Clinical trials: Bronchopulmonary Infection
Allergic Bronchopulmonary Aspergillosis
Phase 1 Three Part SAD, MAD & Cross-Over Study of ZP-059 in Healthy and Asthmatic Subjects
The primary safety objectives were: Part 1: To determine the safety and tolerability of single doses of ZP-059 in healthy subjects Part 2: To determine the safety and tolerability of multiple doses of ZP-059 in subjects with mild…
- Trial name
- NCT04229303
- Testing
- Voriconazole inhaled, oral voriconazole
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Zambon SpA
Aspergillosis, Candidemia
A Study To Assess The Anidulafungin And Voriconazole Concentration In Lung Following Intravenous Administration In Healthy Subjects
The purpose of this study is to provide anidulafungin and voriconazole to healthy subjects to determine the drug concentration in the lung.
- Trial name
- NCT00940017
- Testing
- anidulafungin and voriconazole
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Chronic Obstructive Pulmonary Disease, Asthma
Clinical and Immunological Efficiency of Bacterial Vaccines at Adult Patients With Bronchopulmonary Pathology
Goal: to to examine the formation of postvaccination immunity and evaluate the therapeutic effect of bacterial vaccines in patients with inflammation diseases of bronchopulmonary system.
- Conditions
- Chronic Obstructive Pulmonary Disease, Asthma, Pneumococcal Infections
- Trial name
- NCT02787863
- Testing
- Prevenar-13, Pneumo-23
- Where
- 2 sites in Russia
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Mikhael Petrovich Kostinov
Bronchiectasis Adult, Mediastinal Lymphadenopathy
Lidocaine Administration During Flexible Bronchoscopy and Endobronchial Ultrasound
The purpose of this study is to assess if there is decrease in cough during flexible bronchoscopy and endobronchial ultrasound when different modes of lidocaine administration are used.
- Conditions
- Bronchiectasis Adult, Mediastinal Lymphadenopathy, Pneumonia, Chest--Diseases
- Trial name
- NCT03829618
- Testing
- Topical lidocaine, Nebuliser solution, Nebuliser Suspension
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Cystic Fibrosis
Safety, Tolerability, Pharmacokinetics, and Preliminary Pharmacodynamics of QBW251 in Healthy Subjects and Cystic Fibrosis Patients
This study is designed to assess the safety, tolerability, pharmacokinetics and preliminary pharmacodynamics (proof of concept) of QBW251 in healthy subjects and cystic fibrosis patients following single and multiple doses.
- Trial name
- NCT02190604
- Testing
- QBW251
- Where
- 23 sites in United States, Belgium and 5 more
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals