Clinical trials: Breast Reconstruction Surgery
Breast Tissue Accessory, Breast Cancer
Motiva Flora Tissue Expander PMCF
The Motiva Flora® Tissue Expander clinical study (hereafter Motiva Flora® TE study) is a 6-month, open-label, prospective, multicentre post-marketing follow-up study designed to confirm the Safety and Effectiveness/Performance of…
- Trial name
- NCT05447988
- Testing
- Breast Tissue Expander
- Where
- 5 sites in Chile, Costa Rica and 2 more
- Volunteers
- 136 people
- Sponsor
- Establishment Labs
Mammaplasty
The Use of Pecs Blocks in Combination With Exparel in Breast Reconstruction Surgery
This project intends to more thoroughly investigate the direct influence of Pecs blocks in the administration of Exparel, a non-opioid analgesic, in breast reconstruction surgery.
- Trial name
- NCT05171179
- Testing
- Breast Reconstruction (Mammaplasty), Pecs blocks, Exparel
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Surgical Wound Infection
Trial Investigating Cyanoacrylate Glue to Prevent Surgical Site Infection Following Breast Surgery
Surgical Site Infections (SSI) represents a significant complication in plastic surgery. Infections can result in a prolonged recovery and impair long-term cosmetic appearance.
- Trial name
- NCT02779296
- Testing
- 2-Octyl Cyanoacrylate Glue
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Breast Cancer
The Effect of Meditation and Massage Therapy for Breast Cancer Patients Undergoing Tissue Reconstruction
In this study we propose to explore the efficacy of massage therapy combined with meditation in women recovering from tissue reconstruction after mastectomy for breast cancer. Patients will be randomized into 2 groups.
- Trial name
- NCT01736605
- Testing
- Massage, Massage combined with meditation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Acquired Breast Deformity, Breast Cancer
Endoscopic Assisted Latissimus Dorsi Musculocutaneous Flap for Breast Reconstruction
This prospective single-arm case series evaluates the feasibility, safety, and clinical outcomes of endoscopic-assisted latissimus dorsi musculocutaneous flap harvest for breast reconstruction.
- Conditions
- Acquired Breast Deformity, Breast Cancer, Post Burn Breast Deformities
- Trial name
- NCT07691294
- Testing
- Endoscopic-Assisted Latissimus Dorsi Musculocutaneous Flap Harvest
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Kasr El Aini Hospital
Delayed Healing
PICO Breast Reduction Clinical Study Looking at Incision Healing Complications
The purpose of this study is to see if the use of a single-use negative pressure wound therapy system (NPWT) will have an effect on the reduction of post-surgical incision healing complications following breast reduction surgery…
- Trial name
- NCT01640366
- Testing
- PICO
- Where
- 6 sites in United States, France and 2 more
- Volunteers
- 200 people
- Sponsor
- Smith & Nephew, Inc.
Mammaplasty
Perioperative Care of Breast Reconstruction With Latissimus Dorsi Flap and Tissue Expander: Early Discharge Protocol in a Day Surgery Setting
The pedicled latissimus dorsi flap is a piece of tissue taken from the back that is used to reconstruct the breast after cancerous tissue is removed.
- Trial name
- NCT02791672
- Testing
- Discharge within 24 hours
- Volunteers
- 40 people
- Sponsor
- Ottawa Hospital Research Institute
Breast Cancer
Quantitative Analysis of Outcomes in Breast Reconstruction
The first objective of this study is to assess the accuracy of digital image-processing techniques to provide measurements of human breast physical dimensions.
- Trial name
- NCT00677430
- Testing
- Questionnaire, Digital Imaging
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
Targeted Nerve Surgery for the Prevention of Post-Mastectomy Pain Syndrome: A Randomized Trial
Post-Mastectomy Pain Syndrome (PMPS) is a chronic pain condition often caused by neuroma formation and nerve injury following breast cancer surgery.
- Trial name
- NCT07146009
- Testing
- Nerve Surgery, Standard of Care (Investigator Choice)
- Volunteers
- 60 people
- Sponsor
- Advanced Reconstructive Surgery Alliance
Breast Hypertrophy
Comparison of Superomedial and Inferior Pedicle Techniques in Mammaplasty
The aim of this study is to evaluate Superomedial pedicle and Inferior pedicle techniques in breast reduction for Egyptian females and compare between both pedicles regarding cosmetic outcomes, possible complications, patient…
- Trial name
- NCT03669679
- Testing
- Breast reduction
- Volunteers
- 19 people
- Sponsor
- Assiut University
Breast Cancer
Mapping Arterial Perforators Within the Breast During Mammoplasty
Breast cancer surgery can often be carried out as part of a breast reduction procedure known as 'therapeutic mammoplasty'. Where a woman has a breast with adequate volume, even larger cancers can be removed in an aesthetically…
- Trial name
- Map-total (NCT06347952)
- Testing
- Use of Acoustic and color imaging doppler during surgery for breast cancer
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Surgery, Breast Reconstruction
Impact of the Serratus Plane Block in Pain and the Use of Opioids in Breast Surgery
The purpose of this project is to evaluate the analgesic efficacy of a regional anesthesia technique ( interfascial block at the serratus muscle) performed in patient undergoing breast surgery and the effect of this technique on…
- Trial name
- NCT02905149
- Testing
- Serrato, Control
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Breast Neoplasms, Carcinoma, Ductal, Breast
Study of Autologous Fat Enhanced w/ Regenerative Cells Transplanted to Reconstruct Breast Deformities After Lumpectomy
A post-marketing study evaluating the transplantation of autologous fat augmented with Adipose Derived Regenerative Cells (ADRCs), in patients with functional and cosmetic breast deformities post segmental mastectomy or…
- Conditions
- Breast Neoplasms, Carcinoma, Ductal, Breast, Mammaplasty, Mastectomy, Segmental, Lumpectomy, Breast Reconstruction,
- Trial name
- RESTORE-2 (NCT00616135)
- Testing
- ADRC-Enhanced Autologous Fat Transplant
- Where
- 5 sites in Belgium, Italy and 2 more
- Volunteers
- 71 people
- Sponsor
- Cytori Therapeutics
Surgical Site Infection, Skin Colonization
Dressing Wear Time After Reduction Mammaplasty
This study was designed to determine whether the duration of dressing wear following reduction mammaplasty influence skin colonization and surgical site infections rates.
- Trial name
- NCT01002391
- Testing
- reduction mammaplasty
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Daniela Francescato Veiga
Breast Pain, Post-Op Complication
Serratus and Parasternal Infrapectoral Block for Breast Surgery.
Effective pain control is important following breast surgery as it improves quality of recovery, decreases the risk of chronic pain development and reduction of overall health care cost.
- Trial name
- NCT03708302
- Testing
- Unilateral serratus plane block, Unilateral parasternal infrapectoral block
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Western University, Canada
Breast Implant; Complications, Breast Implant Protrusion
Standard Silicone-based vs. B-Lite® Light Weight Breast Implant After Total Mastectomy and Radiotherapy for Breast Cancer
Reconstructive surgery with breast implants after total mastectomy for breast cancer is invariably related to several possible complications, such as atrophy of surrounding tissues, skin thinning, capsular contracture, wound…
- Conditions
- Breast Implant; Complications, Breast Implant Protrusion, Breast Cancer, Radiotherapy Side Effect
- Trial name
- BLITE-01 (NCT03737500)
- Testing
- B-Lite® light weight breast implant, Standard silicone-based breast implant
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Breast Cancer, Mastectomy; Lymphedema
Same-Day Discharge After Nipple-sparing Mastectomy or Skin-sparing Mastectomy With Breast Reconstruction
This novel study will assess the feasibility and outcomes of same-day discharge following mastectomy with implant-based pre-pectoral reconstruction.
- Conditions
- Breast Cancer, Mastectomy; Lymphedema, Same Day Surgery, Nipple-sparing Mastectomy
- Trial name
- NCT04596683
- Testing
- Same-day NSM or SSM
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Georgetown University
Breast Cancer, Right or Left Breast Mammary Reconstruction
Psycho-esthetic Impact of Tattoo Technology as Part of Mammary Reconstruction After Surgery Against Breast Cancer
Mammary reconstruction replaces total skin transplant, which may causing patient discomfort. It is a simple, painless and reproductible technology that avoids consequences and complications related to transplant.
- Conditions
- Breast Cancer, Right or Left Breast Mammary Reconstruction, Malignant Neoplasm Reconstruction by Tattoo of Areola of Female Breast
- Trial name
- NCT02464982
- Testing
- Tattoo
- Where
- France
- Volunteers
- 107 people
- Sponsor
- University Hospital, Strasbourg, France
Quality of Life, Mastectomy
Registry of Mastectomy for Breast Cancer Risk Reduction
This is a registry for patients who have a risk-reduction mastectomy ("prophylactic mastectomy") due to being at high risk for developing breast cancer, followed by breast reconstruction.
- Conditions
- Quality of Life, Mastectomy, Breast Neoplasms, Genetic Predisposition to Disease
- Trial name
- NCT00555503
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- Georgetown University
Genetic Predisposition, Breast Cancer
Pre Pectoral Implant for Immediate Breast Reconstruction Using Single Port Endoscopy in Prophylactic Indication
Implant-based reconstruction is currently the most common choice for mastectomy reconstruction. Whatever the choice of mastectomy incision, a scar remains on or near the breast volume.
- Trial name
- MRIMOP (NCT03838549)
- Testing
- Prophylactic mastectomy with immediate breast reconstruction
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier