Clinical trials: Breast Cancer Screening, open to volunteers
Cancer Risk, Breast Cancer Risk
Mirai-MRI: Validation of AI Models for Breast Cancer Risk
This is a multi-center, single arm trial to evaluate the cancer detection rate of supplemental screening magnetic resonance imaging (MRI) in participants who are high-risk by Mirai-MRI assessment.
- Trial name
- NCT07121972
- Testing
- Magnetic resonance imaging (MRI), Artificial Intelligence (AI)
- Where
- 4 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Metastatic Breast Cancer
AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.
This program initially aims to recruit 1300 breast cancer patients from a large number of hospitals across Europe. Eligible patients are those who are 18 or older, either female or male, and who have not received more than 1 type…
- Trial name
- AURORA (NCT02102165)
- Testing
- metastatic lesion biopsy
- Where
- 52 sites in Belgium, Germany and 8 more
- Volunteers
- 1,000 people
- Sponsor
- Jules Bordet Institute
Geriatric Assessment, Adjuvant Drug Therapy
Aspects of Adjuvant CDK4/6 Inhibitors in Older Breast Cancer Patients - Focusing on Geriatric Screening
Older breast cancer patients should not be categorically excluded from adjuvant therapies, including the recommended CDK4/6 inhibitors (CDK4/6i) administered in combination with endocrine therapy.
- Conditions
- Geriatric Assessment, Adjuvant Drug Therapy, Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Trial name
- FUTURE (NCT07273357)
- Where
- 5 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Region Jönköping County
Breast Neoplasms
CT-AI Breast Cancer Opportunistic Screening Health Examination Study
This study evaluates the clinical utility of a locked chest CT artificial intelligence model for opportunistic breast cancer screening among women undergoing health examinations.
- Trial name
- NCT07809698
- Testing
- CT-AI-assisted breast cancer screening
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Breast Cancer Screening, Colon Cancer Screening
Bundled Cancer Screening and Genetic Services Navigation
The goal of this study is to test bundled familial cancer risk assessment + multicancer (colorectal + breast) vs. single (breast) cancer navigation, using a wait list control for colorectal cancer screening referral and…
- Conditions
- Breast Cancer Screening, Colon Cancer Screening, Genetics Predisposition
- Trial name
- NCT07228000
- Testing
- Breast cancer screening navigation, Multicancer screening navigation, Usual care genetics referral
- Where
- 2 sites in United States
- Volunteers
- 820 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Breast Cancer
Identification of Breast Cancer in Breath Samples Using Trained Detection Dogs
The goal of this study is to find out whether a system that uses trained detection dogs and artificial intelligence (AI) can identify breast cancer from a person's breath.
- Trial name
- PINK (NCT07038785)
- Testing
- Breath test
- Where
- 6 sites in United States, Israel
- Volunteers
- 1,204 people, healthy volunteers welcome
- Sponsor
- SpotitEarly
Breast Cancer
VisR Ultrasound for Noninvasively Interrogating Stromal Collagen Organization in Women as a Breast Cancer Biomarker: Evaluation of Anisotropy in Cancer Patients
Purpose: This study will evaluate how measurements of tissue stiffness, viscosity, and anisotropy using non-invasive ultrasound imaging correlate with breast tumor malignancy and response to chemotherapy.
- Trial name
- NCT06878547
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Breast Benign, Malignant Neoplasm of Breast
Low-field MRI for Breast Cancer Screening
This research study wants to learn more about improving the attainable image quality for ultra-low field MRI of the breast using new data acquisition methods(also called MRI pulse sequences) and image reconstruction algorithms.
- Conditions
- Breast Benign, Malignant Neoplasm of Breast, Breast Malignant Tumor
- Trial name
- NCT05486520
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Breast Cancer, Lung Cancer (Diagnosis)
Building on Trust: Navigating Preventive Lung, Breast, and Prostate Cancer Screenings at Community Resource Spots
To evaluate a community-based outreach initiative for screening, diagnosis, and treatment of breast, lung, and prostate cancers in underserved adults using the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM)…
- Conditions
- Breast Cancer, Lung Cancer (Diagnosis), Prostate Cancer
- Trial name
- NCT07231159
- Testing
- referral for definitive diagnosis based on their cancer screening results, Engagement
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Lymphedema
Prospective Screening for Breast Cancer-related Lymphedema
The primary objectives of this study are twofold: 1) to detect and determine the level of symptoms, functional disability, and changes in quality of life that breast cancer patients experience from changes in their arms during…
- Trial name
- NCT01521741
- Testing
- Breast Cancer-Related Lymphedema Screening
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer Screening, Cervical Cancer Screening
Community Gateway to Health Study
The goal of this study is to evaluate the impact of a multi-level intervention on cancer prevention and social determinants of health outcomes.
- Conditions
- Breast Cancer Screening, Cervical Cancer Screening, Colon Cancer Screening, Tobacco Cessation
- Trial name
- NCT07592793
- Testing
- Tools and Training for Cancer Control, Enhancing Social Capital and Civic Engagement
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Breast Cancer
Optimising Mammography Screening Accuracy With Blood-based Biomarkers
The project aims to investigate whether breast cancer screening can be improved using blood tests, thereby reducing the number of unnecessary clinical mammographies.
- Trial name
- OPTIMA (NCT07049822)
- Where
- 2 sites in Denmark
- Volunteers
- 1,200 people
- Sponsor
- Vejle Hospital
Brain Cancer, Breast Cancer
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
This is an observational case-control study to train and validate a genome-wide methylome enrichment platform to detect multiple cancer types and to differentiate amongst cancer types.
- Conditions
- Brain Cancer, Breast Cancer, Bladder Cancer, Cervical Cancer
- Trial name
- CAMPERR (NCT05366881)
- Where
- 17 sites in United States
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Adela, Inc
Breast Cancer, Breast Cancer Female
SNAPS Breast Cancer Patient Study Breast Cancer Patients
Differential immunogenomic signatures from peripheral blood CD14 (phagocytic) and CD2 (non-phagocytic) cells have been associated with multiple cancers and disease states.
- Trial name
- NCT05370300
- Testing
- Blood test
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Immunis.AI
Cervical Cancer, Endometrial Cancer
Specimen and Data Study for Ovarian Cancer Early Detection and Prevention
RATIONALE: To improve strategies for detection and prevention of early-stage disease. PURPOSE: This research study is collecting specimens and data to develop better methods for early detection and prevention of ovarian cancer…
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Hereditary Breast/Ovarian Cancer (brca1, brca2)
- Trial name
- NCT00005095
- Testing
- Ca-125, screening questionnaire administration, Surgery
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Northwestern University
HER2-negative Early Breast Cancer
Neoadjuvant Therapy Study Guided by Drug Screening in Vitro for Human Epidermal Growth Factor Receptor 2 (HER2) Negative Early Breast Cancer Patients
Neoadjuvant treatment is an important treatment for early breast cancer patients. Patients with triple negative subtype who achieved pCR after neoadjuvant treatment would have longer survival.
- Trial name
- NCT04836156
- Testing
- neoadjuvant chemotherapy upon in vitro PTC drug sensitivity screening for triple negative breast cancer, neoadjuvant chemotherapy upon in vitro PTC drug sensitivity screening for luminal like breast cancer
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Peking University People's Hospital
Breast Cancer Detection, Breast Cancer
Screening and the Future of Enhanced MRI for Early Breast Cancer Detection
This study aims to recruit women aged 45 years in the Netherlands to participate in a one-time breast MRI screening examination and to evaluate their motivation for participation as well as the impact of screening on their…
- Conditions
- Breast Cancer Detection, Breast Cancer, Screening Strategy
- Trial name
- SAFE-MRI (NCT07878377)
- Testing
- Breast MRI Screening, Questionnaires
- Volunteers
- 2,628 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Breast Cancer Detection, Breast Neoplasm
Molecular Breast Imaging (MBI)-Guided Biopsy
The goal of this pilot clinical trial is to demonstrate supplemental screening MBI (molecular breast imaging) in women with dense breasts.
- Conditions
- Breast Cancer Detection, Breast Neoplasm, Molecular Imaging, Biopsy
- Trial name
- MBI-GB-Pilot (NCT07114679)
- Testing
- Molecular Breast Imaging, MBI-guided biopsy
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Smart Breast Corp.
Breast Cancer
Contrast-enhanced Mammography in Women With a Personal History of Breast Cancer and Dense Breast Tissue: Benefit?
This study aims to assess the effectiveness of Contrast-Enhanced Mammography (CEM)as an alternative to traditional ultrasound for breast cancer screening in women with dense breasts and a personal history of breast cancer.
- Trial name
- CEM (NCT06993246)
- Testing
- Contrast-Enhanced Mammography (CEM)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Jean Seely
Cervical Cancer Screening
Breast Cancer-Related Approach for Increasing Cervical Cancer Screening
The primary objective of this clinical trial is to assess cervical cancer screening participation among under-screened women invited through organized breast cancer screening programs in Switzerland.
- Trial name
- BRAICS (NCT07171658)
- Testing
- Sensitization to Cervical Cancer (CC) screening, Home-based HPV self-sampling
- Where
- Switzerland
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Jessica Di Vincenzo Sormani