Clinical trials: Brain to Brain Communication
Stroke, Emotionality
Piloting the Attention Training Technique for Post-Stroke Emotionalism
The aim of this mutli-phasic systematic case series is to explore if the Attention Training Technique (ATT) can improve symptoms of Post Stroke Emotionalism.
- Conditions
- Stroke, Emotionality, Pseudobulbar Affect, Lability Emotional
- Trial name
- NCT06457126
- Testing
- Attention Training Technique
- Where
- 2 sites in United Kingdom
- Volunteers
- 14 people
- Sponsor
- University of Manchester
Alzheimer Disease, Mild Cognitive Impairment
Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorders
The primary objective of the study is to evaluate the feasibility of eliciting continuous narrative speech in different neurodegenerative and psychiatric indications, using remote, self-administered speech tasks, as measured by…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Dementia With Lewy Bodies, Dementia, Vascular
- Trial name
- RHAPSODY (NCT04939818)
- Where
- 2 sites in United Kingdom
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Novoic Limited
Dementia, Dementia, Vascular
Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers
The goal of this clinical trial is to improve communication among clinicians, patients with memory problems, and their family members.
- Conditions
- Dementia, Dementia, Vascular, Mixed Dementias, Alzheimer Disease
- Trial name
- PICSI-M (NCT05596760)
- Testing
- Jumpstart Guide
- Where
- 3 sites in United States
- Volunteers
- 1,802 people
- Sponsor
- University of Washington
Lung Cancer
The Role of the Vagus Nerve in Tumor-to-Brain Communication in Lung Cancer Patients
the aim of this study is to measure brain metabolism in patients with lung cancer.FDG uptake in the brain in patients with malignant tumors will be compared to the amount of tracer activity found in patients who have benign…
- Trial name
- NCT00397124
- Testing
- PET/CT imaging
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Rambam Health Care Campus
Palliative Care, Communication
Timely End-of-Life Communication to Parents of Children With Brain Tumors
A national priority for health care providers is to initiate early communication about palliative and end-of-life care (PC/EOL) for children with a poor prognosis.
- Trial name
- NCT01170000
- Where
- 4 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The Foundation for Barnes-Jewish Hospital
Stroke, Psychological Distress
Wellbeing After Stroke (WAterS): Supporting Adjustment and Wellbeing After Stroke
Stroke survivors face a range of mental health challenges adjusting post-stroke. There is a lack of treatment options and clinical psychologist workforce to deliver support.
- Conditions
- Stroke, Psychological Distress, Cognitive Dysfunction, Communication Disorders
- Trial name
- WAterS (NCT04655937)
- Testing
- Acceptance and Commitment Therapy
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Manchester
Stroke
Return to Work With Post Stroke Communication Disorders
Approximately a quarter of stroke survivors are of working age, and it is well-known that disabilities caused by stroke can lead to difficulties returning to work.
- Trial name
- ConQueSt (NCT05500144)
- Testing
- Not applicable- no intervention administered
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- NHS Grampian
Aphasia, Non-fluent Aphasia
Combining tDCS and CILT in Non-fluent Aphasia
The long-term goal of this work is to determine if combining a highly intensive, task-specific behavioral language intervention with modulation of the efferent cerebellar-cortical pathway using transcranial direct current…
- Conditions
- Aphasia, Non-fluent Aphasia, Stroke, Brain Injuries
- Trial name
- NCT05561400
- Testing
- tDCS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Minnesota
Aphasia, Cerebrovascular Stroke
Transcranial Magnetic Stimulation to Improve Speech in Aphasia
The purpose of this study is to examine whether repetitive transcranial magnetic stimulation (rTMS) can be used to improve speech in chronic stroke patients with aphasia. Aphasia patients can have problems with speech production.
- Trial name
- NCT00608582
- Testing
- Transcranial Magnetic Stimulation, Repetitive
- Where
- 3 sites in United States
- Volunteers
- 63 people
- Sponsor
- Boston University
Cerebellar Function, Transcranial Magnetic Stimulation
Enhanced Recovery After Surgery Using TMS on Cerebellar Language Area for Brain Tumor Patients
At present, the incidence of language dysfunction in patients with brain language area tumor in the first month after operation was 20%-40%.
- Conditions
- Cerebellar Function, Transcranial Magnetic Stimulation, Language Disorders
- Trial name
- NCT03974659
- Testing
- Transcranial magnetic stimulation
- Where
- 2 sites in China
- Volunteers
- 106 people
- Sponsor
- Huashan Hospital
Mental Health Wellness 1, Parent-Child Relations
BRIGHT Coaching Program for Families
Children with, or at elevated risk for, brain-based developmental disabilities can experience lifelong consequences and challenges throughout their development.
- Conditions
- Mental Health Wellness 1, Parent-Child Relations, Child Developmental Delay, Parenting
- Trial name
- NCT03880383
- Testing
- Coaching, Online parent education, Online peer support
- Where
- 4 sites in Canada
- Volunteers
- 306 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Stroke
Fall Risk Intervention for Stroke
After stroke, falling is a common problem. Falls can lead to injury, as well as fear of future falls. It is important to try to prevent falls from happening after stroke.
- Trial name
- FRISKI (NCT07349030)
- Testing
- Fall Prevention Intervention, Active Control
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- MGH Institute of Health Professions
Encephalopathy, Birth Defect
Clinical Utility of Pediatric Whole Exome Sequencing
The investigator aims to examine the clinical utility of WES, including assessment of a variety of clinical outcomes in undiagnosed pediatric cases.
- Conditions
- Encephalopathy, Birth Defect, Intellectual Disability, Multiple Congenital Anomaly
- Trial name
- NCT03525431
- Testing
- Whole Exome Sequencing
- Where
- 4 sites in United States
- Volunteers
- 529 people
- Sponsor
- University of California, San Francisco
Aphasia, Stroke
HD-tDCS for Phonological Impairment in Aphasia
This study will investigate the effects of mild electrical stimulation in conjunction with speech therapy for people with post-stroke aphasia to enhance language recovery.
- Trial name
- NCT06010030
- Testing
- Targeted Transcranial Direct Current Stimulation, Speech Therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Medical College of Wisconsin
Alzheimer Disease, Preclinical Alzheimer's Disease
Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping - FUTURE Extension
The primary objective of the study is to evaluate whether a set of algorithms analysing acoustic and linguistic patterns of speech, can predict change in Preclinical Alzheimer's Clinical Composite with semantic processing (PACC5)…
- Conditions
- Alzheimer Disease, Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Alzheimer's Disease (Incl Subtypes)
- Trial name
- FUTURE-US (NCT04951284)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Novoic Limited
Multiple Sclerosis, Stroke
From Clinic to Community: An Information and Communication Technology (ICT) Home-Based Exercise Training System for Translating Clinical Findings
The specific aim of the study in our example is to conduct a feasibility translational home-based exercise trial established in the LEADERS (R2) project with the TExt-ME tele-exercise training system for participants with…
- Trial name
- TExT-ME (NCT03108950)
- Testing
- Movement to Music
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Alabama at Birmingham
Attention Deficit Hyperactivity Disorder, Asthma
Using an Online Patient Monitoring System to Improve Care for Children With Chronic Conditions
TriVox Health is an online system designed to make it easy for healthcare providers to monitor patients' disease symptoms and functioning over time and in between in-person visits (http://www.youtube.com/watch?v=VR1vcbx0Ef4).
- Conditions
- Attention Deficit Hyperactivity Disorder, Asthma, Autism Spectrum Disorder, Depression
- Trial name
- TriVoxHealth (NCT02097355)
- Testing
- TriVox for clinical care
- Where
- United States
- Volunteers
- 946 people
- Sponsor
- Boston Children's Hospital
Brain to Brain Communication
Linked Outcomes in Various EEG-Hyperscanning Setups
The goal of this observational study is to investigate how brains of healthy controls respond when they interact with their romantic partner compared to when they interact with a stranger.
- Trial name
- LOVEH (NCT07385027)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Alzheimer's Disease (AD), Dementia
Negotiation Training for Family Caregivers of People With Alzheimer's Disease
Family caregivers of people living with Alzheimer's disease and related dementias often experience conflicts and communication challenges when coordinating care, making decisions, and interacting with family members and…
- Conditions
- Alzheimer's Disease (AD), Dementia, Cognitive Impairment
- Trial name
- NCT07859540
- Testing
- NegotiAge, PlanYourLifespan
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Down Syndrome
Non-Invasive Brain Stimulation to Improve Language in Down Syndrome.
Down syndrome (DS) is associated with cognitive deficits, caused by alterations in neuroplasticity and synaptic transmission. Non-invasive brain stimulation techniques, such as transcranial direct current stimulation (tDCS), can…
- Trial name
- NCT07044804
- Testing
- Active Group (Active Anodal tDCS to the left IFG or Cathodal tDCS to the left IFG)
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Floriana Costanzo