Clinical trials: Breast Cancer, Breast Neoplasms
Breast Cancer, HER2-negative Breast Cancer
Neoadjuvant Treatment of Locally-advanced Breast Cancer Patients With Ribociclib and Letrozole
Patients with locally advanced (stage III) breast cancer (LABC) are characterized by a significantly worse prognosis compared to patients with primarily operable breast cancer.
- Conditions
- Breast Cancer, HER2-negative Breast Cancer, ER-positive Breast Cancer, Locally Advanced Breast Cancer
- Trial name
- NEOLETRIB (NCT05163106)
- Testing
- Letrozole 2.5mg oral tablet; Ribociclib 600mg oral tablet, Goserelin
- Where
- Norway
- Volunteers
- 85 people
- Sponsor
- University Hospital, Akershus
Metastatic Breast Cancer to the Brain
18F-FLT-PET Imaging of the Brain in Patients With Metastatic Breast Cancer to the Brain Treated With Whole Brain Radiation Therapy With or Without Sorafenib: Comparison With MR Imaging of the Brain
The purpose of this study is to compare two different imaging methods to examine the response of brain metastases to WBRT. These two imaging methods will take pictures of the brain using : 1) a positron emission tomography (PET)…
- Trial name
- NCT01621906
- Testing
- 18F-FLT-PET Imaging
- Where
- 6 sites in United States
- Volunteers
- 17 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer Metastatic
A Study to Evaluate the Efficacy and Safety of Margetuximab Plus Chemotherapy in the Treatment of Chinese Patients With HER2+ MBC
This is a randomized, open-label, multi-center, Phase II clinical study to evaluate the efficacy and safety of margetuximab plus chemotherapy compared with trastuzumab plus chemotherapy in Chinese patients (Mainland, Hong Kong…
- Trial name
- NCT04262804
- Testing
- Margetuximab, Trastuzumab, Chosen Chemotherapy (Capecitabine)
- Where
- Taiwan
- Volunteers
- 123 people
- Sponsor
- Zai Lab (Shanghai) Co., Ltd.
Pleural Metastases, Breast Cancer
Heated Chemotherapy for Cancers That Have Spread to the Chest Cavity
Cancers that have spread to the inner lining of the chest are classified as Stage IV and bear a poor prognosis. Surgery is rarely an option, with palliative chemotherapy and/or radiation therapy the only treatment options.
- Conditions
- Pleural Metastases, Breast Cancer, Colon Cancer, Ovarian Cancer
- Trial name
- NCT01163552
- Testing
- Surgical debulking and Intrathoracic Hyperthermic Chemotherapy
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Breast Cancer
Acupressure for Cancer-Related Fatigue
This study develops and pilot tests the efficacy of a home-based, self-administered acupressure intervention in improving cancer-related fatigue (proximal outcome), and physical functioning and other quality of life outcomes…
- Trial name
- NCT03091647
- Testing
- acupressure intervention, usual care
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Georgetown University
Breast Carcinoma
Demographic , Clinicopathological Characteristics and Survival of Breast Cancer
The investigators will retrospectively study the demographic , clinicopathological characteristics and survival of breast cancer patients admitted to Assiut University hospital from the year 2015 to 2019
- Trial name
- NCT04316247
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Breast Cancer
Effect of a Natural Health Product on Urinary Estrogen Metabolites
The purpose of this study is to determine if a supplemental formula can beneficially alter the ratio of urinary estrogen metabolites.
- Trial name
- NCT01089049
- Testing
- FemMED Breast Health Formula
- Where
- Canada
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
Breast Cancer
Blood Levels of Tumor Cells in Predicting Response in Patients Receiving First-Line Chemotherapy for Stage IV Breast Cancer
RATIONALE: Measuring blood levels of tumor cells in patients with breast cancer may help doctors predict how patients will respond to treatment.
- Trial name
- NCT00898014
- Testing
- fluorescence in situ hybridization, immunologic technique, laboratory biomarker analysis
- Where
- France
- Volunteers
- 216 people
- Sponsor
- Institut Curie
Mammary Cancer, Lymphoma
The Efficacy and Safety of PEG-rhG-CSF in Neutropenia After Chemotherapy
The purpose of the trail is to evaluate the efficacy and safety of PEG-rhG-CSF in primary prophylaxis and secondary prophylaxis of neutropenia after chemotherapy.
- Conditions
- Mammary Cancer, Lymphoma, Bone Tumour, Gynecological Tumors
- Trial name
- NCT02905916
- Testing
- PEG-rhG-CSF
- Where
- China
- Volunteers
- 217 people
- Sponsor
- Peking University
Breast Cancer
Comparison of Paravertebral Block With General Anesthesia in Patients Undergoing Breast Cancer Surgery
The purpose of this project is to determine if there is a difference between paravertebral block and general anesthesia in terms of time to discharge from the Post-Anesthesia Care Unit and pain level in patients undergoing…
- Trial name
- NCT00645138
- Testing
- Paravertebral Block, General Anesthesia
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Weill Medical College of Cornell University
Breast Cancer, Quality of Life
Breast Cancer Self-Management Mobile Care Application Intervention in the Quality of Life
The aim of this study was to investigate the quality of life (QoL) for women with breast cancer in Taiwan after using the BCSMS App.
- Trial name
- NCT04174248
- Testing
- BCSMS App
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- National Yang Ming Chiao Tung University
Breast Cancer, Breast Neoplasm
Development of Assist Tool for Breast Examination Using the Principle of Ultrasonic Sensor
The accuracy of breast examinations and ultrasonography performed clinically to detect breast mass varies greatly depending on the physician\'s skill level, and the accuracy of breast examinations by non-experts is…
- Conditions
- Breast Cancer, Breast Neoplasm, Artificial Intelligence, Ultrasonography
- Trial name
- NCT06255808
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital
Breast Cancer Female
Radioguided Occult Lesion Localisation by Indocyanine Green
Breast cancer is the most common cancer in women. It is the main cause of cancer deaths among women. The incidence of non-palpable tumors is estimated at 60%.
- Trial name
- ROLL-1 (NCT03313908)
- Testing
- detection of the tumor lesion
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma
177Lu-DOTATATE for the Treatment of Stage IV or Recurrent Breast Cancer
This phase II trial investigates how well 177Lu-DOTATATE works in treating patients with breast cancer that is stage IV or has come back (recurrent).
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Recurrent Breast Carcinoma
- Trial name
- NCT04529044
- Testing
- Biopsy, Biospecimen Collection, Computed Tomography
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- OHSU Knight Cancer Institute
Breast Cancer
ABX Plus Cisplatin Versus Gemcitabine Plus Cisplatin in Triple Negative Breast Cancer (TNBC)
ABX Plus Cisplatin Versus Gemcitabine Plus Cisplatin in Triple Negative Breast Cancer (TNBC)
- Trial name
- TNBC (NCT02546934)
- Testing
- ABX, cisplatin, Gemcitabine, Cisplatin
- Where
- China
- Volunteers
- 254 people
- Sponsor
- Fudan University
Breast Cancer
S0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as doxorubicin, cyclophosphamide, and paclitaxel, use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00070564
- Testing
- pegfilgrastim, AC regimen, cyclophosphamide
- Where
- 542 sites in United States, Canada and 1 more
- Volunteers
- 3,294 people
- Sponsor
- SWOG Cancer Research Network
Invasive Breast Cancer, Breast Cancer
Comparison of Intra-operative Radiotherapy With Post-operative Radiotherapy for Women With Early Breast Cancer
The purpose of this study is to evaluate whether a single fraction of radiotherapy given intra-operatively and targeted to the tissues at the highest risk of local recurrence is equivalent to standard post-operative external beam…
- Trial name
- TARGIT (NCT00983684)
- Testing
- Intrabeam, Post-operative radiotherapy
- Where
- United Kingdom
- Volunteers
- 3,451 people
- Sponsor
- University College, London
Metastatic Breast Cancer
Changes in Phenotype and Genotype of Breast Cancers During the Metastatic Process and Optimization of Therapeutic Targeting (ESOPE)
The primary objective is to compare the phenotype and genotype of the primary tumor with those of its metastases in order to optimize the treatment of metastatic disease, in patients presenting with first metastatic progression…
- Trial name
- NCT01956552
- Testing
- biopsy or cytopuncture
- Where
- 6 sites in France
- Volunteers
- 130 people
- Sponsor
- Institut Curie
Triple Negative Breast Cancer, Clear Cell Renal Cell Carcinoma
Study of BDC-3042 as Single Agent and in Combination With Cemiplimab in Patients With Advanced Malignancies
A first-in-human study using BDC-3042 as a single agent and in combination with cemiplimab in patients with advanced malignancies
- Conditions
- Triple Negative Breast Cancer, Clear Cell Renal Cell Carcinoma, Ovarian Cancer, Head and Neck Cancer
- Trial name
- NCT06052852
- Testing
- BDC-3042, Cemiplimab
- Where
- 6 sites in United States
- Volunteers
- 17 people
- Sponsor
- Bolt Biotherapeutics, Inc.
Breast Cancer
Study of Breast Cancer Shrinkage Modes After Neoadjuvant Chemotherapy With Whole-mount Serial Sections and Three-dimensional Pathological and MRI Reconstruction
The main clinical goal of NAC is to down-stage the primary tumor for BCS,yet BCS after NAC has been associated with significantly higher ipsilateral breast tumor recurrences.The accuracy of breast tumor excision in BCS can…
- Trial name
- BCSMANC (NCT01917578)
- Testing
- Ultrasound, CNB, BCS, Modified Radical Mastectomy
- Where
- China
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Shandong Cancer Hospital and Institute
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