Clinical trials: Breast Mass
Benign Breast Nodules
Ultrasound-Guided Emulsification Therapy in the Clinical Treatment of Benign Breast Nodules
Background： Benign breast nodules are common breast diseases in women, including fibroadenomas, hyperplastic nodules, and other benign lesions.
- Trial name
- NCT07797257
- Testing
- CUSA Minimally Invasive Resection
- Volunteers
- 30 people
- Sponsor
- Chinese PLA General Hospital
Breast Cancer
Serum Estradiol (E2) Levels in Breast Cancer Patients During Endocrine Therapy by High Performance Liquid Chromatography-tandem Mass Spectrometry (LC-MS /MS)
The investigators intend to conduct a prospective cohort study to detect E2 levels during endocrine therapy in Chinese breast cancer patients using LC-MS/MS methods, and to determine the proportion of patients with premenopausal…
- Trial name
- NCT06195202
- Testing
- AIs, OFS+AIs, FUL
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Sun Yat-sen University
Breast Cancer, Taste Disorders
Taste Disorders and Their Relation to BMI, FFQ, and EORTC QLQ-BR23 in Breast Cancer Patients During Chemotherapy.
Taste disorders in cancer patients during chemotherapy could be consider as multifactorial disease, it is related with changes of food consumption.
- Conditions
- Breast Cancer, Taste Disorders, Dysgeusia, Ageusia
- Trial name
- NCT04543175
- Testing
- Taste disorder´s test
- Where
- Mexico
- Volunteers
- 106 people
- Sponsor
- Hospital General de Mexico
Colorectal Cancer, Triple Negative Breast Cancer, NSCLC - Adenocarcinoma
A Study of PDR001 in Combination With CJM112, EGF816, Ilaris® (Canakinumab) or Mekinist® (Trametinib)
The purpose of this study was to combine the PDR001 checkpoint inhibitor with each of four agents with immunomodulatory activity to identify the doses and schedule for combination therapy and to preliminarily assess the safety…
- Trial name
- NCT02900664
- Testing
- PDR001, ACZ885, CJM112
- Where
- 23 sites in United States, Belgium and 7 more
- Volunteers
- 283 people
- Sponsor
- Novartis Pharmaceuticals
Diet, Growth
The prEgnanCy and eArly Childhood nutrItion triaL (ECAIL)
The purpose of this study is to conduct a randomized controlled trial among 800 socially disadvantaged pregnant women and their families to test the effectiveness of a multi-component home visitation nutrition program, compared…
- Conditions
- Diet, Growth, Infant, Physical Activity
- Trial name
- ECAIL (NCT03003117)
- Testing
- Experimental: Intervention Program, Active comparator: Usual Care
- Where
- 2 sites in France
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- French Red Cross
Breast Lump (Malignant)
us Elastography and us Doppler in Differentiating Breast Masses
The aim of this study is to compare the diagnostic performance of grey scale US , US elastography \& color Doppler US in differentiating breast masses comparable with histopathology as a gold standard.
- Trial name
- NCT04574531
- Volunteers
- 50 people
- Sponsor
- Assiut University
Breast Neoplasm Female, Benign Breast Neoplasm
A Novel Approach in the Evaluation of Breast Masses With Doppler US
In cases with breast masses, Doppler resistive index values will be calculated for the mass and surrounding healthy tissue and the opposite healthy breast tissue, and their effect on distinguishing between benign and malignant…
- Conditions
- Breast Neoplasm Female, Benign Breast Neoplasm, Malign Breast Neoplasm, Doppler Ultrasound Diagnosis
- Trial name
- NCT07465523
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ahmet Yesildag
Bone Loss, Osteoporosis
Effect of Bisphosphonate on Bone Loss in Postmenopausal Women With Breast Cancer Initiating Aromatase Inhibitor Therapy
Elderly, postmenopausal women with breast cancer on aromatase inhibitors are at increased risk of developing bone loss and osteoporosis.
- Conditions
- Bone Loss, Osteoporosis, Breast Cancer
- Trial name
- REBBeCA II (NCT00485953)
- Testing
- risedronate
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Susan L. Greenspan
Stage III Breast Cancer, Stage IV Breast Cancer
Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs
The primary objective of this study, sponsored by Travera in Massachusetts, is to validate whether the mass response biomarker has potential to predict response of patients to specific therapies or therapeutic combinations using…
- Conditions
- Stage III Breast Cancer, Stage IV Breast Cancer, Stage III Lung Cancer, Stage IV Lung Cancer
- Trial name
- NCT04985357
- Sponsor
- Travera Inc
Diarrhoea, Malaria
Can Mass Media Campaigns Reduce Child Mortality
A cluster-randomised trial will be undertaken in Burkina Faso to investigate whether a comprehensive mass media campaign using local radio stations can change behaviours on a scale large enough to result in measurable and…
- Conditions
- Diarrhoea, Malaria, Pneumonia, Breastfeeding
- Trial name
- NCT01517230
- Testing
- Local radio campaign to reduce under-five child mortality
- Where
- Burkina Faso
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Hormone Receptor-Positive Breast Cancer
Estradiol Levels According to Body Mass Index in Premenopausal Patients With Breast Cancer
his prospective observational study will evaluate whether body mass index (BMI) is associated with serum estradiol levels in premenopausal women with hormone receptor-positive breast cancer.
- Trial name
- SIMPEC-E2 (NCT07833501)
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- D'Or Institute for Research and Education
Breast Cancer
Evaluation of the Bexa Breast Examination
Objective: The "Bexa Breast Exam," or "BBE," for the purposes of this study is defined as the use of a Bexa device in conjunction with a portable, focused ultrasound examination to identify and further evaluate abnormal breast…
- Trial name
- BBE (NCT06643767)
- Testing
- Bexa and focus ultrasound
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sure, Inc.
Palpable Breast Mass
Best Needle Size for FNA of Palpable Breast Mass:Randomised Controlled Study
Needle size from22 to 25 were used for fine needle aspiration of palpable breast lumps. In this study we choose one, randomly, and fallow the result of cytologic evaluation regarding specimen adequacy.
- Trial name
- NCT00595660
- Testing
- FNA - fine needle aspiration
- Where
- Iran
- Volunteers
- 250 people
- Sponsor
- Kashani Social Security Hospital
ER-positive, HER2-negative Breast Cancer
A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]AZD9833
The Sponsor is developing the test medicine, AZD9833 for the potential treatment of estrogen receptor (ER)-positive breast cancer.
- Trial name
- NCT05364255
- Testing
- [14C]AZD9833 Oral Solution, 75 mg
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Pancreatic Cancer, Metastatic Breast Cancer
Evaluation of the NantHealth GPS Cancer Test in Patients With Advanced Cancers
Among patients with advanced (metastatic) cancers, detailed characterizations of the tumor utilizing genomic and proteonomic techniques may help guide treatment.
- Conditions
- Pancreatic Cancer, Metastatic Breast Cancer, Metastatic Lung Cancer, Metastatic Colon Cancer
- Trial name
- NCT03073473
- Testing
- NantHealth GPS Cancer Test
- Where
- 10 sites in United States
- Volunteers
- 40 people
- Sponsor
- Cota Inc.
Breast Cancer, Nonsmall Cell Lung Cancer
A Study of [14C]GB491 in Male Healthy Subjects
This is an open-label, single-center study to evaluate the mass-balance and pharmacokinetics of GB491 in 4-8 healthy male subjects receiving a single oral 150mg dose of GB491 containing approximately 50 uCi of [14C]GB491.
- Trial name
- NCT05860582
- Testing
- [14C]GB491
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Genor Biopharma Co., Ltd.
Breast Neoplasms
Breast Lump Clipping Methods Comparison
Breast cancer is the most frequently diagnosed malignancy among women worldwide, with increasing rates in later life. It represents a significant healthcare challenge in low- and middle-income countries where limited access to…
- Trial name
- BLC (NCT07716644)
- Testing
- Breast Lesion Clip Placement
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Faisalabad
Breast Cancer
Women's Experiences of Mammography: Quantitative Evaluation
Study will develop, validate and pilot measures to assess quality of experiences of mammography. Pilot data collection and analysis will investigate modifiable factors most important in determining quality of patient experiences…
- Trial name
- WEM-Quant (NCT02829905)
- Where
- United Kingdom
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- University of Dundee
Mass Lesion
Non-Inferiority Quantitative Transmission Ultrasound Case Collection Study
Conduct a case collection study of breast imaging examinations from women with mammographically-detected breast lesions for the purpose of conducting subsequent Reader Studies.
- Trial name
- QTUS (NCT02133417)
- Testing
- Quantitative Transmission Ultrasound
- Where
- 2 sites in United States
- Volunteers
- 287 people
- Sponsor
- QT Ultrasound LLC
Lymphedema
Reduction of Lymphedema Secondary to Breast Cancer
This study evaluates the reduction of lymphedema and its complications in obese women treated with a muscle training and weight loss program as well as the improvement body composition, muscle strength, quality of life and…
- Trial name
- EJERDIETLIF (NCT04974268)
- Testing
- Specific supervised exercise and weight loss program
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud