Clinical trials: Breast Cancer Surgery Pain
Post-surgical Pain, Pain, Chronic
Intercostobrachial Nerve Sparing to Reduce Post-Surgical Pain
Sacrifice of the intercostobrachial nerve (ICBN) during surgery is associated with development of persistent post-surgical pain (PPSP), which affects up to 60% of breast cancer surgery patients.
- Conditions
- Post-surgical Pain, Pain, Chronic, Intercostal Pain, Breast Cancer
- Trial name
- INSPIRE (NCT03421522)
- Testing
- ICBN preservation surgery
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
Anesthesia, Analgesia
Pectoral Nerve Block II and Erector Spine Plane Block in Breast Cancer Surgery
This study evaluates the analgesic effects of pectoralis nerve block (PECS II) and erector spinae plane block (ESP) in patients having segmental mastectomy and sentinel lymph node biopsy (SLNB).
- Conditions
- Anesthesia, Analgesia, Acute Pain, Chronic Pain
- Trial name
- NCT04135157
- Testing
- Pectoralis nerve block II, Erector spine plane block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ondokuz Mayıs University
Nerve Blocks, Breast Surgery
Continuous Pectoral Nerve Block in Breast Cancer Surgery
The purpose of the study is to evaluate the effect of continuous pectoral nerve block on postoperative analgesia consumption in breast cancer surgery.
- Conditions
- Nerve Blocks, Breast Surgery, Postoperative Pain
- Trial name
- NCT04036370
- Testing
- PECS group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Antalya Training and Research Hospital
Postoperative Analgesia, Hand Strength
Long-term Outcomes of Breast Cancer Patients After Wound Infiltration Analgesia
In the study that was conducted from 05.01.2009 - 31.12.2012. 120 patients were examined. By drawing random numbers, the patients were randomized into 3 groups for postoperative analgesia: 1. Diclofenac 2 mg/kg/day - control, 2.
- Conditions
- Postoperative Analgesia, Hand Strength, Health Related Quality of Life, Chronic Shoulder Pain
- Trial name
- NCT05829707
- Testing
- Diclofenac Sodium, Levobupivacaine bolus analgesia, Levobupivacaine PCA group
- Volunteers
- 120 people
- Sponsor
- Osijek University Hospital
Breast Surgery
ER-One: A Double-blind Trial of Erector Spinae Block (ESP) Versus Paravertebral Block (PVB) Before Breast Cancer Surgery
The block (ESP or PVB) will be performed preoperatively in the recovery room under standard monitoring. After setting a peripheral venous access, patient will be installed on lateral decubitus position on the opposite side of the…
- Trial name
- ER-One (NCT04827030)
- Testing
- Ropivacaïne Hydrochloride by Erector Spinae block, Ropivacaïne Hydrochloride by Paravertebral block
- Where
- 5 sites in France
- Volunteers
- 292 people
- Sponsor
- Institut Curie
Breast Cancer Surgery, Breast Conserving Surgery
Erector Spinae Plane Block vs. PECS I-II Blocks After Breast-conserving Surgery
The goal of this study is to compare the analgesic effects of ESPB and PECS II blocks in patients undergoing BCS. The main question it aims to answer is: Whether these two different block procedures will create a difference in…
- Conditions
- Breast Cancer Surgery, Breast Conserving Surgery, Erector Spinae Plane Block, Pectoral Nerve (PECS) Block
- Trial name
- NCT06758765
- Testing
- Erector Spinae Plane Block, Pectoral Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Istanbul Saglik Bilimleri University
Breast Neoplasms, Pain
Regional Anesthesia in Breast Surgery
There is a trend that breast surgery can be done with peripheral nerve blockade and intravenous sedation, which reduces the side effects of general anesthesia such as nausea and vomiting, intubation discomfort and postoperative…
- Conditions
- Breast Neoplasms, Pain, Analgesia, Regional Anesthesia
- Trial name
- NCT04629612
- Testing
- Regional anesthesia
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Acute Pain, Chronic Pain
Ketamine as Adjunctive Analgesic With Bupivacaine in Paravertebral Analgesia for Breast Cancer Surgery
This study aims to investigate the safety and the analgesic efficacy of adding Ketamine to bupivacaine 0.25% in thoracic PVB in patients undergoing modified radical mastectomy.
- Trial name
- NCT02462681
- Testing
- paravertebral block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Breast Cancer, Pain, Chronic
Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery
The goal of this clinical trial is to is to compare the effectiveness of ultrasound-guided Pecs block with intravenous ketamine versus intravenous ketamine infusion alone in preventing Chronic Post-Surgical Pain (CPSP) in…
- Conditions
- Breast Cancer, Pain, Chronic, Post Surgical Pain
- Trial name
- NCT07197684
- Testing
- Ketamine, Pecs block, Nalbuphine
- Volunteers
- 120 people
- Sponsor
- Aga Khan University
Breast Neoplasms, Pain, Postoperative
Persistant Post-mastectomy Pain in Breast Cancer : Incidence and Risk Factors
Post Mastectomy Pain Syndrome (PMPS) is a major complication of breast surgery responsible for depression and disability. The project consists of a prospective cohort on patients going for oncological breast surgery at National…
- Conditions
- Breast Neoplasms, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04676438
- Where
- 2 sites in Morocco
- Volunteers
- 722 people
- Sponsor
- Moroccan Society of Surgery
Mastectomy, Pain, Chronic
Affecting Factors for Chronic Pain After Mastectomy
Chronic post-mastectomy pain (CPMP) is a significant issue affecting many women after mastectomy. Factors like age, treatment type, and pre-surgery pain can increase the risk of developing this condition.
- Conditions
- Mastectomy, Pain, Chronic, Pain, Acute, Breast Surgery
- Trial name
- CPMP (NCT06592053)
- Testing
- Breast Cancer Surgery Pain
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Ankara Etlik City Hospital
Breast Cancer Surgery, Post Operative Pain
The Effects of Peri-Operative Pregabalin on Post-Operative Pain Following Breast Cancer Surgery With Axillary Node Dissection: A Pilot Study
Breast cancer is a devastating disease. Some women with breast cancer undergo surgery to remove the breast and lymph nodes in the axilla (armpit).
- Trial name
- NCT00852683
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Nova Scotia Health Authority
Breast Cancer
Short and Long Term Effects of a Physical Therapy Program After Breast Cancer Surgery
Objectives: To evaluate the pressure pain threshold, shoulder biomechanics, cardiorespiratory function and the quality of life associated with the short and long-term physical therapy rehabilitation following breast cancer…
- Trial name
- NCT04116281
- Testing
- Rehabilitation after breast cancer surgery
- Where
- Chile
- Volunteers
- 36 people
- Sponsor
- Universidade Federal de Sao Carlos
Breast Cancer
Genetic, Neurophysiological and Psychological Predictive Factors of Chronic Neuropathic Pain After Surgery for Breast Cancer
The aim of the study is to establish the genetic, neurophysiological and psychological phenotype of the patients presenting a persistent neuropathic pain after surgery of the breast cancer, by comparing the neuropathic painful…
- Trial name
- DOLORISKSEIN (NCT02944721)
- Testing
- Genetical analyses, Chronic pain identification questionnaires, Neurophysiological and psychophysical evaluations
- Where
- 2 sites in France
- Sponsor
- Hopital Foch
Shoulder Pain, Late Effect
An Individualised Treatment vs. a Minimal Program in Women With Late-term Shoulder Impairments After Breast Cancer.
In breast cancer patients late-term upper limb sequelae, such as shoulder pain and impaired shoulder function remain common after primary breast cancer surgery.
- Conditions
- Shoulder Pain, Late Effect, Breast Cancer, Rehabilitation
- Trial name
- NCT05277909
- Testing
- The expert assessment of shoulder impairments and individualised treatment plan, A minimal physiotherapeutic rehabilitation program delivered in a pamphlet
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- Vejle Hospital
Breast Cancer
Physical Activity Intervention for the Improvement of Pain in Young, Hispanic Breast Cancer Survivors
This clinical trial tests whether increased activity throughout the day can improve the chronic pain and associated symptoms that breast cancer survivors may experience after surgery.
- Trial name
- NCT06260332
- Testing
- Supportive Care (Fitbit)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- New Mexico Cancer Research Alliance
Breast/Surgery, Postoperative Complication
Serratus Plane Block for the Prevention of Chronic Pain After Breast Cancer Surgery
This study compare the "Serratus block plane" (SPB) and the local infiltration of the tissue in the prevention of acute and chronic pain after breast cancer surgery.
- Conditions
- Breast/Surgery, Postoperative Complication, Chronic Pain
- Trial name
- NCT02838173
- Testing
- serratus plane bloc : Ropivacaine 2mg/ml (0,3ml/kg), tissue infiltration : Ropivacaine 2mg/ml (0,3ml/kg)
- Volunteers
- 110 people
- Sponsor
- Erasme University Hospital
Breast Surgery, Macromastia
Comparison of ESP and SPSIP Blocks in Breast Surgery
This study aims to compare the efficacy of the ESP and SPSIP blocks in managing postoperative pain following breast surgery. Breast surgery, particularly after oncological and reconstructive procedures, often leads to significant…
- Conditions
- Breast Surgery, Macromastia, Mammaplasty, Modified Radical Mastectomy
- Trial name
- NCT06611644
- Testing
- Erector Spinae Plane Block, SPSIPB blcok, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Çanakkale Onsekiz Mart University
Breast Cancer Surgery Pain, Breast Cancer
Qigong For PPSP In Breast Cancer Pain In Breast Cancer Survivors
Studies have shown that on-going pain following breast surgery is common and may limit the ability to participate in physical activity, cause tiredness, difficulty in daily chores/activities as well as other problems.
- Conditions
- Breast Cancer Surgery Pain, Breast Cancer, Stage 0-III Breast Cancer
- Trial name
- NCT02848989
- Testing
- Qigong Mind-Body Exercise
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Dana-Farber Cancer Institute
Postoperative Pain, Quality of Recovery
Quality Study of Anesthetic Technique on Breast Cancer Surgery
Previous studies have shown that paravertebral block (PVB) has the potential to reduce pain and side effects after breast surgery when used in addition to general anesthesia or sedation.The investigators would like to further…
- Conditions
- Postoperative Pain, Quality of Recovery, Satisfaction
- Trial name
- PQSAT (NCT01499836)
- Testing
- PVB
- Where
- Taiwan
- Volunteers
- 101 people
- Sponsor
- Nai Liang Li