Clinical trials: Bronchial Asthma
Asthma in Children
Impact of Modified Specific Carbohydrate Diet on Bronchial Asthma Control in Children
The aim of this study will explore if the specific carbohydrate diet has an effect on asthma control in children and if it will affect the frequency, severity, and duration of asthma and thus provide it as a potential…
- Trial name
- NCT05728385
- Testing
- Modified Specific carbohydrate diet for 3 months
- Volunteers
- 60 people
- Sponsor
- Tanta University
Eosinophilic Asthma
Study to Evaluate the Efficacy and Safety of Reslizumab Treatment in Patients With Moderate to Severe Asthma
The primary objective of the study is to characterize the efficacy of reslizumab treatment, at a dosage of 3.0 milligrams per kilogram (mg/kg) every 4 weeks for a total of 4 doses, in improving pulmonary function in relation to…
- Trial name
- NCT01508936
- Testing
- Reslizumab
- Where
- 66 sites in United States
- Volunteers
- 511 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Asthma
Pragmatic Clinical Trial to Assess the Effectiveness of Pharmaceutical Intervention in Patients With Uncontrolled Asthma
The aim of this study is to evaluate the effectiveness of pharmaceutical intervention in controlling asthma in patients diagnosed with uncontrolled asthma.
- Trial name
- NCT06227793
- Testing
- pharmaceutical intervention
- Where
- Brazil
- Volunteers
- 76 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Healthy, Asthma
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 1021958 in Otherwise Healthy Controlled Asthmatic Subjects
To investigate safety, tolerability, pharmacokinetics including posology, and pharmacodynamics of multiple rising doses of BI 1021958 in otherwise healthy mild asthmatic subjects
- Trial name
- NCT01629849
- Testing
- BI 1021958 bid, BI 1021958 qd
- Where
- Germany
- Volunteers
- 84 people
- Sponsor
- Boehringer Ingelheim
Asthma
A Study To Assess The Safety And Effectiveness Of Medrol® In Acute Asthma In Indian Patients
The present study is designed to collect data on real world experience on use of Medrol in acute asthma in Indian patients.
- Trial name
- NCT00971893
- Testing
- Oral Methylprednisolone Tablets
- Sponsor
- Pfizer
Asthma
Long-term Safety and Efficacy Evaluation of Subcutaneous Amlitelimab in Adult Participants With Moderate-to-severe Asthma Who Completed Treatment Period of Previous Amlitelimab Asthma Clinical Study
This is a study of amlitelimab for the treatment of participants with moderate-to-severe asthma. The study will have a double-blind treatment period until Week 24 for each participant and an open-label treatment period where each…
- Trial name
- RIVER-ASTHMA (NCT06033833)
- Testing
- Amlitelimab
- Where
- 68 sites in United States, Argentina and 12 more
- Volunteers
- 335 people
- Sponsor
- Sanofi
Asthma
A Comparison of Diagnostic Testing Modalities in the Assessment of Asthma
This study aims to assess the concordance of international asthma guidelines in the diagnosis of asthma and explore the presence of airways disease using additional non-guideline physiologic criteria, such as IOS (impulse…
- Trial name
- MODELS (NCT06286085)
- Testing
- Lung function tests
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Obesity, Asthma
The Effect of Obesity on Lung Functioning
This research study is looking at the effects of weight loss, due to surgery or structured weight-loss program on lung function, inflammation in your body and lungs, asthma and asthma symptoms.
- Trial name
- NCT00284895
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Jewish Health
Asthma, Asthma Attack
Optimisation of ASthma In Those With Uncontrolled Symptoms (OASIS)
A digital tool, called ReferID has been developed to facilitate the review of asthma patients. It aims to assist in the identification of patients with uncontrolled and/or severe asthma and to ensure a timely referral to…
- Conditions
- Asthma, Asthma Attack, Asthma Persistent, Covid19
- Trial name
- OASIS (NCT04941001)
- Testing
- ReferID
- Where
- United Kingdom
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Hyperventilation, Larynx
Vocal Cord Responses During Hyperventilation in Normal Individuals and in Mild and Severe Asthmatics.
The Investigators aim to: 1. Study the effect of hyperventilation on the development of paradoxical vocal cord movement (PVCM) in healthy individuals and in patients with mild and severe asthma, 2.
- Conditions
- Hyperventilation, Larynx, Asthma
- Trial name
- NCT05565430
- Testing
- Acute Hyperventilation, Chronic hyperventilation, Effects of anticholinergic medication
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Monash Medical Centre
COPD, Asthma
Health Effects of Secondhand Smoke Exposure in Outdoor Smoking Areas in Patients With COPD and Asthma ( TackSHSWP5 )
Within the TackSHS project (H2020 project grant agreement No 681040), we will conduct a clinical research study, aiming at: i) to measure respiratory health effects when exposed to secondhand smoke (SHS) in patients with asthma…
- Conditions
- COPD, Asthma, Second Hand Tobacco Smoke
- Trial name
- TackSHSWP5 (NCT03074734)
- Testing
- Exposure to secondhand tobacco smoke
- Volunteers
- 60 people
- Sponsor
- Institut Català d'Oncologia
Asthma
A Multifaceted Prompting Intervention for Urban Children With Asthma
The overall goal of this project is to evaluate whether a multifaceted prompting intervention, administered in the urban primary care office setting, reduces morbidity among urban children with asthma.
- Trial name
- PAIR-UP (NCT01105754)
- Testing
- Multifaceted Prompting Intervention MPI
- Where
- United States
- Volunteers
- 638 people
- Sponsor
- University of Rochester
Asthma
Bioequivalency Study of Montelukast Chewable 5 mg Tablets Under Fasted Conditions
The objective of this study was to prove the bioequivalence of Montelukast Chewable Tablet under fasted conditions.
- Trial name
- NCT01659905
- Testing
- Montelukast, Singulair
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Asthma, Chronic Obstructive Pulmonary Disease COPD
A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD7594 Inhaled Formulation in Healthy Japanese Men
This is a randomized, single-blind, placebo-controlled, sequential-group study to assess the safety and tolerability as well as how the drug (AZD7594) affects the body (pharmacodynamics [PD]) and how the body affects the drug…
- Trial name
- NCT02645253
- Testing
- AZD7594 inhalation powder (200 μg), AZD7594 inhalation powder (400 μg), AZD7594 pressurized inhalation suspension (200 μg)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Asthma
Clinical Study to Evaluate the Efficacy of VR506 Using a New Inhaler for the Treatment of Asthma
The purpose of the study is to evaluate the clinical efficacy of three doses of VR506 delivered via a new dry powder inhaler for the treatment of asthma.
- Trial name
- NCT01472757
- Testing
- VR506
- Where
- 82 sites in United States, Philippines and 3 more
- Volunteers
- 374 people
- Sponsor
- Vectura Limited
Late-Onset Asthma
Asthma Severity in Women: The Influence of Training and Menopause
Introduction: Late-onset asthma in women is characterized by poor disease control and reduced quality of life despite intensive treatment with inhaled steroid and beta2-agonist.
- Trial name
- ATOM (NCT03747211)
- Testing
- Aerobic exercise
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Effect of Breastfeeding on Maternal and Child Health Outcomes
Promotion of Breastfeeding Intervention Trial
The overall goal of the PROBIT study is to investigate the influence of a randomized breastfeeding promotion intervention designed to increase the duration and exclusivity of breastfeeding ("the breastfeeding promotion…
- Trial name
- PROBIT (NCT01561612)
- Testing
- Breastfeeding promotion and support
- Where
- Belarus
- Volunteers
- 17,046 people
- Sponsor
- Harvard Pilgrim Health Care
Asthma
SAS115359: A 6-month Study to Assess the Safety and Benefit of Inhaled Fluticasone Propionate/Salmeterol Combination Compared With Inhaled Fluticasone Propionate in the Treatment of Adolescents and Adults (12 Years of Age and Older) With Asthma.
The purpose of this study is to assess whether the risk of serious asthma-related events (asthma-related hospitalizations, endotracheal intubations, and deaths) in adolescents and adults (12 years of age and older) taking inhaled…
- Trial name
- AUSTRI (NCT01475721)
- Testing
- ADVAIR 100/50mcg, ADVAIR 250/50mcg, ADVAIR 500/50mcg
- Where
- 808 sites in United States, Argentina and 31 more
- Volunteers
- 11,751 people
- Sponsor
- GlaxoSmithKline
Asthma
Evaluation of Triple Therapy Using Magnetic Resonance Imaging in Asthma
The purpose of this study is to evaluate the effectiveness of treatment with triple therapy an inhaler that contains three types of asthma medications, on participants with poorly controlled asthma.
- Trial name
- ETHA (NCT04651777)
- Testing
- FF/UMEC/VI
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Dr. Grace Parraga
Impact of Health Information Exchange on Patient Care, (Focus on Diabetes, Asthma, Hypertension, CHF, COPD, CAD,
Evaluation of a Regional Electronic Health Information Exchange's Clinical Health Record
The Shared Health CHR™ (Clinical Health Record) offers point-of-care clinical reporting and decision support based primarily on patient claims data aggregated across various health care settings, and is one example of the types…
- Conditions
- Impact of Health Information Exchange on Patient Care, (Focus on Diabetes, Asthma, Hypertension, CHF, COPD, CAD,, Gastroenteritis, Seizures, and Bacterial Pneumonia)
- Trial name
- NCT00978744
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital