Clinical trials: Breast Tumour
Breast Cancer, Cervical Cancer
Muslim Americans Reaching for Health and Building Alliances (MARHABA): Patient Navigation Intervention to Increase Breast and Cervical Cancer Screening Among Muslim Women in New York City
Studies have reported Muslims in the US and NYC face numerous language and healthcare access barriers. This is a randomized randomized controlled design will be used to test the efficacy of a Patient Navigation (PN) intervention…
- Trial name
- MARHABA (NCT03081507)
- Testing
- SM-LHW, PN-LHW
- Where
- United States
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Metastatic Breast Cancer
Open-label Study of Safety, Tolerability and Pharmacokinetics of Multiple Doses of BI-CON-02 in Patients With HER2-positive Metastatic Breast Cancer, Previously Treated With Trastuzumab
This study will evaluate the safety and tolerability of BI-CON-02 in patients with HER2-positive metastatic breast cancer, previously treated with trastuzumab The clinical trial protocol for BI-CON-02 prescribes a start dose of…
- Trial name
- NCT03062007
- Testing
- BI-CON-02
- Where
- 6 sites in Russia
- Volunteers
- 6 people
- Sponsor
- Biointegrator LLC
Chronic Insomnia
Digital Cognitive Behavioral Therapy for Insomnia for Chronic Insomnia in Breast Cancer Survivors
To explore the efficacy of dCBT-I therapy for chronic insomnia among breast cancer survivors in China, we propose to conduct a randomized, parallel controlled clinical study in breast cancer survivors using a smartphone Chinese…
- Trial name
- NCT05813392
- Testing
- Digital Cognitive Behavioral Therapy for Insomnia
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Peking University First Hospital
Triple Negative Breast Cancer (TNBC)
A Nurse-Led, Coping and Supportive Intervention for Patients With Triple-Negative Breast Cancer
The purpose of this study is to explore the feasibility and acceptability of a nurse-led, coping, and supportive care intervention for patients with triple-negative breast cancer.
- Trial name
- RESTORE (NCT07513311)
- Testing
- RESTORE, Enhanced Usual Care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Massachusetts General Hospital
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Diabetes Prevention Program (METFIT) in Reducing Insulin Resistance in Stage I-III Breast Cancer Survivors
This trial studies how well a diabetes prevention program (METFIT) works in reducing insulin resistance in stage I-III breast cancer survivors.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT04560439
- Testing
- Dietary Intervention
- Sponsor
- City of Hope Medical Center
Breast Cancer, Early-stage Breast Cancer
Cardiometabolic Screening Program
This research study is being done to implement a screening program for prediabetes, diabetes, dyslipidemia and/or hyperlipidemia, and higher risk of cardiovascular disease in breast cancer survivors.
- Trial name
- NCT05386719
- Testing
- Prescreening, Screening and Enrollment, Baseline
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Breast Cancer
Radiation Therapy in Women With Low Risk Early-Stage Breast Cancer Who Have Undergone Breast Conservation Surgery
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy after surgery may kill any tumor cells that remain after surgery.
- Trial name
- IMPORT (NCT00814567)
- Testing
- radiation therapy
- Where
- United Kingdom
- Volunteers
- 2,018 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Breast Cancer
Reirradiation With Concurrent Paclitaxel for Breast Cancer
The purpose of this trial in addition to a dose finding study for concurrent Paclitaxel, will be to establish a treatment algorithm for chest wall reirradiation.
- Trial name
- NCT02058667
- Testing
- Paclitaxel+Initial Radiation+Boost
- Where
- United States
- Sponsor
- University of Kentucky
Breast Cancer (Locally Advanced or Metastatic), Tattoo Skin Markers
Tumor Margin Skin Tattooing Before Neo-adjuvant Chemotherapy in Patients With Breast Cancer
Study Description This prospective cohort study evaluates the feasibility and effectiveness of pre-neoadjuvant tumor localization using skin tattooing, with or without radiopaque clips, in patients with biopsy-proven T2-T3 breast…
- Conditions
- Breast Cancer (Locally Advanced or Metastatic), Tattoo Skin Markers, Neoadjuvant Chemoimmunotherapy
- Trial name
- TUMS (NCT07478900)
- Testing
- Skin Tattooing of Tumor Margins Prior to Neoadjuvant Chemotherapy in Breast Cancer Patients: Prospective cohort study
- Where
- India
- Volunteers
- 30 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Locally Advanced Breast Cancer, Metastatic Breast Cancer
A Study of the Safety and Effectiveness of Irosustat When Added to an AI in ER+ve Locally Advanced or Metastatic Breast Cancer.
70% of breast cancers that occur in postmenopausal women rely on the hormone oestrogen to grow and are likely to respond to hormone treatment.
- Trial name
- IRIS (NCT01785992)
- Testing
- Irosustat
- Where
- 9 sites in United Kingdom
- Volunteers
- 27 people
- Sponsor
- Imperial College London
Breast Cancer
Orall Administered Probiotics to Improve the Quality of the Vaginal Flora of Women With Breast Cancer and Chemotherapy.
The aim of this study is the improvement of the vaginal flora by at least two grades of the Nugent scale after application of oral probiotics.
- Trial name
- NCT01723592
- Testing
- Probiotics
- Where
- Austria
- Volunteers
- 27 people
- Sponsor
- Medical University of Vienna
Breast Cancer, Breast Cyst
Pilot Clinical Study on a Low-power Electromagnetic Wave Breast Imaging Device for Cancer Screening Purposes.
The trialed investigational medical imaging device is a low-power microwave breast imaging system for cancer screening purposes. It is an active device which uses non-ionizing radiation.
- Trial name
- NCT03475992
- Testing
- Low-power microwave breast imaging system
- Where
- Ireland
- Volunteers
- 25 people
- Sponsor
- MVG Industries SAS
Breast Cancer
Rollover Study of Weekly Paclitaxel (BMS-181339) in Patients With Advanced Breast Cancer
The purpose of this study is to evaluate the safety and efficacy of continued administration of paclitaxel given weekly in subjects considered to need to continue treatment after completion of the preceding "Phase II Clinical…
- Trial name
- NCT00971945
- Testing
- Paclitaxel
- Where
- 4 sites in Japan
- Volunteers
- 6 people
- Sponsor
- Bristol-Myers Squibb
Adenocarcinoma
Adjuvant Epirubicin/Cytoxan Followed By A Taxane VS. Epirubicin/Taxane As Treatment For Node-Positive Breast Cancer
The purpose of this study is to compare two combinations of drugs, epirubicin given with a taxane (ET) or epirubicin given with cyclophosphamide (cytoxan) and followed by a taxane to see if one of the combinations is better at…
- Trial name
- NCT00140075
- Testing
- Epirubicin with Cyclophosphamide, followed by a Taxane, Epirubicin with a Taxane
- Where
- 54 sites in United States
- Volunteers
- 606 people
- Sponsor
- Pfizer
Metastatic Breast Cancer, HER2-negative Breast Cancer
Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.
Phase 1b/2 open-label trial of 225Ac-DOTATATE (RYZ101) in subjects with ER+, HER2-negative unresectable or metastatic breast cancer expressing SSTRs.
- Conditions
- Metastatic Breast Cancer, HER2-negative Breast Cancer, ER+ Breast Cancer, Advanced Breast Cancer
- Trial name
- TRACY-1 (NCT06590857)
- Testing
- RYZ101, Standard of Care Endocrine Therapy
- Where
- 31 sites in United States, Canada and 1 more
- Volunteers
- 64 people
- Sponsor
- RayzeBio, Inc.
Metastatic Breast Cancer in the Liver
Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease
The goal of this clinical trial is to learn if using a liver-directed therapy with high dose chemotherapy followed by approved cancer treatment to treat patients with breast cancer that has spread to the liver is safe and…
- Trial name
- DELUMA (NCT06875128)
- Testing
- Melphalan/HDS followed by Physician's choice of SOC (eribulin, vinorelbine, or capecitabine), Physician's choice of SOC (eribulin, vinorelbine, or capecitabine)
- Where
- 8 sites in United States, Italy and 2 more
- Volunteers
- 90 people
- Sponsor
- Delcath Systems Inc.
Leptomeningeal Metastases
Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative Breast Cancer
Leptomeningeal metastases (LM) is a lethal complication of malignant tumors, characterized by tumor cell invasion and proliferation within the subarachnoid space.
- Trial name
- NCT06462092
- Testing
- Sacituzumab Govitecan, Pemetrexed
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Guangzhou Medical University
Breast Cancer
Proteomics and Radiomics Research of Breast Cancer Markers in Tissue, Interstitial Fluid and Serum
The current study is a case control study involving comparisons of tissue interstitial fluid from breast cancer and adjacent non-cancerous tissue as well as that from benign breast lesion and its adjacent non-diseased tissue for…
- Trial name
- NCT01042548
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
Breast Cancer Lymphedema
Axillary Reverse Mapping (ARM) in Breast Cancer Surgery to Prevent Lymphedema. (ARMtrial)
Breast cancer related lymphedema (BCRL) is a debilitating and distressing condition affecting approximately one out of five breast cancer survivors.
- Trial name
- NCT03333226
- Testing
- Axillary Reverse Mapping (ARM)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University Hospital of Ferrara
Male Breast Cancer
Male breAsT cAncer preDisposition Factor: Creation of a Control Cohort 2
This is an interventional, prospective, single-center study designed to collect and describe genetic, environmental and psychosocial control data from male participants.
- Trial name
- MATADOR2 (NCT07558343)
- Testing
- Questionnaire completion, Genetic analysis (WES)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Institut Claudius Regaud
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