Clinical trials: Broccoli Sprout
Breast Cancer, Precancerous Condition
Broccoli Sprout Extract in Treating Women Who Have Had a Mammogram and Breast Biopsy
RATIONALE: Broccoli sprout extract supplements may slow the growth of tumor cells or abnormal cells and may be an effective treatment for ductal carcinoma in situ and/or atypical ductal hyperplasia.
- Trial name
- NCT00843167
- Testing
- broccoli sprout extract
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- OHSU Knight Cancer Institute
Environmental Carcinogenesis
Broccoli Sprout Dose Response: Bioavailability and Effects of Air Pollutants
This study will examine the extent to which lower doses of a broccoli-derived beverage enhance the detoxication of air pollutants excreted in urine as compared to an maximal dose shown to be effective previously.
- Trial name
- NCT02656420
- Testing
- Broccoli Sprout-derived Beverage
- Where
- China
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Adenocarcinoma of the Prostate, Recurrent Prostate Cancer
Sulforaphane in Treating Patients With Recurrent Prostate Cancer
This phase II trial studies how well sulforaphane works in treating patients with recurrent prostate cancer. Sulforaphane may prevent or slow the growth of certain cancers.
- Trial name
- NCT01228084
- Testing
- Sulforaphane, Laboratory biomarker analysis, Pharmacological study
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- OHSU Knight Cancer Institute
Asthma, COPD
The Effects of Broccoli Sprout Extract on Obstructive Lung Disease
The purpose of this study is to examine whether broccoli sprout extract can effect lung function measurements in individuals with asthma and COPD.
- Trial name
- NCT00994604
- Testing
- broccoli sprout extract
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
COPD
Broccoli Sprout Extracts Trial to See if NRF2 is Enhanced by Sulforaphane Treatment in Patients With COPD
Evidence from investigators' group has shown that chronic obstructive pulmonary disease (COPD) patients have impairment of antioxidant defenses which are caused by a defect in activity of Nrf2.
- Trial name
- BEST (NCT01335971)
- Testing
- Sulforaphane 25, Sulforaphane 150
- Where
- 3 sites in United States
- Volunteers
- 89 people
- Sponsor
- Johns Hopkins University
Histone Deacetylase (HDAC) Activity
Dietary Histone Deacetylase Inhibitors (HDAC)
This pilot, three-week study will help scientists understand more about how the foods people eat can modify histone deacetylases, enzymes the body produces naturally.
- Trial name
- NCT01543074
- Testing
- Garlic oil, BSE
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Environmental Carcinogenesis
Broccoli Sprout Intervention in Qidong, P.R. China
This study is a 12 week placebo-controlled Phase II broccoli sprout intervention to be conducted in Qidong, P.R. China. One thousand two hundred people from the farming townships will be screened and three hundred eligible…
- Trial name
- NCT01437501
- Testing
- Broccoli Sprout Extract Beverage
- Where
- China
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Allergic Airway Disease
Broccoli Sprout Extract Effects on Allergic Inflammation in the Nose
Allergic airway disease is a term used to describe conditions such as allergic rhinitis and asthma. Among other causative agents, air pollutants and diesel exhaust in particular, have been shown to create and also worsen existing…
- Trial name
- NCT00882115
- Testing
- Broccoli sprout extract (BSE)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Rhinitis,Allergic
Effects of Broccoli Sprout Extract on Allergy Rhinitis
Allergic rhinitis is a common illness suffered among US Veterans. There are medications that help relieve allergy symptoms, including nasal steroid sprays and antihistamines.
- Trial name
- NCT02885025
- Testing
- Broccoli Sprout Extract, fluticasone nasal, normal saline nasal spray
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Autism
Sulforaphane-rich Broccoli Sprout Extract for Autism
The primary objectives of this study are to answer whether there is evidence of measurable effects on social responsiveness (primary outcome) and other behavioral symptoms after treatment of autistic male adolescents and adults…
- Trial name
- NCT01474993
- Testing
- Sulforaphane-rich Broccoli Sprout Extract
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Andrew Zimmerman
Recurrent Bladder Cancer, Stage 0 Bladder Cancer
Broccoli Sprout Extract in Treating Patients With Transitional Cell Bladder Cancer Undergoing Surgery
Rationale: Broccoli sprout extract contains ingredients that may prevent or slow the growth of certain cancers. Purpose: This pilot study is studying the side effects of broccoli sprout extract in treating patients with…
- Conditions
- Recurrent Bladder Cancer, Stage 0 Bladder Cancer, Stage I Bladder Cancer, Stage II Bladder Cancer
- Trial name
- NCT01108003
- Testing
- broccoli sprout extract, laboratory biomarker analysis, Mango Juice
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Roswell Park Cancer Institute
Breast Cancer
Study to Evaluate the Effect of Sulforaphane in Broccoli Sprout Extract on Breast Tissue
The purpose of this research is to examine the effect of a broccoli sprout preparation on specific factors in breast tissue that are related to breast cancer risk and to assess whether sulforaphane a key component of broccoli…
- Trial name
- NCT00982319
- Testing
- Broccoli sprout extract, Mango juice
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Cigarette Smoking-Related Carcinoma, Tobacco-Related Carcinoma
Broccoli Sprout/Broccoli Seed Extract Supplement in Decreasing Toxicity in Heavy Smokers
This randomized early phase I trial studies how well broccoli sprout/broccoli seed extract supplement works in decreasing toxicity in heavy smokers.
- Trial name
- NCT03402230
- Testing
- Broccoli Sprout/Broccoli Seed Extract Supplement, Laboratory Biomarker Analysis, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)