Clinical trials: Breath Test
Chronic Liver Disease
BreathID 13C-Methacetin Breath Test for Detecting Cirrhosis
This trial is a pivotal trial to validate the use of a 13 C labeled substrate called methacetin and the BreathID automatic breath testing system, for determination of cirrhosis in patients with chronic liver disease.
- Trial name
- MBT (NCT00736840)
- Testing
- c13 methacetin solution with breath analyzer
- Where
- 11 sites in United States, Israel
- Volunteers
- 414 people
- Sponsor
- Meridian Bioscience, Inc.
SARS-CoV-2 Infection
Breath Analysis for SARS-CoV-2 in Infected and Healthy Subjects
Recently published studies could demonstrate that detection of specific biomarkers in breath could be applied for the diagnosis of SARS-CoV-2.
- Trial name
- NCT04547114
- Testing
- Multicapillary column coupled ion mobility spectrometry
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Klinikum Bayreuth GmbH
Colorectal Cancer, Pancreatic Cancer
Chemical Profiling of Colorectal and Pancreatic Cancers Using Breath Analysis - Feasibility Study
Detection of Colorectal and Pancreatic Cancers Using Breath Analysis - Feasibility Study
- Trial name
- Cancer (NCT05400408)
- Testing
- VOX
- Where
- Israel
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Scentech Medical Technologies Ltd
Covid19
Evaluation of Anti-COVID 19 Pfizer Vaccination Effect on COVID 19 Detection Using Breath Analysis
The objective of this study will be to evaluate the effect of vaccination on breath VOC content. By capturing and analyzing the breath of anti-COVID-19 vaccinated subjects during the period of antibody production, the…
- Trial name
- COVID-19 (NCT04842708)
- Testing
- vaccination against COVID19
- Where
- Israel
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Scentech Medical Technologies Ltd
Gastric Acid-related Diseases, Healthy
Comparison Study Between C13-CAC Breath Test and 24-hour Gastric pH Monitoring
The purpose of this study is to compare C13-CAC Breath Test with 24-hour Gastric pH Monitoring in Patients with Gastric Acid-related Diseases and Healthy Volunteers
- Trial name
- NCT02225067
- Testing
- Calcium (13C)Carbonate
- Where
- Japan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Gastroparesis
Evaluation of Single Doses of GSK962040 in Critically Ill Patients With Enteral Feed Intolerance
The aims of MOT112571 are to assess the pharmacodynamic effects, safety, tolerability, pharmacokinetics, and potential therapeutic benefit of single doses of GSK962040 in critically ill patients with delayed gastric emptying and…
- Trial name
- NCT01039805
- Testing
- GSK962040 (50 mg), GSK962040 (75 mg)
- Where
- Australia
- Volunteers
- 34 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Type 2, Liver Diseases
Validate Smart Breath Analyzer as Screening Tool for Diabetic, Hepatic, Renal, Lung, and Other Metabolic Disorders
This is a prospective, multicentric, non-treatment study to build and validate a portable, non-invasive smart breath analyzer that can screen underlying health issues using exhaled breath.
- Conditions
- Diabetes Mellitus, Type 2, Liver Diseases, Kidney Diseases, Lung Diseases
- Trial name
- RESPYR-SBA (NCT07646015)
- Where
- India
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Respyr
Helicobacter Pylori, Safety
PyloPlus Urea Breath Test System Pediatric Safety and Efficacy Study
This is a multi-center, non-randomized, open label study. Subjects will be enrolled on a walk-in basis. Screening data will be reviewed to determine subject eligibility.
- Conditions
- Helicobacter Pylori, Safety, Efficacy
- Trial name
- NCT05276557
- Testing
- PyloPlus Urea Breath Test System, Stool Antigen Test
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ARJ Medical, Inc.
Non-Alcoholic Steatohepatitis
BREATHID Octanoate Breath Test With or Without Methacetin Breath Test for Correlation With Biopsy in NASH
This study's aim is to develop an algorithm for the ¹³C-Octanoate Breath Test with or without the ¹³C-Methacetin Breath Test (OBT and MBT respectively) for correlation with histological findings associated with of Non-Alcoholic…
- Trial name
- NCT02314026
- Testing
- Suspected NASH BreathID test with 13C-Octanoate, Suspected NASH Breath test with 13C Methacetin
- Where
- 11 sites in United States, Belgium and 2 more
- Volunteers
- 140 people
- Sponsor
- Meridian Bioscience, Inc.
Lung Neoplasms
Breath Test for Early Detection of Lung Cancer
To demonstrate and validate a breath test for detection of early stage lung cancer that could potentially reduce number of deaths.
- Trial name
- NCT00639067
- Testing
- Breath Collection Apparatus
- Where
- 4 sites in United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Menssana Research, Inc.
Pulmonary Disease, Chronic Obstructive
Prednisolone Novel Endpoint Study in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Prednisolone will be used as a model medication to identify new clinical outcomes for future evaluation of new therapies in short-term studies (up to 4 weeks) in patients with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT00379730
- Testing
- Prednisolone
- Where
- 5 sites in Argentina, Chile and 2 more
- Volunteers
- 90 people
- Sponsor
- GlaxoSmithKline
Lactose Intolerance
Effect of a Combination of Lactase and L. Salivarius DSM 34078 in Individuals With Lactose Intolerance
The goal of this clinical trial is to test whether a new combination of lactase and bacterial strain (L. Salivarius DSM 34078) can provide longer lasting beneficial effects on lactose digestion and gastrointestinal symptoms…
- Trial name
- NCT06107088
- Testing
- Active 1, Active 2, Active 3
- Where
- Germany
- Volunteers
- 76 people
- Sponsor
- Novozymes A/S
Irritable Bowel Syndrome
Sucrose Breath Test to Determine Intestinal Permeability in IBS
Irritable Bowel Syndrome (IBS) is a growing clinical diagnosis affecting 10-20% of the US population. While current diagnostic criteria aids in correctly diagnosing IBS, the cause of the disease still remains unclear.
- Trial name
- NCT01674088
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Metabolic Solutions Inc.
Gastroparesis
Dose Response of 28 Days of Dosing of GSK962040 in Type I and II Diabetic Male and Female Subjects With Gastroparesis
GSK962040 is a novel small molecule motilin agonist. The Phase I studies (MOT107043 and MOT109681) demonstrated that single doses of GSK962040 up to 150 mg and repeat dosing of up to 125 mg/day for 14 days were well tolerated…
- Trial name
- NCT01262898
- Testing
- GSK962040 (5 mg tablet), GSK962040 (25 mg tablet), GSK962040 (125 mg tablet)
- Where
- 22 sites in United States, Australia and 4 more
- Volunteers
- 79 people
- Sponsor
- GlaxoSmithKline
Lung Cancer, Non Small Cell Lung Cancer
Breath Analysis in Early Stage Lung Cancer Using Infrared Spectroscopy
The aim of this study is to sample and analyze volatile organic compounds (VOCs) from lung cancer patients and individuals without lung cancer ("healthy" controls).
- Trial name
- NCT04556435
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Breathe BioMedical Inc
Infection, Community-Acquired, Communicable Disease
Infection Detection by Breath Analysis
The purpose of this feasibility study is to test a device which analyzes breath and may allow doctors and health professionals to immediately determine if an ill patient has a specific type of bacterial infection.
- Conditions
- Infection, Community-Acquired, Communicable Disease, Respiratory Infection
- Trial name
- NCT02981550
- Sponsor
- BreathTec Biomedical Inc.
Gastroparesis
Establishing a Pediatric Reference Range for the 13C-Spirulina Gastric Emptying Breath Test (GEBT)
The goal of this clinical trial is to define the normal response to the 13C-Spirulina Gastric Emptying Breath Test (GEBT) in children, so that we can use this test to help diagnose children that are suspected of having a…
- Trial name
- NCT06004596
- Testing
- 13C-Spirulina Gastric Emptying Breath Test (GEBT), 13C-Spirulina Gastric Emptying Breath Test (GEBT) - repeat
- Where
- 3 sites in United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Cairn Diagnostics
NASH - Nonalcoholic Steatohepatitis
Companion Protocol for ¹³C-Methacetin Breath Tests in BMS: NCT03486899, NCT03486912 Referenced Trials
This is a companion study assessing the ¹³C-Methacetin Breath Test (MBT) in subjects participating in the Bristol Myers-Squibb (BMS) NCT03486899 and NCT03486912 referenced studies using study drug BMS-986036.
- Trial name
- NCT03611101
- Testing
- ¹³C-Methacetin Breath Test, BMS-986036, BreathID MCS device
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Meridian Bioscience, Inc.
COVID-19
The Measurement of Chemicals in Exhaled Breath Can Identify If a Person is Infected with COVID-19
The type and number of chemicals in exhaled breath are different in people with infection as compared to those without infection. In this study, the breath of people with and without COVID infection will be measured.
- Trial name
- NCT06571136
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- N5 Sensors
Decompensated Cirrhosis
Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-17
This study is a companion protocol that will use the data generated by Conatus' study of emricasan under protocol IDN-6556-17.The IDN-6556-17 study is a Phase 2, multicenter, double-blind, placebo-controlled trial of Emricasan in…
- Trial name
- NCT03462576
- Testing
- Methacetin Breath Test, Emricasan
- Where
- United States
- Volunteers
- 199 people
- Sponsor
- Meridian Bioscience, Inc.