Clinical trials: Bulging
Pain, Acute, Pain, Chronic
Evaluation of the Effect of the AI500™ SINGLE-DOSE GEL Medical Device in Patients With Reduced Knee Function
Evaluation of the effect of the AI500™ SINGLE-DOSE GEL medical device in patients with reduced knee function
- Conditions
- Pain, Acute, Pain, Chronic, Knee Injuries, Knee Osteoarthritis
- Trial name
- NCT05886608
- Testing
- AI 500™ SINGLE-DOSE GEL
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Contrad Swiss SA
Malocclusion Class II, CLASS II DIVISION 1 MALOCCLUSION
A Novel Bi-dimensional Archwire for Miniscrew-supported En-masse Retraction
This study aims to provide a preliminary clinical evaluation of a novel bi-dimensional archwire used during miniscrew-supported en-masse retraction of the maxillary anterior teeth.
- Trial name
- NCT07664215
- Testing
- Bi-dimensional archwire
- Where
- Syria
- Volunteers
- 6 people
- Sponsor
- Damascus University
Postoperative Morbidity
Effects of Hyaluronic Acid Complex and Dexamethasone on Pain, Swelling, and Trismus After Mandibular Third Molar Surgery
This study aimed to comparatively evaluate the effects of a hyaluronic acid complex and dexamethasone on postoperative pain, swelling, and trismus following mandibular third molar surgery, compared with a control group.
- Trial name
- NCT07853196
- Testing
- Hyaluronic Acid Complex, Dexamethasone, Absorbable Hemostatic Gelatin Sponge (SPONGOSTAN™ Dental)
- Where
- Cyprus
- Volunteers
- 45 people
- Sponsor
- Cyprus Health and Social Sciences University
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
Selective Median Lobe Surgery Outcomes Study
This prospective multicenter observational cohort study will evaluate clinical outcomes after selective median lobe transurethral surgery for benign prostatic obstruction.
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH), Benign Prostatic Obstruction, Urinary Retention
- Trial name
- UNVEIL-BPO (NCT07699718)
- Testing
- Selective Median Lobe TURP, Selective Median Lobe HoLEP/AEEP
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 420 people
- Sponsor
- Necmettin Erbakan University
Lumbar Disc Herniation, Spinal Disk Injury
Decompression With ELDOA on Lumbar Disc Protrusion Patient
Decompression therapy is a result-oriented approach but it expensive and minimum availability in Pakistan. In physical therapy, we use different exercises to solve multiple spine problems.
- Conditions
- Lumbar Disc Herniation, Spinal Disk Injury, Protrusion
- Trial name
- NCT04760210
- Testing
- Control Group, Decompression Group, ELDOA
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Aqua Medical Services (Pvt) Ltd
Postoperative Pain, Third Molar
Effect of Oral Magnesium on Anesthesia and Postoperative Analgesia After Surgical Removal of the Lower Third Molars.
The operation of the lower third molars is one of the most common oral surgery procedures in the world. The surgery is mostly done in local anesthesia which makes the surgery as pleasant as possible for the patient.
- Conditions
- Postoperative Pain, Third Molar, Postoperative Complications
- Trial name
- NCT03398382
- Testing
- Magnesium tablet group, Magnesium lozenge group
- Where
- 2 sites in Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Daniel Jerković
Class III Malocclusion in Growing Patients
Changes Following the Treatment of Lower Jaw Protrusion Using Two Appliances
An in vivo study evaluating the efficacy of the Tandem appliance in the treatment of maxillary deficiency in growing patients compared to the conventional facemask appliance treatment.
- Trial name
- NCT02144324
- Testing
- Tandem Appliance
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Cervical Disc Herniation
Elongation Longitudinaux Avec Decoaption Osteo-Articulaire (ELDOA) in Cervical Disc Protrusion
The aim of this research is to find and compare the effect of conventional physical therapy and ELDOA stretching exercise on pain, range of motion and disability in patients with cervical disc protrusion.
- Trial name
- NCT04044092
- Testing
- Conservative physical therapy, ELDOA stretching exercise
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Osteoarthritis, Muscle Pain
An Bioequivalence Study of Loxoprofen Sodium Patches in Healthy Volunteers
This study was a single-center, randomized, open-label, two-agent, two-cycle, double-cross bioequivalence trial.
- Conditions
- Osteoarthritis, Muscle Pain, Swelling Muscle
- Trial name
- NCT06510413
- Testing
- Loxoprofen Sodium Patches(reference product), Loxoprofen Sodium Patches(test product )
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Frontier Biotechnologies Inc.
Ankle Fracture, Ankle Arthrodesis
Compression Therapy for Swelling Management Following Ankle Injury
After an injury or undergoing foot/ankle surgery, patients often experience swelling in the injured area. Under current standard of care, plaster casts are removed at six weeks and patients are put in a walking boot.
- Trial name
- NCT06772649
- Testing
- Compression sleeve
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Soft Tissue Injuries
Treatment of Posttraumatic Swelling and Pain With Zhi Kang Capsule
Zhi Kang Capsule functions for hemostasis and detumescence and can be used for traumatic bleeding, uterine bleeding, hematemesis and hematochezia.This randomized controlled trial was conducted to confirm the efficacy and safety…
- Trial name
- NCT03363971
- Testing
- Zhi Kang Capsule, Simulant agent for Zhi Kang Capsule
- Where
- China
- Volunteers
- 2,200 people
- Sponsor
- Peking University People's Hospital
Lower Extremity Edema, Lower Extremity Edema Chronic
Pedal Pump Clinical Trial on Edema V2
Previous research on the osteopathic manual technique entitled "Pedal Pump" has shown health benefits, specifically increasing lymphatic flow, decreasing lower extremity edema, and decreasing serum lactic acid after maximal…
- Conditions
- Lower Extremity Edema, Lower Extremity Edema Chronic, CHF - Congestive Heart Failure, CHF Exacerbation
- Trial name
- NCT07809516
- Testing
- Pedal Pump
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hillcrest
Swelling/ Edema, Impacted Third Molar Tooth
3D Evaluation of Facial Swelling Post Impacted Lower Third Molars Surgery: RCT
Aim of the study is to evaluate the swelling following the osteotomy when performed with drilling bur versus piezo-electric instrument in the mandibular impacted third molar extraction, using a facial reconstruction software
- Trial name
- NCT05488028
- Testing
- Piezo-electric surgery of impacted lower third molars, Rotary bur surgery of impacted lower third molars
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Breast Cancer, Lymphedema
Who and Why do Patients Report Lymphedema After Breast Cancer Treatment Without an Objective Measurable Swelling
Breast cancer related lymphedema (BCRL) at the arm and/or trunk is an extremely dreaded complication after breast cancer treatment due to its chronicity and impact.
- Conditions
- Breast Cancer, Lymphedema, Sensory Processing Disorder
- Trial name
- LymphSens (NCT06324721)
- Testing
- Measurements for breast cancer related lymphedema (volumetric measurements, bioimpedance spectroscopy, bioimpedance analysis, tissue dielectric constant measurements, ultrasonography), Measurements for lymphatic problems (volumetric measurements, tissue dielectric measurement, lymphofluoroscopy), Measurements for sensory processing problems by monofilaments, algometer, goniometer, and neurosensory analyzer
- Where
- Belgium
- Volunteers
- 230 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Venous Occlusion
Venous Occlusion and Limb Swelling
Problems affecting the veins in the legs can cause discomfort and swelling. We want to see how artificially and reversibly blocking the leg veins affects swelling in the lower limb.
- Trial name
- NCT02241343
- Testing
- Venous occlusion (leg tourniquet, made in-house)
- Where
- United Kingdom
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Pelvic Organ Prolapse
Clinical Trial of Solifenacin Versus Placebo Plus Pessary for Women With Vaginal Prolapse
This study will evaluate the effect of pessary therapy, with and without Solifenacin (Vesicare), on symptoms of over active bladder and bladder function in women with overactive bladder symptoms and pelvic organ prolapse.
- Trial name
- PESSARY (NCT01092624)
- Testing
- Solifenacin, Ring pessary with support, Cooper Surgical, Trumbell, CT Ref # MXPRS03 non-latex
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Hartford Hospital
Hip Impingement Syndrome, Prosthetic Complication
Retrospective Study on Radiological Factors Predictive of Psoas Impingement
The purpose of this study is to identify radiological factors on TC of the hip that could lead to prediction of development of symptomatic psoas impingement in patients with protruding acetabular cup after primary total hip…
- Trial name
- NCT05893823
- Testing
- Pelvis CT scan
- Where
- 2 sites in Italy
- Volunteers
- 52 people
- Sponsor
- Istituto Ortopedico Rizzoli
Dental Malocclusions, Angle Class II, Division 1
Flapless Mops for Acceleration of Canine Retraction
The aim of the present clinical study was directed to evaluate the effectiveness of micro-osteoperforations on the rate of canine retraction; in addition, the potential risk for root resorption during maxillary canine retraction.
- Conditions
- Dental Malocclusions, Angle Class II, Division 1, Bimaxillary Protrusion
- Trial name
- NCT04383600
- Testing
- Micro-osteoperforation
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Ahmed Akram Elawady
Breast Cancer
Multimodal Imaging Evaluation System of Axillary Lymph Node Staging and Treatment Strategy for Breast Cancer Neoadjuvant Therapy
In view of the lack of systematic curative effect prediction and early evaluation indicators for breast cancer neoadjuvant chemotherapy, the effective fusion of CEUS（contrast-enhanced ultrasound） and MRI is realized, and a…
- Trial name
- MIES-BCNAT (NCT04661436)
- Testing
- Contrast-Enhanced Ultrasound
- Volunteers
- 300 people
- Sponsor
- Sichuan Provincial People's Hospital
Bimaxillary Protrusion
Evaluation of the Rate of En-masse Retraction in Orthodontic Patients With Maxillary Protrusion
There's a scarcity in literature concerning en-masse retraction and its effect on the rate of tooth movement. The purpose of this study is to determine, In orthodontic patients with maxillary protrusion, which form of mechanics…
- Trial name
- NCT04902430
- Testing
- Power chain and Crimpable hook for En-Masse Retraction, T- Loop
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt