Clinical trials: Breath Analysis
Glucose-Galactose Malabsorption, Enteropathy
Labelled Carbon Sucrose Breath Test (13C-SBT) as a Marker of Environmental Enteropathy
Linear growth failure, a manifestation of chronic undernutrition in early childhood, is a recalcitrant problem in resource constrained settings.
- Conditions
- Glucose-Galactose Malabsorption, Enteropathy, Malnutrition, Child, Intestinal Permeability
- Trial name
- SBT4EE (NCT04109352)
- Where
- 9 sites in Australia, Bangladesh and 6 more
- Volunteers
- 600 people
- Sponsor
- University of Virginia
Lung Cancer
Analysis of Volatile Chemicals in Lung Cancer Screen-Eligible Subjects Using Infrared Spectroscopy
The aim of this study is to sample and analyze volatile organic compounds (VOCs) from a high-risk population of subjects eligible for lung cancer screening as defined by the US Preventive Services Task Force (USPSTF) guidelines.
- Trial name
- NCT05174468
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Breathe BioMedical Inc
Mamma Carcinoma
Breath Gas Analysis for the Diagnosis of Breast Cancer
The volatile content of the exhaled breath gas of mamma carcinoma patients will be chemically analyzed by proton-transfer-reaction time of flight mass spectrometry.
- Trial name
- NCT01105468
- Testing
- Breath Collecting Unit
- Where
- Austria
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Ionimed Analytik GmbH
Gastroparesis
GEBT Telehealth Administration Usability Study
The purpose of this study is to establish the usability of a telehealth platform for the administration of GEBT.
- Trial name
- NCT04684992
- Testing
- GEBT Telehealth Administration Usability
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairn Diagnostics
Gastric Acid-related Diseases, Healthy
Comparison Study Between C13-CAC Breath Test and 24-hour Gastric pH Monitoring
The purpose of this study is to compare C13-CAC Breath Test with 24-hour Gastric pH Monitoring in Patients with Gastric Acid-related Diseases and Healthy Volunteers
- Trial name
- NCT02225067
- Testing
- Calcium (13C)Carbonate
- Where
- Japan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Malnutrition
Breath Analysis & Malnutrition
The purpose of this research study is to understand how breath is related to nutritional status. The procedures involved in this study include blood and breath sampling, questionnaires about health history, medications…
- Trial name
- BAM-S (NCT06115148)
- Testing
- Feeding, Fasting
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Non-small Cell Lung Cancer, Pulmonary Nodule, Multiple
Breath Combined With CT for Diagnoses of Pulmonary Nodules
Pulmonary nodules diagnosis using breath test of volatile organic compound (VOC) is in its infancy. The accuracy of VOC analysis in diagnosing malignant pulmonary nodules varies cross the published studies.
- Trial name
- NCT04948047
- Testing
- Pathological examinations as the golden diagnosis criteria, Breath test combined with computed tomography
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Peking University People's Hospital
Exhaled Breath Pattern After Medication Intake, in OSA Patients, or Other Pulmonary Diseases
Exhaled Breath Analysis in Human Subjects
Identification of exhaled breath pattern of human subjects
- Trial name
- NCT05456009
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Fatty Liver
Palmitate Breath Test to Assess Fatty Acid Oxidation in Non Alcoholic Fatty Liver Disease (NAFLD)
Background: Non-alcoholic fatty liver disease (NAFLD) is a common cause of abnormal liver tests. It is closely linked to health problems like obesity and diabetes.
- Trial name
- NCT02363309
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Gastroparesis, Functional Dyspepsia
Effects of Liraglutide on Body Surface Gastric Mapping
Aim 1: To investigate, in healthy participants, the effect of liraglutide injection on gastric electrophysiology (as measured by body surface gastric mapping using the Gastric Alimetry device) during an 13-dayramping dose of…
- Conditions
- Gastroparesis, Functional Dyspepsia, Chronic Nausea and Vomiting Syndrome, Healthy
- Trial name
- NCT06500130
- Testing
- Body Surface Gastric Mapping
- Where
- New Zealand
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Alimetry
Irritable Bowel Syndrome
Efficacy of Rifaximin to Treat Diarrhea-predominant Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a common disease and the pathogenesis of this disease includes central and peripheral mechanisms.
- Trial name
- NCT02565654
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Breast Cancer, Colon Cancer
Breath Testing for Breast and Colon Cancer Diagnosis- NaNose Study
The concept of breath testing for various diseases has been around since ancient greece. It has been hypothesized that cancer is generating a unique pattern of compounds in patients' breath.
- Trial name
- NCT01292369
- Where
- 2 sites in Israel
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Pulmonary Edema
Power Spectral Analysis of Breath Sound in Pulmonary Edema
Pulmonary edema can be classified into "cardiogenic pulmonary edema" and "non-cardiogenic pulmonary edema" according to the underlying etiology.
- Trial name
- NCT00767195
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Tuberculosis, Gastric Cancer
Volatiles in Breath and Headspace Analysis - Diagnostic Markers
Detection of Volatile Organic Compounds (VOC) directly from tissue by headspace analysis (skin, surgery material, other tissue) and exhaled breath is feasible using affordable user-friendly novel nano-chemo sensors that can…
- Conditions
- Tuberculosis, Gastric Cancer, Peptic Ulcer, Atrophic Gastritis
- Trial name
- Volatolome (NCT03228095)
- Testing
- VOC detection in breath and in skin headspace, Breath sampling, Upper endoscopy with biopsies
- Where
- Latvia
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Latvia
Colorectal Cancer, Colorectal Polyp
VOCs vs FIT for Colorectal Cancer Screening
Endogenous breath VOCs (Volatile Organic Compounds) are present in various excreted biological materials (urine, blood, faeces an breath) and their analysis offers a possibility for cancer screening.
- Trial name
- NCT04407416
- Testing
- Breath sampling
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Nutritional and Metabolic Diseases
Exploratory Study of Volatile Organic Compounds in Alveolar Breath
The purpose of this secondary analysis is to identify breath signatures associated with idiopathic malodor conditions.
- Trial name
- VOCs (NCT03451994)
- Testing
- Breath test
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 23 people
- Sponsor
- Mebo Research, Inc.
Congenital Sucrase-Isomaltase Deficiency
Adult Pilot Study for Reference Ranges and Optimal Cut-offs for the Sucrose Challenge Test and Sucrose Breath Test
An adult pilot study to establish the normal reference range and optimal cutoffs for the oral 50g Sucrose Challenge Test (SCT) and the 50g 13C-Sucrose Breath Test (CBT) for patients with CSID and healthy controls.
- Trial name
- NCT05045495
- Testing
- Sucrose Hydrogen Methane Breath Test
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- QOL Medical, LLC
Tobacco Use Cessation
An Evidence Based Smoking Cessation Program for Persons Living With HIV/AIDS (Project Legacy)
The goal of this research study is to compare 2 different phone-based programs for quitting smoking for people with HIV/AIDS.
- Trial name
- NCT02029612
- Testing
- Nicotine Patch, Phone Counseling, Questionnaires
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Gastroparesis
Establishing a Pediatric Reference Range for the 13C-Spirulina Gastric Emptying Breath Test (GEBT)
The goal of this clinical trial is to define the normal response to the 13C-Spirulina Gastric Emptying Breath Test (GEBT) in children, so that we can use this test to help diagnose children that are suspected of having a…
- Trial name
- NCT06004596
- Testing
- 13C-Spirulina Gastric Emptying Breath Test (GEBT), 13C-Spirulina Gastric Emptying Breath Test (GEBT) - repeat
- Where
- 3 sites in United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Cairn Diagnostics
Asthma, Chronic Obstructive Lung Disease
The Identification of Different Lung Diseases by Analysis of Volatile Organic Compounds in Breath Samples
The investigators assume that by analysis of different volatile organic compounds in the breath, using nanotechnology, the investigators will be able to identify a unique respiratory signature of different diseases including…
- Trial name
- PHNOSE (NCT01631162)
- Testing
- Breath sample in all patients
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center