Clinical trials: Breast Tumor Tissue
Breast Cancer, Colorectal Cancer
Satisfaction & Efficacy of Compression Using Surgical Gloves in Chemo-induced Peripheral Neuropathies
Evaluation of Satisfaction \& Efficacy of Compression Using Surgical Gloves in Peripheral Neuropathies Due to Chemotherapy
- Trial name
- ELEGANT (NCT03872908)
- Testing
- Chilled gloves, Surgical gloves
- Where
- 2 sites in France
- Volunteers
- 177 people
- Sponsor
- Centre Leon Berard
Breast Cancer
Percutaneous Cryoablation of Low-risk Early Breast Cancer
Expand the current evidence base regarding percutaneous cryoablation of early-stage, low-risk breast tumors, integrated into the standard therapeutic pathway with well-defined follow-up data, as well as data on quality of life.
- Trial name
- PRECICE (NCT06300125)
- Testing
- Cryoablation
- Where
- Italy
- Volunteers
- 234 people
- Sponsor
- European Institute of Oncology
Breast Cancer
Dose Escalation Study of HBI-8000 in Combination With Paclitaxel and Trastuzumab in Women With Advanced or Metastatic HER2+ Breast Cancer
This is a phase I multi-center dose escalation study of the histone deacetylase inhibitor (HDACi) HBI-8000 when given in combination with paclitaxel and trastuzumab in women with advanced or metastatic HER2+ breast cancer.
- Trial name
- NCT02569489
- Testing
- HBI-8000, Trastuzumab, Paclitaxel
- Sponsor
- HUYABIO International, LLC.
Ductal Carcinoma in Situ, Breast Cancer
Novel Cavity Marking Technique in Breast Cancer Patients Undergoing Breast Conservation Surgery With Oncoplastic Reconstruction for the Delivery of Adjuvant Radiotherapy and Accuracy of Recommended Re-excisions
This study will investigate a novel approach to marking surgical cavity margins following tumor resection, to allow for more accurate radiotherapy following oncoplastic surgery.
- Trial name
- NCT06903468
- Testing
- Novel cavity marking technique
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Florida
Breast Cancer, Recurrent
Partial Breast Re-irradiation in Women in Women with Locally Recurrent Breast Cancer Previously Treated with Conservative Surgery and Whole Breast Irradiation
A prospective study of partial breast re-irradiation in patients with local recurrence of breast cancer
- Trial name
- PBReI (NCT05772390)
- Testing
- Partial breast re-irradiation
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Breast Neoplasms
MM-111 in Combination With Herceptin in Patients With Advanced Her2 Amplified, Heregulin Positive Breast Cancer
This is an open-label Phase 1 trial of MM-111 in combination with Herceptin.
- Trial name
- NCT01097460
- Testing
- MM-111 + Herceptin
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- Merrimack Pharmaceuticals
Breast Cancer
ThermoBreast - Non-contact Breast Cancer Imaging Using AI-enhanced Thermography.
Breast cancer is one of the most worrisome health concerns facing women. Early detection and active patient monitoring are crucial to survival. The chances of a cure are high when detected and treated in the early stages.
- Trial name
- ThermoBreast (NCT06266026)
- Testing
- ThermoBreast - AI-based evaluation of dynamic breast thermography imaging
- Where
- Germany
- Volunteers
- 28,000 people, healthy volunteers welcome
- Sponsor
- ThermoMind Ltd.
Breast Cancer
Dose-dense (Biweekly) Carboplatin Plus Paclitaxel With or Without Trastuzumab as Neoadjuvant Treatment for Breast Cancer
The purpose of this study is to determine the efficacy and safety of dose-dense(biweekly) carboplatin and paclitaxel ± trastuzumab as neoadjuvant treatment in early breast cancer.
- Trial name
- NCT02059876
- Testing
- carboplatin and paclitaxel and or without trastuzumab
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangdong Provincial People's Hospital
Breast Cancer, Transcriptomes
Transcriptomes Breast, Ovarian and Leukocyte Hereditary Genes Predisposing to Breast and / or Ovarian Cancer
This is a case-control study of molecular diagnostics. This study requires two steps: The first part of the study will be conducted on a population of 20 women without breast cancer and, or ovarian family (Healthy Volunteers…
- Conditions
- Breast Cancer, Transcriptomes, Molecular Diagnostic, Ovarian Cancer
- Trial name
- CASOHAR (NCT02560818)
- Testing
- collection of a blood sample and breast and ovarian tissue, use of a previous blood collection for patients
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Francois Baclesse
Prostate Cancer, Breast Cancer
A Trial for a Preliminary Estimate of the Effectiveness of a Novel Theoretical Framework
Aim 1: To determine the preliminary effect sizes of al ActiveHeal EST (Engage-Sustain-Triumph) Program on occupational resilience.
- Trial name
- NCT06461416
- Testing
- ActiveHeal
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arkansas
Breast Cancer
Extension Study of Lapatinib Plus Herceptin With or Without Endocrine Therapy
Breast cancer is the most common malignancy in the U.S. Targeted therapies such as tamoxifen have been revolutionary in reducing tumor recurrences and mortality in early breast cancer.
- Trial name
- HELEX (NCT00999804)
- Testing
- Lapatinib, Letrozole, Trastuzumab
- Where
- 8 sites in United States
- Volunteers
- 128 people
- Sponsor
- Baylor Breast Care Center
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors
This longitudinal observational study examines how social health, including social support, social roles, loneliness, social anxiety, and social network characteristics, relates to physical activity, sedentary time, and quality…
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT07259304
- Testing
- Medical Device Usage and Evaluation, Quality-of-Life Assessment, Survey Administration
- Where
- 3 sites in United States
- Volunteers
- 173 people
- Sponsor
- University of Southern California
Breast Cancer
Online Stress Management and Coping Skills Training for Women With Breast Cancer
Stress Management interventions have been shown to decrease cancer-related distress, foster emotional growth and improve immune functioning during treatment for breast cancer.
- Trial name
- NCT01335152
- Testing
- Coping with Breast Cancer web-based workbook
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Talaria, Inc
Breast Cancer, Breast Cancer Recurrent
Partial Breast Re-irradiation Using Ultra Hypofractionation (PRESERVE)
Breast-conserving surgery followed by re-irradiation with partial breast irradiation (rPBI) has recently been found to be a safe alternative to mastectomy for women who have undergone prior whole breast radiation.
- Trial name
- PRESERVE (NCT05592938)
- Testing
- rPBI
- Where
- 19 sites in United States, Australia and 8 more
- Volunteers
- 171 people
- Sponsor
- University Health Network, Toronto
Breast Cancer Triple Negative
Neoadjuvant Goserelin for Triple Negative Breast Cancer
This is a phase II randomized trial that will evaluate the effect of adding LHRH analogue, goserelin, to the standard neoadjuvant chemotherapy to patients with triple negative breast cancer.
- Trial name
- NeoGONT (NCT03444025)
- Testing
- Goserelin
- Volunteers
- 180 people
- Sponsor
- Kasr El Aini Hospital
Obesity, Stage IA Breast Cancer
Pancreatic Nutritional Program for Weight Loss in Overweight/Obese Patients With Stage I-III Breast Cancer
This pilot clinical trial studies a pancreatic nutritional program for helping patients with stage I-III breast cancer who are overweight or obese lose weight.
- Conditions
- Obesity, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage IIA Breast Cancer
- Trial name
- NCT02432950
- Testing
- Dietary Intervention, Educational Intervention, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- City of Hope Medical Center
Breast Cancer
Alternative Exercise Program to Improve Skeletal Muscle Function and Fatigue in Cancer Survivors
Exercise training has beneficial effects in cancer survivors to minimize some of the side effects of cancer and its treatment and improve long-term prognosis, but there are numerous hurdles for individuals diagnosed with, and…
- Trial name
- NCT02739620
- Testing
- Neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Vermont
Randomized Controlled Trial, Breast Cancer
Acupuncture on Chemotherapy-induced Peripheral Neuropathy
Peripheral neuropathy is currently the second most common side effect after chemotherapy, second only to the side effects of blood toxicity.
- Conditions
- Randomized Controlled Trial, Breast Cancer, Chemotherapy-induced Peripheral Neuropathy, Acupuncture
- Trial name
- NCT03626220
- Testing
- acupuncture
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- China Medical University Hospital
Gonadotropin Releasing Hormone Agonists, Ovarian Function
Gonadotropin-Releasing Hormone Agonists Benefit in Preserving the Ovarian Function in Premenopausal Breast Cancer Patients During Chemotherapy
The purpose of this study is to investigate the benefits of gonadotropin-releasing hormone agonist administration during chemotherapy on preserving ovarian function and Fertility in Premenopausal breast cancer patients, as…
- Conditions
- Gonadotropin Releasing Hormone Agonists, Ovarian Function, Premenopausal, Breast Cancer
- Trial name
- NCT07127315
- Testing
- Gonadotropin-releasing hormone agonist, Chemotherapy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Helwan University
Breast Cancer, Chemotherapy Effect
Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer
Introduction: Neoadjuvant chemotherapy (NACT) has been the standard therapy for treating patients with locally advanced breast cancer (LABC). Doxorubicin-based regimen showed a clinical response for 70-80%.
- Trial name
- NCT04418089
- Testing
- Simvastatin 40mg
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
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