Clinical trials: Breast Reductions
Hemopatch, Breast Cancer
The Effectiveness of Hemopatch® in the Reduction of Post-surgical Serous Drainage
Hemopatch is an alternative to reduce morbidity associated with axillary lymphadenectomy surgery, possibly contributing to improved patient management, clinical outcomes, and hospital costs.
- Conditions
- Hemopatch, Breast Cancer, Axillary Lymphadenectomy
- Trial name
- NCT04904653
- Testing
- Hemopatch, Control group
- Where
- Spain
- Volunteers
- 118 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Breast Cancer, Risk Reduction
BC Risk Assessment Before Top Surgery
The population of transgender and gender-diverse (TGD) persons in Wisconsin and the U.S. is steadily increasing. As this population grows, the number of individuals seeking gender-affirming therapies, including gender-affirming…
- Trial name
- NCT06239766
- Testing
- Breast Cancer Risk Assessment
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Breast, Posture
Physiotherapy After Breast Reduction Surgery
Background and Purpose: Breast reduction surgery is a major procedure that can lead to post-operative pain, postural deviations, and a temporary decline in quality of life.This clinical study aims to investigate the efficacy of…
- Conditions
- Breast, Posture, Mammaplasty, Sleep Quality
- Trial name
- NCT07729735
- Testing
- Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Rumeli University
Breast Cancer, Lumpectomy
Efficacy and Safety of Fibrin Sealant Vapor Heated Solvent/Detergent Treated (FS VH S/D) for Reduction of Lymphatic Leakage by Sealing Axillary Lymph Node Dissection Sites
This study will monitor the safety of FS VH S/D and will evaluate whether FS VH S/D is superior to conventional surgical procedures in the reduction of lymphatic leakage by sealing the axillary lymphatics in subjects undergoing…
- Conditions
- Breast Cancer, Lumpectomy, Mastectomy Plus Axillary Lymph Node Dissection, Lymphatic Leakage
- Trial name
- NCT00161980
- Testing
- Fibrin Sealant VH S/D, Surgical intervention alone without Fibrin Sealant VH S/D application
- Where
- 8 sites in Austria, France and 2 more
- Sponsor
- Baxter Healthcare Corporation
Pain, Postoperative, Mammaplasty
Combination Dexamethasone and Bupivacaine Pain Control in Reduction Mammaplasty
The addition of dexamethasone to non-liposomal bupivacaine in perineural blocks has been shown to enhance pain control and prolong the time until first request for postoperative narcotics in the fields of orthopedic, thoracic…
- Trial name
- NCT04919317
- Testing
- Dexamethasone 4mg, Saline
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Temple University
Breast Hypertrophy
ESPB Versus Intravenous Lidocaine for Pain After Mastopexy
Elective breast reduction surgery is associated with moderate-to-severe postoperative pain and a risk of developing chronic postsurgical pain.
- Trial name
- NCT07687069
- Testing
- Ultrasound - guided Erector Spine Plane Block (ESPB), Intraoperative intravenous lidocaine infusion
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Centre of Postgraduate Medical Education
Deleterious BRCA1 Gene Mutation, Deleterious BRCA2 Gene Mutation
Diabetes Prevention Program With or Without Hunger Training in Helping to Lower Breast Cancer Risk in Obese Participants
This pilot trial studies how well a diabetes prevention program with or without hunger training works in helping to lower breast cancer risk in obese participants.
- Conditions
- Deleterious BRCA1 Gene Mutation, Deleterious BRCA2 Gene Mutation, Ductal Breast Carcinoma In Situ, Obesity
- Trial name
- NCT03546972
- Testing
- Behavioral, Psychological or Informational Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
Penguin Cold Caps in the Prevention of Hair Loss in Breast Cancer Patients
The goal of this study is to estimate the efficacy of Penguin cold caps in preventing or reducing hair loss in patients receiving (neo)adjuvant chemotherapy (one of four common regimens) for early stage breast cancer.
- Trial name
- NCT03289364
- Testing
- Penguin Cold Caps
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Providence Health & Services
Breast Cancer, Chemotherapy
Smart VR Mindfulness for Breast Cancer: Integrating Biofeedback and Evaluating Chemotherapy Effectiveness
Breast cancer patients undergoing chemotherapy often face significant physical and emotional symptoms, with stress contributing to symptom severity.
