Clinical trials: Brain Vascular Function
Hemiplegia, Lower Extremity Dysfunction
Lower Extremity Pressure Splints in HP
Hemiplegia (weakness or paralysis on one side of the body) often impacts the lower extremities, making it challenging for patients to walk or move their legs effectively.
- Conditions
- Hemiplegia, Lower Extremity Dysfunction, Stroke Rehabilitation
- Trial name
- NCT06965894
- Testing
- Johnston Pressure Splint, Rehabilitation Program
- Where
- Lebanon
- Volunteers
- 30 people
- Sponsor
- Istinye University
Respiratory Muscle, Pulmonary Function Test
Ultrasonographic Evaluation of Respiratory Muscles in Stroke Patients
Ultrasonographic evaluation of respiratory muscle thickness in stroke patients, determination of its correlation with pulmonary function test (PFT) , and the first evaluation method to determine respiratory rehabilitation goals…
- Trial name
- NCT05093491
- Testing
- Spirometry and ultrasonography in stroke group, Spirometry and ultrasonography in healthy group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Stroke
Muscle Tone Changes in Acute Stroke According to Brain Injury
The purpose of the study is to examine connections between muscle tones, strength and function after stroke.
- Trial name
- NCT01041560
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Jyväskylä Central Hospital
the Effect of Virtual Reality on Stroke Rehabilitation
Effect of Robotic Therapy on Upper Extremity With Stroke
The purpose of this study is to determine how adding virtual reality assisted robotic treatment to traditional rehabilitation affects stroke patients' pain levels, functional status, and daily living activities.After conventional…
- Trial name
- NCT05815823
- Testing
- robotic exercise therapy, conventional therapy
- Volunteers
- 40 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Cystic Fibrosis, Cystic Fibrosis-related Diabetes
Cardiac Structure and Function in Patients with Cystic Fibrosis
In a prospective observational cohort study (n = 100), the investigators aim to assess the correlation between cardiac biomarkers, advanced echocardiography and cystic fibrosis genotype and severity and determine whether these…
- Conditions
- Cystic Fibrosis, Cystic Fibrosis-related Diabetes, Cystic Fibrosis, Pulmonary, Cystic Fibrosis of Pancreas
- Trial name
- NCT06084468
- Where
- 2 sites in Denmark
- Volunteers
- 104 people
- Sponsor
- Herlev and Gentofte Hospital
Stroke
Observational Learning in Stroke Patients
This study will determine how people who have had a stroke learn to perform a movement by observation, as compared with people who have not had a stroke.
- Trial name
- NCT00083642
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Hemiparesis
Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke
This study uses functional magnetic resonance imaging to map neural activity throughout the central nervous system during a shoulder abduction task to characterize what motor pathways are being used post-stroke.
- Trial name
- NCT06598150
- Testing
- Shoulder Abduction
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Stroke
Impaired Interlimb Coordination During Locomotion in Individuals With Chronic Stroke: Contributors and Effect on Walking Function
Individuals with chronic stroke have long-term walking problems that limit community engagement and quality of life, lead to secondary disabilities, and increase healthcare costs and burden.
- Trial name
- NCT07006818
- Testing
- Direct current stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois at Chicago
Intracranial Aneurysm, Muscular Atrophy
Minipterional Versus Pterional Craniotomy
This randomized prospective study was designed to compare the clinical, functional and aesthetic results of two surgical techniques for microsurgical clipping of anterior circulation aneurysms
- Trial name
- NCT01872741
- Testing
- Minipterional craniotomy, Pterional craniotomy
- Volunteers
- 58 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke
Cross Education for Upper Extremity Motor Function and Strength in Stroke
Stroke is the leading cause of disability and mortality worldwide. The impact of stroke on the upper extremity functions is a common and important cause of long-term disability.
- Trial name
- NCT06522191
- Testing
- Physiotherapy Training (PT), Cross-Education Intervention, Control Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Istanbul University - Cerrahpasa
Acute Stroke
Body Composition and Acute Stroke
Body composition appears to be a prognostic factor for the severity and functional outcome of stroke patients. In this study the prognostic value of two bioimpedance parameters will be studied (skeletal mass index and phase…
- Trial name
- PREDISTROKE (NCT06589297)
- Testing
- Modified Rankin scale
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Stroke
Effect of Lower Limb Proprioceptive Neuromuscular Facilitation Combined With Core Stability Training Versus Proprioceptive Neuromuscular Facilitation Alone on Balance and Functional Mobility in Chronic Stroke Survivors
This randomized controlled trial compares lower limb proprioceptive neuromuscular facilitation (PNF) combined with core stability training versus lower limb PNF alone in chronic stroke survivors.
