Clinical trials: Brain Waves
Cerebral Palsy (CP)
Effect of rESWT Session Frequency on Spasticity and Function Assessed by Sonoelastography in Children With Cerebral Palsy
Spasticity is a major contributor to functional limitations in children with cerebral palsy. Radial extracorporeal shock wave therapy (rESWT) has emerged as a non-invasive method for reducing spasticity; however, the optimal…
- Trial name
- CP-rESWT-FREQ (NCT07476690)
- Testing
- Real radial extracorporeal shock wave therapy (rESWT), Conventional physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Parkinson Disease
Ultrasound Shear Wave Elastography in Parkinson's Disease
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor symptoms including muscle rigidity as one of major motor symptoms affecting quality of life of Parkinson's disease patients, thus we aim…
- Trial name
- NCT06701318
- Testing
- Ultrasound shear wave elastography
- Volunteers
- 68 people
- Sponsor
- Assiut University
Brain Waves
Effects of Korean Red Ginseng Extract on Electrical Brain Activity in Elderly Subjects
A prospective, randomized, double blind, placebo-controlled study to determine if a hydroponically-cultivated red ginseng preparation is superior to conventionally grown ginseng and placebo for positively affecting electrical…
- Trial name
- NCT04167449
- Testing
- HRG80 Hydroponic Red Ginseng, Conventional White Ginseng
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- EuroPharma, Inc.
Gaucher Disease, Liver Fibrosis
Liver and the Spleen Stifness in Adult Patients With Gaucher's Disease Using Ultrasound Shear Wave Elastography
The investigated cohort will examine liver and spleen fibrosis in patients with Gaucher Disease(GD) by using Shear Wave Elastography- SWE to evaluation fibrosis of the tissue and to check the correlation of fibrosis with the…
- Conditions
- Gaucher Disease, Liver Fibrosis, Spleen; Fibrosis
- Trial name
- NCT03896607
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- HaEmek Medical Center, Israel
Healthy, Mild Cognitive Impairment
Does Acoustic Stimulation During Sleep Boost Slow Wave Sleep and Memory Performance?
With aging the amount of slow wave sleep decreases drastically and this disruption is markedly exaggerated in older adults suffering from mild cognitive impairment and Alzheimer's disease.
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT04277104
- Testing
- Closed loop acoustic stimulation
- Where
- Switzerland
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Bern
Ischemic Stroke, Arterial Stiffness
Pulse Wave Velocity and in Subacute Stroke Patients Following Rehabilitation
Currently, the literature regarding the relationship between Pulse Wave Velocity (PWV) and functional recovery, particularly of upper limb function, in patients with subacute stroke is still limited.
- Conditions
- Ischemic Stroke, Arterial Stiffness, Pulse Wave Velocity, Rehabilitation
- Trial name
- NCT06224517
- Testing
- Rehabilitation
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Subarachnoid Hemorrhage, Stroke
Brain Skull Deformation as a Non-invasive Intracranial Pressure (ICP) Measure
Background: Although placement of an intra-cerebral catheter remains the gold standard method for measuring intracranial pressure (ICP), there are several limitations to the method.
- Conditions
- Subarachnoid Hemorrhage, Stroke, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- NCT05121155
- Testing
- ICP wave morphology comparison between a non-invasive (Brain4care) and a invasive method
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Federal University of São Paulo
Stroke Gait Rehabilitation
The Effectiveness of Laser and Extracorporeal Shock Wave Therapy in Resolving Ankle Muscle Spasm in Stroke Patients.
Stroke is one of the leading causes of long-term disability worldwide. Spasticity (muscle spasm) is a common and disabling consequence of stroke.
- Trial name
- spasticity (NCT07364110)
- Testing
- Rehabilitation Protocol, Extracorporeal Shock Wave Therapy (ESWT), High-Intensity Laser Therapy (HILT)
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Necmettin Erbakan University
Epilepsy
Neonatal Brain Waves After Electrocoagulation
Electrocoagulation effect of neonatal brain waves after cesarean section
- Trial name
- NCT00396773
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Spastic Quadriplegia, Cerebral Palsy (CP)
Focused Versus Radial Extracorporeal Shock Wave Therapy on Gastrocnemius Spasticity in Children With Spastic Quadriplegic Cerebral Palsy
The goal of this pilot randomized controlled trial is to compare the effectiveness of focused extracorporeal shockwave therapy (ESWT) versus radial ESWT on gastrocnemius spasticity in children with spastic quadriplegic cerebral…
- Conditions
- Spastic Quadriplegia, Cerebral Palsy (CP), Gastrocnemius Muscle
- Trial name
- NCT07894003
- Testing
- Focused Extracorporeal Shock Wave Therapy, Radial Extracorporeal Shock Wave Therapy
- Where
- Indonesia
- Volunteers
- 16 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Fabry Disease, Amyloidosis
Substudy (NCT04456582): Noninvasive Assessment of Myocardial Stiffness by 2D-SWE Ultrasound Technique (Two-dimensional Shear Wave Elastography) in Patients With Amyloidosis and Fabry Disease.
Introduction: Heart failure with preserved systolic function encompasses several different diseases, but which have diastolic dysfunction and its components in common: myocardial stiffness and altered relaxation.
- Trial name
- FABRY (NCT04893889)
- Testing
- Shear-wave elastography
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Epilepsy
SeizEAR Safety Study
Determine the safety and feasibility of an in-ear device to measure seizures or suspected seizures compared to the standard scalp-based electroencephalogram (EEG).
- Trial name
- NCT07088835
- Testing
- SeizEAR
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Major Depressive Disorder (MDD), Hypovitaminosis D
Effect of Vitamin D Supplementation on Brain Waves in Female Major Depressive Disorder Patients With Hypovitaminosis D
Major Depressive Disorder (MDD) is a common mood disorder characterized by persistent sadness, loss of interest and cognitive impairment.
- Trial name
- NCT07579078
- Testing
- Dietary vitamin D
- Where
- Bangladesh
- Volunteers
- 34 people
- Sponsor
- Bangladesh Medical University
Spinal Cord Injuries (SCI), Spinal Cord Injury
Clinical Testing of Invasive Spinal Cord Stimulation and Evaluation of Its Physiological Effects Using the Electroencephalography
The aim of the study is to identify the specific characteristics of brain network dysfunctions and assess the recovery of their functionality through the recording of resting-state electroencephalography (EEG) during…
- Trial name
- NCT06725836
- Testing
- Implantation of electrodes into the epidural space for spinal cord stimulation, Selection of the optimal spinal cord stimulation program for spastic syndrome suppression, Selection of the optimal spinal cord stimulation program for volitional motor control
- Where
- 3 sites in Russia
- Volunteers
- 35 people
- Sponsor
- Artur Biktimirov
Dementia, Alzheimer s Disease
Brain Wave Informed Non-invasive Brain Stimulation: Improving Neural Networks of Working Memory in Dementia: a Proof-of-concept Study
Working memory helps us hold information for a short time so one can think and make decisions. It keeps thoughts on track. As one gets older, working memory gets weaker.
- Trial name
- BWIBS-WM (NCT07673770)
- Testing
- EEG-triggered TMS
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Carotid Atherosclerosis
Shear Wave Elastography for Carotid Atherosclerotic Plaques
The goal of this prospective diagnostic accuracy cohort study is to compare the accuracy of carotid atherosclerotic plaques stiffness assessed by shear wave elastography (SWE) with greyscale median values (GSM), magnetic…
- Trial name
- NCT06214429
- Testing
- Vascular Ultrasound, Shear Wave Elastography, Greyscale Median
- Where
- Brazil
- Volunteers
- 43 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Spasticity, Cerebral Palsy
Shockwaves Therapy and Botulinum Toxin for the Treatment of Spasticity in Patients With Cerebral Palsy. A Cross Over RCT
Spasticity is a motor disorder that can affect the lower limbs in up to 75% patients with cerebral palsy, having a significantly effect on their mobility and quality of life.
- Trial name
- NCT02400619
- Testing
- shock waves, Botulinum Toxin Type A
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Xavi Vidal Novellas
Alzheimer Disease, Early Onset
A Pivotal Study of LIPUS-Brain in Patients With Early Alzheimer's Disease
This study is a multicenter, randomized, double-blinded, placebo-controlled Phase 3 study comparing LIPUS-Brain transcranial low-intensity pulsed-wave ultrasound device to placebo in patients with Early Alzheimer's Disease.
- Trial name
- NCT05983575
- Testing
- LIPUS-Brain
- Where
- 19 sites in Japan
- Volunteers
- 220 people
- Sponsor
- Sound Wave Innovation CO., LTD.
Benign Epilepsy With Centro Temporal Spikes (BECTS), Atypical Benign Partial Epilepsy (ABPE)
Sleep Related Memory Consolidation in Children With Age Related Focal Epilepsy.
Age related focal epilepsies in children encompasses, according to the ILAE criteria, benign epilepsy with centro temporal spikes (BECTS), atypical benign partial epilepsy (ABPE) and epileptic encephalopathy with continuous spike…
- Conditions
- Benign Epilepsy With Centro Temporal Spikes (BECTS), Atypical Benign Partial Epilepsy (ABPE), Epileptic Encephalopathy With Continuous Spike and Waves During Sleep (ECSWS)
- Trial name
- EPIMEM (NCT03865771)
- Testing
- Neuropsychological testing, Neuropsychological procedure, Video EEG and polysomnography
- Where
- 2 sites in France
- Volunteers
- 95 people
- Sponsor
- University Hospital, Strasbourg, France
Carotid Artery Plaque
Carotid Artery Plaque Vulnerability Assessment Using Ultrafast Ultrasound Techniques
Objective: To explore the association between spatio-temporal blood flow velocities (peak systole and end-diastole at prior-stenosis, at maximum stenosis, and post-stenosis) and carotid plaque vulnerability defined by histology…
- Trial name
- CAP-VALUE (NCT05218421)
- Testing
- Carotid ultrasound, Biospecimen collection and examination, Blood sample collection
- Where
- 2 sites in Netherlands
- Volunteers
- 70 people
- Sponsor
- Radboud University Medical Center