Clinical trials: Breathing-Related Sleep Disorder
Obstructive Sleep Apnea, Insulin Resistance
Exploring the Role of Adipocyte Fatty Acid Binding Protein in the Association of Obstructive Sleep Apnea and Metabolic Dysfunction
Adipocyte fatty acid binding protein (A-FABP) is a member of the FABP super family, is abundant in adipocytes and macrophages. Regulatory functions of A-FABP in lipid and glucose metabolism have been described, and it is…
- Conditions
- Obstructive Sleep Apnea, Insulin Resistance, Metabolic Syndrome, Inflammation
- Trial name
- NCT01173432
- Testing
- continuous positive airway pressure
- Where
- Hong Kong
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Obstructive Sleep Apnea, Obesity
Obesity and Obstructive Sleep Apnea (OSA) in Children
The goal of this research is to study the prevalence of sleep disordered breathing and associated morbidity in obese children and to examine the role of diet and physical activity in the treatment of sleep-disordered breathing in…
- Trial name
- NCT01135147
- Testing
- Diet, Surgery
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Sleep Apnea, Insomnia
Adult Sleep Health in the Rural Appalachia and Mississippi Delta Region and Its Relationships With Cardiometabolic Health Disparities.
Rural communities in the southern U.S. suffer a disproportionate burden of morbidity and mortality from cardiometabolic disease, with traditional risk factors explaining only a modest proportion of the excess burden of disease.
- Conditions
- Sleep Apnea, Insomnia, Sleep Deprivation, Sleep Disorders, Circadian Rhythm
- Trial name
- NCT06336525
- Where
- United States
- Volunteers
- 3,680 people
- Sponsor
- Brigham and Women's Hospital
Breathing, Sleep Disorder
Effect of Breathing Exercise on Certain Physiological Parameters, Sleep Quality and Vitality in Elderly
Objective: To determine the effect of breathing exercises on certain physiological parameters, sleep quality and vitality in the elderly.
- Trial name
- NCT04469972
- Testing
- Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Aysun Erdal
Sleep Apnea, Spinal Cord Injuries
Untreated Sleep Apnea as an Aggravating Factor for Other Secondary Medical Conditions After Spinal Cord Injury
This cross-sectional prospective study will assess the potential association of more severe sleep apnea after spinal cord injury with more intense neuropathic pain, more severe spasticity, and more significant cardiovascular…
- Conditions
- Sleep Apnea, Spinal Cord Injuries, Spasticity, Muscle, Neuropathic Pain
- Trial name
- NCT05687097
- Testing
- Home-based sleep screening test or hospital-unattended sleep screening test, Cardiovascular beat-to-beat monitoring, ECG monitoring
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Asthma, Obstructive Sleep Apnea
Asthma and Obstructive Sleep Apnea (OSA)
Obstructive sleep apnea (OSA) is a common but under-diagnosed form of sleep disordered breathing (SDB). Asthma is a common disease with rising prevalence, which continues to pose significant morbidity and costs.
- Trial name
- NCT01026298
- Testing
- FDA-Approved Treatment
- Where
- United States
- Volunteers
- 744 people
- Sponsor
- University of Wisconsin, Madison
Age-related Macular Degeneration, Age-related Maculopathy
GARM II: A Study on the Genetics of Age-related Maculopathy
The original study (GARM I) has been conducted for more than 18 years at the University of Pittsburgh Medical Center (UPMC). GARM II is a nationwide research study about age-related macular degeneration in the next generation of…
- Trial name
- NCT01115387
- Testing
- Observational-1, Observational-2
- Where
- 2 sites in United States
- Volunteers
- 603 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Sleep Apnea, Obstructive
Is Change in Mouth Opening Related to Change in Quality of Life in Children With Type 1 Obstructive Sleep Apnea After Adenotonsillectomy?
The goal of this clinical trial is to learn if changes in quality of life are linked to changes in mouth opening after adenotonsillectomy in a group of children who were diagnosed with Type 1 Obstructive Sleep Apnea (OSA1).
- Trial name
- JawChild (NCT06973928)
- Testing
- Measures of jaw activity using the Jawac
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Groupe Adène
Bruxism, Sleep, Obstructive Sleep Apnea
Association Between Obstructive Sleep Apnea and Bruxism
The objective of this retrospective observational study will be to investigate the between the Obstructive Sleep Apnea Syndrome (OSAS) and Sleep Bruxism (SB), in individuals diagnosed through polysomnography (PSG).
- Trial name
- NCT03810248
- Where
- Brazil
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Osa Syndrome
Psychological Aspects in OSA
The research project consists of an observational study. Obstructive Sleep Apnea (OSA) is a condition characterized by recurrent episodes of upper airway collapse during sleep, leading to decreased blood oxygen levels and…
- Trial name
- PSICOSA (NCT06292325)
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Italy
- Volunteers
- 246 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Interface, Mask, Continuous Positive Airway Pressure (CPAP)
CPAP and NIV Interfaces : Side-effects in Home Care Patients
Home ventilation techniques consist mainly of two techniques, Continuous Positive Airway Pressure or CPAP and Non Invasive Ventilation or NIV. Whether for CPAP or NIV, pressures are delivered to the patient via an interface.
- Conditions
- Interface, Mask, Continuous Positive Airway Pressure (CPAP), Non Invasive Ventilation (NIV), Hyperventilation Anxiety
- Trial name
- InterfaceVent (NCT03013283)
- Testing
- self questionnaire
- Where
- 2 sites in France
- Volunteers
- 6,000 people
- Sponsor
- University Hospital, Montpellier
Travel, Sleep Related Disorder
Travelling in Patients With Sleep Related Breathing Disorders
One questionnaire has been configured to ask therapy naive and treated patients about their travel activities. Travel activities include private and professional traveling. Another questionnaire collects medical information.
- Trial name
- NCT02636478
- Testing
- questionnaire for travel habits
- Volunteers
- 345 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Sleep Apnea, Obstructive, Pregnancy Related
Efficacy of Oral Appliances on Obstructive Sleep Apnea During Pregnancy
Issue: The prevalence and severity of sleep-disordered breathing increases during pregnancy due to weight gain, physiological and hormonal changes.
- Trial name
- OSApod (NCT03138291)
- Testing
- Somnodent
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Obstructive Sleep Apnea, Sleep-disordered Breathing
Effects of Exercise on Obstructive Sleep Apnea Severity in Elderly
Obstructive sleep apnea syndrome (OSAS) is defined as a total cessation of upper airway flow for at least 10 seconds. OSAS is considered under diagnosed and it is assessed by a full-night sleep polysomnography.
- Conditions
- Obstructive Sleep Apnea, Sleep-disordered Breathing, Sleep Disorder; Breathing-Related
- Trial name
- NCT04120428
- Testing
- Aquatic exercise training program
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Federal University of Paraíba
High Altitude Pulmonary Hypertension, Sleep
Nocturnal Oxygenation and Sleep-related Breathing Disorders During the First Night of a Stay at 2500m of High Altitude in Patients With Precapillary Pulmonary Hypertension
The impact of hypoxia at 2500m of high altitude on sleep in patients with precapillary pulmonary hypertension
- Trial name
- NCT05089487
- Testing
- Nocturnal rest (sleep study)
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University of Zurich
Respiratory Patients
Clinical Validation of New Breathing Sensors in Patients With Respiratory Insufficiency
The NXT_SLEEP study, bringing together industry partners, research groups and (home) care providers, tackles will develop a next generation sleep-monitoring platform that consists of less obtrusive sensors, and that delivers…
- Trial name
- NXT_SLEEP (NCT01904344)
- Testing
- Sensor testing and validation
- Where
- Belgium
- Volunteers
- 28 people
- Sponsor
- University Hospital, Antwerp
Sleep Apnea, Age
Determinants of Age Related Breathing Instability During Non-Rapid-Eye-Movement (NREM) Sleep
The purpose for this research protocol was to examine the role of breathing control mechanisms that determine the development of sleep-disordered breathing in the elderly.
- Trial name
- NCT00732199
- Testing
- 1) hyperventilation via noninvasive positive pressure ventilation 2) multiple trials of episodic hypoxia
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Sleep Bruxism, Sleep Disorder
Relationship Between Selected Parameters and Bruxism
Bruxism is a common phenomenon. It is estimated that its prevalence in the adult population is 8-31%. Bruxism occurring during sleep is the activity of the masticatory muscles that appear during sleep, which can be rhythmic or…
- Conditions
- Sleep Bruxism, Sleep Disorder, Psychosomatic Disorder, Pain
- Trial name
- WMU1/2019 (NCT04214561)
- Testing
- Polysomnography
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Bruxism, Bruxism, Sleep-Related
Diaphragmatic Breathing for Sleep Bruxism in Adults: A Randomized Controlled Trial
The goal of this clinical trial is to learn if a diaphragmatic breathing program can reduce sleep bruxism in adults. The main questions it aims to answer are: Can diaphragmatic breathing lower the frequency of teeth grinding…
- Trial name
- DB4SB (NCT07181642)
- Testing
- Diaphragmatic Breathing Program, Neutral Music Listening
- Where
- Tunisia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Sleep Disorder, Body Fat Distribution
Relationship Between Normal-weight Central Obesity and Obstructive Sleep Apnea
Comparison of the prevalence of obstructive sleep apnea (OSA), measured by polysomnography in normal weight patients with central obesity by body mass index (BMI) and waist hip ratio (WHR), with normal weight patients without…
- Trial name
- NCT04061226
- Testing
- Overnight polysomnography
- Where
- Czechia
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic