Clinical trials: Breast Lesions
Breast Cancer
PORTAL: Patient-reported Outcomes After Routine Treatment of Atypical Lesions
This research study is evaluating how patients feel physically and emotionally after a prior breast biopsy for specific breast conditions (including atypical lesions such as atypical ductal hyperplasia (ADH), atypical lobular…
- Trial name
- NCT03070236
- Testing
- Survey
- Where
- 6 sites in United States
- Volunteers
- 912 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Diseases
Comparison of Real-time and Shear Wave Elastography
Tissue elasticity is being increasingly used as diagnostic parameter, since at the macroscopic level benign breast lesions tend to be stiffer than normal breast tissue but softer than breast cancers.
- Trial name
- Elasto (NCT03487471)
- Testing
- Real-time elastography, Shear wave elastography
- Where
- Switzerland
- Volunteers
- 98 people
- Sponsor
- University Hospital, Basel, Switzerland
Breast Cancer
Study Into the Use of Electrical Impedance Mammography in the Diagnosis and Characterisation of Breast Disease
The Signascan Electrical Impedance Mammography (EIM) Study is a pilot study of a non-invasive medical device - a novel approach to breast cancer detection using Electrical Impedance Mammography (passing minute electrical currents…
- Trial name
- Signascan (NCT01217489)
- Testing
- Breast scan - Electrical Impedance Mammography
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Oxford University Hospitals NHS Trust
Breast Cancer
Is Any Additional Information Gained Regarding Margins Using 3D Tomosynthesis Vs 2D Conventional Digital Imaging When Imaging Operative Breast Specimens?
Patients who are diagnosed with breast cancer will have surgery to remove the tumour. Where this is a local excision not mastectomy, the tissue removed is sent for x-ray imaging to assess that the abnormality has been removed and…
- Trial name
- NCT02096185
- Testing
- 3 dimensional tomosynthesis imaging, 2 dimensional digital imaging
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Sandwell & West Birmingham Hospitals NHS Trust
Breast Cancer
Cryosurgery in Treating Women With Breast Lesions
RATIONALE: Cryosurgery kills cancer cells by freezing them. Cryosurgery followed by lumpectomy or mastectomy may be an effective treatment for breast lesions.
- Trial name
- NCT00020852
- Testing
- conventional surgery, cryosurgery
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Breast Lesions
Investigation of High Resolution Nuclear Breast Imaging Camera (MBI) in Patients Administered Tc-99m Sestamibi (ROSE)
This research protocol is designed to evaluate a novel imaging camera, only one of three of it's kind in existence, in the diagnosis of breast cancer.
- Trial name
- ROSE (NCT01368939)
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Skin Lesion
Neopep-S-based EasyDew MD Regen Cream for Radiotherapy Subject After Breast Tumor Resection
This clinical study is conducted prospectively for 3 months after medical device treatment. It is a comparative clinical study of the leading control group.
- Trial name
- NCT06025058
- Testing
- Easy Dew MD Regen Cream
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Eun-ji Kim
Pain Management After Breast Biopsy
Comparison of Long vs. Short Acting Anesthesia for Improving Pain Management After Breast Biopsy
This study will evaluate the potential role of a long acting anesthetic (ropivacaine) in providing an extended period of pain relief for patients undergoing ultrasound guided core biopsy of the breast.
- Trial name
- NCT02085239
- Testing
- Lidocaine Ropivacaine, Lidocaine alone
- Where
- United States
- Sponsor
- TriHealth Inc.
Metastatic Cancer, Soft Tissue Sarcoma
A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumors
This is a Phase I/IIa, multicenter, open-label, consecutive cohorts, dose-escalation study of BT-001 with repeated IT administrations alone and in combination with IV infusions of pembrolizumab.
- Conditions
- Metastatic Cancer, Soft Tissue Sarcoma, Merkel Cell Carcinoma, Melanoma
- Trial name
- NCT04725331
- Testing
- BT-001, Pembrolizumab [KEYTRUDA®]
- Where
- 5 sites in Belgium, France
- Volunteers
- 31 people
- Sponsor
- Transgene
Breast Cancer
Using Diagnostic Tools to Stage Breast Cancer
This project is aimed at investigating the relative diagnostic and synergy of four state of the art breast imaging techniques (magnetic resonance imaging (MRI), full-field digital mammography (DMAM), ultrasound, and positron…
- Trial name
- NCT00367666
- Testing
- MRI, Digital Mammography, Ultrasound and Positron Emission Tomography (PET)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Pennsylvania
Breast Cancer
London Investigation Into diElectric Scanning of Lesions
The MARIA breast imaging system is a novel CE-marked radio-frequency (RF) medical imaging device. The system employs an electromagnetic imaging technique that exploits the dielectric contrast between normal and cancerous tissues.
