Clinical trials: Bronchiolitis, Viral
Bronchiolitis; Chemical, Reflexology
The Effect of Reflexology in Patients With Viral Bronchiolitis
To test the influence of reflexology on bronchiolitis.
- Trial name
- NCT05799677
- Testing
- Reflexology
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hillel Yaffe Medical Center
Bronchiolitis, Viral
Efficacy of Magnesium Sulfate Bolus in Pediatric Patients With Bronchiolitis
The purpose of this study is to more rigorously evaluate the response to a single bolus of magnesium sulfate in a population of patients with moderate to severe bronchiolitis.
- Trial name
- NCT04740294
- Testing
- Magnesium Sulfate
- Where
- United States
- Sponsor
- University of Louisville
Respiratory Tract Infections, Bronchiolitis Obliterans
Steroids, Azithromycin, Montelukast, and Symbicort (SAMS) for Viral Respiratory Tract Infection Post Allotransplant
For many patients with blood cancers, stem cell transplantation from a family member or from an unrelated donor remains the only potentially curative option.
- Conditions
- Respiratory Tract Infections, Bronchiolitis Obliterans, Cryptogenic Organizing Pneumonia, Lung Diseases, Interstitial
- Trial name
- NCT01432080
- Testing
- Prednisone, Azithromycin, Montelukast
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Bronchiolitis
Peak Tidal Inspiratory Flow in Infants With Moderate to Severe Acute Viral Bronchiolitis
This aim of this study is to measure the peak tidal inspiratory flow (PTIF), using spirometry, in young infants with moderate to severe acute viral bronchiolitis (AVB).
- Trial name
- DEBIB (NCT03298217)
- Testing
- Measurement of the peak tidal inspiratory flow (PTIF)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Bronchopulmonary Dysplasia, Preterm Infant Development
PremaBiom: Metatranscriptomics of the Respiratory Microbiome to Predict the Occurrence of Bronchopulmonary Dysplasia in Preterm Infants
The goal of this clinical trial is to understand the impact of respiratory microbiome maturation in respiratory health of preterm infants under 32 gestational weeks.
- Conditions
- Bronchopulmonary Dysplasia, Preterm Infant Development, Asthma Childhood, Bronchiolitis
- Trial name
- PremaBiom (NCT07411261)
- Testing
- Nasal swab, blood sampling, Mother milk sampling
- Where
- 6 sites in France
- Volunteers
- 270 people
- Sponsor
- University Hospital, Caen
Viral Bronchiolitis
Hypertonic Saline to Reduce Hospital Admissions in Bronchiolitis
Inhaled 3% hypertonic saline (HS) administered every 2-8 hours to infants admitted to hospital with viral bronchiolitis has been shown to improve airway clearance and reduces length of stay.
- Trial name
- NCT00677729
- Testing
- solution contains 1 mg salbutamol plus 3% hypertonic saline, solution contains 1 mg salbutamol plus 0.9% saline
- Where
- 3 sites in Canada
- Volunteers
- 81 people
- Sponsor
- Queen's University
Hepatitis C, Liver
Study Investigating Immunological Effects of Treatment for Chronic Hepatitis C Patients.
Aim To evaluate the effects of peginterferon and ribavirin therapy on the immune response in chronic HCV genotype 1,2 or 3 patients before, during and after treatment.
- Conditions
- Hepatitis C, Liver, Immunology, Regulation
- Trial name
- CIRES (NCT00422838)
- Testing
- fine-needle aspiration biopsy
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Foundation for Liver Research
Hepatitis C, Hepatocellular Carcinoma
Efficacy of Sofosbuvir With Ribavirin Administered Pre-Transplant in Preventing Hepatitis C Virus (HCV) Recurrence Post-Transplant
The primary objective is to determine if the administration of a combination of sofosbuvir (SOF; GS-7977; PSI-7977) and ribavirin (RBV) to HCV-infected adults with hepatocellular carcinoma (HCC) meeting the MILAN criteria prior…
- Trial name
- NCT01559844
- Testing
- Sofosbuvir, Ribavirin
- Where
- 15 sites in United States, New Zealand and 1 more
- Volunteers
- 61 people
- Sponsor
- Gilead Sciences
Hepatitis B, HIV Infection
Adefovir Dipivoxil to Treat Hepatitis B in HIV-Infected Patients
This study will evaluate the safety and effectiveness of adding the experimental drug adefovir dipivoxil to lamivudine for treating hepatitis B virus (HBV) infection in HIV-infected patients with liver cirrhosis.
- Trial name
- NCT00013702
- Testing
- Adefovir
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HCV Infection
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ACH-0137171 in Participants With Chronic Hepatitis C Infection
The purpose of this study was to investigate the safety, tolerability, pharmacokinetics (PK), and antiviral activity of multiple doses of ACH-0137171 in participants with chronic hepatitis C virus (HCV) infection.
