Clinical trials: Breast Tumour
Breast Cancer, Image Guided Biopsy
In Vivo Smart Biopsy Device Protocol In Radiology
This study is designed to demonstrate the feasibility of use of the Smart Biopsy Device in real clinical settings.
- Trial name
- NCT03914911
- Testing
- Smart Biopsy Device
- Where
- 2 sites in Israel
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Dune Medical Devices
HER2-negative Breast Cancer
Eribulin Combined With Anlotinib in Metastatic HER2 Negative Breast Cancer
This is a multicenter, phase II, open-label, single-arm investigator initiated trial to evaluate the efficacy and safety of eribulin mesylate combined with anlotinib in metastatic HER2 negative breast cancer patients.
- Trial name
- NCT04624711
- Testing
- Eribulin Mesylate, Anlotinib hydrochloride
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Breast Cancer
Autotaxin: a Potential Biomarker for Breast Cancer.
The goal of this clinical trial is to test the efficiency of Autotaxin (ATX) as a biomarker for breast cancer patients. The main questions it aims to answer are; is ATX a reliable tumor marker for breast cancer patients in…
- Trial name
- NCT05680311
- Testing
- measurement of serum autotaxin serum level
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Breast Cancer
Evaluating the Effects of Genetic Testing on Patients' Stress Levels
This prospective Medical College of Wisconsin Cancer Center study will evaluate stress levels in breast cancer patients undergoing genetic testing.
- Trial name
- NCT02783664
- Testing
- Questionnaires to Evaluate Anxiety Related to Genetic Testing
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Medical College of Wisconsin
Breast Cancer
Sorafenib and Paclitaxel in Treating Patients With Metastatic Breast Cancer
RATIONALE: Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Trial name
- NCT00622466
- Testing
- paclitaxel, sorafenib tosylate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Breast Cancer With Bone Metastasis
The Role of Bisphosphonate and Simvastatin Combination on Therapeutic Response in Breast Cancer With Bone Metastasis Via Dicckopf-1 Pathway
This randomised, double-blind, placebo-controlled pilot trial evaluated the therapeutic response of zoledronic acid combined with simvastatin in women with breast cancer and confirmed bone metastases.
- Trial name
- NCT07823751
- Testing
- Simvastatin, Zoledronic Acid (Zometa)
- Where
- Indonesia
- Volunteers
- 35 people
- Sponsor
- Universitas Indonesia
PIK3CA-Related Overgrowth Spectrum (PROS), Breast Cancer
Managed Access Programs for BYL719, Alpelisib
The purpose of this registration is to list Managed Access Programs (MAPs) related to BYL719, Alpelisib
- Trial name
- NCT04085653
- Testing
- alpelisib
- Sponsor
- Novartis Pharmaceuticals
Breast Cancer
Study of ISB 1302 (CD3 Bispecific Ab) in HER2-positive Metastatic Breast Cancer
The purpose of this study is to determine the safety profile, maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D) of single agent ISB1302 in subjects with HER2-positive metastatic breast cancer who have been…
- Trial name
- NCT03983395
- Testing
- ISB 1302 250 ng/kg, ISB 1302 325 ng/kg, ISB 1302 325 ng/kg-D1;425 ng/kg -D8,D15,D22
- Where
- 5 sites in United States
- Volunteers
- 1 people
- Sponsor
- Ichnos Sciences SA
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Treatment Decision Making in African American Women Diagnosed With Triple Negative Breast Cancer
This study evaluates what influences treatment decision-making in African American women with triple negative breast cancer. The study also aims to learn about the influence of information sources that support this…
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT05071677
- Testing
- Discussion, Interview, Survey Administration
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
Adapted Physical Activity Effect on Aerobic Function and Fatigue at Home in Patients With Breast Cancer Treated in Adjuvant or Neoadjuvant Phase
Physical exercise has been identified as a major item of many chronic diseases and cancer rehabilitation. It contributes to an improvement in the quality of life and to a decrease in the current treatment side effects and…
- Trial name
- APAC (NCT01795612)
- Testing
- physical activity
- Where
- France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Limoges
Metastatic Breast Cancer
Open Label Dose-Finding Study of TRC105 Plus Capecitabine for Metastatic Breast Cancer
The purpose of this study is to determine the recommended phase 2 dose and overall safety and tolerability of TRC105 when given in combination with capecitabine for the treatment of patients with progressive or recurrent…
- Trial name
- TRC105 (NCT01326481)
- Testing
- TRC105, Capecitabine
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Tracon Pharmaceuticals Inc.
Breast Neoplasm Female
Football Fitness After Breast Cancer
Late effects of breast cancer treatment are widely reported including deteriorating fitness, fatigue, loss of muscle and bone mass, and increased body fat percentage.
- Trial name
- FFABC (NCT03284567)
- Testing
- Football fitness
- Where
- Denmark
- Volunteers
- 69 people
- Sponsor
- University of Copenhagen
Breast Cancer
The Impact of Tamoxifen and Aromatase Inhibitors on Platelet Proteins
Single phlebotomy study involving women receiving tamoxifen or aromatase inhibitor therapy.
- Trial name
- NCT01341171
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Vermont
Pre-diabetes, Breast Cancer
Time Restricted Eating on Cancer Risk
Participants will be randomly assigned to either the time restricted feeding group with a daily eating period of 8 hours or the control group with a daily eating period of greater than or equal to 12 hours.
- Conditions
- Pre-diabetes, Breast Cancer, Time Restricted Feeding
- Trial name
- TREC (NCT05038137)
- Testing
- Time restricted feeding, Control
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Medical University of South Carolina
Stage IV Breast Cancer
Breast Stereotactic Radiotherapy to Primary Tumors in Metastatic Patients
This is a dose escalation study involving stage IV breast cancer patients not progressing after 6 months of first line systemic treatment.
- Trial name
- BoMB (NCT05229575)
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Campus Bio-Medico University
Metastatic Breast Cancer
Thalidomide Plus Chemotherapy Versus Chemotherapy Alone for Advanced Breast Cancer
Sixty advanced breast cancer patients are planed to enrolled in this clinical trial. Forty patients are enrolled into thalidomide plus chemotherapy group. Twenty patients are enrolled into chemotherapy alone group.
- Trial name
- NCT02649101
- Testing
- Thalidomide, Physician's choice chemotherapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhejiang Cancer Hospital
Early-Stage Breast Carcinoma
Surgical Trial to Evaluate the Impact of a Lymphoscintigraphy Prior to Sentinel Node Biopsy in Early Breast Cancer
Sentinel node biopsy is a well established tool for axillary staging in early breast cancer. So far the impact of a preoperative lymph node scintigraphy is unclear.
- Trial name
- NCT02481128
- Testing
- without preoperative access to lymphoscintigraphy findings
- Where
- 23 sites in Germany, Switzerland
- Volunteers
- 1,198 people
- Sponsor
- Kliniken Essen-Mitte
Breast Cancer
Nipple Areola Complex Conservation
96 patients were offered a nipple sparing mastectomy.
- Trial name
- NCT00641628
- Testing
- mastectomy
- Where
- Germany
- Sponsor
- Technical University of Munich
Progesterone Receptor Positive Tumor: Max 1 Line of Prior Chemotherapy, no Prior Hormone Therapy
Phase 1-2 Study of Onapristone in Patients With Progesterone Receptor Expressing Cancers
This is a multi-center, open-label, randomized, parallel group two-stage phase 1 study with a phase 2 expansion component in pts with recurrent or metastatic APRpos uterine endometrioid adenocarcinoma.
- Trial name
- NCT02052128
- Testing
- onapristone
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- Arno Therapeutics
Breast Cancer
Microwave Radiometry for the Diagnosis and Monitoring of Breast Cancer
A malignant tumor has higher temperature than normal tissue and the temperature of the tumor is dependent on the tumor growth rate. Thus tumor temperature is the universal indicator of tumor activity.
- Trial name
- RTM (NCT02514837)
- Testing
- RTM
- Sponsor
- University of Edinburgh
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