Clinical trials: Breast Cancer Risk Factors
Advanced/Metastatic NSCLC, Advanced/Metastatic HER2-negative Breast Cancer
A Study Assessing Risk Factors for Oral Mucositis/Stomatitis and Ocular Surface Events in NSCLC and Breast Cancer
This study will identify risk factors for oral mucositis/stomatitis and ocular surface events (OSE) in patients with advanced/metastatic non-small cell lung cancer (NSCLC) and advanced/metastatic human epidermal growth factor…
- Trial name
- NCT06686602
- Testing
- No drug
- Where
- United States
- Volunteers
- 13,759 people
- Sponsor
- Daiichi Sankyo
Breast Cancer
The Effect of Aromatase Inhibitors on Cardiovascular Risk Factors in Women With Breast Cancer
This study explores how aromatase inhibitor therapy affects risk factors for heart disease in postmenopausal women with breast cancer.
- Trial name
- Silhouette (NCT01080170)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Metabolic Disturbance, Sedentary Behavior
Multiple Risk Factor Intervention Trial in Breast Cancer Survivors
This study aims to produce new evidence on the efficacy of exercise and diet for cardiometabolic risk reduction in BC survivors.
- Conditions
- Metabolic Disturbance, Sedentary Behavior, Breast Cancer Female
- Trial name
- MsFITBC (NCT06454864)
- Testing
- Guidelines-based healthy eating, Guidelines-based physical activity, Stretching exercise
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- University of Toronto
Breast Cancer, Aromatase Inhibitors
Prevalence and Risk Factors for Pain and Related Adverse Reactions Among Breast Cancer Survivors on Aromatase Inhibitors
We obtained the occurrence of pain sensation, pain mood, sleep, etc. during endocrine therapy in breast cancer patients through telephone follow-up, and analyzed risk factors through artificial intelligence
- Conditions
- Breast Cancer, Aromatase Inhibitors, Endocrine Therapy, Pain
- Trial name
- NCT05628077
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Peking University People's Hospital
Breast Cancer
Genes and Other Risk Factors for Second Primary Breast Cancer in Women With Breast Cancer and Their Female Family Members and Friends
RATIONALE: Studying samples of blood, urine, and tumor tissue in the laboratory from patients with cancer and their female relatives and friends may help doctors learn more about changes that occur in DNA and identify biomarkers…
- Trial name
- NCT00896818
- Testing
- DNA analysis, genetic linkage analysis, loss of heterozygosity analysis
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cancer Research UK
Breast Cancer
Dalpicilib-Enhanced vs. Standard Endocrine Therapy in ER+ HER2- Early Breast Cancer
This study aims to conduct a randomized controlled clinical trial to compare the efficacy and safety of dalpicilib combined with endocrine therapy versus standard endocrine therapy in ER-positive, HER2-negative, lymph…
- Trial name
- NCT06637150
- Testing
- Dalpicilib, endocrine therapy
- Where
- China
- Volunteers
- 1,388 people
- Sponsor
- Fudan University
Cardiomyopathy Due to Drug, Breast Cancer
2D Speckle-tracking Echocardiography in Chemotherapy-induced Cardiomyopathy With Cardiovascular Risk Factors
The aims of this study is to evaluate the role of 2D speckle-tracking echocardiography in diagnosis chemotherapy related left ventricular dysfunction in breast cancer patients with cardiovascular risks
- Conditions
- Cardiomyopathy Due to Drug, Breast Cancer, Cardiovascular Risk Factor
- Trial name
- NCT04547465
- Testing
- Echocardiography
- Where
- Vietnam
- Volunteers
- 300 people
- Sponsor
- Gia Dinh People Hospital
Colon Cancer, Breast Cancer
An Integrated Genomic Approach to Assess Genetic Risk and Drug Sensitivity
National multicenter prospective study, involving the enrollment of approximately 1,500 patients with ovarian cancer, 1,500 patients with breast cancer, and 1,000 patients with colorectal cancer.
- Conditions
- Colon Cancer, Breast Cancer, Ovarian Cancer, Genetic Risk Factors
- Trial name
- GERSOM (NCT07555639)
- Testing
- Genomic profile
- Where
- Italy
- Volunteers
- 4,000 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Breast Neoplasms, Lipid Profile
Chemotherapy-induced Lipid Profile Changes in Women With Early Breast Cancer
Detection of changes in the lipid profile in early-stage breast cancer patients undergoing neoadjuvant or adjuvant chemotherapy with doxorubicin, cyclophosphamide, and paclitaxel.
- Conditions
- Breast Neoplasms, Lipid Profile, Dyslipidemia
- Trial name
- NCT06958783
- Testing
- Blood lipid monitoring in breast cancer patients during chemotherapy
- Where
- Slovakia
- Volunteers
- 56 people
- Sponsor
- Cancer center Stefan Kukura Hospital Michalovce
Breast Cancer, Obesity
Effects of Mediterranean Diet and Naltrexone/Bupropion Treatment in Obese Breast Cancer Patients
Obesity among breast cancer survivors is known to be associated with recurrence and other co-morbidities. However, there have been no studies on weight reduction program combining diet and anti-obesity drug for obese breast…
- Conditions
- Breast Cancer, Obesity, Overweight
- Trial name
- NCT03581630
- Testing
- naltrexone/bupropion, Mediterranean Diet
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Chemotherapy-induced Febrile Neutropenia
Study Investigating How Physicians Assess the Risk of Patients Developing Febrile Neutropenia During Chemotherapy.
This is a prospective observational study investigating how physicians assess the risk of febrile neutropenia (FN) developing in patients who will receive chemotherapy.
- Trial name
- NCT01813721
- Where
- 90 sites in Australia, Austria and 9 more
- Volunteers
- 1,007 people
- Sponsor
- Amgen
Unilateral Breast Cancer
Prevalence of Lymphedema in Valle Del Cauca, Colombia.
This is an epidemiological cross-sectional study aiming to determine the prevalence of lymphedema and the incidence of risk factors in patients diagnosed with unilateral breast cancer in a cohort from 2008 to 2020 in a…
- Trial name
- NCT04987424
- Testing
- Development and validation of Lymphedema levels diagnostic
- Where
- Colombia
- Volunteers
- 367 people
- Sponsor
- Grupo de investigación C.E.R
Breast Cancer, Breast Cancer Mortality
Influence of Lifestyle, Inflammatory Biomarkers, and Genetic Factors on Long-term Breast Cancer Prognosis
The MARIEplus study is a prospective cohort of breast cancer patients recruited into the MARIE (Mamma Carcinoma Risk factor InvEstigation) study, a population-based case-control study of breast cancer conducted in two German…
- Conditions
- Breast Cancer, Breast Cancer Mortality, Breast Cancer Survival, Postmenopausal Breast Cancer
- Trial name
- NCT03401034
- Volunteers
- 3,813 people
- Sponsor
- German Cancer Research Center
Breast Neoplasm, Primary Prevention
Project Breast47: Effect of an Educational Intervention
Breast cancer is the most frequently diagnosed malignant tumor in women. In 2018, in Spain, the estimated incidence was 101/100,000 women.
- Conditions
- Breast Neoplasm, Primary Prevention, Risk Factors, Telemedicine
- Trial name
- Breast47 (NCT05267171)
- Testing
- Web access
- Where
- Spain
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Breast Cancer
MRI Background Parenchymal Enhancement as a Risk Factor for Breast Cancer: The IMAGINg and Epidemiology (IMAGINE) Study
The purpose of the study is to view what normal breast tissue looks like on an MRI and mammogram to help determine how it may affect the risk of developing breast cancer.
- Trial name
- NCT02301767
- Where
- 7 sites in United States
- Volunteers
- 2,187 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer, Breast Reconstruction
Implant-based Breast Reconstruction in Post-bariatric Women - a Registry-based National Study
The goal of this national registry-based study is to investigate the prevalence of reconstructive breast surgery and risk factors for surgical complications in women who have had weight loss surgery previously.
- Conditions
- Breast Cancer, Breast Reconstruction, Bariatric Surgery, Breast Implant
- Trial name
- NCT07059104
- Testing
- Breast augmentation, Breast reconstruction after mastectomy
- Where
- Sweden
- Volunteers
- 20,000 people
- Sponsor
- Vastra Gotaland Region
Breast Cancer Patients
Study of CYP2C19 and ALDH3A1 Polymorphisms in Breast Cancer Patients
Genetic polymorphisms of metabolic enzymes may influence the metabolism of Doxorubicin-Cyclophosphamide regimen in breast cancer patients. the investigators want to 1.
- Trial name
- NCT04581967
- Testing
- polymorphism analysis, Doxorubicin-Cyclophosphamide regimen
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Damanhour University
Breast Cancer
Exercise in Breast Cancer Survivors
The purpose of this study is to compare the effects of aerobic exercise to usual care in women treated with chemotherapy and radiation therapy for non-metastatic breast cancer
- Trial name
- NCT04307407
- Testing
- Aerobic Exercise
- Where
- Norway
- Volunteers
- 210 people
- Sponsor
- Norwegian School of Sport Sciences
Breast Cancer, Persistent Pain
Persistent Pain After Breast Cancer Treatment (PPBCT) - Risk Factors and Pathophysiological Mechanisms
The study is a prospective cohort study following breast cancer patients from before surgery to one year after. The aims of the study are to determine risk factors that predispose to the development of persistent pain.
- Conditions
- Breast Cancer, Persistent Pain, Lymphedema, Neuropathic Pain
- Trial name
- NCT01523132
- Where
- Denmark
- Volunteers
- 545 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Breast Neoplasms, Breast Cancer
Paclitaxel-induced Polyneuropathy in Breast Cancer: Early Detection, Risk Factors, Quality of Life and Lifestyle Outcomes
This is a single center prospective observational cohort study that aims to: examine and identify possible risk and susceptibility factors for the incidence and progression of chemotherapy-induced polyneuropathy (CIPN) in female…
- Conditions
- Breast Neoplasms, Breast Cancer, Early-stage Breast Cancer, Non-Metastatic Breast Carcinoma
- Trial name
- CIPN-REBECCA (NCT06052345)
- Testing
- Garmin smartwatch, REBECCA Mobile application, REBECCA PC plug-in
- Where
- Sweden
- Sponsor
- Theodoros Foukakis