Clinical trials: Breath Test
Sepsis
Sepsis, Severe Sepsis and Septic Shock Detection by Breath Analysis
Breath samples will be collected from patients suspected of sepsis/severe sepsis or septic shock according to hospital sepsis screening criteria in the Emergency Department.
- Trial name
- NCT03497182
- Testing
- Breath sample collection
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Landon Pediatric Foundation
Insulin Resistance, Type 1 Diabetes
Validation of a 13C Glucose Breath Test Compared With the Euglycaemic Clamp Test
Insulin resistance can be assessed by the euglycaemic clamp technique. To date, this is the golden standard, but it is not suited for clinical practice. A 13C glucose breath test will be tested as a valid alternative.
- Trial name
- BRECLAIR (NCT04623320)
- Testing
- euglycaemic clamp test, 13C glucose breath test
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Hospital, Antwerp
Chronic Mesenteric Ischemia
Promoting Early Diagnosis of Chronic Mesenteric Ischemia
CMI is an incapacitating disease and timely diagnosis remains problematic. Despite the substantial compensatory capacity of the mesenteric circulation CMI is relatively common, its incidence being comparable to other well-known…
- Trial name
- PROMISE (NCT05735002)
- Testing
- 13C-butyrate breath test
- Where
- 4 sites in Netherlands
- Volunteers
- 296 people
- Sponsor
- Erasmus Medical Center
Gastroparesis
GEBT Lot-to-Lot and Biological Variability
The purpose of this study is to collect information regarding lot-to-lot variability in 13C-Spirulina test meal lets and within-subject biological variability.
- Trial name
- NCT04772261
- Testing
- 13C-Spirulina GEBT
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cairn Diagnostics
SARS-CoV-2 Infection, Covid19
Breath Analysis of Patients Diagnosed With COVID-19 Using Infrared Spectroscopy
To analyze Volatile Organic Compounds (VOCs) in the breath of patients with SARS-CoV-2 and controls in SARS-CoV-2 breath specimens.
- Trial name
- BREATH (NCT04867213)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- McMaster University
NASH - Nonalcoholic Steatohepatitis, Cirrhosis
Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14
To validate the ability of the Methacetin Breath Test (MBT) to detect clinically significant portal hypertension (CSPH)/severe portal hypertension (SPH) defined as hepatic venous pressure gradient (HVPG) ≥ 10 mmHg and HVPG ≥ 12…
- Conditions
- NASH - Nonalcoholic Steatohepatitis, Cirrhosis, Portal Hypertension
- Trial name
- NCT03439189
- Testing
- Methacetin Breath Test, Emricasan
- Where
- France
- Volunteers
- 343 people
- Sponsor
- Meridian Bioscience, Inc.
Liver Diseases, Liver Cancer
Breath Analysis Based Disease Biomarkers
The purpose of the study is to develop a clinical test based on breath analysis that can be used for disease diagnosis or prognosis.
- Conditions
- Liver Diseases, Liver Cancer, COVID19
- Trial name
- NCT04341012
- Testing
- Collection of breath sample
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Malabsorption
Investigate the Breath Hydrogen Exhalation After a Test Meal Containing Isomaltulose or Sucrose in Infants
The study shall investigate whether isomaltulose is digested and absorbed to a comparable degree like other carbohydrates (CHO) used as ingredients for this age group (e.g.
- Trial name
- NCT02247102
- Testing
- Isomaltulose, Sucrose
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Quality of Life
Impact of Different Carbohydrate Feedings on a Hydrogen Breath Curve and Self-reported Gastrointestinal Complaints
GI distress is widely prevalent among athletes, ranging from 30 to 90% in recreationally and professionally active athletes. As the recipient of nutrients, the gastrointestinal (GI) tract plays an important role in athleticism.
- Trial name
- NCT06648967
- Testing
- Supplementation with a multi-ingredient whey supplement
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Breath Test
HOspital Versus Primary Care Breath Test Environment (HOPE) Study
Through the HOPE study, the intention would be to determine whether exhaled breath volatile organic compound (VOC) profiles in Primary care differ from Secondary care.
- Trial name
- HOPE (NCT06611293)
- Testing
- Breath test
- Where
- 2 sites in United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Imperial College London
H Pylori Infection Eradication, Antibiotics Therapeutic Strategies
Therapeutic Trial Comparing Triple Therapy Guided by the PCR Detection of Clarithromycin Resistance vs Empiric Concomitant Quadruple Therapy for Helicobacter Pylori Infection
The H pylori infection remains a public health problem. The eradication rate with the first line triple therapy (PPI-amoxicillin-clarithromycin) is insufficient (estimated at 70%) due to the frequency of resistance to…
- Conditions
- H Pylori Infection Eradication, Antibiotics Therapeutic Strategies, H Pylori Eradication
- Trial name
- Hepysé (NCT02576236)
- Testing
- Quadruple concomitant therapy treatment, Triple therapy guided by the result of the molecular resistance test
- Where
- France
- Volunteers
- 2,500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cancer of the Breast, Cancer of Stomach
Vocorder Device Validation in Clinical Settings - Continuous Monitoring of Individuals (Vocorder Clinical Validation-VCV)
This is performed under Vocorder project that is Co-Funded by the European Union. (Grant Agreement 101115442 VOCORDER HORIZON EIC-2022-PATHFINDERCHALLENGE-01).
- Conditions
- Cancer of the Breast, Cancer of Stomach, Colon Cancer, Lung Cancers
- Trial name
- VCV (NCT06711939)
- Where
- Greece
- Volunteers
- 515 people, healthy volunteers welcome
- Sponsor
- Mitera Hospital
Exhaled Breath Pattern After Medication Intake, in OSA Patients, or Other Pulmonary Diseases
Exhaled Breath Analysis in Human Subjects
Identification of exhaled breath pattern of human subjects
- Trial name
- NCT05456009
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Small Bowel Disease, Motility Disorder
Study of Oro-cecal Transit Time in Healthy Subjects Using Scintigraphy and Lactulose Hydrogen Breath Test.
Radionuclide scintigraphy is the gold standard technique to interpret OCTT but there is no normative data available for its interpretation in Indian population.
- Conditions
- Small Bowel Disease, Motility Disorder, Irritable Bowel Syndrome
- Trial name
- NCT05004207
- Testing
- 99mTc Scintigraphy
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Anal Incontinence
Does the Negativation of the Glucose Hydrogen Breath Test Come Along With a Reduction of the Symptoms of Gaz Incontinence ?
The objectives of this work are: 1/to estimate the frequency of a positive glucose breath test in favour of a small intestinal bacterial overgrowth in a population of patients consulting for gaz incontinence by comparison to a…
- Trial name
- NCT01275560
- Testing
- Metronidazole, CArbosylane
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Asthma
The Asthma Bronchial Challenge Study
This is a randomised, controlled, cross-over study to determine the effect of indirect bronchial challenge testing upon volatile organic compounds (VOCs) in the exhaled breath of adults with well-controlled, mild-to-moderate…
- Trial name
- ABC (NCT03575663)
- Testing
- Indirect bronchial challenge
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Glucose Intolerance, Insulin Resistance
Diagnosis of Insulin Resistance: 13C-Glucose Breath Test Vs HOMA Index.
The prevalence of type 2 diabetes is rising in the population for many years. It is now recognized that a period of glucose intolerance precedes the clinical symptoms appearance.
- Conditions
- Glucose Intolerance, Insulin Resistance, Diabetes Mellitus, Type 2
- Trial name
- NCT00264940
- Sponsor
- Tel-Aviv Sourasky Medical Center
Bacterial Infection Due to Helicobacter Pylori (H. Pylori), Eradication Therapy of Helicobacter Pylori
Reinfection After Eradication of Helicobacter Pylori Infection
Helicobacter pylori is closely related with gastritis, peptic ulcer, gastric cancer and gastric MALT lymphoma, and it may participate in a variety of parenteral diseases.
- Conditions
- Bacterial Infection Due to Helicobacter Pylori (H. Pylori), Eradication Therapy of Helicobacter Pylori, Detection of Helicobacter Pylori
- Trial name
- RAEHPI (NCT02674802)
- Where
- China
- Volunteers
- 3,500 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Gastroesophageal Reflux, Regurgitation
A Study of Breath Testing for Small Intestinal Bacterial Overgrowth
Researchers hope to determine how often small intestinal bacterial overgrowth occurs after taking proton pump inhibitors.
- Conditions
- Gastroesophageal Reflux, Regurgitation, Heartburn
- Trial name
- NCT05976165
- Testing
- Breath Testing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Pulmonary TB, Diagnoses Diseases
Performance Evaluation of TB Breath- and Cough-testing Platforms
This will be a prospective, multicentre study conducted to evaluate the diagnostic accuracy of two TB breath-based technologies independently of the manufacturers.
- Trial name
- NCT03025516
- Testing
- Rapid Biosensor Systems (RBS) TB Breathalyser, eNose AeonoseTM
- Where
- South Africa
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Find