Clinical trials: Breast Cancer-Related Lymphedema
Breast Carcinoma
A Correlational Study: Breast Cancer-related Chest Wall Lymphedema, Quality of Life, and Shoulder Function
This study evaluates how swelling in the chest following breast cancer treatment may affect patients' quality of life and shoulder function.
- Trial name
- NCT06285747
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Mayo Clinic
Breast Cancer Related Lymphedema
Gait Characteristics of Women With Breast Cancer-Related Lymphedema
Upper extremity lymphedema is one of the most common problems associated with cancer treatments in breast cancer survivors. Lymphedema causes asymmetry, changes posture, decreases arm swing due to increased weight, and as a…
- Trial name
- NCT07011277
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Breast Cancer
Exploring the Efficacy and Feasibility of the LymphaTech Scanner for Breast Cancer-Related Lymphedema Screening
This research will compare the absolute volumes of the upper extremity using both the LymphaTech Scanner and Perometer in a cohort of patients with a history of invasive or in-situ carcinoma of the breast.
- Trial name
- NCT03861975
- Testing
- Breast Cancer-Related Lymphedema Measurements
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Breast Neoplasms
Preventive Intervention Against Lymphedema After Breast Cancer Surgery
This study will examine whether lymphedema after breast cancer surgery can be reduced. In a randomised controlled design the aim is to investigate whether an early intervention with progressive resistance training and close…
- Trial name
- LYCA (NCT02518477)
- Testing
- exercise
- Where
- Denmark
- Volunteers
- 158 people
- Sponsor
- Danish Cancer Society
Breast Cancer Female, Breast Cancer Lymphedema
The Effect of Arm Exercises on Arm Oedema After Breast Cancer Surgery
In order to prevent lymphedema after breast surgery, patients are advised to know the risk factors for lymphedema and to avoid situations that may cause lymphedema, to perform active and passive arm exercises, to evaluate the…
- Trial name
- NCT05303675
- Testing
- exercise and training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gulseren MARAS
Breast Cancer, Lymphedema
Efficacy and Safety of Wuling San on Breast Cancer-related Lymphedema
The purpose of this study is to assess the efficacy and safety of Wuling San, a traditional Chinese medicine, in reducing arm volume excess in women with stage I-II breast cancer related unilateral lymphedema.
- Trial name
- NCT02726477
- Testing
- Wuling San
- Where
- 3 sites in China
- Volunteers
- 200 people
- Sponsor
- Fourth Affiliated Hospital of Guangxi Medical University
Breast Cancer, Lymphedema
Lymphedema Prevention in Breast Cancer
OBJECTIVE: To find out the effectiveness of early application of Manual Lymph Drainage in the prevention of upper limb lymphedema after breast surgery and axillary lymphadenectomy in women with breast cancer.
- Trial name
- NCT04112966
- Testing
- 14 sessions of manual lymphatic drainage technique, the health education
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Castilla-La Mancha
Lymphedema Arm, Lymphedema; Surgical
Assessment of Muscle Strength and Volume Changes in Patients With Breast Cancer- Related Lymphedema
This study aims to find whether complete decongestive therapy used in breast cancer-related lymphedema has an effect on muscle strength in the affected arm, while assessing the efficacy of the therapy itself.
- Trial name
- NCT03945838
- Testing
- Complete Decongestion Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Ege University
Breast Cancer
Prospective Surveillance for Breast Cancer-Related Lymphedema
This randomized trial will test the effect of a prospective surveillance program for early detection and subclinical management of breast cancer-related lymphedema on the prevalence of chronic lymphedema.
- Trial name
- PROTECT (NCT04522648)
- Testing
- Prospective surveillance
- Where
- 3 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lymphedema, Breast Cancer
To Assess the Efficacy of the LYMPHA in the Prevention of Lymphedema Following Axillary Dissection for Breast Cancer
Lymphedema is the Build-up of Lymph Fluid in the Body's Tissue Causing Chronic, Debilitating Swelling. This Commonly Occurs as a Result of a Disruption of the Lymphatic System During Lymph Node Dissection Surgeries.
- Trial name
- LYMPHA (NCT04328610)
- Testing
- LYMPHA(LYmphatic Microsurgical Preventive Healing Approach) technique
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Pusan National University Hospital
Breast Cancer, Pain
Enhancing Management of Chronic Pain and Symptoms Among Women Treated for Breast Cancer (Lymph-Flow)
The purpose of this research study is to conduct a randomized clinical trial to evaluate the efficacy of the web-based The-Optimal-Lymph-Flow ™ system for managing chronic pain and symptoms related to lymphedema focusing on…
- Conditions
- Breast Cancer, Pain, Lymphedema
- Trial name
- Lymph-Flow (NCT02462226)
- Testing
- The-Optimal-Lymph-Flow, Arm Precaution
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- NYU Langone Health
Breast Cancer
A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer
Breast cancer is estimated to affect approximately 300,000 women in the US in 2023. Studies demonstrate that 1 in 5 will develop breast cancer related lymphedema secondary to the treatments that they receive.
- Trial name
- NCT06327490
- Testing
- ICG-guided manual lymphatic drainage, Traditional manual lymphatic drainage, Indocyanine green
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Lymphedema, Secondary Lymphedema
Efficacy of Complete Decongestive Therapy for Limb Lymphedema: Response Profile and Predictive Modeling
Background: Complete decongestive therapy (CDT) is the standard treatment for lymphedema, but response varies by localization and laterality.
- Conditions
- Lymphedema, Secondary Lymphedema, Breast Cancer-Related Lymphedema, Upper Extremity Lymphedema
- Trial name
- LYMPH-PROG (NCT07878598)
- Testing
- Intensive phase of Complete Decongestive Therapy
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- Ryazan State Medical University
Breast Cancer Related Lymphedema
Manual Lymphatic Drainage With Diaphragmatic Breathing Exercises in Post Radical Mastectomy
Lymphedema is a persistent and chronic swelling condition that commonly develops after breast cancer surgeries involving axillary lymph node dissection (ALND).
- Trial name
- NCT07676045
- Testing
- Manual Lymphatic Drainage, Diaphragmatic Breathing Exercises
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- University of Lahore
Breast Cancer, Upper Extremity Lymphedema
Immunotherapy for the Treatment of Breast Cancer Related Upper Extremity Lymphedema (BCRL)
The purpose of this study is to assess the efficacy of QBX258, a compound developed by Novartis Corporation composed of two antibodies, in reducing arm volume excess in women with stage I-II breast cancer related lymphedema.
- Trial name
- NCT02494206
- Testing
- QBX258
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer Related Lymphedema, Lymphedema of Upper Arm
Clinical Evaluation of a Novel Wearable Compression Technology in the Treatment of Lymphedema, An Open-Label Controlled Study
An open-label study to clinically assess a novel wearable advanced compression technology (Dayspring™) undertaken to determine if potential barriers to lymphedema self-care were effectively addressed.
- Conditions
- Breast Cancer Related Lymphedema, Lymphedema of Upper Arm, Lymphedema, Quality of Life
- Trial name
- DAYSPRING (NCT04659564)
- Testing
- User of Dayspring device
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Koya Medical, Inc.
Lymphedema
Efficacy of Multi-waved Locked System Laser Versus Cold Compression Therapy on Breast Cancer-related Lymphoedema
This study was conducted: To investigate the effect of MLS Laser in the management of patients with unilateral BCRL regarding lymphatic flow, volumetric measurement and HRQL assessment.
- Trial name
- NCT05911854
- Testing
- Multi-waved Locked System Laser, Cold Compression therapy, complete decongestive therapy
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Postmastectomy Lymphedema
Virtual Reality Versus Proprioceptive Neuromuscular Facilitation on Postmastectomy Lymphedema
This study aimed to compare the therapeutic efficacy of VR and PNF on lymphedema and function in unilateral post-mastectomy lymphedema (UPML) patients. The patients were subdivided into two equal groups, 15 in each.
- Trial name
- NCT04185181
- Testing
- virtual reality, proprioceptive neuromuscular facilitation, complete decogestive therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- doaa atef
Breast Cancer Related Lymphoedema, Lymphoedema
LYT-100 in Patients With BCRL
This is a trial of up to 6-months duration for safety, tolerability, clinical efficacy assessments, PK and biomarkers analysis in breast carcinoma patients with secondary lymphoedema
- Trial name
- NCT04243837
- Testing
- LYT-100 BCRL
- Where
- 8 sites in United States, Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- PureTech
Breast Cancer, Breast Cancer Related Lymphedema
Photobiomodulation Therapy for the Management of Breast Cancer-related Lymphedema
Up to one out of five patients with breast cancer will develop lymphedema in the upper extremity after cancer treatment. Patients with breast cancer-related lymphedema (BCRL) suffer from pain, heaviness, tightness, and a…
- Conditions
- Breast Cancer, Breast Cancer Related Lymphedema, Lymphedema of Upper Arm
- Trial name
- LymphLight (NCT04690439)
- Testing
- Photobiomodulation therapy (PBMT), Manual Lymphatic drainage
- Where
- 2 sites in Belgium
- Volunteers
- 104 people
- Sponsor
- Jessa Hospital