Clinical trials: Breast Neoplasms, completed
Neoplasms, Breast
Pazopanib (VOTRIENT) Plus Paclitaxel (TAXOL), Pazopanib Plus Paclitaxel (TAXOL) Plus Carboplatin (PARAPLATIN), and Pazopanib Plus Paclitaxel (TAXOL) Plus Lapatinib (TYKERB)
Pazopanib will be given with TAXOL in one part, in another part pazopanib will be given with TAXOL and PARAPLATIN, and in a third part pazopanib will be given with TAXOL and lapatinib (patients separated in each part).
- Trial name
- NCT00388076
- Testing
- Pazopanib, Lapatinib, paclitaxel
- Where
- 3 sites in United States
- Volunteers
- 86 people
- Sponsor
- GlaxoSmithKline
Breast Cancer, Stage II Breast Cancer
Preoperative Hormone Therapy for Postmenopausal Women With ER+ Clinical Stage T2-4 Tumors
This phase II trial studies how well exemestane before surgery works in treating postmenopausal patients with newly diagnosed estrogen receptor positive stage II-III breast cancer.
- Conditions
- Breast Cancer, Stage II Breast Cancer, Stage III Breast Cancer
- Trial name
- NCT01831076
- Testing
- Exemestane, Exemestane and tamoxifen
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Colorado, Denver
Breast Cancer
uPAR PET/CT for Preoperative Staging of Breast Cancer Patients
The sensitivity and specificity of uPAR PET/CT for preoperative detection of lymph node metastases in breast cancer.
- Trial name
- NCT02681640
- Testing
- 68Ga-NOTA-AE105, Positron Emission Tomography PET/CT
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Breast Cancer
Detection of Aggressive Breast Tumors Using Tc-99m-NC100692
The purpose of this study is to compare two types of radioactive drugs to see if they provide the same or different information about any disease that may be present in the participants breast.
- Trial name
- NCT00888589
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Michael O'Connor
Triple Negative Breast Neoplasms
Safety and Efficacy Study of Pembrolizumab (MK-3475) in Combination With Chemotherapy as Neoadjuvant Treatment for Participants With Triple Negative Breast Cancer (TNBC) (MK-3475-173/KEYNOTE-173)
The purpose of this study is to evaluate the safety, tolerability and clinical activity of pembrolizumab (MK-3475) in combination with six chemotherapy regimens as neoadjuvant treatment for participants with triple negative…
- Trial name
- NCT02622074
- Testing
- Pembrolizumab, Nab-paclitaxel, Anthracycline (doxorubicin)
- Volunteers
- 60 people
- Sponsor
- Merck Sharp & Dohme LLC
Breast Cancer, Melanoma
Longitudinal Study of Behavioral Changes, Economic and Sociological After CAncer
Generally, French studies concerned with the quality of life of cancer patients focus on the period of treatment (up to 2 years post diagnosis).
- Trial name
- ELCCA-II (NCT02893774)
- Testing
- quality of life assessment
- Where
- France
- Volunteers
- 314 people
- Sponsor
- Institut Cancerologie de l'Ouest
Breast Cancer
Self-Reported Exercise Behavior and Short-Term Patient Outcomes in Women Undergoing Radiation Treatment for Operable Breast Cancer
Using an observational prospective design, potential subjects will be identified and screened for eligibility via medical record review of breast cancer patients scheduled for radiation therapy at Duke Radiation Oncology Clinic.
- Trial name
- NCT02050620
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Duke University
Breast Cancer, Chemotherapy Effect
Effects of Creatine Supplementation in Breast Cancer Survivors
The purpose of this study is to test the hypothesis that creatine will accelerate adaptations associated with exercise in breast cancer survivors recently completing chemotherapy.
- Conditions
- Breast Cancer, Chemotherapy Effect, Muscle Weakness, Muscle Loss
- Trial name
- NCT04207359
- Testing
- Creatine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Breast Cancer, Colorectal Cancer
Tailored Web-Based Intervention for Cancer Patients and Family Caregivers
The purpose of this pilot study is to develop a personalized, interactive, and web-based module for cancer patients and a family caregiver.
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
- Trial name
- FOCUS-WEB (NCT01415089)
- Testing
- FOCUS-Web
- Where
- 3 sites in United States
- Volunteers
- 63 people
- Sponsor
- University of Michigan
Breast Cancer
Melatonin Versus Placebo in Breast Cancer
The purpose of this research study is to determine whether melatonin taken every night can affect blood levels of estrogen or IGF (insulin-growth factor levels).
- Trial name
- NCT01805089
- Testing
- Melatonin 3 mg
- Where
- 2 sites in United States
- Volunteers
- 95 people
- Sponsor
- Dana-Farber Cancer Institute
Neuropathic Pain Induced by Mastectomy
Lidocaine IV Injection With Different Doses for Patients With Neuropathic Pain After Mastectomy
cancer has become the most common malignancy affecting women worldwide, and its incidence is increasing annually. According to the Global Cancer Observatory (GLOBOCAN) 2020 published by the International Agency for Research on…
- Trial name
- NCT07475520
- Testing
- Lidocaine 2%, Lidocaine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Breast Cancer
Vinorelbine and Docetaxel in Treating Women With Metastatic Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00006682
- Testing
- docetaxel, vinorelbine ditartrate
- Where
- 2 sites in United States
- Sponsor
- Medstar Health Research Institute
Lymphedema
The Effect of Combined Decongestive Therapy and Pneumatic Compression Pump on Body Image in Patients With Lymphedema
Patients with lymphedema may experience pain and body image issues. This study investigates the effect of Combined Decongestive Therapy and pneumatic compression pump on body image in patients with lymphedema secondary to breast…
- Trial name
- NCT02650297
- Testing
- combined decongestive therapy, pneumatic compression pump
- Volunteers
- 42 people
- Sponsor
- badri jaafari
Breast Cancer
Different Resistance Training Intensity Prescription and Monitoring Methodologies: Effects on Strength, Body Composition, and Well-being in Survivors of Breast Cancer
The goal of this clinical trial is to compare the effects of three different methods of prescribing and monitoring resistance training intensity on muscle strength, body composition, quality of life, fatigue, anxiety, and…
- Trial name
- NCT06940310
- Testing
- Daily load-velocity-based training intensity adjustment., Training intensity prescription based on an initial 1RM estimation using load-velocity relationship, Traditional training with intensity prescription based on 1RM testing.
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Universidad de Almeria
Cancer, Breast, Cancer, Gynecologic
Influence of Chemotherapy on Postural Control in Women With Cancer
The aim of this study is to understand the strategies for adapting postural control in patients who have received chemotherapy treatment for gynaecological cancer.
- Trial name
- NCT04692168
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- Aline Reinmann
Radiodermatitis, Breast Neoplasms
Patient Reported Outcomes Using Mepitel Film During Radiotherapy
Breast cancer patients in post-operative radiotherapy (RT) often experience acute skin reactions like erythema, pain, itching and oversensitivity.
- Conditions
- Radiodermatitis, Breast Neoplasms, Side Effect
- Trial name
- NCT06133218
- Testing
- Mepitel Film
- Volunteers
- 101 people
- Sponsor
- Odense University Hospital
Breast Neoplasms
A Study to Evaluate the Safety of Adjuvant Treatment With Exemestane Following Previous Treatment With Tamoxifen in Postmenopausal Women With Estrogen Sensitive Primary Breast Cancer
The purpose of this study was to give access to postmenopausal women with estrogen sensitive primary breast cancer to exemestane for the adjuvant treatment of breast cancer after the use of tamoxifen and to collect all serious…
- Trial name
- NCT00649090
- Testing
- exemestane
- Where
- 61 sites in Belgium
- Volunteers
- 1,549 people
- Sponsor
- Pfizer
Hereditary Cancer, Breast Cancer
The DIALOGUE Study: Swiss-Korean Billateral Collaboration
In Hereditary Breast and Ovarian Cancer (HBOC) communication of genetic test results with relatives is essential to cascade testing.
- Conditions
- Hereditary Cancer, Breast Cancer, Ovarian Cancer
- Trial name
- DIALOGUE (NCT04214210)
- Testing
- Adapted Family Gene Toolkit, Targeted intervention
- Where
- 8 sites in Switzerland
- Volunteers
- 128 people
- Sponsor
- University of Basel
Breast Cancer
Art Therapy Intervention for Breast Cancer Patients
As studies continue to debate the effects of quality of life on survival, increased attention is being focused on investigating complementary alternative therapies to boost overall total health in cancer patients .
- Trial name
- NCT01220960
- Testing
- art therapy
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Dr. Sarkis Meterissian
Venous Thromboembolism, Pharmacokinetics
Drug Interaction Study of Apixaban With Cyclosporine and Tacrolimus
This study aims to evaluate the pharmacokinetics (PK) of apixaban when co-administered with cyclosporine and tacrolimus in healthy volunteers.
- Conditions
- Venous Thromboembolism, Pharmacokinetics, Healthy
- Trial name
- ACT (NCT03083782)
- Testing
- Apixaban alone, Cyclosporine, Tacrolimus
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
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