Clinical trials: Breastcancer
Breastcancer
A Comparative Study Between Oncoplastic Breast Surgery and Standard Conservative Surgery:Margin Status and Patient Satisfaction
This non randomized study is a comparative study between standard conservative breast surgery and oncoplastic surgery as regard margin status and patient satisfaction.
- Trial name
- NCT03012152
- Testing
- Standard conservative breast surgery, Oncoplastic breast surgery
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Breastcancer
Minimal Invasive Breast Cancer Excision Using the Breast Lesion Excision System Under Ultrasound Guidance
This study will assess whether it is feasible to remove small breast cancers completely using the Breast Lesion Excision System under Ultrasound guidance.
- Trial name
- BLES (NCT02975128)
- Testing
- BLES system and conventional lumpectomy
- Where
- 2 sites in Netherlands
- Volunteers
- 22 people
- Sponsor
- Radboud University Medical Center
Diffuse Large B-cell Lymphoma, Hodgkin Lymphoma
BMS_PD-L1_onco : Assessment of the PD-L1 Protein as a Biomarker in Oncology and Hematology
Diffuse large B-cell lymphomas (DLBCLs) represent 25 to 30% of adult non-Hodgkin lymphomas in western countries. DLBCLs are aggressive cancer but potentially curable with multi-agent chemotherapy.
- Conditions
- Diffuse Large B-cell Lymphoma, Hodgkin Lymphoma, Metastatic Breastcancer, Non-small Cell Lung Cancer
- Trial name
- BMS_PD-L1 (NCT01660776)
- Where
- 4 sites in France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Surgery, 75 Years Old and More
Place of Comprehensive Geriatric Assessment in Patients ≥ 75 Years Care, With Breast Cancer, After Screening With FOG (Oncology Geriatric Filter)
The risk of diagnosis of cancer increases with age, especially breast cancer in elderly women. Elderly population is heterogeneous, regarding physiological reserves, comorbidities, disability and geriatric conditions.
- Conditions
- Surgery, 75 Years Old and More, Female Breast Cancer
- Trial name
- NCT03059875
- Testing
- Medical consultation for a Standardized Geriatric Evaluation
- Where
- 6 sites in France
- Volunteers
- 79 people
- Sponsor
- Poitiers University Hospital
Breastcancer
The Efficacy and Safety of PEG-rhG-CSF（Pegylated Recombinant Human Granulocyte Colony Stimulating Factor)in Patients With Breast Cancer Who Were Treated With Intensive Chemotherapy
The purpose of the study is to evaluate the efficacy and safety of PEG-rhG-CSF in patients with breast cancer who were treated with intensive chemotherapy for prevention of neutrophil reduction.
- Trial name
- NCT02944604
- Testing
- PEG-rhG-CSF
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Peking University
Breastcancer
A Clinical Study to Determine the Pharmacokinetics of Oraxol in Breast Cancer Patients
This is a multicenter, open-label, single-arm PK study in patients for whom paclitaxel treatment is indicated.
- Trial name
- NCT03165955
- Testing
- Oraxol
- Where
- 6 sites in Taiwan
- Volunteers
- 28 people
- Sponsor
- Health Hope Pharma
Breastcancer
Trial Evaluating Role of Post Mastectomy Radiotherapy in Women With Node Negative Early Breast Cancer
Postmastectomy radiotherapy (PMRT) is unequivocally beneficial in reducing the recurrences as well as improving survival in node positive breast cancer patients.
- Trial name
- PMRT-NNBC (NCT02992574)
- Testing
- Post Mastectomy Radiation therapy
- Where
- 7 sites in India
- Volunteers
- 1,022 people
- Sponsor
- Tata Memorial Centre
Metastatic Breastcancer, Estrogen Receptor Positive Breast Cancer
A Phase II Study Evaluating the Role of Androgen Receptors as Targets for Therapy of Pre-treated Post-menopausal Patients With ER/PgR-negative/AR-positive or ER and/or PgRpositive/ AR-positive Metastatic Breast Cancer (ARTT)
A phase II non randomized study evaluating the role of Androgen Receptors as Targets for therapy of pre-treated postmenopausal patients with ER/PgR-negative/AR-positive or ER and/or PgR-positive/AR-positive metastatic breast…
- Conditions
- Metastatic Breastcancer, Estrogen Receptor Positive Breast Cancer, Estrogen Receptor Negative Neoplasm, Progesterone Receptor Positive Tumor
- Trial name
- ARTT (NCT02000375)
- Testing
- DHEA
- Where
- 8 sites in Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Lymphedema, Inflammatory Breast Cancer (IBC)
Prediction Of Lymphedema In Patients With Inflammatory BreastCancer Using Preoperative Bioimpedance Measurements
To find out whether the BIA test can help identify participants with IBC who are at risk for developing lymphedema.
- Conditions
- Lymphedema, Inflammatory Breast Cancer (IBC), Preoperative, Bioimpedance Measurement
- Trial name
- NCT07855627
- Testing
- Neoadjuvant therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer, Breast Neoplasms
Feasibility of a Preoperative, Multimodal Lifestyle Intervention in Patients With Breastcancer
The primary objective of this study is to investigate the feasibility of a multimodal prehabilitation programme consisting of MIET during neoadjuvant intravenous chemotherapy infusion, HITT and strength training during the last…
- Trial name
- APRIORI (NCT06266312)
- Testing
- A multimodal prehabilitation programme
- Where
- Netherlands
- Volunteers
- 11 people
- Sponsor
- Maastricht University Medical Center
Breastcancer, Invasive Breast Carcinoma by Gene Expression Profile
The Symphony Triple A Study: Using Symphony in Treatment Decisions Concerning Adjuvant Systemic Therapy
Rationale: Prediction of prognosis in patients with breast cancer is important to determine the indication for adjuvant chemo-, endocrine- and immunotherapy.
- Trial name
- Symphony (NCT02209857)
- Where
- 34 sites in Netherlands
- Volunteers
- 660 people
- Sponsor
- Diakonessenhuis, Utrecht
Bra, Breast Cancer Surgery
OptiBra Study, Optimal Postoperative Bra After Breastcancer Surgery
This study evaluates how two different types of postoperative bra 1) standard bra, soft VS 2) compression bra compression after breast cancer surgery affect pain, seroma, other symptoms and complications, and the womans…
- Conditions
- Bra, Breast Cancer Surgery, Complication, Compression
- Trial name
- NCT04059835
- Testing
- OptiBra study
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska University Hospital
Breast Cancer
Radiotherapy After Primary Chemotherapy for Breastcancer
The primary aim of the study is to evaluate the 5 yr locoregional recurrence rate (LRR) in cT1-2cN0-1(cytology/histology and/or positive SN, excluding patients with > 3 pathologic axillary nodes on imaging) breast cancer…
- Trial name
- RAPCHEM (NCT01279304)
- Testing
- radiation - no radiation see intervention description, radiation: see intervention description
- Where
- 6 sites in Netherlands
- Volunteers
- 851 people
- Sponsor
- Maastricht Radiation Oncology
Breastcancer
Feasibility of Breast Cancer Risk Evaluation in Women From the General Population
This study aims to evaluate the feasibility (acceptability) of a consultation dedicated to informing women about their risk of breast cancer and the screening methods recommended for them according to the recommendations in force…
- Trial name
- RIVIERA (NCT02997384)
- Testing
- Information
- Where
- France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Breastcancer
Outcome of 15 Versus 5 Fractions in Adjuvant Breast Radiotherapy in Women Over 65 Years
This study will evaluate the effect of highly accelerated external beam radiotherapy (EBRT) in 5 fractions over 10 days compared to 15 fractions over 3 weeks for early as well as locally-advanced stage breast cancer.
- Trial name
- HAI-5-III (NCT03121248)
- Testing
- WBI 5 fractions, WBI 15 fractions, LNI 5 fractions
- Where
- Belgium
- Volunteers
- 144 people
- Sponsor
- University Hospital, Ghent
Breastcancer, Emotional Disorder
Presential Vs Online Group-based Psychosocial Treatment for Breast Cancer Survivors.
This multicenter study is a sequential RCT which aims to prove, in the first stage, the efficacy of a face-to-face Positive Psychotherapy in Cancer (PPC) group compared to a Cognitive Behavioral Stress Management (CBSM) group.
- Conditions
- Breastcancer, Emotional Disorder, Distress
- Trial name
- PSONLINE (NCT03010371)
- Testing
- Positive Psychotherapy, Positive Online Psychotherapy, Cognitive Behavioral Therapy
- Where
- Spain
- Volunteers
- 365 people
- Sponsor
- Institut Català d'Oncologia
Breast Cancer
Supervised Exercise to Promote Infiltration of NK-cells Into the Tumor
'Supervised exercise to PRomote Infiltration of NK-cells into the Tumor? The objective of this feasibility study is to 1) study trial feasibility in terms of patient enrollment and the percentage of tumor biopsies that can be…
- Trial name
- SPRINT (NCT04704856)
- Testing
- Supervised exercise
- Where
- 2 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- Amsterdam UMC, location VUmc
Breastcancer, Breast Neoplasm
SV-BR-1-GM in Metastatic or Locally Recurrent Breast Cancer
This is a single arm, open label study of SV-BR-1-GM, a targeted immunotherapy for breast cancer. Eligible patients will have histological confirmation of breast cancer with recurrent and/or metastatic lesions.
- Trial name
- NCT03066947
- Testing
- SV-BR-1-GM, Cyclophosphamide, Interferon-alpha-2b
- Where
- 5 sites in United States
- Volunteers
- 24 people
- Sponsor
- BriaCell Therapeutics Corporation
Lymph Node, Breastcancer
CK19 Combined With Contrast-enhanced Ultrasound: a Prediction System on Axillary Lymph Node Metastasis in Breast Cancer
To establish a predicting system on axillary lymph node metastasis based on peripheral blood CK19mRNA and contrast-enhanced ultrasound.
- Trial name
- CK-CEUS (NCT02992067)
- Where
- China
- Volunteers
- 359 people
- Sponsor
- Zhejiang Cancer Hospital
Breastcancer
Identification of C7; Evaluations of 2 Sonographic Methods Using a Transverse and a Sagittal Scan.
To determine the accuracy of two techniques (transverse scan and sagittal scan) using ultrasonography to identify C7 spinous process compare to the fluoroscope (standard technique)
- Trial name
- NCT03012893
- Testing
- Ultrasound sagittal scan, Ultrasound transverse scan, Fluoroscopic technique
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University