- Trial name
- LIESL (NCT03302819)
- Testing
- MARIA scan
- Volunteers
- 994 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Breast Cancer
Pre-biopsy With Dynamic Acquisitions
This study is being done to test the ability of an investigational mammography camera to find small tumors in patients' breasts.
- Trial name
- NCT00943644
- Testing
- Molecular Breast Imaging (MBI), CZT semiconductor detectors
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- Mayo Clinic
AI (Artificial Intelligence), Mammary Cancer
Experiment on the Use of Innovative Computer Vision Technologies for Analysis of Medical Images in the Moscow Healthcare System
It is planned to integrate various services based on computer vision technologies for analysis of the certain type of x-ray study into Moscow Unified Radiological Information Service (hereinafter referred to as URIS).
- Conditions
- AI (Artificial Intelligence), Mammary Cancer, Lung Cancer, X-Rays; Lesion
- Trial name
- NCT04489992
- Where
- Russia
- Volunteers
- 133,000 people, healthy volunteers welcome
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Breast Lesions
Angiogenesis in Early Breast Cancer for Prognosis Prediction
This study will investigate the association of angiogenesis in breast cancer measured by magnetic resonance imaging and biomarkers with long-term prognosis of patients.
- Trial name
- NCT00599105
- Testing
- magnetic resonance imaging
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Neuropathic Pain, Postmastectomy Pain
Symptom Management After Breast Cancer Surgery
This trial is part of a larger, longitudinal study of symptoms that occur in the breast surgical scar area and/or ipsilateral arm following breast cancer surgery.
- Trial name
- NCT00686127
- Testing
- Lidoderm patch
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of California, San Francisco
Breast Tumor
Radiofrequency Chip for Localization of Non-Palpable Breast Lesions
The purpose of the project is to compare Radiofrequency identification device (RFID) localization technique with the current clinical standard wire localization technique.
- Trial name
- NCT03684408
- Testing
- RFID Localization, Wire Localization, RFID and Wire Localization
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Missouri-Columbia
Breast Cancer
Automated Breast Ultrasound Screening
Women with dense breasts (BIRADS 3 or 4) with a BIRADS category 1 or 2 mammogram are asked to participate in a automated volume breast ultrasound scanner.
- Trial name
- ABUS (NCT02650778)
- Testing
- Breast ultrasound
- Volunteers
- 2,257 people, healthy volunteers welcome
- Sponsor
- Northeastern Ohio Radiology Research and Education Fund
Breast Diseases
Radiomics Model Based on DCE-MRI and Ultrasound Images for Breast Lesion Classification
To develop and compare multi-modality radiomics models based on DCE-MRI, B-mode ultrasound (BMUS) and strain elastography (SE) images for classifying benign and malignant breast lesions.
- Trial name
- NCT06497023
- Where
- China
- Volunteers
- 550 people
- Sponsor
- Ma Zhe
Breast Cancer
Clinical Investigation to Evaluate the Ability of MammoWave in Breast Lesions Detection
This is a multicentric, single arm, prospective, stratified by breast density clinical investigation using Mammowave that is a device, which uses microwaves instead of ionizing radiation (X-ray)for breast lesions(BL) detection.
- Trial name
- DE-17-17 (NCT04253366)
- Testing
- Clinical investigation device class IIa not marked CE
- Where
- 3 sites in Italy, Spain
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Umbria Bioengineering Technologies
Breast Cancer, Multiple Myeloma
Treatment With Zoledronic Acid in Patients With Breast Cancer, Multiple Myeloma, and Prostate Cancer With Cancer Related Bone Lesions
Patients with bone metastases or bone lesions caused by breast cancer, multiple myeloma or prostate cancer will be treated with IV Zometa in a 15 minute infusion.
- Conditions
- Breast Cancer, Multiple Myeloma, Prostate Cancer
- Trial name
- NCT00029224
- Testing
- zoledronic acid
- Where
- 7 sites in United States
- Volunteers
- 500 people
- Sponsor
- Novartis