Clinical trials: Breast
Breast Cancer Metastatic
Evaluation of Somatostatin Receptor Expression in PET 68Ga-DOTATOC in Patients Followed for Metastatic Breast Cancer
DOTABREAST: Evaluation of Somatostatin Receptor Expression in PET 68Ga-DOTATOC in Patients Followed for Metastatic Breast Cancer This is a prospective, monocentric, non-controlled, non-randomized, open-label, interventional study.
- Trial name
- DOTABREAST (NCT06611891)
- Testing
- 68Ga-DOTATOC
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Grenoble
Breast Cancer
Hand and Foot Bath for Taxane-Induced Peripheral Neurotoxicity
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and dose-limiting toxicity of taxane-based agents, with an incidence of 57%-83%.
- Trial name
- NCT07344974
- Testing
- Traditional Chinese medicine (TCM) hand and foot baths, Methylcobalamin (methylB12)
- Volunteers
- 78 people
- Sponsor
- Peking University Cancer Hospital & Institute
Breast Neoplasms
Mobile Health (mHealth) Black Women With Breast Cancer
This research study will test whether a series of video clips with breast cancer information improves knowledge of breast cancer, breast cancer treatment and living with breast cancer.
- Trial name
- NCT02463474
- Testing
- mHealth Intervention
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Florida
Adipose Tissue Atrophy, Deformity of Reconstructed Breast
Effect of N-Acetylcysteine on Autologous Fat Graft Survival
A single-centre triple-blind study looking at the addition of NAC to tumescent solution for liposuction and fat grafting in healthy patient volunteers already undergoing bilateral breast reduction.
- Conditions
- Adipose Tissue Atrophy, Deformity of Reconstructed Breast, Graft Loss
- Trial name
- NCT02788292
- Testing
- Acetylcysteine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Breast Cancer, Muscle Strength
Effectiveness of PNF Training for Improving for Muscle Strength, Function, and Pain After Axillary Lymph Node Dissection
Breast cancer is the most common type of cancer affecting women of all ages worldwide. Advanced and comprehensive treatment options have increased survival rate and life expectancy, necessitating a focus on the complications of…
- Trial name
- NCT05288036
- Testing
- Proprioceptive Neuromuscular Rehabilitation group, Progressive Resistance Exercise Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Cancer, Solid Tumor
Exploring Cancer-Associated Thromboembolism Prognosis Biomarkers and Polymorphisms
This study aims to assess biomarkers and their related polymorphisms in the context of cancer-associated thromboembolism, with a particular focus on their interaction with the immune system.
- Conditions
- Cancer, Solid Tumor, Thromboembolism, Cardiovascular Diseases
- Trial name
- CAT_PB (NCT06065592)
- Testing
- Palbociclib, Rivaroxaban, SNP
- Where
- 2 sites in Lebanon
- Volunteers
- 500 people
- Sponsor
- Lebanese University
Breast-milk
Breast-milk Enema Administration to Stimulate Passage of Meconium
Lack of passage of meconium in preterm infants delays feeding advancement and may represent a risk factor for necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP).
- Trial name
- BEAM (NCT07661992)
- Testing
- breast milk
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wake Forest University Health Sciences
Breast Cancer, Anxiety
Study of Exercise to Manage Distress During Breast Screening
The breast cancer screening and diagnostic period is associated with heightened symptoms of anxiety and depression. Physical exercise has been found to effectively decrease these symptoms in healthy and diseased populations.
- Conditions
- Breast Cancer, Anxiety, Depression
- Trial name
- NCT02468050
- Testing
- Moderate intensity exercise training, Self Management of exercise
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- University of Western Ontario, Canada
Breast Cancer
Neoadjuvant Therapy With Herceptin and Taxol for Breast Cancer
The purpose of this study is to determine the effectiveness and safety of administering Herceptin in combination with Taxol (paclitaxel) in the treatment of women with HER2-positive, early stage breast cancer prior to surgery.
- Trial name
- NCT00136539
- Testing
- Herceptin, Taxol, Adriamycin
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Harold J. Burstein, MD, PhD
Breast Cancer
Study of the Effects of Chemotherapy on Memory and Other Mental Functions in Women With Breast Cancer
Many breast cancer patients treated with chemotherapy complain of problems with concentration and memory. This has been referred to as chemo fog.
- Trial name
- NCT00260975
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Breast Cancer
A Study of ZN-c5 in Participants With Breast Cancer
This is a Phase 1 open-label, multicenter study to evaluate biomarkers for ZN-c5 in subjects with breast cancer
- Trial name
- NCT04176757
- Testing
- ZN-c5
- Where
- 10 sites in United States, Australia and 1 more
- Volunteers
- 35 people
- Sponsor
- Zeno Alpha Inc.
Breast Cancer
Evaluation of Needle Core Biopsy of Axillary Sentinel Lymph Node in Breast Cancer
The purpose of the study is to determine if it is possible to identify and perform a needle biopsy of the sentinel lymph node. The investigators hope to identify breast cancer cells in the lymph nodes under the arm without making…
- Trial name
- ENCASe (NCT02046057)
- Testing
- PNB of SLN
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Loma Linda University
Breast Cancer
Neoadjuvant Therapy in Clinical Stage I-III HER2-positive Breast Cancer.
Neoadjuvant therapy is given to breast cancer patients whose cancers are relatively large or have spread to lymph nodes or both.
- Trial name
- NCT02789657
- Testing
- paclitaxel, Trastuzumab, Pertuzumab
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Brown University
Breast Cancer
Application of CT-Linac-Based "All-in-One" One-Stop Radiotherapy in Breast Cancer
This study aims to evaluate and report the clinical adverse events and dosimetric parameters in breast cancer patients undergoing an "all-in-one (AIO)" one-stop, fully automated radiotherapy workflow.
- Trial name
- NCT07776301
- Testing
- Radiotherapy procedure
- Where
- China
- Volunteers
- 225 people
- Sponsor
- Fudan University
Breast Cancer, Colo-rectal Cancer
The French E3N Prospective Cohort Study
The French E3N cohort was initiated in 1990 to investigate the risk factors associated with cancer and other major non-communicable diseases in women.
- Conditions
- Breast Cancer, Colo-rectal Cancer, Parkinson Disease, Asthma
- Trial name
- E3N (NCT03285230)
- Where
- France
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Breast Cancer
A Non-interventional Prospective Study of Early HER2-negative High-risk Breast Cancer and BRCA1/2 Mutations Prevalence in RussiA
(Neo)adjuvant treatment approaches and outcomes
- Trial name
- ERA (NCT05939128)
- Where
- 19 sites in Russia
- Volunteers
- 625 people
- Sponsor
- AstraZeneca
Outpatient Breast Surgery, Mastopexy
Serratus Plane Block for Postoperative Pain Control
This is a randomized, double-blinded, placebo-controlled trial of serratus plane blocks in subjects undergoing outpatient unilateral or bilateral breast surgery.
- Conditions
- Outpatient Breast Surgery, Mastopexy, Augmentation, Revision
- Trial name
- NCT02865928
- Testing
- Bupivicaine HCl, Normal Saline
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Northwell Health
Breast Cancer, Triple Negative Breast Cancer
Neoadjuvant Nab-paclitaxel in Triple-negative or HER2-positive Breast Cancer
To evaluate the efficacy and safety of nab-paclitaxel combined with carboplatin for Chinese patients with triple-negative and HER2-positive breast cancer in the neoadjuvant setting.
- Conditions
- Breast Cancer, Triple Negative Breast Cancer, HER2-positive Breast Cancer
- Trial name
- NeoPATH (NCT03907800)
- Testing
- Nab-paclitaxel, Carboplatin, Herceptin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Ruijin Hospital
Breast Cancer
Docetaxel Alone or in Combination With Vaccine to Treat Breast Cancer
This study will test whether giving a combination of a vaccine together with docetaxel is more effective against breast cancer than docetaxel alone.
- Trial name
- NCT00179309
- Testing
- Docetaxel, PANVAC-V, PANVAC-F
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer Metastatic, Sentinel Lymph Node
Rapid Assessment of Sentinel Lymph Node Metastasis Status Using a Pan-CK-targeting NIR-II Fluorescent Probe in Breast Cancer
Breast malignant tumors are a serious threat to women's health, and the current treatment for breast malignant tumors is still dominated by surgery, but the problems faced by patients after surgery such as edema and tumor…
- Conditions
- Breast Cancer Metastatic, Sentinel Lymph Node, Sentinel Lymph Node Biopsy (SLNB), Metastasis
- Trial name
- NIR-II (NCT07154563)
- Testing
- NIR-II probe (i.e ICG-CK) incubation solution
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yunnan Cancer Hospital