Clinical trials: Breath Analysis
NAFLD
Prediction of Severity of Liver Disease Non Alcoholic Fatty Liver Disease in Patients With Suspected NAFLD by a 13C Octanoate Breath Test
The Exalenz clinical investigation is a multicenter, non-randomized, blinded, study of the ¹³C-Octanaote breath test (OBT). The OBT is a non-invasive test for evaluation of disease severity in patients with suspected non…
- Trial name
- NCT01281059
- Testing
- BreathID - Breath Test - 13C Octanoate
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Gastrointestinal Hemorrhage, Volatile Organic Compounds
Volatile Organic Compounds (VOCs) of Exhaled Breath in Patients With GI Bleeding
Cross sectional case-control study investigating the difference of volatile organic compound in the exhaled breath of the patients with GI bleeding and normal population.
- Trial name
- NCT04226079
- Testing
- Collection of exhaled breath
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Covid19
Evaluation of Anti-COVID 19 Pfizer Vaccination Effect on COVID 19 Detection Using Breath Analysis
The objective of this study will be to evaluate the effect of vaccination on breath VOC content. By capturing and analyzing the breath of anti-COVID-19 vaccinated subjects during the period of antibody production, the…
- Trial name
- COVID-19 (NCT04842708)
- Testing
- vaccination against COVID19
- Where
- Israel
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Scentech Medical Technologies Ltd
Thoracic Surgery
Analysis of Breath Sound During Thoracic Surgery
In modern thoracic surgery, double-lumen endobronchial tube (DLET) is the first choice for intubation. One lung ventilation can be perfectly performed by DLET, with the benefit of maintaining adequate gas exchange and…
- Trial name
- NCT05250635
- Testing
- electronic stethoscope
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Respiratory Tract Infections, Hematologic Diseases
Rapid Analysis of Infections by Spectrometry of Exhaled Breath
To quantify the diagnostic, prognostic and therapeutic value of spectrometric analysis of exhaled breath from hematological patients with respiratory infection.
- Trial name
- RAISE (NCT03299608)
- Testing
- Breath analysis
- Where
- Belgium
- Volunteers
- 246 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Diabetes Mellitus, Type 2
Exogenous Glucose Oxidation Breath Test
The purpose of this study is to determine if oxidation of 13C glucose to 13CO2 is changed in type 2 diabetic patients.
- Trial name
- EGOBT (NCT01846767)
- Testing
- Oral glucose breath test
- Where
- Ireland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Human Energy Expenditure
Measurements of Water in Breath and Saliva
This study proposes to demonstrate the feasibility of measuring 2H:1H and 18O:16O in saliva and breath by comparing the natural abundances of 2H:1H and 18O:16O in saliva and urine of un-dosed humans.
- Trial name
- NCT03233256
- Testing
- Feasibility of measuring 2H:1H and 18O:16O in saliva and breath.
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Diet, Healthy, Breath Analysis
Why Calories Are Not the Same - a Gut Explanation?
The aim of this study is to understand how the gut microbiome influences how much dietary energy humans excrete via feces. This study is based on the hypothesis that levels of methane in exhaled breath represent two different gut…
- Trial name
- GutEnergy (NCT06932666)
- Testing
- Diet A group, Diet B group
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Metabolic Syndrome, Obesity & Overweight
Breath Mass Spectrometry in Metabolic Syndrome and Metabolically Healthy Obesity
This study aims to develop a non-invasive diagnostic method for metabolic syndrome (MetS) and metabolically healthy obesity (MHO) through analysis of exhaled air.
- Conditions
- Metabolic Syndrome, Obesity & Overweight, Metabolically Healthy Obesity
- Trial name
- NCT07330297
- Testing
- Breath Sampling and Analysis by PTR-MS
- Where
- Russia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Gastroparesis
GEBT Lot-to-Lot and Biological Variability
The purpose of this study is to collect information regarding lot-to-lot variability in 13C-Spirulina test meal lets and within-subject biological variability.
- Trial name
- NCT04772261
- Testing
- 13C-Spirulina GEBT
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cairn Diagnostics
Metabolic State, Breath Analysis, NA-Nose
Detection of PCOS by Sensors Array
Detection of metabolic state of women with polycystic ovary using NA-Nose.
- Trial name
- NCT03046537
- Testing
- Breath test
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Non-alcoholic Fatty Liver Disease (NAFLD)
Elucidating Hepatic Metabolism in Non-alcoholic Fatty Liver Disease
The goal of this observational, cross-sectional, case-control clinical study is to investigate the metabolic adaptations underlying the progression of nonalcoholic fatty liver disease (NAFLD), and to test the hypothesis that…
- Trial name
- ECHO (NCT06942312)
- Testing
- Ketoisocaproic acid breath test, Ammonium Chloride, Bicarbonate de sodium
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Lung Cancer, Breast Cancer
Distinction Between Lung Cancer and Gynecological Cancers by Canine Scent Detection
Previous studies have shown that specially trained sniffer dogs are capable to discriminate breath samples of patients with lung cancer and healthy individuals.
- Conditions
- Lung Cancer, Breast Cancer, Ovarian Cancer
- Trial name
- NCT01383408
- Testing
- exhalation analysis of breath sample
- Where
- 2 sites in Germany
- Volunteers
- 752 people, healthy volunteers welcome
- Sponsor
- Schillerhoehe Hospital
General Anesthesia, Intraoperative Monitoring
Analysis of Breath Sounds During Surgery
This study aims to analyze breath sounds during surgery by using electronic stethoscope sensors attached to patients under general anesthesia.
- Conditions
- General Anesthesia, Intraoperative Monitoring, Respiratory Sounds
- Trial name
- BREATHSOUND (NCT07280546)
- Testing
- Electronic stethoscope monitoring
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Infection, Community-Acquired, Communicable Disease
Infection Detection by Breath Analysis
The purpose of this feasibility study is to test a device which analyzes breath and may allow doctors and health professionals to immediately determine if an ill patient has a specific type of bacterial infection.
- Conditions
- Infection, Community-Acquired, Communicable Disease, Respiratory Infection
- Trial name
- NCT02981550
- Sponsor
- BreathTec Biomedical Inc.
Inactivity, Physical, Aging
Oral 'Breath Test' to Measure Anabolic Sensitivity to a Protein Meal Across the Age and Physical Activity Spectrum
The purpose of this study is to determine how anabolic sensitivity, in response to the ingestion of a liquid protein meal, differs across the lifespan, between biological sexes, and with varying physical activity levels.
- Conditions
- Inactivity, Physical, Aging, Healthy Aging, Growth & Development
- Trial name
- NFRF (NCT06744491)
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Helicobacter Pylori, Early Gastric Cancer
Helicobacter Pylori Infection Status and Pathological Features for Predicting Gastric Cancer Biological Behavior and Prognosis: A Real-World Observational Study
This multicenter retrospective and prospective real-world observational study will evaluate the relationship of Helicobacter pylori (H.
- Trial name
- NCT07724496
- Testing
- 13C-Urea Breath Test, Serum Helicobacter pylori Antibody Testing, Pathological Assessment of Gastric Tissue
- Where
- 3 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Chinese PLA General Hospital
Obstructive Sleep Apnea
Validity of a Supersimplified Device for Diagnosis of Patients With Suspected Obstructive Sleep Apnoea-hypopnoea (OSAH)
The diagnosis of OSASH requires expensive sleep tests that generate long waiting lists, so we need simplified and rapid diagnostic tools.
- Trial name
- NCT01347398
- Testing
- PSG, MicroMESAM system
- Volunteers
- 815 people
- Sponsor
- Basque Health Service
Exhaled Breath, Mass Spectrometry
Breath Analysis in Healthy Controls
The purpose of this study is to detect a specific profile of breath in healthy subjects by an untargeted metabolomic study using exhaled breath analysis by mass spectrometry.
- Conditions
- Exhaled Breath, Mass Spectrometry, Healthy Subjects
- Trial name
- NCT02595632
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Weight Loss
Gastric Emptying Using Two Imaging Methods for Those Who Have Undergone POSE2 Weight Loss Procedure
The purpose of this study is to compare a less invasive breath test against the current standard for assessing gastric (stomach) emptying.
- Trial name
- NCT04502732
- Testing
- NSSM and GEBT
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Mayo Clinic