- Trial name
- NCT07887360
- Testing
- Lower Limb PNF Combined with Core Stability Training, Lower Limb PNF alone
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Ibadat International University, Islamabad
Brain Injuries, Acute, Brain Injuries, Traumatic
Antiseizure Medication in Seizure Networks at Early Acute Brain Injury
The goal of this clinical trial is to explore the effect of FDA-approved antiseizure drugs in the brain connectivity patterns of severe and moderate acute brain injury patients with suppression of consciousness.
- Conditions
- Brain Injuries, Acute, Brain Injuries, Traumatic, Brain Ischemia, Brain Hypoxia
- Trial name
- NCT06081283
- Testing
- Phenobarbital Sodium Injection, Levetiracetam, Lacosamide Injectable Product
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of North Carolina, Chapel Hill
Stroke
The Effects of Fresnel Prism Glasses on Visual Perception, Balance, Gait and Functional Independence in Post-Stroke Patients
This randomized controlled trial aims to evaluate the effects of Fresnel prism glasses on visual perception, balance, gait, and functional independence in post-stroke patients.
- Trial name
- NCT07308054
- Testing
- Fresnel Prism Glasse, Convetional physical therapy
- Volunteers
- 50 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Stroke
Personalized Post-Stroke Gait Rehabilitation Interventions
The objective of this study is to understand whether certain post-stroke patient subsets, identified from clinical, biomechanical, and neuromuscular characteristics, preferentially respond to different walking rehabilitation…
- Trial name
- NCT07212608
- Testing
- Soft robotic exosuit, Propulsion neuroprosthesis
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston University Charles River Campus
Aortic Valve Disease
Transcranial Doppler (TCD) Assessment During Early Anti-thrombotic Therapy After Bioprosthetic Aortic Valve Replacement
The purpose of this study is to determine if there is any difference in the counts of cerebral emboli and platelet function between two prophylactic treatments of thrombosis currently used at University of Ottawa Heart Institute…
- Trial name
- Tissue-Valve (NCT00465218)
- Testing
- Prophylaxis of Thrombosis after aortic valve replacement
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Chronic Stroke
Blood Flow Restriction and Transcutaneous Electrical Nerve Stimulation on Motor Function in Stroke
Stroke commonly results in persistent leg impairments that limit mobility and reduce quality of life. This study investigates whether combining low-intensity resistance training with blood flow restriction (LIRT-BFR) and…
- Trial name
- NCT06973590
- Testing
- Blood flow restriction (BFR), Transcutaneous electrical nerve stimulation (TENS), Low-intensity resistance training (LIRT)
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke/Brain Attack
Functional Efficiency of Self-sufficiency Test
The aim of this study is to design and validate new tool for evaluation of self-sufficiency in post-acute stroke patients. And further identify the factors influencing changes in the Functional Efficiency of Self-sufficiency Test…
- Trial name
- FEST (NCT06518460)
- Testing
- Functional Efficiency of Self-sufficiency Test
- Where
- Czechia
- Volunteers
- 164 people
- Sponsor
- Palacky University
Rehabilitation, Recovery of Function
Constraint-induced Movement Therapy to Improve Gait and Mobility of People With Chronic Stroke
The purpose of this single-subject, concurrent mixed methods study is to investigate the relationship between the effect of the CIMT protocol on gait and mobility and participants' and caregivers' expectations and perceptions…
- Conditions
- Rehabilitation, Recovery of Function, Stroke, Lower Extremity Paresis
- Trial name
- NCT03114046
- Testing
- Lower extremity Constraint-induced movement therapy(LE-CIMT)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Alabama at Birmingham
Acute Ischemic Stroke, Transient Ischemic Attack
Imaging and Serological Biomarkers of Autonomic Dysfunction After Ischemic Stroke
The goal of this observational study is to to investigate the prevalence and time course of autonomic dysfunction in acute ischemic stroke patients; to evaluate the influence of lesion location on autonomic dysfunction; to…
- Trial name
- ARIADNE (NCT06740942)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf