Clinical trials: Bronchoscopy；
Airway Disease
Treatment of Central Airway Stenoses Using Computer-Assisted Customized 3d Stents TATUM
Airway stenting is usually efficient to treat central airway obstruction but can lead to severe and potentially lethal complications (stent migration, obstructive granuloma, perforation, and hemoptysis).
- Trial name
- TATUM (NCT04848025)
- Testing
- Custom-designed tracheobronchial prostheses
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Lung Disease
Comparison of Propofol/Alfentanil With Propofol/Ketamine
A prospective, randomized, patient-blinded comparison of the safety and efficacy of conscious sedation by propofol/alfentanil with propofol/ketamine in patients undergoing flexible fiberoptic bronchoscopy.
- Trial name
- KET-001 (NCT02000206)
- Testing
- Propofol, Ketamine, Alfentanil
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rabin Medical Center
Tomography, Optical Coherence, Bronchoscopy
Measure Airway Compliance by Endobronchial Optical Coherence Tomography
Optical Coherence Tomography （OCT）is a novel, non-invasive, high resolution special optical imaging techniques. In airway, Measure airway area and airway wall thickness is the most usage of Endobronchial Optical Coherence…
- Conditions
- Tomography, Optical Coherence, Bronchoscopy, Respiratory Disease, Airway Remodeling
- Trial name
- NCT05692362
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Solitary Pulmonary Nodule, Lung Cancer
Bronchoscopic Approach to the Peripheral Lung Nodule - An Alternative Approach
Patients presenting with solitary or multiple lung nodules often require tissue confirmation in order to guide further management and determine if the lesion is benign or malignant.
- Trial name
- NCT00925210
- Testing
- Sequential pEBUS - ENB
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Pain
Safety and Efficacy of Intravenous (IV) Dexmedetomidine During Flexible Bronchoscopy and Endobronchial Ultrasound
To achieve safe,consistent, continuous sedation using Dexmedetomidine in advaced bronchoscopy procedures that may reduce the need for rapid pain sedative infusion.
- Trial name
- NCT00691886
- Testing
- dexmedetomidine hydrochloride
- Where
- United States
- Sponsor
- Lahey Clinic
Thoracic Surgery With One-lung Ventilation
Ultrasound vs. Auscultation and Fiberoptic Bronchoscopy for Double-Lumen Tube Placement
One-lung ventilation is frequently required in thoracic surgery and is most commonly achieved using double-lumen endobronchial tubes (DLTs).
- Trial name
- NCT07465510
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir City Hospital
Pulmonary Infection, Pulmonary Nodule
Remimazolam for Bronchoscopy in High-Risk Patients
Bronchoscopy is currently widely used for the diagnosis and treatment of various respiratory diseases. However, the operation of bronchoscopy is irritating, causes a strong stress response, and shares the airway with the patient…
- Conditions
- Pulmonary Infection, Pulmonary Nodule, Phthisis, Endotracheal Tumour
- Trial name
- NCT07395596
- Testing
- propofol and alfentanil, remimazolam combined with propofol and alfentanil
- Where
- 2 sites in China
- Volunteers
- 360 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Asthma, Healthy
Factors Involved in Asthma and Airway Inflammation
Asthma is the third leading cause of preventable admissions to the hospital in the United States. Deaths and diseases associated with asthma increase every year. Asthma is a disorder of airway inflammation.
- Trial name
- NCT00001887
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Bronchoscopy
Role of Bronchoscopy in Bronchiectasis
Role of bronchoscopy in diagnosis of bronchiectasis in to different types
- Trial name
- NCT04208607
- Testing
- Bronchoscopy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Nasotracheal Intubation
Nasotracheal Intubation in Children for Outpatient Dental Surgery
The aim of study was to compare the hemodynamic responses and adverse events associated with nasotracheal intubation (NTI) using a fiberoptic bronchoscope (FOB) and a direct laryngoscope (DLS) in children undergoing general…
- Trial name
- NCT02993692
- Testing
- Direct laryngoscopy and fiberoptic bronchoscopy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Inonu University
Lung Disorder
Effects of Different Ventilatory Strategy on Intraoperative Atelectasis During Bronchoscopy Under General Anesthesia.
This trial compares two different types of ventilation for the prevention of partial or complete collapsed lung (atelectasis) in patients undergoing interventional pulmonology procedures under general anesthesia.
- Trial name
- NCT05720845
- Testing
- VESPA, conventional mechanical ventilation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Bronchoscopy, Learning Curves and Outcomes of Simulation-based Training
Randomized Controlled Trial of Multi-Patient CT-Derived Digital Twin Anatomical Variability Training to Shorten the Clinical Learning Curve for Bronchoscopy
This study aims to determine whether multi-patient CT-derived digital twin anatomical variability training can shorten the early clinical learning curve of novice bronchoscopists compared with conventional anatomically uniform…
- Conditions
- Bronchoscopy, Learning Curves and Outcomes of Simulation-based Training, Learning Curve
- Trial name
- NCT07718451
- Testing
- Multi-patient CT-derived digital twin anatomical variability training, Anatomically uniform standard-model bronchoscopy simulation training
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Gang Hou
Lung Cancer
Feasibility of Targeted Bronchial Washing for Molecular Testing by Next Generation Sequencing in Early-stage Lung Cancer
This is a single center, clinical trial evaluating the relevance of intratumoral washing for detection of generic alteration with Next Generation Sequencing.
- Trial name
- NCT06301295
- Testing
- Ultarthin bronchoscopy with intratumoral washing
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Pusan National University Hospital
Asthma
A Methodology Study To Look At Genes In Lung Cells And Tissue From Asthmatic Patients
The primary goal of this study is to identify a gene or panel of genes which are differentially expressed in lung cells and tissue from asthmatic patients following administration of Ipratropium bromide and eiTher nebulised…
- Trial name
- NCT00331292
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- GlaxoSmithKline
Lung Cancer
ENB-guided Ablation Therapy Combined With VATS in the Treatment of MPLC
The study is designed as a prospective trial whose purpose is to evaluate the effectiveness and safety of ENB-guided ablation therapy combined with VATS in the treatment of multiple primary lung cancers (MPLC).
- Trial name
- NCT04730453
- Testing
- ENB-guided ablation therapy combined with VATS
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Chest Hospital
Lung Cancer
ENB Guided RFA for Early-stage Peripheral Lung Cancer
The objective of the study was to evaluate the efficacy and safety of electromagnetic navigation bronchoscopy (ENB) guided radiofrequency ablation (RFA) for the treatment of early-stage peripheral lung cancer.
- Trial name
- NCT03009630
- Testing
- RFA, ENB
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Chest Hospital
Peripheral Pulmonary Lesions (PPLs)
Advanced Robotic Techniques and Rapid Onsite Evaluation for Minimally Invasive Diagnosis and Next-Generation Sequencing.
ARTEMIS is a multicenter randomized controlled trial. The goal is to understand whether rapid onsite evaluation during robotic assisted bronchoscopy improves the diagnostic performance of the procedure or not.
- Trial name
- ARTEMIS (NCT07685977)
- Testing
- Rapid onsite evaluation
- Where
- 8 sites in United States
- Volunteers
- 400 people
- Sponsor
- Vanderbilt University Medical Center
Satisfaction, Personal
3D Printing in Airway Anatomy and Bronchoscopy Education
The main purpose of this study is to use 3D printing technology to make a human anatomical bronchial tree model, which is applied in medical education for medical students and students of the department of respiratory therapy.
- Trial name
- NCT05410236
- Testing
- 3D bronchial tree model
- Where
- Taiwan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University
Lung Diseases, Total Intravenous Anesthesia
Comparison of iGel and THRIVE on Bronchoscopic Interventions
THRIVE and iGEL were applied for maintain oxygenation in bronchoscopic interventions which could not performed with an endotracheal tube.
- Conditions
- Lung Diseases, Total Intravenous Anesthesia, Tracheal Diseases
- Trial name
- NCT05046223
- Testing
- The responses to bronchoscopic insertion for bronchoscopic interventions such asTBNA, Cryotherapy, etc., postoperative recovery
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- National Taiwan University Hospital
Pediatric Rigid Bronchoscopy
Remifentanil Use in Pediatric Rigid Bronchoscopy
Purpose: In this study we wanted to compare bolus propofol and ketamine as an adjuvant to remifentanil-based total intravenous anesthesia for pediatric rigid bronchoscopy.
- Trial name
- NCT01947114
- Testing
- Propofol, Ketamine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University