome
Retinal Patterns in Reversible Cerebral Vasoconstriction Syndrome
Reversible cerebral vasoconstriction syndrome (RCVS) is a clinico radiological entity characterized by severe headaches (associated or not with neurological complications) during one to 3 weeks, associated with a characteristic…
- Trial name
- SVC-2R (NCT03204110)
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Chronic Stroke
Safety and Efficacy of Samsung GEMS-H Device Training in Sub-Acute and Chronic Stroke
A single-site, interventional, single-arm trial to evaluate the safety and efficacy on functional mobility following Samsung GEMS-H (Gait Enhancing and Motivating System - Hip) device training in participants with sub-acute and…
- Trial name
- NCT04285060
- Testing
- Samsung GEMS-H
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Samsung Electronics
Stroke
Effects of Computer Assisted Cognitive Rehabilitation on Patients With Stroke
This study aims to investigate the effects of computer assisted cognitive rehabilitation and conventional cognitive rehabilitation methods on patients' attention, quality of life and functional independence.
- Trial name
- NCT03890159
- Testing
- Computer Assited Cognitive rehabilitation, Conventional Cognitive Rehabilitation
- Volunteers
- 45 people
- Sponsor
- Ege University
Stroke, Cerebral Infarction
Platelet Hyperreactivity to Aspirin and Stroke
STUDY QUESTIONS What is the real prevalence of platelet "resistance" to aspirin during the acute phase of stroke and after 3 months, and 1 year, as measured using different platelet function tests? Do all methods measure similar…
- Conditions
- Stroke, Cerebral Infarction, Cardiovascular Diseases, Vascular Diseases
- Trial name
- PLARAS (NCT00766896)
- Testing
- Aspirin (platelet sensitive versus platelet hyperreactivity)
- Where
- Brazil
- Volunteers
- 203 people
- Sponsor
- University of Sao Paulo
Lower Extremity Dysfunction, Stroke
Sensitivity to Change of the Lower Extremity Functional Scale in Patients With Stroke
The purpose of this study was to investigate the reliability, construct validity, and sensitivity to change of the Lower Extremity Functional Scale (LEFS) in individuals affected by stroke.
- Trial name
- NCT01536990
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Mayo Clinic
Rehabilitation, Tenodesis, Stroke
Effectiveness of a Robot Assisted Tenodeis-grip Neurorehabilitation
In the proposed study, the investigators assumed that using robot assisted tenodesis-grip training providing high does assisted grip movement may do the effects on motor shaping and greater brain priming for hand paresis of the…
- Trial name
- NCT03713476
- Testing
- Motor task training
- Where
- Taiwan
- Volunteers
- 38 people
- Sponsor
- National Cheng-Kung University Hospital
Spinal Cord Injury, Stroke
Control of Unsupported Paraplegic Standing
The study will investigate the feasibility of using functional electrical stimulation (FES) of the calf muscles of paraplegic subjects to assist in posture stabilisation during standing.
- Trial name
- NCT00204113
- Testing
- Multi-purpose rehabilitation frame, Surface Functional Electrical Stimulation
- Where
- 2 sites in United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Glasgow
Fabry Disease
A Study of Migalastat in Fabry Disease
Fabry disease is a rare metabolic condition characterised by the widespread deposition of sphingolipids in multiple organ systems.
- Trial name
- GALAFAB (NCT03949920)
- Testing
- Migalastat
- Where
- 2 sites in United Kingdom
- Volunteers
- 21 people
- Sponsor
- Manchester University NHS Foundation Trust
Stroke
Does the Length of Hospital Stay for Rehabilitation Affect Functional Outcomes in Stroke Patients
The purpose of this study was to evaluate whether the length of hospital stay for rehabilitation affects functional outcomes of stroke patients.
- Trial name
- NCT04700982
- Testing
- Based on the length of hospital stay
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Baskent University
Subarachnoid Hemorrhage, Aneurysmal
Pilot Study of Ketamine Sedation for Aneurysmal Subarachnoid Hemorrhage
Aneurysmal subarachnoid hemorrhage (aSAH) is bleeding into the space between the brain and the tissues that surround the brain as a result of a ruptured aneurysm and is a type of stroke associated with high morbidity and…
- Trial name
- PENDULUM (NCT05032118)
- Testing
- Ketamine Hydrochloride, Propofol
- Sponsor
- Jenna L Leclerc MD, PhD
Stroke, Stroke, Ischemic
Ischemic Conditioning Improves Walking Function Post Stroke
This innovative study will address scientific and clinical areas relatively unexplored in chronic stroke that could lead to greater recovery of walking.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Cardiovascular
- Trial name
- NCT04038697
- Testing
- Ischemic Conditioning, Treadmill Training
- Where
- 2 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Stroke
Effectiveness of Robot-assisted Rehabilitation in Persons With Stroke
This study is to investigate the effects of robot-assisted hand with visual feedback intervention on cortical excitability, brain structure, spasiticity, gross and fine motor of upper limb and hand in individuals with stroke.
- Trial name
- NCT04002076
- Testing
- Robot-assisted hand combined with occupational therapy, Traditional occupational therapy
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Taipei Medical University Hospital
Stroke, Brain Infarction
Critical Periods After Stroke Study (CPASS)
To perform an exploratory single center randomized study that will form the basis for a larger scale, more definitive randomized clinical trial to determine the optimal time after stroke for intensive motor training.
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- CPASS (NCT02235974)
- Testing
- Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MedStar National Rehabilitation Network
Stroke
Cognitive Impact of Pomegranate Polyphenols Following Ischemic Stroke
The purpose of this study is to determine whether pomegranate supplements improve cognitive functioning following stroke.
- Trial name
- NCT02442804
- Testing
- POMx
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Loma Linda University
Stroke
The Effect Of Transcranial Magnetic Stimulation In Patients With Stroke
This study is aimed to investigate the effect of continuous theta burst stimulation (cTBS) and low frequency repetitive transcranial magnetic stimulation (rTMS) on upper extremity spasticity and functional recovery in patients…
- Trial name
- NCT04562415
- Testing
- Active Repetitive Transcranial Magnetic Stimulation Therapy, Active Continuous Theta Burst Stimulation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Cerebrovascular Accident
Ischemic Nerve Block to Improve Hand Function in Stroke Patients
This study will determine whether impaired hand function due to stroke can be improved by blocking nerve impulses to the unaffected arm.
- Trial name
- NCT00056706
- Testing
- Transient deafferentation
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Infarction
Human Umbilical Cord Mesenchymal Stem Cell Therapy (19#iSCLife®-CI) for Cerebral Infarction Patients in Convalescent Period.
This is a randomized, double-blind study. Human umbilical cord mesenchymal stem cells (hUC-MSC) will be treated on cerebral infarction patients, and evaluates their neurological function of convalescent period.
- Trial name
- NCT03176498
- Testing
- Allogeneic umbilical cord mesenchymal stem cell, Aspirin Enteric-coated Tablets & Atorvastatin Calcium
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sclnow Biotechnology Co., Ltd.
Stroke
Robot-Aided Assessment and Rehabilitation of Upper Extremity Function After Stroke
The purpose of this clinical trial is to investigate the efficacy of a hybrid-based rehabilitation program for the upper extremity(UE) combining the interventions- Functional Electrical Stimulation (FES) and Robotic…
- Trial name
- NCT05854485
- Testing
- REACH robotic training and multi-muscle Functional Electrical Stimulation (FES) group, Robot only group
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Maryland, Baltimore
Ischemic Stroke
Discovering Patterns in the Gut Microbiota Associated With the Risk of Stroke and the Outcome After a Stroke and Integration of These Data With Genomic Information to Find New Drug Targets and New Treatments to Improve Neurological Evolution and Functional Status of Stroke Patients.
The composition of the intestinal microbiota is associated with the risk of stroke and with post-stroke neurological evolution. At the same time, the genetics and epigenetics of each patient are associated with the composition of…
- Trial name
- MAESTRO (NCT04795687)
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau