Clinical trials: Breast Cancer Survivorship
Breast Cancer Survivorship
The Breast Cancer & Physical Activity Level (BC-PAL) Pilot Study
The Breast Cancer \& Physical Activity Level (BC-PAL) pilot study is a randomized controlled pilot trial aimed at evaluating whether total physical activity levels, health-related fitness and patient reported outcomes are…
- Trial name
- BC-PAL (NCT03564899)
- Testing
- Lighter intensity physical activity intervention, Higher intensity physical activity intervention
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- AHS Cancer Control Alberta
Invasive Breast Cancer
Evaluation of the RESTART Survival Programme
The RESTART survivorship programme has been implemented in the care pathway for patients with localised breast cancer since 2022.
- Trial name
- NCT06283511
- Testing
- educational workshops
- Volunteers
- 200 people
- Sponsor
- Jules Bordet Institute
Breast Cancer, Prostate Cancer
Survivorship Care Plans in a Community Oncology Practice
This is a two part observational study evaluating the feasibility of implementing an EHR-based model within a community oncology practice.
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer
- Trial name
- NCT03028584
- Testing
- Survey
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Breast Cancer Survivorship
Patient Priorities for Survivorship Care in Older Breast Cancer Survivors
The objective of this study is to adapt the Patient Priorities Care (PPC) framework to breast cancer survivorship via a user-centered approach, through an iterative process in which patients and their physicians help to refine…
- Trial name
- NCT06478589
- Testing
- Adapted Patient Priorities Care (PPC) approach, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- The University of Texas Health Science Center, Houston
Neoplasms, Cancer
Cancer Experience Registry (CER) for Cancer Patients and Caregivers
The Cancer Experience Registry®: An Online Survey Research Study to Understand the Experiences of Those Impacted By a Cancer Diagnosis. The Registry is a web-based platform to distribute cross-sectional and longitudinal surveys.
- Conditions
- Neoplasms, Cancer, Caregiver
- Trial name
- CER (NCT02333604)
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Cancer Support Community, Research and Training Institute, Philadelphia
Breast Cancer, Prostate Cancer
Survivorship Promotion In Reducing IGF-1 Trial
This is a prospective, single-center randomized trial with three arms, and an allocation ratio of 1:1:1. The study design is an efficacy study to evaluate the effect of metformin and coach-directed behavioral weight loss versus…
- Conditions
- Breast Cancer, Prostate Cancer, Lung Cancer, Colon Cancer
- Trial name
- SPIRIT (NCT02431676)
- Testing
- Metformin, Coach Directed Behavioral Weight Loss, Self-control weight loss
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Breast Cancer
Individualizing Approaches to Surveillance Mammography in Older Breast Cancer Survivors - The I-MAMMO Study
This study evaluates the effectiveness of a Shared Decision-Making (SDM) toolkit designed to support older breast cancer survivors aged 80 and above in making informed decisions about continuing surveillance mammography.
- Trial name
- I-MAMMO (NCT07123649)
- Testing
- Shared Decision-Making Toolkit
- Where
- United States
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer
The Effect of Digital Breast Tomosynthesis in Breast Cancer Long-term Survival: a Single Institution Study
To investigate whether digital breast tomosynthesis (DBT) benefits survival improvement.
- Trial name
- NCT05600257
- Testing
- DBT, DM
- Where
- Taiwan
- Volunteers
- 1,517 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Breast Cancer Survivorship
To Live Better After Breast Cancer Treatment
The most common cancer among women in Sweden is breast cancer. Advances in treatment have improved survival, but these advances have come at a steep price since most treatments impose substantial morbidity and burden on patients…
- Trial name
- NCT06471452
- Testing
- Interaktor
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Breast Cancer Survivorship, Muscle Oxygenation
Muscle Oxygen Saturation and Functional Capacity in Breast Cancer Survivors
This cross-sectional observational study aims to assess muscle oxygen saturation (SmO2) in the intercostal, quadriceps, and triceps surae muscles using near-infrared spectroscopy (NIRS) during functional exercise tests in breast…
- Conditions
- Breast Cancer Survivorship, Muscle Oxygenation, Near-infrared Spectroscopy, Exercise
- Trial name
- NCT06976593
- Testing
- Functional Exercise Testing and Muscle Oxygen Saturation Measurement
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Extremadura
Breast Cancer, Survivorship
Culturally Aware AET Non-Initiation Intervention
The purpose of this study is to examine the feasibility and acceptability of a brief, nurse-led intervention to support breast cancer survivors who have delayed initiation of hormonal therapy or who have concerns about starting…
- Conditions
- Breast Cancer, Survivorship, Treatment Compliance, Treatment Adherence
- Trial name
- NCT05465408
- Testing
- Culturally Aware Adjuvant Endocrine Therapy (AET) Non-Initiation Intervention
- Where
- 11 sites in United States
- Volunteers
- 35 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer Stage IV
The Benefit of Surgery in Stage IV of Breast Cancer
Treatment of Metastatic Breast Cancer is not usually considered curative. Recent retrospective studies have demonstrated that resection of the breast tumor in patients with primary metastatic breast cancer is associated with a…
- Trial name
- NCT04697043
- Testing
- Systemic therapy followed by surgery if the disease is not progressive
- Where
- Iran
- Volunteers
- 212 people
- Sponsor
- Tehran University of Medical Sciences
Triple-Negative Breast Cancer (TNBC)
Survival Outcomes of Residual Disease in Triple-Negative Breast Cancer
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer associated with a poor prognosis. Although neoadjuvant therapy improves outcomes in patients who achieve a pathological complete response, the…
- Trial name
- ReS-TNBC (NCT07714382)
- Testing
- Chemo-radiotherapy alone, Not applicable- observational study
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Breast Cancer, Colorectal Cancer
KanSurvive: Testing a Model for Improving Cancer Survivorship Care in Rural Practice
Approximately, 20 rural primary care practices to participate in a delayed intervention-controlled trial. Phase I: Formal and structured work flow evaluations to better identify specific gaps in processes of care while assessing…
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
- Trial name
- KANSURVIVE (NCT04763824)
- Testing
- KanSurvive ECHO and Practice Facilitation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Breast Cancer
Radiotherapy After Primary Chemotherapy for Breastcancer
The primary aim of the study is to evaluate the 5 yr locoregional recurrence rate (LRR) in cT1-2cN0-1(cytology/histology and/or positive SN, excluding patients with > 3 pathologic axillary nodes on imaging) breast cancer…
- Trial name
- RAPCHEM (NCT01279304)
- Testing
- radiation - no radiation see intervention description, radiation: see intervention description
- Where
- 6 sites in Netherlands
- Volunteers
- 851 people
- Sponsor
- Maastricht Radiation Oncology
Breast Cancer
Relationship of pAKT to Survival in Patients With Node-Positive Breast Cancer
This study will examine the relationship of a protein called pAKT to survival of breast cancer patients with one or more positive axillary lymph nodes.
- Trial name
- NCT00965276
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- National Cancer Institute (NCI)
Metastatic Breast Cancer Starting a Third Line Chemotherapy
Prospective Construction and Validation of a Prognostic Score to Identify Among Patients With Metastatic Breast Cancer Those Who Benefit From a Third Line Chemotherapy in Terms of Overall Survival
This is a biomedical study of interventional type. The trial will include 270 patients (180 patients in the first cohort and 90 patients in a second cohort) over a period of 3 years + 2 years of follow up.
- Trial name
- METAL3 (NCT01574170)
- Testing
- Construction of a prognostic score (non-drug intervention types)
- Where
- 16 sites in France
- Volunteers
- 267 people
- Sponsor
- Institut Claudius Regaud
Breast Cancer
Technology and Navigation to Improve Survivorship Care
The goal of this research study to learn about breast cancer survivorship and possible ways to improve breast cancer survivorship programs using technology.
- Trial name
- NCT01663870
- Testing
- Audio Recorded Interviews, Focus Group Session, Website Session
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Survival
PG2 Breast Cancer Evaluation in Adjuvant Medicine-Survival Study
Astragalus polysaccharides (APS), acting as an immunomodulator, is known to modulate the tumor microenvironment and inhibit tumor growth and progression, thereby suggesting potential as an adjuvant cancer therapy to improve…
- Trial name
- PG2 BEAM-S (NCT07601113)
- Testing
- Astragalus polysaccharides 500 mg
- Where
- 5 sites in Taiwan
- Volunteers
- 66 people
- Sponsor
- Kun-Ming Rau
Breast Cancer, Triple Negative Breast Neoplasms
NordicTrip, a Translational Study of Preoperative Chemotherapy in TNBC
Primary aim: To compare the effect on pathologic complete response (pCR) rate of adding capecitabine to carboplatin based preoperative chemotherapy in early ER-negative and HER2-negative breast cancer.
- Trial name
- NCT04335669
- Testing
- epirubicin, cyclophosphamide, paclitaxel, carboplatin, pembrolizumab, epirubicin, cyclophosphamide, capecitabine, paclitaxel, carboplatin, pembrolizumab
- Where
- 24 sites in Denmark, Sweden
- Volunteers
- 325 people
- Sponsor
- Lund University Hospital