Clinical trials: Breast Neoplasms Diagnosis
Breast Cancer
The Impact of Tamoxifen and Aromatase Inhibitors on Platelet Proteins
Single phlebotomy study involving women receiving tamoxifen or aromatase inhibitor therapy.
- Trial name
- NCT01341171
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Vermont
Pre-diabetes, Breast Cancer
Time Restricted Eating on Cancer Risk
Participants will be randomly assigned to either the time restricted feeding group with a daily eating period of 8 hours or the control group with a daily eating period of greater than or equal to 12 hours.
- Conditions
- Pre-diabetes, Breast Cancer, Time Restricted Feeding
- Trial name
- TREC (NCT05038137)
- Testing
- Time restricted feeding, Control
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Medical University of South Carolina
Stage IV Breast Cancer
Breast Stereotactic Radiotherapy to Primary Tumors in Metastatic Patients
This is a dose escalation study involving stage IV breast cancer patients not progressing after 6 months of first line systemic treatment.
- Trial name
- BoMB (NCT05229575)
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Campus Bio-Medico University
Metastatic Breast Cancer
Thalidomide Plus Chemotherapy Versus Chemotherapy Alone for Advanced Breast Cancer
Sixty advanced breast cancer patients are planed to enrolled in this clinical trial. Forty patients are enrolled into thalidomide plus chemotherapy group. Twenty patients are enrolled into chemotherapy alone group.
- Trial name
- NCT02649101
- Testing
- Thalidomide, Physician's choice chemotherapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhejiang Cancer Hospital
Early-Stage Breast Carcinoma
Surgical Trial to Evaluate the Impact of a Lymphoscintigraphy Prior to Sentinel Node Biopsy in Early Breast Cancer
Sentinel node biopsy is a well established tool for axillary staging in early breast cancer. So far the impact of a preoperative lymph node scintigraphy is unclear.
- Trial name
- NCT02481128
- Testing
- without preoperative access to lymphoscintigraphy findings
- Where
- 23 sites in Germany, Switzerland
- Volunteers
- 1,198 people
- Sponsor
- Kliniken Essen-Mitte
Breast Cancer
Nipple Areola Complex Conservation
96 patients were offered a nipple sparing mastectomy.
- Trial name
- NCT00641628
- Testing
- mastectomy
- Where
- Germany
- Sponsor
- Technical University of Munich
Progesterone Receptor Positive Tumor: Max 1 Line of Prior Chemotherapy, no Prior Hormone Therapy
Phase 1-2 Study of Onapristone in Patients With Progesterone Receptor Expressing Cancers
This is a multi-center, open-label, randomized, parallel group two-stage phase 1 study with a phase 2 expansion component in pts with recurrent or metastatic APRpos uterine endometrioid adenocarcinoma.
- Trial name
- NCT02052128
- Testing
- onapristone
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- Arno Therapeutics
Breast Cancer
Microwave Radiometry for the Diagnosis and Monitoring of Breast Cancer
A malignant tumor has higher temperature than normal tissue and the temperature of the tumor is dependent on the tumor growth rate. Thus tumor temperature is the universal indicator of tumor activity.
- Trial name
- RTM (NCT02514837)
- Testing
- RTM
- Sponsor
- University of Edinburgh
Breast Cancer
Factors Affecting Rehabilitation Time for Postoperative Complications Among Breast Cancer Patients
Breast cancer patients who had undergone surgery, chemotherapy and radiotherapy suffered from complications, including shoulder stiffness, lymphedema and scar contracture. These symptoms impaired one's ADL function.
- Trial name
- NCT05401877
- Testing
- therapies for breast cancer
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Taichung Veterans General Hospital
Breast Cancer-Related Lymphedema, Lymphedema
Supermicrosurgical Lymphaticovenous Anastomosis for Prevention of Upper Limb Lymphedema
Breast cancer-related lymphedema (BCRL) is one of the most common chronic complications following breast cancer treatment. This study enrolls breast cancer patients who are required to undergo axillary lymph node dissection and…
- Conditions
- Breast Cancer-Related Lymphedema, Lymphedema, Breast Cancer Invasive
- Trial name
- SLVA-PULL (NCT07026292)
- Testing
- Immediate Distal Lymphaticovenous Anastomosis (ID-LVA)
- Volunteers
- 120 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Breast Cancer, Prostate Cancer
A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer
The purpose of this study is to find out if Meaning-Centered Psychotherapy for Latinos (MCP-L) helps reduce anxiety and depression and improves quality of life compared to cognitive behavioral therapy (CBT).
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer, Thyroid Cancer
- Trial name
- NCT07225309
- Testing
- Meaning-Centered Psychotherapy for Latinos /MCP-L
- Where
- 2 sites in United States, Mexico
- Volunteers
- 300 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
A Study to Investigate the Tolerability of Subcutaneous (SC) Trastuzumab Administration in Participants With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Early Breast Cancer (eBC) Using Either a Single-Use Injection Device or Manual Administration
This multicenter study in participants with HER2-positive eBC will investigate participants' pain and discomfort of SC trastuzumab (Herceptin) administered either via a single-use injection device (SID) or via vial for manual…
- Trial name
- ESCAPE (NCT02194166)
- Testing
- Trastuzumab, Paclitaxel, Docetaxel
- Where
- 7 sites in Belarus, Kazakhstan
- Volunteers
- 90 people
- Sponsor
- Hoffmann-La Roche
Malignant Neoplasm of Breast
Neoadjuvant Pembrolizumab(Pbr)/Nab-Paclitaxel Followed by Pbr/Epirubicin/Cyclophosphamide in TNBC
Despite its aggressiveness and high incidence, to date, no targeted therapies exist for the treatment of triple negative breast cancer (TNBC).
- Trial name
- NIB (NCT03289819)
- Testing
- Pembrolizumab, nab-paclitaxel, Epirubicin
- Where
- 4 sites in Germany
- Volunteers
- 53 people
- Sponsor
- Institut fuer Frauengesundheit
Survival Outcomes
Effectiveness of Surgery for Improving Survival in Oligometastatic Breast Cancer Patients
Breast cancer is the most common malignancy in women, with stage IV disease at diagnosis in 5-10% of cases. Oligometastatic breast cancer (OMBC), defined as limited metastases (≤3-5 in ≤1-2 organs), may have better outcomes.
- Trial name
- SASI-MBC (NCT07586319)
- Testing
- surgery in accordance with current clinical guidelines, modified radical mastectomy or breast conservation surgery
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Sharif Medical Research Center
Breast Cancer
A Study of Pemetrexed and Cyclophosphamide Given Every 21 Days in Advanced Breast Cancer Patients
This is the phase 2 portion of a phase 1/2 trial, testing the use of pemetrexed and cyclophosphamide in combination for the treatment of advanced breast cancer.
- Trial name
- NCT00190671
- Testing
- pemetrexed, cyclophosphamide
- Where
- 13 sites in Austria, Czechia and 4 more
- Volunteers
- 103 people
- Sponsor
- Eli Lilly and Company
Obesity, Colorectal Cancer
Prevention of Obesity-related Cancers: Setting up of a Multi-Cancer Education and Prevention Program in Hong Kong
Obesity could increase the risk of many chronic diseases, including hypertension, cardiovascular diseases, high lipid level, diabetes, stroke, endometrial cancer and certain types of cancer which could benefit by secondary…
- Conditions
- Obesity, Colorectal Cancer, Prostate Cancer, Breast Cancer
- Trial name
- NCT04034953
- Testing
- Faecal Immunochemical Test, Prostate-Specific Antigen Test, Mammogram
- Where
- Hong Kong
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Metastatic Breast Cancer
Phase II PEMBROLIZUMAB + PALLIATIVE RADIOTHERAPY IN BC
This research study is studying radiation therapy in combination with an immunotherapy as a possible treatment for metastatic hormone receptor (HR) positive, HER2-negative breast cancer.
- Trial name
- NCT03051672
- Testing
- Pembrolizumab, Palliative radiotherapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer
Randomized Trial of Follow-up Strategies in Breast Cancer
The purpose of this study is to determine whether family physician 'routine follow-up care' of women with breast cancer in remission is an acceptable alternative to the existing system of specialist follow-up.
- Trial name
- NCT00156039
- Testing
- Follow-up Strategy for Breast Cancer
- Where
- 5 sites in Canada
- Volunteers
- 968 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Breast Cancer
The SONImage Study
SONImage is a multicenter prospective imaging side study, in which a baseline FES-PET is added to conventional work up, in 100 patients with ER+ MBC who will receive endocrine treatment ± CDK 4/6 inhibition within the SONIA study…
- Trial name
- SONImage (NCT04125277)
- Testing
- FES-PET scan, and possibly one additional visit for an FDG-PET
- Where
- 2 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- The Netherlands Cancer Institute
Depressive Symptoms, Cognitive Impairment
Non-Invasive Brain Stimulation and Cognitive Training for Depressive Symptomatology Related to Breast Cancer (ONCODEP)
The goal of this clinical trial is to test a home-delivered intervention that combines Non-Invasive Brain Stimulation techniques (transcranial direct and alternating current stimulation -tDCS and tACS-) and Online Cognitive…
- Trial name
- ONCODEP (NCT06053775)
- Testing
- Transcranial Direct Current Stimulation, Transcranial Alternating Current Stimulation, Online Cognitive Training
- Where
- 2 sites in Spain
- Volunteers
- 82 people
- Sponsor
- University of Santiago de Compostela
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