Clinical trials: Breast Health
Breast Cancer Screening, Colorectal Cancer Screening
Improving Cancer Screening and Follow-up in Community Health Centers
This is an implementation science study that examines implementation of a single intervention and the development of practice-level implementation strategies to facilitate implementation of the intervention.
- Conditions
- Breast Cancer Screening, Colorectal Cancer Screening, Implementation
- Trial name
- NCT05756725
- Testing
- Practice-Level Implementation Strategies
- Where
- 3 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Breast Health
Image Quality Assessment for Screening and Diagnostic Mammography
This study is being conducted to determine the image quality of images using a new investigational medical imaging device.
- Trial name
- NCT02786004
- Testing
- Full Field Digital Mammography, Digital Breast Tomosynthesis
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- GE Healthcare
Breastcancer
A Comparative Study Between Oncoplastic Breast Surgery and Standard Conservative Surgery:Margin Status and Patient Satisfaction
This non randomized study is a comparative study between standard conservative breast surgery and oncoplastic surgery as regard margin status and patient satisfaction.
- Trial name
- NCT03012152
- Testing
- Standard conservative breast surgery, Oncoplastic breast surgery
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Pre-exposure Prophylaxis, HIV Prevention
UNCPM 22314 - Pregnancy, Infant and Maternal Health Outcomes Study
The primary purpose of this study is to assess the safety of long-acting injectable cabotegravir (CAB-LA) and oral pre-expose prophylaxis (PrEP) (FTC/TDF or 3TC/TDF) for the prevention of HIV during pregnancy and breastfeeding…
- Conditions
- Pre-exposure Prophylaxis, HIV Prevention, Pregnancy Related
- Trial name
- PrIMO (NCT06158126)
- Testing
- Initiating daily oral PrEP during pregnancy, Already using daily oral PrEP at the time of pregnancy diagnosis, Initiating injectable PrEP during pregnancy
- Where
- Malawi
- Volunteers
- 621 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Breast Neoplasm, Osteoporosis, Postmenopausal
Strength Training for Older Breast Cancer Survivors
Women aged 50 and older are disproportionately affected by breast cancer, not only in terms of new diagnoses, but also in terms of survivorship.
- Trial name
- NCT00591747
- Testing
- Resistance Exercise, Flexibility Training
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- OHSU Knight Cancer Institute
Thoracic Neoplasm, Pelvic Neoplasm
Oncologic Therapy Support Via Means of a Dedicated Mobile App
The present single-center prospective exploratory study, conducted at Heidelberg University Hospital, assesses the feasibility of introducing a concept for additional patient care based on a mobile application for patients…
- Conditions
- Thoracic Neoplasm, Pelvic Neoplasm, Radiotherapy; Complications, Oncologic Disorders
- Trial name
- OPTIMISE-1 (NCT03168048)
- Testing
- mobile application
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Breastfeeding
Evaluation of a Wearable Technology to Support Breastfeeding Women
This study aims to evaluate a wearable technology developed to support breastfeeding women. The study will assess the performance of sensors in the wearable prototype for monitoring breast milk fullness and milk flow and compare…
- Trial name
- Lactogame (NCT07800078)
- Testing
- Breast Milk-Sensitive Wearable Technology
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Özlem Ülkü BULUT
Breast Neoplasms
ForeCYTE Breast Aspirator for Sample Collection and Cytological Testing of Nipple Aspirate Fluid
The purpose of this study is to measure the performance characteristics for the collection, fixation and transportation of clinical nipple aspirate fluid (NAF) specimens of the ForeCYTE Breast Aspirator across 3 independent labs…
- Trial name
- NCT02218385
- Testing
- ForeCYTE Breast Aspirator
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Atossa Therapeutics, Inc.
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
Web-based Lifestyle Program, mHealth and EMA Intervention, to Improve Weight Loss in Rural Stage I-III Postmenopausal Breast and Endometrial Cancer Survivors, HERO-C Trial
This clinical trial identifies the needs and preferences of rural stage I-III postmenopausal breast and endometrial cancer survivors and evaluates the impact of an adaptive, online program, mobile (m)Health + ecological momentary…
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Endometrial Carcinoma
- Trial name
- NCT07723235
- Testing
- Aerobic Exercise, Biospecimen Collection, Dietary Intervention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Advanced Breast Cancer
Emulation of the MONARCH-3 Trial Using Specialty Oncology Electronic Health Records Databases
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials.
- Trial name
- NCT07225790
- Testing
- Initiation of abemaciclib plus letrozole/anastrozole, Initiation of letrozole/anastrozole
- Where
- United States
- Volunteers
- 3,883 people
- Sponsor
- Brigham and Women's Hospital
Breast Cancer
Health-Related Quality of Life Coupled With Therapeutic Information on Compliance to Endocrine Therapy in Breast Cancer
Only 59% of women with breast cancer (BC) treated with Endocrine Therapy (ET) remain compliant one year upon initial prescription, despite its proven effectiveness in reducing recurrence and improving survival.
- Trial name
- COMPLIANCE (NCT04176809)
- Testing
- Routine Assessment of HRQoL coupled with Therapeutic Information
- Where
- France
- Volunteers
- 342 people
- Sponsor
- Centre Georges Francois Leclerc
Distress, Breast Neoplasms
LOL: It's All Improv After Cancer! The Impact of Improvisational Comedy on Well-Being Among Patients With Cancer
Managing distress and improving well-being is critically important for optimal survivorship care. Treatment of distress leads to better adherence to treatment, better communication, fewer calls and visits to the oncologist's…
- Conditions
- Distress, Breast Neoplasms, Quality of Life
- Trial name
- NCT02892006
- Testing
- Improvisational Comedy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Non Small Cell Lung Carcinoma, Metastatic Breast Cancer
Non-Interventional Study With Vinorelbine ORAL in Advanced Non-Small Cell Lung Carcinoma(NSCLC) and Metastatic Breast Cancer (MBC)
The purpose of this non-interventional study is to collect data on efficacy and toxicity of the use of Navelbine ORAL in daily routine in Germany (especially after availability of an 80mg capsule).
- Trial name
- NCT00890903
- Where
- Germany
- Volunteers
- 62 people
- Sponsor
- Pierre Fabre Pharma GmbH
Breast Cancer
Preserving Function in Breast Cancer Patients
Breast cancer patients experience functional limitations related to the cancer and treatment side effects. Early functional limitations affect short- and long-term quality of life, and may lead to long-term complications.
- Trial name
- NCT00429286
- Testing
- Problem Solving Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Breast Cancer
Psychological Well-being in Patients With Breast Cancer
Psychoncological evaluation in patients diagnosed with breast cancer is often limited to psychological distress and does not include evaluation of individual resources.
- Trial name
- RAISE (NCT06590727)
- Testing
- Distress Thermometer
- Where
- Italy
- Volunteers
- 2,400 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Breast Cancer Female, Surgery--Complications
Quality of Life, Aesthetic Result and Health Economy in Breast Reconstruction
A randomized clinical trial with two arms: irradiated women and non-irradiated women. Irradiated women are randomized to reconstruction with a latissimus Dorsi flap and an implant or a deep inferior epigastria perforator flap.
- Trial name
- GoBreast (NCT03963427)
- Testing
- Breast reconstruction
- Volunteers
- 220 people
- Sponsor
- Vastra Gotaland Region
Breast Feeding
Randomized Controlled Trial of Dietary Advice in Primary Care to Promote Healthy Feeding of Infants
A cluster randomized field trial to evaluate the impact that training healthcare workers in healthy feeding practices has on the nutrition and health of children.
- Trial name
- NCT00635518
- Testing
- Ten Steps for Healthy Feeding children programme
- Sponsor
- Federal University of Health Science of Porto Alegre
Breast Cancer
Promoting Early Detection of Breast Cancer in Rural Rwanda: Impact of Community Health Worker and Nurse Training
This project proposes a pilot intervention in Burera District to train rural Rwandan community health workers (CHWs) in breast awareness, and to train primary care nurses at rural health centers in the assessment and management…
- Trial name
- BCED (NCT03919682)
- Testing
- Experimental: Training, Phase 1, Experimental: Training, Phase 2
- Volunteers
- 1,203 people
- Sponsor
- Brigham and Women's Hospital
Breast Cancer
Study to Understand Relationship Between Gut Health and Toxicities of Hormonal Breast Cancer Treatment
This study will be conducted in 2 sequential parts. The first part will be a prospective, observational study. This will be followed by a small interventional, pilot study involving use of fiber supplement (chia seeds).
- Trial name
- GEMMA (NCT07553234)
- Testing
- Stool Sampling, Chia Seeds
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Colorectal Cancer, Breast Cancer
Evaluating Coaches of Older Adults for Cancer Care and Health Behaviors
The overall goal of the COACH study is to conduct a comparative effectiveness trial to assess the effectiveness of trained, participant-designated health coaches versus traditional health education efforts on cancer screening…
- Conditions
- Colorectal Cancer, Breast Cancer, Cervical Cancer
- Trial name
- COACH (NCT01613430)
- Testing
- Coach Training (COACH), Printed Educational Materials (PEM)
- Where
- United States
- Volunteers
- 1,106 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health