Clinical trials: Breast Neoplasms, completed
Breast Neoplasms
The Application of Pectoral Nerve II(PECS II)block in Breast Fibroadenoma Resection Surgery
Patients were randomly assigned to the GA group, PECS II group, or TPVB group using a computer-generated random number table. Group assignments were kept in a sealed envelope, which was opened only after induction of general…
- Trial name
- PECS II (NCT06608810)
- Testing
- nerve block with 0.5% ropivacaine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Inner Mongolia Baogang Hospital
Prostate Cancer
Compare the Value of Prophylactic Versus Therapeutic Breast Radiotherapy in CASODEX
The primary objective of this trial is to examine the value of prophylactic versus therapeutic breast radiotherapy in Casodex monotherapy induced gynaecomastia and/or breast pain.
- Trial name
- COMART (NCT00590213)
- Testing
- Casodex 150mg, Radiotherapy, Haematology
- Where
- 9 sites in Turkey (Türkiye)
- Volunteers
- 125 people
- Sponsor
- AstraZeneca
Breast Cancer, Sentinel Lymph Node
Indocyanine Green Fluorescence-guided Sentinel Node Biopsy in Breast Cancer Within a North African Population: a Retrospective Study
Background Radio Isotopes and Blue dye alone or in combination are the most commonly used tracer agents in sentinel Node Biopsy for early breast cancer.
- Trial name
- NCT04879680
- Testing
- sentinel node detection
- Volunteers
- 47 people
- Sponsor
- Faculty of Medicine, Sousse
Breast Cancer, Prostate Cancer
Adherence to Oral Therapies in Advanced Breast and Prostate Cancers
AdOTAC is a pilot study, open, prospective, single-center, one-arm. The 200 patients will be included. Patient is included at Day 0.
- Trial name
- AdOTAC (NCT06435546)
- Testing
- Blood samples, Adherence to anti-cancer therapies questionnaires
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Institut de Cancérologie de Lorraine
Breast Cancer
A Study to Evaluate Lumretuzumab in Combination With Pertuzumab and Paclitaxel in Participants With Metastatic Breast Cancer Expressing Human Epidermal Growth Factor Receptor (HER) 3 and HER2 Protein
This multicenter, open-label dose-escalation study with an extension phase will evaluate the safety and pharmacokinetics of lumretuzumab in combination with pertuzumab and paclitaxel in participants with metastatic breast cancer…
- Trial name
- NCT01918254
- Testing
- Paclitaxel, Pertuzumab, Lumretuzumab
- Where
- 13 sites in Denmark, France and 2 more
- Volunteers
- 66 people
- Sponsor
- Hoffmann-La Roche
Breast Cancer
Epigenetic Testing for Breast Cancer Risk Stratification
Promoter region hypermethylation of tumor suppressor genes is one the earliest molecular events in malignant transformation and is readily detectable in apparently normal benign breast epithelium adjacent to breast cancers.
- Trial name
- NCT01501656
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Breast Cancer, Ovarian Cancer
Pilot Study Evaluating the Oncogramme: Analysis of Response to Induction Treatment of Patients With Breast or Ovarian Cancer.
The choice of treatments for cancers by systemic way - chemotherapy, hormone therapy and targeted therapies - is currently defined by criteria for population groups and not to an individual.
- Trial name
- ONCO S-O (NCT02910622)
- Testing
- Chimio-oncogramme
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Limoges
Axillary Web Syndrome
Effectiveness of Physical Therapy on Axillary Web Syndrome After Breast Cancer Surgery
Objective: To determine the effectiveness of physical therapy on the axillary web syndrome in improving pain, reducing swelling and increasing mobility of the shoulder. Design: randomized single-blinded controlled trial.
- Trial name
- PTaws (NCT02224261)
- Testing
- Physical Therapy protocol, Control
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- University of Alcala
Breast Cancer
Tamoxifen Compared With LY353381 in Treating Women With Newly Diagnosed Breast Cancer
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen or LY353381 may fight breast cancer by blocking the use of estrogen.
- Trial name
- NCT00005886
- Testing
- arzoxifene hydrochloride, tamoxifen citrate
- Where
- 9 sites in United States
- Sponsor
- University of Kansas Medical Center
Breast Cancer, Lung Cancer
Zoledronate, Vitamin D, and Calcium With or Without Strontium 89 or Samarium 153 in Preventing or Delaying Bone Problems in Patients With Bone Metastases From Prostate Cancer, Lung Cancer, or Breast Cancer
RATIONALE: Zoledronate, vitamin D and calcium may prevent or delay bone pain and other symptoms caused by bone metastases. It is not yet known whether giving zoledronate together with vitamin D and calcium is more effective with…
- Conditions
- Breast Cancer, Lung Cancer, Metastatic Cancer, Pain
- Trial name
- NCT00365105
- Testing
- Calcium, Vitamin D, zoledronic acid
- Where
- 147 sites in United States
- Volunteers
- 261 people
- Sponsor
- Radiation Therapy Oncology Group
Breast Cancer Metastatic, Hormone Receptor Positive Malignant Neoplasm of Breast
Rogaratinib, Palbociclib y Fulvestrant in Patients With Breast Cancer.
This study is an open, multicenter, prospective phase I dose escalation clinical trial followed by an expansion cohort. The aim of this study is to asses the Recommended Phase 2 Dose (R2PD) and the safety profile, among other…
- Trial name
- ROGABREAST (NCT04483505)
- Testing
- Combination, Rogaratinib + palbociclib + fulvestrant
- Where
- 8 sites in Spain
- Volunteers
- 9 people
- Sponsor
- Fundacion CRIS de Investigación para Vencer el Cáncer
Breast Cancer, Fatigue
Three Different Programs of Paced Breathing in Treating Hot Flashes in Women
RATIONALE: Paced breathing may be an effective way to reduce the number and severity of hot flashes in women who have survived breast cancer.
- Conditions
- Breast Cancer, Fatigue, Hot Flashes, Sleep Disorders
- Trial name
- NCT00569166
- Testing
- Paced breathing (15 min once daily, 6 breaths/min), Paced breathing (15 min twice daily, 6 breaths/min), Paced breathing (10 min once daily, 14 breaths/min)
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Mayo Clinic
Breast Neoplasm
Weekly Vinorelbine and Oral Capecitabine as Treatment for Stage IV Breast Cancer
The primary purpose of the study is to examine the safety and effectiveness of combination therapy consisting of daily oral capecitabine and weekly intravenous vinorelbine in stage IV breast cancer subjects.
- Trial name
- NCT00194727
- Testing
- Vinorelbine, Capecitabine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Ovarian Neoplasms, Breast Neoplasms
A Study to Determine the Management of Palmar-plantar Erythrodysesthesia (PPE) in Patients With Metastatic Ovarian or Breast Cancer Treated With Caelyx (Study P05020)
The objective of this trial is to study the management of PPE in participants with metastatic ovarian or breast cancer treated with Caelyx, and determine the frequency of use of pharmacological treatment (preventive or…
- Conditions
- Ovarian Neoplasms, Breast Neoplasms, Paresthesia
- Trial name
- NCT00746694
- Volunteers
- 154 people
- Sponsor
- Merck Sharp & Dohme LLC
Breast Cancer, Ovarian Insufficiency
Predictors of Ovarian Insufficiency in Young Breast Cancer Patients
More than two million American women are breast cancer survivors. Approximately one-third of these women are premenopausal at diagnosis and face issues related to reproduction as they undergo cancer treatment.
- Conditions
- Breast Cancer, Ovarian Insufficiency, Ovarian Failure
- Trial name
- POISE (NCT01197456)
- Where
- 2 sites in United States
- Volunteers
- 232 people
- Sponsor
- University of California, San Diego
Breast Cancer
Quadrant High Dose Rate Intraoperative Radiation Therapy (IORT) for Early-Stage Breast Cancer: A Pilot Study
This study was started to validate the possibility of administering radiation therapy during surgery to the tissue surrounding the tumor once the tumor has been removed.
- Trial name
- NCT00595062
- Testing
- Intra Operative Radiation Therapy (IORT)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer, Cognitive/Functional Effects
Doxorubicin and Cyclophosphamide in Treating Older Women With Stage I, Stage II, or Stage III Breast Cancer That Has Been Removed By Surgery
RATIONALE: Drugs used in chemotherapy, such as doxorubicin and cyclophosphamide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Breast Cancer, Cognitive/Functional Effects, Depression, Malnutrition
- Trial name
- NCT00424203
- Testing
- AC regimen, cyclophosphamide, doxorubicin hydrochloride
- Where
- 17 sites in France
- Volunteers
- 40 people
- Sponsor
- UNICANCER
Breast Cancer
Non-Invasive Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy Techniques (MRS) for Assessing Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer
The goal of this clinical research study is to learn if magnetic resonance imaging (MRI) with magnetic resonance spectroscopy (MRS) can show the effects of pre-surgical chemotherapy in breast cancer patients who are eligible to…
- Trial name
- NCT00490503
- Testing
- Magnetic Resonance Imaging (MRI), Magnetic Resonance Spectroscopy (MRS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer Female
Efficacy and Safety of Dexmedetomidine Added to Modified Pectoral's Block
The Pecs block (pectoral nerves block) is an easy and reliable superficial block inspired by the infraclavicular block approach and the intercostal abdominis plane blocks .
- Trial name
- pec's (NCT03063073)
- Testing
- Dexmedetomidine Injection [Precedex], Bupivacaine Injection [Marcaine]
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Egypt Cancer Institute
Breast Carcinoma
Virtual Support Platform (HERCaRE Application) for the Improvement of Survivorship Among Black Breast Cancer Survivors
This clinical trial studies how well a virtual support platform, the Health Equity Resources for Breast Cancer Responsive Education (HERCaRE) application (app), works in improving survivorship among Black survivors of breast…
- Trial name
- NCT07126522
- Testing
- Discussion, Internet-Based Intervention, Interview
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mayo Clinic
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