Clinical trials: Breast Neoplasms, completed
Breast Cancer, Breast Cancer Female
INTENT Pilot Study - Enhancing Adherence Intentions to Endocrine Therapy
This research is being done to pilot an intervention which aims to improve participants' experiences on Endocrine Therapy. The name of the intervention used in this research study is: Endocrine Therapy Education Program (a brief…
- Conditions
- Breast Cancer, Breast Cancer Female, Breast Carcinoma
- Trial name
- NCT06246084
- Testing
- Endocrine Therapy Education Program
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer
Primary Radiotherapy And DIEP flAp Reconstruction Trial
Many women with breast cancer now live for decades after their breast cancer treatment. In view of this, modern breast reconstruction surgery after mastectomy for breast cancer aims to reproduce as natural a breast shape as…
- Trial name
- PRADA (NCT02771938)
- Testing
- Radiotherapy before surgery
- Where
- United Kingdom
- Volunteers
- 33 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Breast Cancer
A Phase II Neo-adjuvant Study Assessing TCH (Docetaxel, Carboplatin and Trastuzumab) and TCHL (Docetaxel, Carboplatin, Trastuzumab and Lapatinib) in HER-2 Positive Breast Cancer Patients.
The primary objective: -To assess the efficacy of TCH and TCHL in neo-adjuvant treatment of HER-2 positive breast cancer, using pathological complete response (pCR) as the primary endpoint (Phase II).
- Trial name
- TCHL Phase II (NCT01485926)
- Testing
- Docetaxel, Carboplatin and Trastuzumab, Docetaxel, Carboplatin, Trastuzumab and Lapatinib
- Where
- 11 sites in Ireland
- Volunteers
- 120 people
- Sponsor
- Cancer Trials Ireland
Breast Cancer
Comparing Anastrozole-Placebo to the Combination Anastrozole-ZD1839 in Postmenopausal Patients With Estrogen Receptor and/or Progesterone Receptor Metastatic Breast Cancer
This study is being carried out to see if treatment with ZD1839 (Gefitinib) combined with Arimidex (Anastrozole) has improved efficacy over Arimidex alone in preventing progression of metastatic breast cancer.
- Trial name
- NCT00077025
- Testing
- Gefitinib, Anastrozole
- Where
- 27 sites in United States, Colombia and 2 more
- Volunteers
- 174 people
- Sponsor
- AstraZeneca
Breast Cancer
Validation of Molecular Diagnostic Assays to Detect Cancer Biomarkers in Blood & Primary Tumor in ER+/HER2- MBC
Conventional biopsy and surgical tumor resection are invasive procedures that capture only one instance of the progression of the tumor. However, the genome of tumor is not static, but it is constantly altered during treatment.
- Trial name
- NCT04480814
- Testing
- PIK3CA kit
- Where
- 4 sites in Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pharmassist Ltd
Primary Breast Cancer
Minus Anthracycline or Short-Term Versus Epirubicin and Cyclophosphamide Followed by Paclitaxel Regimen for Adjuvant Breast Cancer Therapy
We aimed to evaluate the noninferiority of short-term anthracycline-free chemotherapy (TC, six cycles of docetaxel and cyclophosphamide) or short-term anthracycline-based chemotherapy (CEF-T, three cycles of…
- Trial name
- NCT01314833
- Testing
- Docetaxel Cyclophosphamide, Cyclophosphamide Fluorouracil Epirubicin Docetaxel, Epirubicin Cyclophosphamide Paclitaxel
- Where
- China
- Volunteers
- 1,570 people
- Sponsor
- Fudan University
Breast Cancer, Chronic Myeloproliferative Disorders
Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer
RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. Combining chemotherapy and peripheral stem cell transplantation with biological therapy may kill more cancer…
- Conditions
- Breast Cancer, Chronic Myeloproliferative Disorders, Gestational Trophoblastic Tumor, Kidney Cancer
- Trial name
- NCT00003408
- Testing
- aldesleukin, recombinant interferon alfa, sargramostim
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Cancer Treatment Centers of America
Breastcancer
Breast, Omega 3 Free Fatty Acid, Ph 0
Assess the impact of dietary omega 3 free fatty acids breast cancer patients.
- Trial name
- NCT02996240
- Testing
- Omega-3 FFA
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Breast Cancer, Triple Negative Breast Neoplasms
Assessing the Efficacy of Paclitaxel and Olaparib in Comparison to Paclitaxel / Carboplatin Followed by Epirubicin/Cyclophosphamide as Neoadjuvant Chemotherapy in Patients With HER2-negative Early Breast Cancer and Homologous Recombination Deficiency
This is a multicenter, prospective, randomized, open-label phase II study evaluating the efficacy and safety of PO→EC as neoadjuvant treatment of operable and locally advanced breast cancer in patients with HR deficiency.
- Conditions
- Breast Cancer, Triple Negative Breast Neoplasms, HRpos Breast Neoplasms, BRCA 1 /2 and / or HRD
- Trial name
- GeparOla (NCT02789332)
- Testing
- PwO, PwCb, EC
- Where
- 12 sites in Germany
- Volunteers
- 107 people
- Sponsor
- GBG Forschungs GmbH
Breast Cancer
APOLLO(Aromatase Inhibitor Patient cOmpLiance Program With qoL Questionaire)
To describe patients' compliance of taking Aromatase Inhibitor as an adjuvant treatment in the postmenopausal, early breast cancer as seen under current practice
- Trial name
- APOLLO (NCT00523315)
- Where
- 19 sites in South Korea
- Volunteers
- 862 people
- Sponsor
- AstraZeneca
Breast Cancer
Studying Tissue Samples From Women Who Underwent Chemotherapy for Lymph Node-Positive Stage II or Stage IIIA Breast Cancer on Clinical Trial CLB-9741 or CLB-9344
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00897026
- Testing
- cyclophosphamide, doxorubicin hydrochloride, paclitaxel
- Where
- United States
- Volunteers
- 1,195 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Breast Cancer
Prospective Study of the Prosigna Assay on Neoadjuvant Clinical Decision-making in Women With HR+/Her2- Breast Cancer
This research study is evaluating a genomic analysis called Predictor Analysis of Microarray 50 (PAM50, by Prosigna®) as a tool to possibly guide the participant and the treating physician to choose the most personalized…
- Trial name
- NCT03749421
- Testing
- Prosigna PAM-50 assay
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer
Erlotinib and Gemcitabine in Treating Patients With Metastatic Breast Cancer Previously Treated With An Anthracycline and/or a Taxane
RATIONALE: Drugs used in chemotherapy such as gemcitabine work in different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00059852
- Testing
- erlotinib hydrochloride, gemcitabine hydrochloride
- Where
- 25 sites in United States
- Volunteers
- 61 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Breast Cancer
Standard Neoadjuvant Chemotherapy Versus Genomic Driven Chemotherapy in Patients With Breast Cancer
This randomized trial is comparing a standard neoadjuvant chemotherapy with a genomic driven chemotherapy in patients with breast cancer.
- Trial name
- REMAGUS04 (NCT01180335)
- Testing
- Chemotherapy, Genomic driven chemotherapy
- Where
- France
- Volunteers
- 303 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Physical Activity, Patient
The Relationships Between Physical Activity Level, Quality of Life and Cognitive Level in Breast Cancer Patients
The aim of this study is to determine the relationships between physical activity level, quality of life and cognitive level in patients with breast cancer and to compare the results with a population of similar age group.
- Conditions
- Physical Activity, Patient, Quality of Life, Chemotherapy
- Trial name
- NCT05275517
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Metastatic Breast Cancer
Metastatic Breast Cancer in Brazil: Characterization of Patients and Treatments
The purpose of this study is to describe demographics and socioeconomics characteristics associated to the diagnosis of metastatic breast cancer in Brazil.
- Trial name
- NCT02662868
- Where
- 24 sites in Brazil
- Volunteers
- 767 people
- Sponsor
- Latin American Cooperative Oncology Group
Breast Neoplasm Female
Peri-gravidic Exposure to Endocrine Disrupting Persistent Organic Pollutants
Breast cancer, the first female cancer, affects one in eight women in her lifetime. The increase and unequal distribution of its prevalence throughout the world, regardless of age and genetic factors (< 10% of cases)…
- Trial name
- SEINPOL (NCT03673150)
- Testing
- non intervention
- Where
- France
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Quality of Life
Symptoms Experienced and Quality of Life in Breast Cancer Receiving Radiotherapy
EORTC-QLQ-30 questionnaire filled in by participants 6 times
- Trial name
- NCT03106350
- Testing
- Questionnaire
- Volunteers
- 103 people
- Sponsor
- Chulabhorn Cancer Center
Breast Carcinoma
Development of a Genetic Counseling Patient Preference Intervention for Women at Elevated Risk for Breast Cancer
This study develops a genetic counseling patient preference intervention for women at elevated risk for breast cancer. This study aims to develop an intervention that may deliver educational videos about breast cancer, heredity…
- Trial name
- NCT05158452
- Testing
- Discussion
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Estrogen Receptor-positive Breast Cancer
A 2-Week Ketogenic Diet in Combination With Letrozole to Modulate PI3K Signaling in ER+ Breast Cancer
This is a neoadjuvant study to determine the feasibility and tolerability of 2 weeks of a very low carbohydrate ketogenic diet in combination with letrozole for patients with early stage operable ER+disease.
- Trial name
- NCT03962647
- Testing
- 2-Week Ketogenic Diet, Letrozole
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
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