- Trial name
- NCT00401947
- Testing
- ACH-0137171
- Where
- 9 sites in United States, Germany and 1 more
- Volunteers
- 30 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Severe Bronchiolitis
Prone Position Effects on Work of Breathing and Intrinsic PEEP in Children With Severe Acute Viral Bronchiolitis
Acute viral bronchiolitis is the first cause of respiratory distress in infant. Airway inflammation increases the respiratory system resistances and dynamic hyperinflation. This leads to an increase in the work of breathing.
- Trial name
- BRONCHIO-DV (NCT02602678)
- Testing
- Supine then Prone position, Prone then supine position
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Hospices Civils de Lyon
Acute Viral Bronchiolitis
Efficacy of 3% Hypertonic Saline in Acute Viral Bronchiolitis
The purpose of this study is to determine whether nebulized hypertonic saline solution reduces the admission rate 48 hours after initial treatment in the emergency department, when compared to normal saline solution (control).
- Trial name
- GUERANDE (NCT01777347)
- Testing
- 3% Saline, 0.9% Normal Saline
- Where
- 21 sites in France
- Volunteers
- 778 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy
A Drug Interaction Study to Assess the Pharmacokinetics of Narlaprevir and Antiretroviral Drugs
The study purpose is to evaluate the potential for a pharmacokinetic drug-drug interaction, safety and tolerability when Narlaprevir, Ritonavir (used as a metabolic inhibitor) and Tenofovir disoproxil fumarate (part 1) and…
- Trial name
- NCT03537404
- Testing
- Narlaprevir, Ritonavir, Tenofovir Disoproxil Fumarate
- Where
- Russia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- R-Pharm
Bronchiolitis, Viral, Pneumonia, Viral
Pediatric Helmet CPAP Pilot Study
This a research study to find out whether giving Continuous Positive Airway Pressure (CPAP) through a Helmet is the same or better than giving CPAP through a Facemask, Nasal Mask, or Nasal Prongs.
- Conditions
- Bronchiolitis, Viral, Pneumonia, Viral, Pneumonia, Bacterial
- Trial name
- NCT04764929
- Testing
- Helmet CPAP
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Columbia University
Bronchiolitis, Viral, Home Nursing
Home Oxygen Treatment of Childhood Acute Bronchiolitis
Background: acute bronchiolitis (AB) is a common reason for hospitalization of infants in all population groups, and is usually due to respiratory syncytial virus (RSV) infection.
- Trial name
- NCT01618175
- Testing
- Home oxygen therapy
- Volunteers
- 85 people
- Sponsor
- Soroka University Medical Center
Bronchiolitis, Viral
Steroid Use in Non-RSV Bronchiolitis
The proposed study is a pilot randomized control trial to determine the efficacy of dexamethasone use in hospitalized children who are less than 2 years of age with non-respiratory syncytial virus (RSV) bronchiolitis admitted to…
- Trial name
- NCT04221087
- Testing
- Dexamethasone Oral
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Allison Williams
Hepatitis B, ESRD (End Stage Renal Disease)
Comparing Hepatitis B Vaccination Schedules in Patients on Hemodialysis
People with kidney failure who are on dialysis have a weaker immune response to the hepatitis B vaccine than healthy people. Even after vaccination, many dialysis patients do not develop enough protection against hepatitis B…
- Conditions
- Hepatitis B, ESRD (End Stage Renal Disease), Kidney Failure, Chronic
- Trial name
- 3v4-HEP-DOSE (NCT07784452)
- Testing
- Recombinant Hepatitis B Vaccine - 3-Dose Schedule, Recombinant Hepatitis B Vaccine - 4-Dose Schedule
- Where
- Pakistan
- Volunteers
- 104 people
- Sponsor
- Jinnah Hospital
Acute Viral Bronchiolitis
NAVA in Infants With Acute Viral Bronchiolitis: A Feasibility Study
This exploratory intervention feasibility study aims to evaluate the use of a novel mode of ventilation known as Neurally adjusted ventilatory assist (NAVA) in infants with acute viral bronchiolitis. The main aims are: 1.
- Trial name
- NCT05899894
- Testing
- Neurally Adjusted Ventilatory Assist
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Bronchiolitis
The Effectiveness of AAD and IPV to Treat Hospitalized Infants (<2years) With Acute Viral Bronchiolitis.
The purpose of this study is to investigate the effectiveness of two airway clearance techniques; Intrapulmonary Percussive Ventilation and Assisted Autogenic Drainage in hospitalized infants under the age of 2 with acute viral…
- Trial name
- NCT02126748
- Testing
- inhalation 4ml hypertonic saline 3% 3x/day, Intrapulmonary Percussive Ventilation, Assisted Autogenic Drainage
- Where
- Belgium
- Volunteers
- 103 people
- Sponsor
- Vrije Universiteit Brussel
Bronchiolitis, Viral
Single Injection of Dexamethasone for Acute Bronchiolitis in Young Children
The purpose of this study was to determine whether a single intramuscular injection of dexamethasone decreased the duration of symptoms of acute bronchiolitis in young children.
- Trial name
- NCT00122785
- Testing
- dexamethasone
- Where
- Thailand
- Volunteers
- 170 people
- Sponsor
- Khon Kaen University