- Conditions
- Breast Cancer, Chemotherapy, Virtual Reality, Mindfulness
- Trial name
- NCT06541587
- Testing
- mindfulness based virtual reality, mindfulness based audio practice
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Hsin Yi Lu
Risk Reduction Behavior, Breast Cancer
Nigerian Breast Cancer Risk-Reduction Study
The study will be a randomized controlled trial. The aim of the study is to determine the Breast Cancer (BC) risk and to evaluate the effect of BC risk counseling on lifestyle changes and adherence to risk-reduction practices…
- Conditions
- Risk Reduction Behavior, Breast Cancer, Health Behavior, Health Care Utilization
- Trial name
- NBCRS (NCT05834933)
- Testing
- Individualized breast cancer risk assessment, Individualized breast cancer risk counselling
- Where
- 4 sites in Nigeria
- Volunteers
- 719 people, healthy volunteers welcome
- Sponsor
- University of Ibadan
Drain Output After Breast Reduction Surgery, Breast Reductions
Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery
This study aims to evaluate whether tranexamic acid (TXA), a medication that helps reduce bleeding, can decrease fluid drainage after breast reduction surgery.
- Trial name
- NCT07131592
- Testing
- IV TXA, Topical TXA, Topical saline
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
Surgical Incision
Force Modulating Tissue Bridges for Closure of Vertical Scars in Breast Reduction
This is a prospective, within-subject randomized, single blinded study designed to follow up to forty-two (42) qualified and consenting adult females, 18-65 years of age scheduled for elective breast reduction surgery using a…
- Trial name
- NCT05028816
- Testing
- Side 1: Final layer closure with force modulating tissue bridges (FMTB), Side 1: Final layer dermal closure with poliglecaprone 25 suture, Side 2: Final layer closure with force modulating tissue bridges (FMTB)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Breast Cancer
Role of Preoperative Tapentadol in Reduction of Perioperative Analgesic Requirement After Breast Conservative Surgery in Cancer Patients.
This study evaluated the preemptive analgesic efficacy of Tapentadol in reducing peri operative analgesic requirements among patients undergoing breast cancer surgery.
- Trial name
- NCT07320781
- Testing
- Tapentadol
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Surgical Side Infections After Breast Reduction
Increased Microcirculation for Preventing Postoperative Wound Infections in Patients Undergoing Reduction Mammoplasty
In this prospective study we investigated the impact of an improved postoperative microcirculation and its effect of surgical side infections after breast reduction.
- Trial name
- NCT01538173
- Testing
- 250ml HES 6%, 9% NaCl 500ml
- Where
- Germany
- Volunteers
- 334 people
- Sponsor
- Max Dieterich
Breast Cancer
Efficacy of MBSR Treatment of Cognitive Impairment Among Breast Cancer Survivors
The purpose of this study is to evaluate MBSR(BC), an intensive meditation-based stress reduction intervention, in order to determine its efficacy in improving cognitive functioning among breast cancer survivors.
- Trial name
- NCT02786797
- Testing
- MBSR(BC) 6 Week Program, BCES 6 Week Program
- Where
- 5 sites in United States
- Volunteers
- 214 people
- Sponsor
- University of South Florida
Breast Cancer, Smoking Cessation
Brief Intervention for Tobacco and Alcohol Risk Reduction for Couple During Breast Cancer Treatment.
This study will examine the benefits of involving partner in a Screening, Brief Intervention and Referral to Treatment (SBIRT) program for tobacco and alcohol for women treated for breast cancer.
- Conditions
- Breast Cancer, Smoking Cessation, Alcohol Use, Unspecified
- Trial name
- IBMC (NCT04007549)
- Testing
- Brief motivational interview on tobacco/alcohol risk reduction
- Where
- France
- Sponsor
- Institut Bergonié
Breast Biopsy
Diagnostic US for Reduction of Benign Breast Biopsies Using US-guided Optical Tomography
Ultrasound-guided diffuse optical tomography (DOT) has demonstrated its potential role in differentiating malignant and benign breast abnormalities and in predicting and monitoring the neoadjuvant chemotherapy (NAC) response of…
- Trial name
- NCT03842358
- Testing
- Hand-held hybrid probe
- Where
- United States
- Volunteers
- 298 people
- Sponsor
- Washington University School of Medicine
HIV Infections
Feasibility and Pilot Efficacy of Flash-heated Breast Milk to Reduce Maternal-to-Child-Transmission of HIV in Tanzania
This study will investigate the feasibility of HIV positive mothers in Tanzania to correctly use the Flash-heat method to pasteurize their breast milk and for how long they are able to do so.
- Trial name
- Flash-heat (NCT00523510)
- Testing
- Infant feeding counseling that includes Flash-heat
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of California, Davis