Clinical trials: Breast Mass
Advanced or Metastatic Pancreatic Adenocarcinoma, Advanced or Metastatic Breast Cancer (BC)
Protein-Matched ADC or PDC Umbrella Trial in Advanced Pancreatic and Breast Cancer
To evaluate the clinical efficacy (objective response rate, ORR) of mass spectrometry-based absolute quantification-guided selection and matching of ADC/PDC therapy in patients with locally advanced or metastatic pancreatic…
- Trial name
- PROBE (NCT07825753)
- Testing
- Trastuzumab emtansine (T-DM1), Trastuzumab deruxtecan (T-DXd), Datopotamab deruxtecan (Dato-DXd)
- Where
- China
- Volunteers
- 225 people
- Sponsor
- Fudan University
Hormone Receptor-Positive Breast Cancer, HER2-Negative Breast Cancer
Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer
This clinical trial aims to evaluate the effectiveness of tirzepatide in achieving a 5% or more body weight reduction in patients undergoing adjuvant treatment for hormone receptor-positive, HER2-negative (HR+/Her2-) breast…
- Trial name
- FITWISE (NCT06518837)
- Testing
- Tirzepatide
- Where
- 7 sites in United States
- Volunteers
- 40 people
- Sponsor
- Rutgers, The State University of New Jersey
Breast Neoplasms
FATLAS: Comprehensive Multi-level Characterization of Systemic and Mammary Adiposity in Breast Cancer Patients.
FATLAS is a prospective, interventional, non Investigational Medicinal Product (IMP) study aiming to characterize the micro- and macroenvironment of breast cancer according to patient adiposity in different histological and…
- Trial name
- FATLAS (NCT04200768)
- Testing
- Prospective data and sample collection
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm
Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery
This trial studies the safety and how well negative pressure wound therapy works in healing the abdominal incision in obese patients undergoing free flap breast reconstruction surgery.
- Conditions
- Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm, Mammoplasty Patient, Obesity
- Trial name
- NCT04003038
- Testing
- Negative Pressure Wound Therapy, Wound Care Management
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Neoplasms, Body Composition
Longitudinal Body Composition Assessment in Breast Cancer Patients
This observational cohort study aims to track longitudinal changes in body composition, including skeletal muscle mass and fat distribution, in patients diagnosed with breast cancer.
- Conditions
- Breast Neoplasms, Body Composition, Sarcopenia, Fat Redistribution
- Trial name
- NCT07472803
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Fibrocystic Disease of Breast, Breast Cancer
A Comparison of Breast Tomosynthesis Mammography and Conventional Breast Imaging in the Characterization of Breast Masses
The purpose of this study is to compare conventional breast imaging and diagnostic work-up (2 dimensional imaging) to digital breast tomosynthesis (3 dimensional imaging) in the appearance of non-calcified breast masses.
- Trial name
- NCT00826488
- Testing
- Digital Breast Tomosynthesis
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Washington University School of Medicine
Malignant Tumor of Breast, Benign Breast Lumps
Implantation of CEST and CESL MRI Methods for Detection of Breast Tumors
MRI is a well-established method in breast imaging. It gives excellent morphological information but does not reflect the metabolic activity leading to high proportion of false positive results.
- Conditions
- Malignant Tumor of Breast, Benign Breast Lumps, High-Risk Breast Cancer
- Trial name
- NCT05305937
- Testing
- MRI scan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Breast Cancer
Vibro-Acoustography Imaging in Diagnosing Breast Masses in Women With a Breast Mass or Breast Cancer
RATIONALE: New diagnostic procedures, such as vibro-acoustography imaging, may be an effective method of diagnosing breast cancer.
- Trial name
- NCT00627614
- Testing
- breast imaging study
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Mayo Clinic
Breast Cancer, Breast Carcinoma in Situ
EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer
The purpose of this research study is to evaluate the outcomes of two standard of care group exercise regimens to increase muscle mass in women who have been treated with breast cancer.
- Conditions
- Breast Cancer, Breast Carcinoma in Situ, Breast Cancer Female
- Trial name
- NCT06115486
- Testing
- Control Arm ACSM Guidelines, Experimental Arm 6-12-25 repetitions per set
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Breast Cancer
The Effect of Body Mass Index and Total Cholesterol Levels on Histopathological Grading in Breast Cancer Patients
Breast cancer is a widespread cancer that affects high percentiles of women worldwide.The development and aggressiveness of breast cancer cells can be evaluated depending on the histopathological grading which reflects the degree…
- Trial name
- NCT06786598
- Testing
- Cholesterol
- Where
- Syria
- Volunteers
- 85 people
- Sponsor
- Latakia University
Cancer of Breast, Healthy
Aerobic Training in Treatment for Breast Cancer
Introduction. Treatment with hormone therapy reduced the likelihood of tumor recurrence and metastasis in the patient. However, it has adverse effects such as: loss of bone mineral density, increase in body weight, metabolic…
- Trial name
- ATTBC (NCT03494400)
- Testing
- Aerobic Training Presential, Aerobic Training Home-based
- Where
- Brazil
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Breast Cancer
Characterization of Breast Masses Incidentally Detected on Chest CT
Although Computed tomography (CT) is not routinely used to evaluate beast masses, It is common to discover Incidental breast lesions on chest CT.
- Trial name
- NCT02755779
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel Aviv Medical Center
Breast Cancer
Triaging of Women Detected With a Breast Lump on Clinical Breast Examination Using Portable Ultrasound Device
This study aims to stratify women diagnosed with a lump in the breast by clinical breast examination(CBE) using a hand-held ultrasound machine. They will be stratified either with benign or potentially malignant lesion.
- Trial name
- Ultra-3 CBE (NCT07407153)
- Testing
- Portable ultrasound device
- Where
- Indonesia
- Volunteers
- 600 people
- Sponsor
- International Agency for Research on Cancer
GDM
Healthy Habits During and After Gestational Diabetes
Gestational diabetes mellitus (GDM) is associated with an increased risk of childhood obesity and other adverse health outcomes.
- Trial name
- VALID III (NCT07717515)
- Testing
- Hybrid intervention, Standard Care with Passive Web Access
- Where
- Vietnam
- Volunteers
- 2,546 people
- Sponsor
- Thai Binh University of Medicine and Pharmacy
Neoplasms, Breast
Neo ALTTO (Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimisation) Study
This is a randomised, open label multicenter Phase III study comparing the efficacy of neoadjuvant lapatinib plus paclitaxel, versus trastuzumab plus paclitaxel, versus concomitant lapatinib and trastuzumab plus paclitaxel given…
- Trial name
- Neo ALTTO (NCT00553358)
- Testing
- Lapatinib, Trastuzumab, Paclitaxel
- Where
- 121 sites in Argentina, Belgium and 22 more
- Volunteers
- 455 people
- Sponsor
- Novartis Pharmaceuticals
Breast Cancer
The Efficacy of Prophylactic Antibiotic Administration During Breast Cancer Surgery in Overweight Patients.
This is a single center trial to compare the rate of surgical site infection (SSI) in normal (BMI equal to or less than 25; Control Group)) and overweight (BMI over 25) women who are undergoing breast cancer surgery.
- Trial name
- NCT00356148
- Testing
- Ampicillin/Sulbactam
- Where
- Turkey (Türkiye)
- Volunteers
- 372 people
- Sponsor
- Marmara University
Obesity and Breast Cancer
Impact of Body Mass Index on Outcomes of Breast Cancer Management
Obesity has been linked to an increased risk of developing a number of malignancies, including postmenopausal breast cancer. One of the established risk factors for breast cancer development in post-menopausal women is obesity…
- Trial name
- NCT03429504
- Volunteers
- 300 people
- Sponsor
- Assiut University
Breast Cancer, Breast Masses
Three-Dimensional Ultrasound Imaging and Spectroscopy for Characterizing Breast Masses
The purpose of the study is to test the hypothesis that quantitative ultrasound techniques including spectroscopy may be used as a non-invasive biomarker for characterization of suspected breast cancers.
- Trial name
- NCT06175078
- Testing
- Ultrasound Imaging 3D and Spectroscopy
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Sunnybrook Health Sciences Centre
Early Stage Breast Cancer, Breast Cancer Stage I
Evaluating Mass Spectrometry And Intraoperative MRI In The Advanced Multimodality Image Guided Operating Suite (Amigo) In Breast-Conserving Therapy
The purpose of this study is to investigate the use of intra-operative Magnetic Resonance Imaging (MRI) and Mass Spectrometry (MS) during breast conserving surgery, and to determine if these tests are capable of accurately…
- Conditions
- Early Stage Breast Cancer, Breast Cancer Stage I, Breast Cancer Stage II
- Trial name
- NCT02335671
- Testing
- Intra-operative Magnetic Resonance Imaging (MRI), Mass Spectrometer Analysis of Tissue Sample
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Masses
Breast Masses MRI Volumetry Compared to Post-operative Pathological Volume
Breast cancer is one of the most common malignancies afflicting women worldwide 1. Tumor size is important prognostic factor, its accurate measurement is essential for formulating surgery and chemotherapy plans.
- Trial name
- NCT07268300
- Volunteers
- 59 people
- Sponsor
- Assiut University